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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Chronic Intermittent Hypoxia
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Accession:DOID:9000288 term browser browse the term
Definition:This condition involves repetitive cycles of hypoxia and normoxia, which resembles the fluctuation of oxygen saturation in obstructive sleep apnea.
Synonyms:exact_synonym: CIH
 primary_id: RDO:9000063
For additional species annotation, visit the Alliance of Genome Resources.

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Chronic Intermittent Hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEP mRNA:increased expression:carotid body RGD PMID:24036592 RGD:11039031 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Agt angiotensinogen IEP mRNA, protein:increased expression:type I cell of carotid body RGD PMID:24036592 RGD:11039031 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:26769958 RGD:13792505 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA RGD PMID:26769958 RGD:13792505 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Becn1 beclin 1 IEP RGD PMID:24990154 RGD:11561988 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP RGD PMID:24990154 RGD:11561988 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:26769958 RGD:13792505 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Hk1 hexokinase 1 IEP mRNA, protein:increased expression:cardiac ventricle RGD PMID:24525799 RGD:11353961 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 IEP mRNA, protein:increased expression:cardiac ventricle RGD PMID:24525799 RGD:11353961 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Lpl lipoprotein lipase treatment IEP RGD PMID:29968701 RGD:13793400 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:24990154 RGD:11561988 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17289
    disease of anatomical entity 16625
      nervous system disease 12154
        central nervous system disease 10420
          brain disease 9782
            Brain Hypoxia 97
              Chronic Intermittent Hypoxia 11
paths to the root