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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Paranasal Sinus Neoplasms
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Accession:DOID:9000118 term browser browse the term
Definition:Tumors or cancer of the PARANASAL SINUSES.
Synonyms:exact_synonym: neoplasm of accessory sinus;   paranasal sinus neoplasms;   tumor of accessory sinus
 primary_id: MESH:D010255
 xref: NCI:C7488


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maxillary sinus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A IEP RGD PMID:15040115 RGD:8662355 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
nasal cavity adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLU clusterin IEP RGD PMID:19903339 RGD:9014708 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
nasal cavity cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOX2 SRY-box transcription factor 2 IAGP DNA:amplification RGD PMID:23544055 RGD:8661654 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G TP53 tumor protein p53 IAGP RGD PMID:19950227 RGD:8547762 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
nasal type extranodal NK/T-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 severity IEP Nasal Type;protein:increased expression:nasal cavity (human) RGD PMID:18756548 RGD:8657087 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G CD274 CD274 molecule disease_progression IEP associated with Epstein-Barr Virus Infections RGD PMID:27595782 RGD:41412182 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:15924153 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G FAS Fas cell surface death receptor IAGP DNA:insertion, deletions:cds:multiple (human) RGD PMID:12466128 RGD:8662407 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G GPX3 glutathione peroxidase 3 treatment IEP associated with ethmoid sinus cancer and Neoplasm Metastasis RGD PMID:29496492 RGD:151708712 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G JAK3 Janus kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22705984 PMID:23689514 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G PRDM1 PR/SET domain 1 disease_progression IEP RGD PMID:24438193 RGD:150530467 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEP protein:increased expression:nasal cavity (human) RGD PMID:17225522 RGD:153298933 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29200404 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
paranasal sinus benign neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 IEP RGD PMID:20970165 RGD:7421559 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G ANXA2 annexin A2 disease_progression IEP RGD PMID:20970165 RGD:7421559 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G TP53 tumor protein p53 treatment IAGP DNA:mutations:cds: RGD PMID:22575263 PMID:23369851 RGD:8547763, RGD:8547764 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
sinonasal undifferentiated carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAML3 mastermind like transcriptional coactivator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24859338 NCBI chr 4:139,716,753...140,154,184
Ensembl chr 4:139,716,753...140,154,184 		JBrowse link
G PAX3 paired box 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24859338 NCBI chr 2:222,199,887...222,298,998
Ensembl chr 2:222,199,887...222,298,998 		JBrowse link
G SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 IEP RGD PMID:30120966 RGD:127285653 NCBI chr22:23,786,966...23,838,009
Ensembl chr22:23,786,931...23,838,009 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 41189
    sensory system disease 9730
      Otorhinolaryngologic Diseases 2281
        nose disease 236
          paranasal sinus disease 62
            Paranasal Sinus Neoplasms 18
              Maxillary Sinus Neoplasms + 1
              Sinonasal Neoplasms + 15
              paranasal sinus benign neoplasm + 3
              paranasal sinus cancer + 4
Path 2
Term Annotations click to browse term
  disease 41189
    disease of anatomical entity 32344
      musculoskeletal system disease 11642
        connective tissue disease 7446
          bone disease 5601
            Bone Neoplasms 1243
              Skull Neoplasms 31
                Nose Neoplasms 20
                  Paranasal Sinus Neoplasms 18
                    Maxillary Sinus Neoplasms + 1
                    Sinonasal Neoplasms + 15
                    paranasal sinus benign neoplasm + 3
                    paranasal sinus cancer + 4
paths to the root