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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Headache
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Accession:DOID:9000053 term browser browse the term
Definition:The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
Synonyms:exact_synonym: Bilateral Headache;   Bilateral Headaches;   Cephalalgia;   Cephalalgias;   Cephalgia;   Cephalgias;   Cephalodynia;   Cephalodynias;   Cranial Pain;   Cranial Pains;   Generalized Headache;   Generalized Headaches;   Head Pain;   Head Pains;   Headaches;   Hemicrania;   Ocular Headache;   Ocular Headaches;   Orthostatic Headache;   Orthostatic Headaches;   Periorbital Headache;   Periorbital Headaches;   Retro Ocular Headache;   Retro-Ocular Headaches;   Sharp Headache;   Sharp Headaches;   Throbbing Headache;   Throbbing Headaches;   Unilateral Headache;   Unilateral Headaches;   Vertex Headache;   Vertex Headaches
 primary_id: MESH:D006261;   RDO:0005719
For additional species annotation, visit the Alliance of Genome Resources.



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Headache term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10864982 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Fkrp fukutin related protein ISO ClinVar Annotator: match by term: Headaches ClinVar PMID:11741828 PMID:12666124 PMID:14647208 PMID:15060126 PMID:15574464 More... NCBI chr 1:77,479,641...77,486,954
Ensembl chr 1:77,476,084...77,486,992
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12910066 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7537110 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:7080326 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21036476 RGD:5131274 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein ISO DNA:missense mutation: :p.H611R (human) RGD PMID:17719176 RGD:8694403 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17435
    Pathological Conditions, Signs and Symptoms 10360
      Signs and Symptoms 6553
        Neurologic Manifestations 5497
          Pain 315
            Headache 7
              Cutaneous Hyperthermia with Headaches and Nausea 0
              Slit Ventricle Syndrome 0
paths to the root