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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Plaque, Atherosclerotic
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Accession:DOID:9000146 term browser browse the term
Definition:Lesions formed within the walls of ARTERIES.
Synonyms:exact_synonym: Arterial Fatty Streak;   Arterial Fatty Streaks;   Atheroma;   Atheromas;   Atheromatous Plaques;   Atherosclerotic Plaques;   Fibroatheroma;   Fibroatheromas;   Fibroatheromatous Plaque;   Fibroatheromatous Plaques
 primary_id: MESH:D058226;   RDO:0007814
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
Plaque, Atherosclerotic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17438151 PMID:18093987 PMID:19124646 PMID:20720404 PMID:22770994 PMID:22869926 PMID:24330719 PMID:24933211 PMID:29355567 PMID:29425287 PMID:30376133 PMID:30533443 PMID:32853627 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Bsg basigin (Ok blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18647594 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO protein:decreased expression:endothelial cell,macrophage: RGD PMID:10623660 RGD:11341688 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Ephx2 epoxide hydrolase 2 susceptibility ISO DNA:SNPs, haplotypes:exon, intron:p.R287Q, IVS11-883C>G (rs751141, rs721619) (human) RGD PMID:16545818 RGD:5688389 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fermt3 FERM domain containing kindlin 3 severity ISO mRNA:increased expression:artery RGD PMID:26188538 RGD:11085957 NCBI chr 1:222,254,183...222,272,775
Ensembl chr 1:222,254,184...222,272,285
JBrowse link
G Igf1 insulin-like growth factor 1 treatment ISO RGD PMID:17916769 RGD:8548877 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Itgb2 integrin subunit beta 2 ISO mRNA:increased expression:artery RGD PMID:26188538 RGD:11085957 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itgb3 integrin subunit beta 3 severity ISO DNA:SNP: :rs5918(human) RGD PMID:21353223 RGD:13602095 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:30996006 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29425287 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18093987 PMID:19124646 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Sp1 Sp1 transcription factor ISO protein:increased phosphorylation:smooth muscle cell: RGD PMID:18258854 RGD:9854624 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Tlr2 toll-like receptor 2 ISO associated with Plaque,Atherosclerotic;mRNA:increased expression:mononuclear cell: RGD PMID:23457721 RGD:7777173 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 ISO associated with Plaque,Atherosclerotic;mRNA:increased expression:mononuclear cell: RGD PMID:23457721 RGD:7777173 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  disease 17126
    Pathological Conditions, Signs and Symptoms 10186
      Anatomical Pathological Conditions 1989
        Plaque, Atherosclerotic 14
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