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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Spinal Cord Injuries
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Accession:DOID:9000039 term browser browse the term
Definition:Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Synonyms:exact_synonym: Post Traumatic Myelopathy;   Post-Traumatic Myelopathies;   Spinal Cord Contusion;   Spinal Cord Contusions;   Spinal Cord Injury;   Spinal Cord Laceration;   Spinal Cord Lacerations;   Spinal Cord Transection;   Spinal Cord Transections;   Spinal Cord Trauma;   Spinal Cord Traumas;   Traumatic Myelopathies;   Traumatic Myelopathy
 narrow_synonym: acute spinal cord injury
 primary_id: MESH:D013119;   RDO:0006597
For additional species annotation, visit the Alliance of Genome Resources.



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Spinal Cord Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1810013A23Rik RIKEN cDNA 1810013A23 gene ISO RGD PMID:20058304 RGD:2324875 NCBI chr17:28,271,708...28,273,163
Ensembl chr17:28,232,700...28,301,474
JBrowse link
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 treatment ISO
IMP
mRNA:increased expression:spinal cord RGD PMID:20410530 PMID:25763638 PMID:20410530 PMID:20410530 RGD:12790978, RGD:12791993, RGD:12790978, RGD:12790978 NCBI chr 7:46,104,523...46,180,039
Ensembl chr 7:46,104,523...46,180,033
JBrowse link
G Acan aggrecan ISO protein:altered expression:spinal cord (rat) RGD PMID:14769391 RGD:2315837 NCBI chr 7:79,053,226...79,115,099
Ensembl chr 7:79,053,483...79,115,099
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 ISO RGD PMID:20456005 RGD:10755338 NCBI chr10:77,290,727...77,418,292
Ensembl chr10:77,290,726...77,418,270
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO protein:altered expression:spinal cord,dorsal root ganglion, urinary bladder RGD PMID:15698618 PMID:15913892 RGD:2325309, RGD:2325306 NCBI chr17:93,198,245...93,206,541
Ensembl chr17:93,199,017...93,206,537
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16213239 RGD:5686719 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Adora1 adenosine A1 receptor ISO protein:decreased expression:spinal cord RGD PMID:18289533 PMID:17853654 RGD:5129096, RGD:4890369 NCBI chr 1:134,199,215...134,235,457
Ensembl chr 1:134,199,223...134,235,431
JBrowse link
G Adora2a adenosine A2a receptor ISO RGD PMID:17559837 RGD:4890378 NCBI chr10:75,316,877...75,334,792
Ensembl chr10:75,316,877...75,334,784
JBrowse link
G Adra1a adrenergic receptor, alpha 1a ISO mRNA:increased expression:aorta RGD PMID:16524515 RGD:5688371 NCBI chr14:66,635,251...66,771,240
Ensembl chr14:66,635,251...66,771,168
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:spinal cord (rat) RGD PMID:20195207 RGD:2325645 NCBI chr17:34,597,460...34,600,937
Ensembl chr17:34,597,862...34,600,936
JBrowse link
G Aif1 allograft inflammatory factor 1 ISO protein:altered expression:spinal cord dorsal horn (rat) RGD PMID:17158026 RGD:2313037 NCBI chr17:35,170,986...35,176,083
Ensembl chr17:35,170,991...35,176,068
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 ISO RGD PMID:20678995 RGD:10040962 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Akt1s1 AKT1 substrate 1 (proline-rich) ISO CTD Direct Evidence: therapeutic CTD PMID:17457363 NCBI chr 7:44,849,224...44,855,421
Ensembl chr 7:44,848,991...44,855,421
JBrowse link
G Ambra1 autophagy/beclin 1 regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chr 2:91,730,138...91,918,849
Ensembl chr 2:91,730,134...91,918,849
JBrowse link
G Ankrd1 ankyrin repeat domain 1 (cardiac muscle) ISO mRNA:increased expression:spinal cord, dorsal root ganglion, neuron RGD PMID:17610582 RGD:5133279 NCBI chr19:36,111,965...36,119,844
Ensembl chr19:36,111,961...36,120,099
JBrowse link
G Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B ISO RGD PMID:25034417 RGD:10401137 NCBI chr 4:46,450,926...46,472,657
Ensembl chr 4:46,450,902...46,472,657
JBrowse link
G Anxa1 annexin A1 treatment ISO mRNA,protein:increased expression:neuron,glial cell RGD PMID:17917587 PMID:15248295 RGD:2306891, RGD:10053688 NCBI chr19:20,373,434...20,390,671
Ensembl chr19:20,373,428...20,390,944
JBrowse link
G Anxa2 annexin A2 ISO mRNA,protein:increased expression:neuron,glial cell RGD PMID:15248295 RGD:10053688 NCBI chr 9:69,453,683...69,491,792
Ensembl chr 9:69,453,620...69,491,795
JBrowse link
G Anxa5 annexin A5 ISO mRNA,protein:increased expression:neuron,glial cell RGD PMID:15248295 RGD:10053688 NCBI chr 3:36,448,923...36,475,887
Ensembl chr 3:36,448,923...36,475,894
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO RGD PMID:21748659 RGD:10053608 NCBI chr10:90,989,311...91,082,743
Ensembl chr10:90,989,311...91,082,770
JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 ISO mRNA:increased expression:spinal cord RGD PMID:18637713 RGD:2315670 NCBI chr14:50,924,949...50,927,188
Ensembl chr14:50,924,968...50,927,139
JBrowse link
G Apoe apolipoprotein E ISO DNA:polymorphism:exon: RGD PMID:18581664 PMID:30036659 RGD:7771551, RGD:13703128 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Aqp1 aquaporin 1 ISO protein:increased expression:spinal cord, neuron, astrocyte
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21092735 PMID:18248364 PMID:21092735 RGD:2307072, RGD:5148013 NCBI chr 6:55,336,299...55,348,555
Ensembl chr 6:55,336,432...55,348,555
JBrowse link
G Aqp4 aquaporin 4 ISO
IEP
IMP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21092735 PMID:21092735 PMID:21280976 PMID:20517941 RGD:5148013, RGD:5148035, RGD:5148027 NCBI chr18:15,389,394...15,410,982
Ensembl chr18:15,389,496...15,410,982
JBrowse link
G Atf4 activating transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
G Atg5 autophagy related 5 ISO protein:increased expression:axon
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29793971 PMID:25040536 RGD:11553820 NCBI chr10:44,268,322...44,364,299
Ensembl chr10:44,268,358...44,364,291
JBrowse link
G Atg7 autophagy related 7 ISO protein:increased expression:axon RGD PMID:25040536 RGD:11553820 NCBI chr 6:114,643,127...114,860,604
Ensembl chr 6:114,643,097...114,860,614
JBrowse link
G Atm ataxia telangiectasia mutated ISO protein:increased expression:spinal cord RGD PMID:21748659 RGD:10053608 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 ISO protein:decreased expression:tail, skeletal muscle RGD PMID:21930674 RGD:13782071 NCBI chr 7:126,445,858...126,463,103
Ensembl chr 7:126,445,858...126,463,108
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 ISO protein:decreased expression:tail, skeletal muscle RGD PMID:21930674 RGD:13782071 NCBI chr 5:122,453,513...122,502,225
Ensembl chr 5:122,453,513...122,502,225
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO mRNA,protein:decreased expression:spinal cord: RGD PMID:28035406 RGD:14390163 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcan brevican treatment ISO RGD PMID:15016081 RGD:9589823 NCBI chr 3:87,987,531...88,002,175
Ensembl chr 3:87,987,531...88,000,230
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bdnf brain derived neurotrophic factor treatment ISO RGD PMID:16022868 PMID:24551172 PMID:19203225 RGD:4891112, RGD:10059354, RGD:4891066 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Becn1 beclin 1, autophagy related treatment IEP
ISO
protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29793971 PMID:21806471 PMID:23852559 PMID:24559459 RGD:6483100, RGD:11561922, RGD:11561918 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO RGD PMID:23770801 RGD:9068404 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp4 bone morphogenetic protein 4 treatment ISO RGD PMID:23770801 PMID:18803859 RGD:9068404, RGD:9068437 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 ISO protein:increased expression:spinal cord RGD PMID:23637053 RGD:11564330 NCBI chr 7:138,890,836...138,909,506
Ensembl chr 7:138,890,836...138,909,519
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like ISO protein:increased expression:spinal cord RGD PMID:23637053 RGD:11564330 NCBI chr14:66,985,238...67,008,877
Ensembl chr14:66,985,239...67,008,877
JBrowse link
G Brca2 breast cancer 2, early onset ISO mRNA,protein:increased expression:spinal cord: RGD PMID:21748659 RGD:10053608 NCBI chr 5:150,522,297...150,570,147
Ensembl chr 5:150,522,630...150,570,329
JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide ISO mRNA:increased expression RGD PMID:16345062 RGD:1599510 NCBI chr 4:136,880,126...136,886,200
Ensembl chr 4:136,880,129...136,886,187
JBrowse link
G Capn1 calpain 1 treatment ISO RGD PMID:23102374 RGD:13792496 NCBI chr19:5,988,545...6,015,825
Ensembl chr19:5,988,545...6,015,897
JBrowse link
G Capzb capping protein (actin filament) muscle Z-line, beta ISO protein:decreased expression:spinal cord RGD PMID:20141154 RGD:9685028 NCBI chr 4:139,192,899...139,291,820
Ensembl chr 4:139,192,899...139,291,818
JBrowse link
G Casp1 caspase 1 ISO protein:increased expression, increased activation:spinal cord RGD PMID:18367607 RGD:2315889 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp12 caspase 12 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:19215662 PMID:26884858 RGD:2311450, RGD:11560925 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:14588118 PMID:18378144 PMID:27256506 PMID:27339639 PMID:21748659 RGD:2293322, RGD:13792677, RGD:13782345, RGD:10053608 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:21748659 PMID:27339639 RGD:10053608, RGD:13782345 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cav1 caveolin 1, caveolae protein ISO protein:increased phosphorylation:spinal cord RGD PMID:17275798 RGD:2289124 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 ISO mRNA:increased expression:spinal cord RGD PMID:9698165 RGD:5135274 NCBI chr11:82,101,845...82,103,399
Ensembl chr11:82,101,845...82,103,400
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 IEP mRNA:increased expression:spinal cord segment (mouse) RGD PMID:20478301 RGD:4889905 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Ccnd3 cyclin D3 ISO protein:increased expression:spinal cord RGD PMID:18008145 RGD:2316019 NCBI chr17:47,505,051...47,599,689
Ensembl chr17:47,505,051...47,599,691
JBrowse link
G Ccne1 cyclin E1 ISO protein:increased expression:spinal cord RGD PMID:16759516 RGD:2289281 NCBI chr 7:38,097,984...38,107,490
Ensembl chr 7:38,097,984...38,107,534
JBrowse link
G Ccnh cyclin H ISO mRNA, protein:increased expression:spinal cord RGD PMID:21710280 RGD:9590263 NCBI chr13:85,189,377...85,213,731
Ensembl chr13:85,189,408...85,223,469
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 ISO RGD PMID:21332278 RGD:5688138 NCBI chr 9:123,962,126...123,968,692
Ensembl chr 9:123,962,124...123,968,692
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 ISO protein:increased expression:spinal cord RGD PMID:18338959 RGD:4144888 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Cd274 CD274 antigen ISO mRNA:increased expression:microglial cell RGD PMID:29665726 RGD:40886268 NCBI chr19:29,362,107...29,388,095
Ensembl chr19:29,367,455...29,388,095
JBrowse link
G Cdc42 cell division cycle 42 ISO mRNA:increased expression:spinal cord RGD PMID:15736231 RGD:5688276 NCBI chr 4:137,319,696...137,357,759
Ensembl chr 4:137,319,696...137,357,720
JBrowse link
G Cdk1 cyclin-dependent kinase 1 ISO protein:increased expression:spinal cord dura mater (rat) RGD PMID:19672039 RGD:2316488 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938
JBrowse link
G Cdk19 cyclin-dependent kinase 19 ISO mRNA, protein:increased expression:spinal cord RGD PMID:18008145 RGD:2316019 NCBI chr10:40,349,287...40,483,818
Ensembl chr10:40,339,564...40,483,818
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO protein:decreased expression, altered localization:spinal cord, neuron, microglial cell RGD PMID:18319192 RGD:2293615 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Chl1 cell adhesion molecule L1-like ISO protein:increased expression:spinal cord (rat) RGD PMID:21337374 RGD:6483045 NCBI chr 6:103,510,584...103,733,038
Ensembl chr 6:103,510,586...103,750,211
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) ISO RGD PMID:18930143 RGD:2316199 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) ISO RGD PMID:18930143 RGD:2316199 NCBI chr 4:135,895,189...135,920,219
Ensembl chr 4:135,895,394...135,920,207
JBrowse link
G Cr2 complement receptor 2 ISO protein:increased expression:cerebrospinal fluid RGD PMID:26502875 RGD:11343913 NCBI chr 1:195,136,811...195,176,880
Ensembl chr 1:195,136,811...195,176,716
JBrowse link
G Crh corticotropin releasing hormone ISO protein:altered expression:spinal cord (rat) RGD PMID:20458328 RGD:5490964 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO RGD PMID:22404382 RGD:6903321 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) treatment ISO RGD PMID:15658127 RGD:10449531 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO RGD PMID:21953623 RGD:10450511 NCBI chr11:98,700,183...98,703,631
Ensembl chr11:98,701,263...98,703,629
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IDA
ISO
RGD PMID:22243800 PMID:19604403 PMID:22042562 RGD:5686844, RGD:5686859, RGD:5686848 NCBI chr 9:56,865,104...56,899,870
Ensembl chr 9:56,865,033...56,899,870
JBrowse link
G Ctss cathepsin S ISO RGD PMID:16344894 RGD:2303423 NCBI chr 3:95,526,786...95,556,405
Ensembl chr 3:95,526,786...95,556,403
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 ISO RGD PMID:9698165 RGD:5135274 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 ISO RGD PMID:19170890 RGD:2311365 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide ISO mRNA:increased expression:spinal cord RGD PMID:16345062 RGD:1599510 NCBI chr 8:122,424,771...122,432,940
Ensembl chr 8:122,424,776...122,432,930
JBrowse link
G Cybb cytochrome b-245, beta polypeptide IEP mRNA,protein:increased expression:microglia: RGD PMID:20679217 RGD:11040629 NCBI chr  X:9,435,252...9,487,766
Ensembl chr  X:9,435,252...9,487,771
JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein ISO protein:increased expression:spinal cord RGD PMID:17317100 RGD:7243246 NCBI chr15:6,299,788...6,440,715
Ensembl chr15:6,299,788...6,440,712
JBrowse link
G Dcc deleted in colorectal carcinoma ISO RGD PMID:16998900 RGD:2314373 NCBI chr18:71,253,613...72,351,228
Ensembl chr18:71,253,634...72,351,069
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Dusp1 dual specificity phosphatase 1 treatment ISO protein:decreased expression:spinal cord RGD PMID:18630599 PMID:19383246 RGD:7771572, RGD:7771580 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Efnb2 ephrin B2 ISO mRNA,protein:increased expression:fibroblast, astrocyte
protein:increased phosporylation:spinal cord
RGD PMID:33794069 PMID:12944508 RGD:127285659, RGD:127285804 NCBI chr 8:8,617,235...8,661,242
Ensembl chr 8:8,617,434...8,661,242
JBrowse link
G Egfr epidermal growth factor receptor ISO protein:increased phosphorylation:spinal cord, astrocyte (rat) RGD PMID:20869112 PMID:21402118 RGD:5131525, RGD:5131454 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A ISO mRNA, protein:increased expression:gastrocnemius RGD PMID:23238062 RGD:10395360 NCBI chr11:69,916,712...69,921,958
Ensembl chr11:69,916,714...69,921,958
JBrowse link
G Endog endonuclease G ISO RGD PMID:16689664 RGD:8655990 NCBI chr 2:30,171,408...30,174,069
Ensembl chr 2:30,171,493...30,174,069
JBrowse link
G Eno2 enolase 2, gamma neuronal ISO protein:increased expression:serum, cerebrospinal fluid RGD PMID:18343116 RGD:2293743 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673
JBrowse link
G Ensa endosulfine alpha ISO mRNA:decreased expression:spinal cord RGD PMID:16344894 RGD:2303423 NCBI chr 3:95,624,980...95,632,117
Ensembl chr 3:95,624,993...95,632,102
JBrowse link
G Epha3 Eph receptor A3 ISO RGD PMID:16083359 RGD:2301766 NCBI chr16:63,543,532...63,864,175
Ensembl chr16:63,543,534...63,864,175
JBrowse link
G Epha4 Eph receptor A4 ISO
IMP
RGD PMID:17970742 PMID:17418490 PMID:21931787 RGD:5688750, RGD:5688782, RGD:5688764 NCBI chr 1:77,367,182...77,515,107
Ensembl chr 1:77,367,185...77,515,088
JBrowse link
G Epha7 Eph receptor A7 ISO mRNA:increased expression:spinal cord RGD PMID:16983667 RGD:2301957 NCBI chr 4:28,813,066...28,967,503
Ensembl chr 4:28,813,131...28,967,499
JBrowse link
G Ephb2 Eph receptor B2 ameliorates ISO RGD PMID:33794069 PMID:12944508 RGD:127285659, RGD:127285804 NCBI chr 4:136,647,536...136,836,326
Ensembl chr 4:136,647,539...136,835,988
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:22196867 RGD:10401074 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO mRNA, protein:increased expression:spinal cord RGD PMID:11797086 RGD:2289967 NCBI chr10:128,567,523...128,589,635
Ensembl chr10:128,567,523...128,589,652
JBrowse link
G Esr1 estrogen receptor 1 (alpha) ISO RGD PMID:25105782 RGD:10045844 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO RGD PMID:25105782 RGD:10045844 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G F2 coagulation factor II ISO RGD PMID:16344894 RGD:2303423 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain treatment ISO RGD PMID:23574812 RGD:11344882 NCBI chr 7:144,578,323...144,582,441
Ensembl chr 7:144,577,318...144,582,463
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) ISO protein:increased expression:cervical spinal cord RGD PMID:17703359 PMID:29738767 PMID:17518537 RGD:2290176, RGD:13792580, RGD:2290177 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO Human FGF1 used in rat model of spinal cord injury RGD PMID:21663406 PMID:18482974 PMID:20488178 PMID:8662542 RGD:5509875, RGD:2317692, RGD:5509877, RGD:5509876 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Fgf2 fibroblast growth factor 2 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108
JBrowse link
G Fis1 fission, mitochondrial 1 treatment ISO RGD PMID:26079325 RGD:12437066 NCBI chr 5:136,953,275...136,966,234
Ensembl chr 5:136,953,275...136,966,234
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 ISO mRNA:increased expression:spinal cord, astrocyte, macrophage RGD PMID:17409380 RGD:5684414 NCBI chr 5:147,561,604...147,726,438
Ensembl chr 5:147,561,604...147,726,011
JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:20347014 RGD:7205459 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G Foxo3 forkhead box O3 ISO protein:decreased expression:spinal cord,neuron, astrocyte: RGD PMID:22930444 RGD:10402202 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Foxp3 forkhead box P3 treatment ISO RGD PMID:30287503 RGD:38549580 NCBI chr  X:7,579,676...7,595,243
Ensembl chr  X:7,573,644...7,595,245
JBrowse link
G Gap43 growth associated protein 43 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chr16:42,248,552...42,340,651
Ensembl chr16:42,248,442...42,340,651
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467
JBrowse link
G Gdnf glial cell line derived neurotrophic factor IDA RGD PMID:22342994 RGD:5688774 NCBI chr15:7,810,048...7,837,580
Ensembl chr15:7,810,846...7,837,575
JBrowse link
G Gfap glial fibrillary acidic protein treatment IMP
ISO
protein:increased expression:spinal cord RGD PMID:10225952 PMID:24968269 PMID:21250919 RGD:6480471, RGD:40924652, RGD:6480511 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:25261791 RGD:12907564 NCBI chr 3:27,371,351...27,379,235
Ensembl chr 3:27,371,351...27,378,010
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment ISO RGD PMID:23403365 PMID:24183749 RGD:8662431, RGD:8662460 NCBI chr10:56,377,300...56,390,419
Ensembl chr10:56,377,330...56,402,513
JBrowse link
G Gjc2 gap junction protein, gamma 2 treatment ISO RGD PMID:26415641 RGD:13208513 NCBI chr11:59,175,564...59,183,213
Ensembl chr11:59,175,568...59,183,213
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial ISO protein:increased expression:spinal cord (rat) RGD PMID:27150525 RGD:13506243 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO RGD PMID:22975889 RGD:8552988 NCBI chr 5:139,423,150...139,427,800
Ensembl chr 5:139,423,151...139,427,800
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO protein:increased expression:spinal cord, neuron, microglial cell (rat) RGD PMID:23359120 RGD:13792782 NCBI chr13:55,445,072...55,460,927
Ensembl chr13:55,445,072...55,460,927
JBrowse link
G Grn granulin IEP mRNA, protein:increased expression:spinal cord: RGD PMID:19946692 RGD:5509603 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Gsta4 glutathione S-transferase, alpha 4 ISO mRNA:increased expression:lumbar segment of spinal cord (rat) RGD PMID:22160604 RGD:5687769 NCBI chr 9:78,191,966...78,209,349
Ensembl chr 9:78,182,774...78,209,349
JBrowse link
G Hgf hepatocyte growth factor treatment ISO mRNA,protein:increased expression:spinal cord: RGD PMID:22140459 PMID:17549731 PMID:17549731 RGD:8548666, RGD:2317487, RGD:2317487 NCBI chr 5:16,553,495...16,619,439
Ensembl chr 5:16,553,495...16,620,152
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21092735 PMID:21092735 RGD:5148013 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hmgb1 high mobility group box 1 ISO mRNA:increased expression:spinal cord RGD PMID:20195207 RGD:2325645 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:23943397 RGD:10766443 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:16671478 RGD:1626425 NCBI chr 2:180,099,465...180,104,484
Ensembl chr 2:180,099,465...180,104,488
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 ISO protein:decreased expression:spinal cord (rat) RGD PMID:24499940 RGD:10445836 NCBI chr17:45,567,778...45,573,261
Ensembl chr17:45,567,775...45,573,271
JBrowse link
G Hspa5 heat shock protein 5 IEP mRNA: increased expression RGD PMID:21933012 RGD:5685666 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspb1 heat shock protein 1 treatment ISO mRNA,protein:increased expression:spinal cord: RGD PMID:12098653 PMID:30287503 RGD:10402749, RGD:38549580 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:8627308 RGD:11522712 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO mRNA:increased expression:spinal cord (rat) RGD PMID:11746449 RGD:9686138 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Id2 inhibitor of DNA binding 2 ISO mRNA:increased expression:spinal cord (rat) RGD PMID:11746449 RGD:9686138 NCBI chr12:25,093,799...25,096,092
Ensembl chr12:25,093,799...25,097,140
JBrowse link
G Id3 inhibitor of DNA binding 3 ISO mRNA:increased expression:spinal cord (rat) RGD PMID:11746449 RGD:9686138 NCBI chr 4:136,143,822...136,145,392
Ensembl chr 4:136,143,497...136,145,755
JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:29691718 RGD:14975124 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:18367607 PMID:23140983 RGD:2315889, RGD:8655974 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il1b interleukin 1 beta treatment ISO mRNA, protein:increased expression:spinal cord RGD PMID:16038625 PMID:29691718 PMID:23209732 RGD:1626673, RGD:14975124, RGD:7175523 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1r1 interleukin 1 receptor, type I ISO mRNA,protein:increased expression:spinal cord RGD PMID:16456668 RGD:7207035 NCBI chr 1:40,222,480...40,316,201
Ensembl chr 1:40,225,080...40,317,257
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:serum (human) RGD PMID:16038625 PMID:17964877 RGD:1626673, RGD:6907102 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il4 interleukin 4 ISO RGD PMID:20623539 RGD:5128562 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il4ra interleukin 4 receptor, alpha ISO mRNA:increased expression:spinal cord RGD PMID:20623539 RGD:5128562 NCBI chr 7:125,552,271...125,579,474
Ensembl chr 7:125,552,120...125,579,474
JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:27085942 PMID:29691718 RGD:11062150, RGD:14975124 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Irf1 interferon regulatory factor 1 ISO RGD PMID:11723173 RGD:2298928 NCBI chr11:53,770,014...53,778,374
Ensembl chr11:53,770,014...53,778,374
JBrowse link
G Irf5 interferon regulatory factor 5 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chr 6:29,526,130...29,541,869
Ensembl chr 6:29,526,625...29,541,871
JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 severity ISO protein:decreased expression:cerebrospinal fluid RGD PMID:21559420 RGD:40907059 NCBI chr14:30,886,476...30,901,986
Ensembl chr14:30,886,476...30,902,353
JBrowse link
G Jak2 Janus kinase 2 treatment ISO RGD PMID:23274522 RGD:10411896 NCBI chr19:29,251,803...29,313,095
Ensembl chr19:29,251,828...29,313,080
JBrowse link
G Jun jun proto-oncogene ISO protein:increased phosphorylation:neuron RGD PMID:21132399 RGD:4889994 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 ISO protein:decreased expression:spinal cord RGD PMID:20375134 RGD:8662905 NCBI chr 1:172,341,210...172,374,085
Ensembl chr 1:172,341,210...172,374,085
JBrowse link
G Kcnk2 potassium channel, subfamily K, member 2 treatment ISO RGD PMID:22425721 RGD:9831183 NCBI chr 1:189,207,930...189,402,782
Ensembl chr 1:189,207,930...189,402,273
JBrowse link
G Kdm6b KDM1 lysine (K)-specific demethylase 6B ISO mRNA:increased expression:spinal cord (rat) RGD PMID:22578249 RGD:9587821 NCBI chr11:69,398,508...69,420,367
Ensembl chr11:69,398,508...69,413,675
JBrowse link
G Kdr kinase insert domain protein receptor ISO mRNA:increased expression:spinal cord, astrocyte, macrophage RGD PMID:17409380 RGD:5684414 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Kif3b kinesin family member 3B ISO protein:increased expression:spinal cord RGD PMID:23093447 RGD:11049594 NCBI chr 2:153,291,395...153,333,390
Ensembl chr 2:153,291,413...153,333,390
JBrowse link
G Klk6 kallikrein related-peptidase 6 ISO protein:increased expression:spinal cord RGD PMID:16987227 RGD:2314866 NCBI chr 7:43,824,438...43,832,027
Ensembl chr 7:43,824,499...43,832,030
JBrowse link
G Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) ISO mRNA,protein:increased expression:spinal cord: RGD PMID:26524415 RGD:13703043 NCBI chr 1:175,632,193...175,660,853
Ensembl chr 1:175,620,381...175,662,116
JBrowse link
G Lep leptin ISO RGD PMID:19777863 RGD:5128780 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 treatment ISO RGD PMID:23867460 RGD:13800520 NCBI chr10:127,538,157...127,621,148
Ensembl chr10:127,538,161...127,621,148
JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 treatment ISO RGD PMID:24090150 RGD:12798566 NCBI chr19:3,584,825...3,686,585
Ensembl chr19:3,584,828...3,686,564
JBrowse link
G Lum lumican ISO protein:increased expression:spinal cord RGD PMID:18482974 RGD:2317692 NCBI chr10:97,565,501...97,572,703
Ensembl chr10:97,565,128...97,572,703
JBrowse link
G Map1b microtubule-associated protein 1B ISO protein:increased phosphorylation:spinal cord, neuron RGD PMID:17880387 RGD:2304007 NCBI chr13:99,421,464...99,516,602
Ensembl chr13:99,421,446...99,516,540
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO protein:increased expression:spinal cord RGD PMID:24559459 PMID:23637053 PMID:23852559 RGD:11561918, RGD:11564330, RGD:11561922 NCBI chr 2:155,276,364...155,278,073
Ensembl chr 2:155,276,297...155,278,073
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chr 8:121,590,438...121,598,760
Ensembl chr 8:121,590,361...121,598,760
JBrowse link
G Map2 microtubule-associated protein 2 ISO RGD PMID:21704982 RGD:6483323 NCBI chr 1:66,175,202...66,442,583
Ensembl chr 1:66,175,273...66,442,583
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO protein:increased expression:white matter and grey matter: RGD PMID:10331432 RGD:10412645 NCBI chr10:19,934,101...20,142,750
Ensembl chr10:19,934,472...20,142,753
JBrowse link
G Mapt microtubule-associated protein tau treatment ISO RGD PMID:22052241 RGD:8158113 NCBI chr11:104,229,409...104,332,090
Ensembl chr11:104,231,390...104,332,090
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 ISO protein:increased expression:spinal cord RGD PMID:23595775 RGD:10412063 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Met met proto-oncogene ISO mRNA, protein:increased expression:spinal cord (rat) RGD PMID:17549731 RGD:2317487 NCBI chr 6:17,463,349...17,573,980
Ensembl chr 6:17,463,800...17,573,980
JBrowse link
G Mfn1 mitofusin 1 treatment ISO protein:altered expression:spinal cord, mitochondrion (rat) RGD PMID:26981103 PMID:26079325 RGD:12910837, RGD:12437066 NCBI chr 3:32,529,443...32,579,225
Ensembl chr 3:32,529,465...32,579,239
JBrowse link
G Mfn2 mitofusin 2 treatment ISO protein:increased expression:spinal cord (rat) RGD PMID:28404953 PMID:26079325 RGD:12910735, RGD:12437066 NCBI chr 4:147,873,586...147,904,909
Ensembl chr 4:147,873,599...147,904,704
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO mRNA:increased expression:spinal cord, microglial cell RGD PMID:15067555 RGD:1641997 NCBI chr10:75,859,353...75,860,277
Ensembl chr10:75,859,353...75,860,240
JBrowse link
G Mir21a microRNA 21a exacerbates ISO RGD PMID:31102912 RGD:41410823 NCBI chr11:86,584,067...86,584,158
Ensembl chr11:86,584,067...86,584,158
JBrowse link
G Mir411 microRNA 411 ISO RGD PMID:29738767 RGD:13792580 NCBI chr12:109,710,175...109,710,256
Ensembl chr12:109,710,175...109,710,256
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:24436993 RGD:8657106 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:25763638 RGD:12791993 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mpo myeloperoxidase ISO protein:increased activity:spinal cord RGD PMID:22986158 RGD:6909148 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Mrc1 mannose receptor, C type 1 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chr 2:14,229,414...14,332,023
Ensembl chr 2:14,229,392...14,332,057
JBrowse link
G mt-Nd3 NADH dehydrogenase 3, mitochondrial ISO RGD PMID:20438613 RGD:5687694 NCBI chr MT:9,459...9,806
Ensembl chr MT:9,459...9,806
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:20678995 RGD:10040962 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D ISO mRNA:increased expression:spinal cord RGD PMID:18930143 RGD:2316199 NCBI chr 5:21,662,901...21,701,622
Ensembl chr 5:21,662,901...21,701,396
JBrowse link
G Ncam1 neural cell adhesion molecule 1 treatment ISO RGD PMID:28529158 RGD:40924632 NCBI chr 9:49,502,129...49,799,393
Ensembl chr 9:49,502,136...49,798,925
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 ISO protein:increased expression:spinal cord RGD PMID:14644473 RGD:2314450 NCBI chr 1:152,800,153...152,836,990
Ensembl chr 1:152,800,194...152,836,991
JBrowse link
G Nefh neurofilament, heavy polypeptide treatment ISO RGD PMID:18772508 PMID:32168135 RGD:9698443, RGD:27226888 NCBI chr11:4,938,754...4,948,064
Ensembl chr11:4,938,754...4,948,064
JBrowse link
G Nefl neurofilament, light polypeptide treatment ISO RGD PMID:18772508 RGD:9698443 NCBI chr14:68,083,863...68,089,095
Ensembl chr14:68,083,863...68,089,095
JBrowse link
G Nefm neurofilament, medium polypeptide treatment ISO RGD PMID:18772508 RGD:9698443 NCBI chr14:68,119,545...68,125,004
Ensembl chr14:68,082,590...68,124,846
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:24747453 RGD:10412730 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha treatment ISO RGD PMID:21134362 RGD:10413867 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Ngf nerve growth factor ISO RGD PMID:16915089 PMID:12499054 RGD:5144069, RGD:5144073 NCBI chr 3:102,469,919...102,521,013
Ensembl chr 3:102,469,919...102,521,013
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) treatment ISO mRNA:increased expression:spinal cord RGD PMID:11223160 PMID:23748892 RGD:5144100, RGD:10414079 NCBI chr11:95,568,818...95,587,698
Ensembl chr11:95,568,818...95,587,735
JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO RGD PMID:18687784 RGD:2311166 NCBI chr 5:101,659,184...101,664,711
Ensembl chr 5:101,658,139...101,664,996
JBrowse link
G Nlk nemo like kinase ISO protein:increased expression:grey matter: RGD PMID:24395089 RGD:12791278 NCBI chr11:78,567,168...78,697,595
Ensembl chr11:78,567,168...78,697,373
JBrowse link
G Nog noggin treatment IDA RGD PMID:18221366 RGD:10429192 NCBI chr11:89,300,638...89,302,559
Ensembl chr11:89,300,638...89,302,332
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO protein:increased expression:spinal cord RGD PMID:20633123 PMID:19291395 RGD:5131936, RGD:5132595 NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840
JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO mRNA:altered expression:thoracic aorta RGD PMID:17287083 RGD:4891407 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO RGD PMID:17287083 RGD:4891407 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO protein:increased expression:spinal cord (rat) RGD PMID:24747453 PMID:28881715 RGD:10412730, RGD:13434916 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Ntf3 neurotrophin 3 ISO RGD PMID:16022868 RGD:4891112 NCBI chr 6:126,101,412...126,166,772
Ensembl chr 6:126,101,412...126,166,910
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 ISO mRNA:decreased expression:spinal cord RGD PMID:18585435 RGD:2308892 NCBI chr 3:87,778,244...87,795,242
Ensembl chr 3:87,778,244...87,795,162
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 ISO RGD PMID:22027236 PMID:20597685 RGD:5684547, RGD:5684898 NCBI chr13:58,806,472...59,133,970
Ensembl chr13:58,806,569...59,133,970
JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 ISO mRNA:decreased expression:spinal cord RGD PMID:18585435 RGD:2308892 NCBI chr 7:78,179,986...78,581,034
Ensembl chr 7:78,175,959...78,738,012
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 treatment IMP
ISO
RGD PMID:28452182 PMID:22173726 RGD:40902836, RGD:40902844 NCBI chr16:91,225,550...91,228,677
Ensembl chr16:91,225,457...91,228,677
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 ISO CTD Direct Evidence: therapeutic CTD PMID:15258577 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15696051 PMID:21748659 RGD:10053608 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO RGD PMID:29665726 RGD:40886268 NCBI chr 1:94,038,305...94,052,553
Ensembl chr 1:94,038,305...94,052,553
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 ISO mRNA:increased expression:microglial cell RGD PMID:29665726 RGD:40886268 NCBI chr19:29,410,919...29,472,927
Ensembl chr19:29,410,919...29,471,161
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide IDA RGD PMID:21568693 RGD:6482306 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) IEP
ISO
protein:increased expression:spinal cord RGD PMID:21868473 PMID:19306380 RGD:6482718, RGD:6482721 NCBI chr 4:138,831,857...138,835,189
Ensembl chr 4:138,831,857...138,835,186
JBrowse link
G Pla2g6 phospholipase A2, group VI IEP protein:increased expression:spinal cord RGD PMID:21868473 RGD:6482718 NCBI chr15:79,286,228...79,328,385
Ensembl chr15:79,286,228...79,328,390
JBrowse link
G Plau plasminogen activator, urokinase IMP RGD PMID:21573723 RGD:6483797 NCBI chr14:20,836,662...20,843,388
Ensembl chr14:20,836,660...20,843,385
JBrowse link
G Plaur plasminogen activator, urokinase receptor IMP RGD PMID:21573723 RGD:6483797 NCBI chr 7:24,460,937...24,475,970
Ensembl chr 7:24,462,484...24,475,968
JBrowse link
G Pon1 paraoxonase 1 treatment ISO RGD PMID:12897486 RGD:8547682 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Ppard peroxisome proliferator activator receptor delta ISO RGD PMID:20058304 RGD:2324875 NCBI chr17:28,232,754...28,301,469
Ensembl chr17:28,232,700...28,301,474
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ISO RGD PMID:22208735 RGD:6484263 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO protein:increased expression:spinal cord, astrocyte, microglial cell RGD PMID:29033188 RGD:13514047 NCBI chr 5:122,154,967...122,175,273
Ensembl chr 5:122,158,278...122,175,273
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO mRNA:increased expression:spinal cord (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29793971 PMID:17578450 RGD:9999410 NCBI chr 7:45,522,917...45,526,268
Ensembl chr 7:45,522,916...45,526,268
JBrowse link
G Prkcg protein kinase C, gamma IEP protein:decreased expression:spinal cord (mouse) RGD PMID:10501452 RGD:28867228 NCBI chr 7:3,303,532...3,331,099
Ensembl chr 7:3,289,179...3,331,099
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia, macrophage RGD PMID:17184185 PMID:11063829 RGD:5688221, RGD:5688246 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18606213 RGD:5135219 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 treatment ISO RGD PMID:15016081 PMID:18065151 PMID:12895450 RGD:9589823, RGD:9590124, RGD:9590113 NCBI chr 6:22,875,315...23,052,916
Ensembl chr 6:22,875,502...23,052,916
JBrowse link
G Rara retinoic acid receptor, alpha ISO RGD PMID:16420438 RGD:2314291 NCBI chr11:98,927,800...98,974,942
Ensembl chr11:98,927,818...98,974,942
JBrowse link
G Rbmx RNA binding motif protein, X chromosome ISO RGD PMID:23180094 RGD:10053723 NCBI chr  X:57,383,348...57,393,046
Ensembl chr  X:57,383,530...57,393,036
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO RGD PMID:17918744 RGD:2298849 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rgma repulsive guidance molecule family member A treatment ISO RGD PMID:16585268 RGD:9850138 NCBI chr 7:73,375,520...73,419,899
Ensembl chr 7:73,375,509...73,419,899
JBrowse link
G Rpsa ribosomal protein SA ISO RGD PMID:19196078 RGD:11041651 NCBI chr 9:120,127,766...120,132,369
Ensembl chr 9:120,127,689...120,132,369
JBrowse link
G Scn3a sodium channel, voltage-gated, type III, alpha ISO RGD PMID:16109750 PMID:16718433 RGD:2317320 RGD:2317321 NCBI chr 2:65,457,118...65,567,591
Ensembl chr 2:65,457,118...65,567,627
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO RGD PMID:15792522 RGD:1599333 NCBI chr 1:160,978,583...161,002,543
Ensembl chr 1:160,978,585...161,005,863
JBrowse link
G Shh sonic hedgehog treatment ISO RGD PMID:24837681 RGD:12879409 NCBI chr 5:28,456,840...28,467,101
Ensembl chr 5:28,456,815...28,467,256
JBrowse link
G Siah1a siah E3 ubiquitin protein ligase 1A treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chr 8:86,720,454...86,746,006
Ensembl chr 8:86,724,007...86,745,934
JBrowse link
G Slc25a27 solute carrier family 25, member 27 IEP protein:increased expression:spinal cord RGD PMID:18534681 RGD:6482843 NCBI chr17:43,637,739...43,667,214
Ensembl chr17:43,641,891...43,667,214
JBrowse link
G Slit1 slit guidance ligand 1 IEP RGD PMID:16262652 RGD:2316136 NCBI chr19:41,597,824...41,747,275
Ensembl chr19:41,600,257...41,743,665
JBrowse link
G Slit2 slit guidance ligand 2 ISO mRNA, protein:increased expression:spinal cord RGD PMID:19783284 RGD:2316127 NCBI chr 5:47,981,291...48,307,735
Ensembl chr 5:47,983,138...48,307,733
JBrowse link
G Slit3 slit guidance ligand 3 IEP RGD PMID:16262652 RGD:2316136 NCBI chr11:35,121,456...35,708,507
Ensembl chr11:35,121,224...35,708,507
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO protein:increased expression:spinal cord RGD PMID:23595775 RGD:10412063 NCBI chr 5:144,876,495...144,965,899
Ensembl chr 5:144,876,495...144,965,847
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO RGD PMID:11723173 RGD:2298928 NCBI chr10:95,383,903...95,417,321
Ensembl chr10:95,385,362...95,417,180
JBrowse link
G Sod1 superoxide dismutase 1, soluble treatment ISO human protein in a rat model
CTD Direct Evidence: therapeutic
human gene in a rat model
CTD
RGD
PMID:17457363 PMID:18722523 PMID:16689664 RGD:8655939, RGD:8655990 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 IEP mRNA, protein:increased expression:spinal cord RGD PMID:23169458 RGD:8661675 NCBI chr 3:34,649,995...34,652,461
Ensembl chr 3:34,650,405...34,652,461
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein IMP RGD PMID:17611274 RGD:2300052 NCBI chr11:55,394,159...55,420,080
Ensembl chr11:55,394,500...55,423,183
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:15592854 RGD:6483848 NCBI chr 5:104,435,111...104,441,053
Ensembl chr 5:104,435,118...104,441,050
JBrowse link
G Sqstm1 sequestosome 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chr11:50,200,152...50,210,820
Ensembl chr11:50,199,366...50,210,827
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:18945947 RGD:2304258 NCBI chr 6:82,402,003...82,560,104
Ensembl chr 6:82,402,334...82,560,104
JBrowse link
G Tbp TATA box binding protein ISO protein:increased expression:spinal cord, astrocyte, microglial cell RGD PMID:24710803 RGD:9681729 NCBI chr17:15,499,888...15,517,427
Ensembl chr17:15,499,888...15,528,379
JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA, protein:increased expression:spinal cord RGD PMID:15798365 PMID:23793903 RGD:2291993, RGD:11038671 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RGD PMID:15145083 RGD:2302103 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO RGD PMID:15145083 RGD:2302103 NCBI chr 1:186,622,787...186,709,697
Ensembl chr 1:186,622,792...186,705,989
JBrowse link
G Thbd thrombomodulin ISO RGD PMID:15307903 RGD:1580060 NCBI chr 2:148,404,471...148,408,188
Ensembl chr 2:148,404,466...148,408,188
JBrowse link
G Thbs1 thrombospondin 1 ISO protein:increased expression:spinal cord RGD PMID:19719963 RGD:2317939 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133
JBrowse link
G Tlr1 toll-like receptor 1 treatment IEP
IDA
mRNA:increased expression:spinal cord (mouse) RGD PMID:21970496 PMID:21970496 RGD:7246886, RGD:7246886 NCBI chr 5:64,924,680...64,933,600
Ensembl chr 5:64,924,679...64,933,563
JBrowse link
G Tlr4 toll-like receptor 4 severity IMP RGD PMID:25990044 RGD:14700556 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tnc tenascin C ISO mRNA:increased expression:spinal cord RGD PMID:11085900 RGD:4889619 NCBI chr 4:63,959,785...64,047,015
Ensembl chr 4:63,959,785...64,047,015
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:20633123 RGD:5131936 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO protein:increased expression:cerebrospinal fluid RGD PMID:16083358 RGD:1624185 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Trp53 transformation related protein 53 ISO protein:increased expression:spinal cord RGD PMID:23595775 RGD:10412063 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 ISO mRNA,protein:increased expression:urinary bladder, dorsal root ganglion: RGD PMID:21367919 RGD:10043365 NCBI chr 1:14,872,644...14,918,862
Ensembl chr 1:14,872,648...14,918,862
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 treatment ISO RGD PMID:19169264 PMID:25763638 RGD:10003030, RGD:12791993 NCBI chr 7:45,303,155...45,334,071
Ensembl chr 7:45,302,632...45,333,780
JBrowse link
G Tug1 taurine upregulated gene 1 treatment ISO RGD PMID:30287503 RGD:38549580 NCBI chr11:3,639,785...3,648,814
Ensembl chr11:3,639,785...3,649,673
JBrowse link
G Ulk1 unc-51 like kinase 1 ISO protein:increased expression:neuron, axon RGD PMID:25040536 RGD:11553820 NCBI chr 5:110,784,489...110,810,120
Ensembl chr 5:110,784,488...110,810,097
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21092735 PMID:21092735 RGD:5148013 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO RGD PMID:20125055 RGD:2325181 NCBI chr 6:113,623,994...113,631,634
Ensembl chr 6:113,623,959...113,631,633
JBrowse link
G Vim vimentin IMP
ISO
protein:increased expression:spinal cord RGD PMID:10225952 PMID:21250919 RGD:6480471, RGD:6480511 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826
JBrowse link
G Vwf Von Willebrand factor ISO RGD PMID:25771801 RGD:13673888 NCBI chr 6:125,552,948...125,686,679
Ensembl chr 6:125,546,774...125,686,679
JBrowse link
G Xbp1 X-box binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
G Xdh xanthine dehydrogenase ISO protein:increased expression:spinal cord RGD PMID:1649310 RGD:13209021 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
G Xylt1 xylosyltransferase 1 ISO RGD PMID:18765417 RGD:2313145 NCBI chr 7:117,380,979...117,667,630
Ensembl chr 7:117,380,979...117,673,580
JBrowse link
Spinal Cord Compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 ISO mRNA, protein:increased expression, increased activity:spinal cord (rat) RGD PMID:22425718 RGD:10449098 NCBI chr 2:26,973,361...27,009,625
Ensembl chr 2:26,973,416...27,009,628
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 ISO mRNA, protein:increased expression:dorsal root ganglion (rat) RGD PMID:23613963 RGD:14390159 NCBI chr 9:108,053,159...108,055,701
Ensembl chr 9:108,053,159...108,055,701
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO mRNA, protein:increased expression:liver, serum (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15135227 PMID:15855648 RGD:11526154 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Cd163 CD163 antigen disease_progression ISO protein:increased expression:gray matter of spinal cord, white matter of spinal cord (rat) RGD PMID:23775900 RGD:149735576 NCBI chr 6:124,304,636...124,330,529
Ensembl chr 6:124,304,656...124,330,527
JBrowse link
G Egr1 early growth response 1 ISO protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:20675054 RGD:5131876 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Elane elastase, neutrophil expressed treatment ISO RGD PMID:9675307 RGD:10450552 NCBI chr10:79,886,312...79,888,216
Ensembl chr10:79,886,247...79,888,215
JBrowse link
G Epo erythropoietin ISO protein:increased expression:neuron, endothelium, glia: RGD PMID:15792521 RGD:11041719 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G Epor erythropoietin receptor ISO protein:increased expression:neuron, endothelium, glia: RGD PMID:15792521 RGD:11041719 NCBI chr 9:21,958,897...21,963,576
Ensembl chr 9:21,958,897...21,963,506
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO
IMP
human protein in a rat model
protein:increased expression:spinal cord:
RGD PMID:16689665 PMID:21490053 PMID:16202410 RGD:1582444, RGD:12904017, RGD:8663485 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) treatment ISO
IMP
protein:increased expression:spinal cord: RGD PMID:21490053 PMID:21490053 RGD:12904017, RGD:12904017 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO protein:increased expression:spinal cord RGD PMID:17244329 RGD:8655633 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108
JBrowse link
G Fis1 fission, mitochondrial 1 treatment ISO RGD PMID:25595990 RGD:12437079 NCBI chr 5:136,953,275...136,966,234
Ensembl chr 5:136,953,275...136,966,234
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 ISO protein:decreased expression:spinal cord, thoracic vertebrae (rat) RGD PMID:20399821 RGD:2326108 NCBI chr13:119,690,351...119,708,260
Ensembl chr13:119,690,379...119,708,260
JBrowse link
G Hspa4 heat shock protein 4 IEP protein:increased expression:spinal cord (mouse) RGD PMID:21787762 RGD:6218959 NCBI chr11:53,259,814...53,300,479
Ensembl chr11:53,259,814...53,300,457
JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:cerebrospinal fluid, serum RGD PMID:30327453 RGD:14975119 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G L1cam L1 cell adhesion molecule IMP RGD PMID:21671795 RGD:6483029 NCBI chr  X:73,853,778...73,880,838
Ensembl chr  X:73,853,778...73,896,105
JBrowse link
G Mt2 metallothionein 2 IEP mRNA:increased expression:spinal cord (mouse) RGD PMID:15592854 RGD:6483848 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO RGD PMID:29323048 RGD:13504709 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:12227717 NCBI chr 8:22,757,722...22,782,848
Ensembl chr 8:22,757,727...22,782,844
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15135227 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO protein:increased expression:spinal cord (rat) RGD PMID:21224756 RGD:5130917 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO human protein in rat model
protein:increased expression:spinal cord (rat)
RGD PMID:21224756 PMID:21224756 RGD:5130917, RGD:5130917 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14541
    Wounds and Injuries 877
      Spinal Cord Injuries 268
        Autonomic Dysreflexia 0
        Central Cord Syndrome 0
        Spinal Cord Compression 22
Path 2
Term Annotations click to browse term
  disease 14541
    disease of anatomical entity 14141
      nervous system disease 11644
        central nervous system disease 10156
          spinal cord disease 1619
            Spinal Cord Injuries 268
              Autonomic Dysreflexia 0
              Central Cord Syndrome 0
              Spinal Cord Compression 22
paths to the root