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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Spinal Cord Injuries
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Accession:DOID:9000039 term browser browse the term
Definition:Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Synonyms:exact_synonym: Post Traumatic Myelopathy;   Post-Traumatic Myelopathies;   Spinal Cord Contusion;   Spinal Cord Contusions;   Spinal Cord Injury;   Spinal Cord Laceration;   Spinal Cord Lacerations;   Spinal Cord Transection;   Spinal Cord Transections;   Spinal Cord Trauma;   Spinal Cord Traumas;   Traumatic Myelopathies;   Traumatic Myelopathy
 narrow_synonym: acute spinal cord injury
 primary_id: MESH:D013119;   RDO:0006597
For additional species annotation, visit the Alliance of Genome Resources.


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Spinal Cord Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment ISO mRNA:increased expression:spinal cord RGD PMID:20410530 PMID:25763638 RGD:12790978 RGD:12791993 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053
JBrowse link
G Acan aggrecan ISO protein:altered expression:spinal cord (rat) RGD PMID:14769391 RGD:2315837 NCBI chrNW_004955416:16,125,536...16,186,046 JBrowse link
G Adarb1 adenosine deaminase RNA specific B1 ISO RGD PMID:20456005 RGD:10755338 NCBI chrNW_004955407:41,886,286...41,962,846
Ensembl chrNW_004955407:41,886,286...41,962,897
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO protein:altered expression:spinal cord,dorsal root ganglion, urinary bladder RGD PMID:15698618 PMID:15913892 RGD:2325306 RGD:2325309 NCBI chrNW_004955402:9,091,927...9,099,803
Ensembl chrNW_004955402:9,091,725...9,099,803
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16213239 RGD:5686719 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adora1 adenosine A1 receptor ISO protein:decreased expression:spinal cord RGD PMID:17853654 PMID:18289533 PMID:20065990 RGD:4890369 RGD:5129094 RGD:5129096 NCBI chrNW_004955406:39,148,811...39,183,577
Ensembl chrNW_004955406:39,149,689...39,187,688
JBrowse link
G Adora2a adenosine A2a receptor ISO RGD PMID:17559837 RGD:4890378 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505
JBrowse link
G Adra1a adrenoceptor alpha 1A ISO mRNA:increased expression:aorta RGD PMID:16524515 RGD:5688371 NCBI chrNW_004955403:49,394,173...49,485,881
Ensembl chrNW_004955403:49,399,127...49,485,934
JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO protein:increased expression:spinal cord (rat) RGD PMID:20195207 RGD:2325645 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Aif1 allograft inflammatory factor 1 ISO protein:altered expression:spinal cord dorsal horn (rat) RGD PMID:17158026 RGD:2313037 NCBI chrNW_004955437:157,509...158,919 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:20678995 RGD:10040962 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Akt1s1 AKT1 substrate 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17457363 NCBI chrNW_004955559:1,055,998...1,063,192
Ensembl chrNW_004955559:1,056,357...1,063,192
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chrNW_004955422:1,455,392...1,644,368
Ensembl chrNW_004955422:1,455,380...1,644,452
JBrowse link
G Ankrd1 ankyrin repeat domain 1 ISO mRNA:increased expression:spinal cord, dorsal root ganglion, neuron RGD PMID:17610582 RGD:5133279 NCBI chrNW_004955425:2,258,554...2,267,699
Ensembl chrNW_004955425:2,258,392...2,267,878
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B ISO RGD PMID:25034417 RGD:10401137 NCBI chrNW_004955419:27,471,539...27,553,078
Ensembl chrNW_004955419:27,471,930...27,488,065
JBrowse link
G Anxa1 annexin A1 treatment ISO mRNA,protein:increased expression:neuron,glial cell RGD PMID:15248295 PMID:17917587 RGD:10053688 RGD:2306891 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Anxa2 annexin A2 ISO mRNA,protein:increased expression:neuron,glial cell RGD PMID:15248295 RGD:10053688 NCBI chrNW_004955450:14,545,586...14,574,161
Ensembl chrNW_004955450:14,512,381...14,574,696
JBrowse link
G Anxa5 annexin A5 ISO mRNA,protein:increased expression:neuron,glial cell RGD PMID:15248295 RGD:10053688 NCBI chrNW_004955428:18,873,782...18,907,955
Ensembl chrNW_004955428:18,873,782...18,907,955
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO RGD PMID:21748659 RGD:10053608 NCBI chrNW_004955405:34,619,780...34,693,616
Ensembl chrNW_004955405:34,623,267...34,693,677
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO mRNA:increased expression:spinal cord RGD PMID:18637713 RGD:2315670 NCBI chrNW_004955550:1,273,170...1,275,843
Ensembl chrNW_004955550:1,273,284...1,279,743
JBrowse link
G Apoe apolipoprotein E ISO DNA:polymorphism:exon: RGD PMID:18581664 PMID:30036659 RGD:13703128 RGD:7771551 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:spinal cord, neuron, astrocyte
RGD
CTD
PMID:18248364 PMID:21092735 RGD:2307072 RGD:5148013 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
JBrowse link
G Aqp4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:20517941 PMID:21092735 PMID:21280976 RGD:5148013 RGD:5148027 RGD:5148035 NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
JBrowse link
G Atf4 activating transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218
JBrowse link
G Atg5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:axon
CTD
RGD
PMID:25040536 PMID:29793971 RGD:11553820 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827
JBrowse link
G Atg7 autophagy related 7 ISO protein:increased expression:axon RGD PMID:25040536 RGD:11553820 NCBI chrNW_004955429:14,076,976...14,301,034
Ensembl chrNW_004955429:14,076,960...14,304,236
JBrowse link
G Atm ATM serine/threonine kinase ISO protein:increased expression:spinal cord RGD PMID:21748659 RGD:10053608 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO protein:decreased expression:tail, skeletal muscle RGD PMID:21930674 RGD:13782071 NCBI chrNW_004955493:6,559,995...6,578,461
Ensembl chrNW_004955493:6,559,995...6,578,461
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO protein:decreased expression:tail, skeletal muscle RGD PMID:21930674 RGD:13782071 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754
JBrowse link
G Bambi BMP and activin membrane bound inhibitor ISO mRNA,protein:decreased expression:spinal cord: RGD PMID:28035406 RGD:14390163 NCBI chrNW_004955429:21,024,396...21,025,890
Ensembl chrNW_004955429:21,024,374...21,025,890
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
JBrowse link
G Bcan brevican treatment ISO RGD PMID:15016081 RGD:9589823 NCBI chrNW_004955545:2,723,780...2,739,334
Ensembl chrNW_004955545:2,723,780...2,739,450
JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Bdnf brain derived neurotrophic factor treatment ISO RGD PMID:16022868 PMID:19203225 PMID:24551172 RGD:10059354 RGD:4891066 RGD:4891112 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Becn1 beclin 1 treatment ISO protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21806471 PMID:23852559 PMID:24559459 PMID:29793971 RGD:11561918 RGD:11561922 RGD:6483100 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO RGD PMID:23770801 RGD:9068404 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181
JBrowse link
G Bmp4 bone morphogenetic protein 4 treatment ISO RGD PMID:18803859 PMID:23770801 RGD:9068404 RGD:9068437 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Bnip3 BCL2 interacting protein 3 ISO protein:increased expression:spinal cord RGD PMID:23637053 RGD:11564330 NCBI chrNW_004955477:9,621,812...9,630,406
Ensembl chrNW_004955477:9,621,812...9,638,099
JBrowse link
G Bnip3l BCL2 interacting protein 3 like ISO protein:increased expression:spinal cord RGD PMID:23637053 RGD:11564330 NCBI chrNW_004955403:49,122,408...49,144,162
Ensembl chrNW_004955403:49,122,408...49,144,998
JBrowse link
G Brca2 BRCA2 DNA repair associated ISO mRNA,protein:increased expression:spinal cord: RGD PMID:21748659 RGD:10053608 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432
JBrowse link
G C1qb complement C1q B chain ISO mRNA:increased expression RGD PMID:16345062 RGD:1599510 NCBI chrNW_004955452:2,765,844...2,771,695
Ensembl chrNW_004955452:2,769,752...2,772,534
JBrowse link
G Capn1 calpain 1 treatment ISO RGD PMID:23102374 RGD:13792496 NCBI chrNW_004955422:20,006,448...20,026,984
Ensembl chrNW_004955422:20,004,426...20,025,708
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta ISO protein:decreased expression:spinal cord RGD PMID:20141154 RGD:9685028 NCBI chrNW_004955452:34,454...168,514
Ensembl chrNW_004955452:30,589...169,693
JBrowse link
G Casp3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:14588118 PMID:18378144 PMID:21748659 PMID:27256506 PMID:27339639 RGD:10053608 RGD:13782345 RGD:13792677 RGD:2293322 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:21748659 PMID:27339639 RGD:10053608 RGD:13782345 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Cav1 caveolin 1 ISO protein:increased phosphorylation:spinal cord RGD PMID:17275798 RGD:2289124 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:spinal cord segment (mouse) RGD PMID:20478301 RGD:4889905 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
JBrowse link
G Ccnd3 cyclin D3 ISO protein:increased expression:spinal cord RGD PMID:18008145 RGD:2316019 NCBI chrNW_004955437:8,266,523...8,273,855
Ensembl chrNW_004955437:8,268,118...8,273,855
JBrowse link
G Ccne1 cyclin E1 ISO protein:increased expression:spinal cord RGD PMID:16759516 RGD:2289281 NCBI chrNW_004955468:7,803,610...7,814,872
Ensembl chrNW_004955468:7,803,346...7,814,872
JBrowse link
G Ccnh cyclin H ISO mRNA, protein:increased expression:spinal cord RGD PMID:21710280 RGD:9590263 NCBI chrNW_004955418:23,790,398...23,807,509
Ensembl chrNW_004955418:23,790,001...23,807,702
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:increased expression:spinal cord RGD PMID:18338959 RGD:4144888 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Cd274 CD274 molecule ISO mRNA:increased expression:microglial cell RGD PMID:29665726 RGD:40886268 NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904
JBrowse link
G Cdc42 cell division cycle 42 ISO mRNA:increased expression:spinal cord RGD PMID:15736231 RGD:5688276 NCBI chrNW_004955452:2,255,940...2,299,042
Ensembl chrNW_004955452:2,255,117...2,299,042
JBrowse link
G Cdk1 cyclin dependent kinase 1 ISO protein:increased expression:spinal cord dura mater (rat) RGD PMID:19672039 RGD:2316488 NCBI chrNW_004955425:14,210,681...14,226,474
Ensembl chrNW_004955425:14,210,680...14,226,474
JBrowse link
G Cdk19 cyclin dependent kinase 19 ISO mRNA, protein:increased expression:spinal cord RGD PMID:18008145 RGD:2316019 NCBI chrNW_004955411:35,312,722...35,411,951
Ensembl chrNW_004955411:35,312,722...35,412,246
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO protein:decreased expression, altered localization:spinal cord, neuron, microglial cell RGD PMID:18319192 RGD:2293615 NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542
JBrowse link
G Chl1 cell adhesion molecule L1 like ISO protein:increased expression:spinal cord (rat) RGD PMID:21337374 RGD:6483045 NCBI chrNW_004955421:12,763,432...12,957,852
Ensembl chrNW_004955421:12,763,287...12,958,065
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:18930143 RGD:2316199 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO RGD PMID:18930143 RGD:2316199 NCBI chrNW_004955452:3,763,742...3,795,069
Ensembl chrNW_004955452:3,763,742...3,795,069
JBrowse link
G Cr2 complement C3d receptor 2 ISO protein:increased expression:cerebrospinal fluid RGD PMID:26502875 RGD:11343913 NCBI chrNW_004955406:42,877,041...42,910,970
Ensembl chrNW_004955406:42,876,966...42,911,564
JBrowse link
G Crh corticotropin releasing hormone ISO protein:altered expression:spinal cord (rat) RGD PMID:20458328 RGD:5490964 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Csf2 colony stimulating factor 2 treatment ISO RGD PMID:15658127 RGD:10449531 NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:21953623 RGD:10450511 NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 ISO RGD PMID:19604403 PMID:22042562 PMID:22243800 RGD:5686844 RGD:5686848 RGD:5686859 NCBI chrNW_004955450:2,631,310...2,663,118
Ensembl chrNW_004955450:2,631,327...2,662,269
JBrowse link
G Ctss cathepsin S ISO RGD PMID:16344894 RGD:2303423 NCBI chrNW_004955413:99,279...124,793
Ensembl chrNW_004955413:99,159...124,042
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO RGD PMID:19170890 RGD:2311365 NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927
JBrowse link
G Dab2 DAB adaptor protein 2 ISO protein:increased expression:spinal cord RGD PMID:17317100 RGD:7243246 NCBI chrNW_004955426:23,852,752...23,883,030 JBrowse link
G Dcc DCC netrin 1 receptor ISO RGD PMID:16998900 RGD:2314373 NCBI chrNW_004955402:37,123,112...38,218,876
Ensembl chrNW_004955402:37,123,795...38,218,472
JBrowse link
G Ddit3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chrNW_004955458:5,232,979...5,238,513
Ensembl chrNW_004955458:5,232,979...5,238,513
JBrowse link
G Dusp1 dual specificity phosphatase 1 treatment ISO protein:decreased expression:spinal cord RGD PMID:18630599 PMID:19383246 RGD:7771572 RGD:7771580 NCBI chrNW_004955408:25,481,294...25,484,381
Ensembl chrNW_004955408:25,481,294...25,484,381
JBrowse link
G Efnb2 ephrin B2 ISO mRNA,protein:increased expression:fibroblast, astrocyte
protein:increased phosporylation:spinal cord
RGD PMID:12944508 PMID:33794069 RGD:127285659 RGD:127285804 NCBI chrNW_004955404:5,000,906...5,030,068
Ensembl chrNW_004955404:5,000,906...5,030,126
JBrowse link
G Egfr epidermal growth factor receptor ISO protein:increased phosphorylation:spinal cord, astrocyte (rat) RGD PMID:20869112 PMID:21402118 RGD:5131454 RGD:5131525 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Eif5a eukaryotic translation initiation factor 5A ISO mRNA, protein:increased expression:gastrocnemius RGD PMID:23238062 RGD:10395360 NCBI chrNW_004955467:9,603,800...9,608,490 JBrowse link
G Endog endonuclease G ISO RGD PMID:16689664 RGD:8655990 NCBI chrNW_004955570:1,200,461...1,203,566
Ensembl chrNW_004955570:1,200,996...1,203,566
JBrowse link
G Eno2 enolase 2 ISO protein:increased expression:serum, cerebrospinal fluid RGD PMID:18343116 RGD:2293743 NCBI chrNW_004955413:4,498,625...4,506,769
Ensembl chrNW_004955413:4,498,625...4,506,769
JBrowse link
G Ensa endosulfine alpha ISO mRNA:decreased expression:spinal cord RGD PMID:16344894 RGD:2303423 NCBI chrNW_004955413:197,239...204,867
Ensembl chrNW_004955413:197,242...204,867
JBrowse link
G Epha3 EPH receptor A3 ISO RGD PMID:16083359 RGD:2301766 NCBI chrNW_004955407:4,135,671...4,500,900
Ensembl chrNW_004955407:4,138,362...4,500,688
JBrowse link
G Epha4 EPH receptor A4 ISO RGD PMID:17418490 PMID:17970742 PMID:21931787 RGD:5688750 RGD:5688764 RGD:5688782 NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199
JBrowse link
G Epha7 EPH receptor A7 ISO mRNA:increased expression:spinal cord RGD PMID:16983667 RGD:2301957 NCBI chrNW_004955411:19,652,146...19,815,418
Ensembl chrNW_004955411:19,650,515...19,815,512
JBrowse link
G Ephb2 EPH receptor B2 ameliorates ISO RGD PMID:12944508 PMID:33794069 RGD:127285659 RGD:127285804 NCBI chrNW_004955452:2,844,713...2,986,790
Ensembl chrNW_004955452:2,844,713...2,980,445
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:22196867 RGD:10401074 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO mRNA, protein:increased expression:spinal cord RGD PMID:11797086 RGD:2289967 NCBI chrNW_004955458:3,683,126...3,701,752
Ensembl chrNW_004955458:3,683,126...3,702,978
JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:25105782 RGD:10045844 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:25105782 RGD:10045844 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:16344894 RGD:2303423 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Fadd Fas associated via death domain treatment ISO RGD PMID:23574812 RGD:11344882 NCBI chrNW_004955422:16,026,323...16,035,808
Ensembl chrNW_004955422:16,031,280...16,036,281
JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:cervical spinal cord RGD PMID:17518537 PMID:17703359 PMID:29738767 RGD:13792580 RGD:2290176 RGD:2290177 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO Human FGF1 used in rat model of spinal cord injury RGD PMID:8662542 PMID:18482974 PMID:20488178 PMID:21663406 RGD:2317692 RGD:5509875 RGD:5509876 RGD:5509877 NCBI chrNW_004955415:11,151,330...11,245,554
Ensembl chrNW_004955415:11,151,266...11,247,344
JBrowse link
G Fgf2 fibroblast growth factor 2 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
JBrowse link
G Fis1 fission, mitochondrial 1 treatment ISO RGD PMID:26079325 RGD:12437066 NCBI chrNW_004955456:16,057,158...16,060,623
Ensembl chrNW_004955456:16,038,221...16,060,623
JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO mRNA:increased expression:spinal cord, astrocyte, macrophage RGD PMID:17409380 RGD:5684414 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:20347014 RGD:7205459 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Foxo3 forkhead box O3 ISO protein:decreased expression:spinal cord,neuron, astrocyte: RGD PMID:22930444 RGD:10402202 NCBI chrNW_004955411:33,655,958...33,770,829
Ensembl chrNW_004955411:33,655,958...33,770,829
JBrowse link
G Foxp3 forkhead box P3 treatment ISO RGD PMID:30287503 RGD:38549580 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
JBrowse link
G Gap43 growth associated protein 43 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chrNW_004955427:15,696,549...15,791,279
Ensembl chrNW_004955427:15,695,963...15,791,327
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO RGD PMID:22342994 RGD:5688774 NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324
JBrowse link
G Gfap glial fibrillary acidic protein treatment ISO protein:increased expression:spinal cord RGD PMID:10225952 PMID:21250919 PMID:24968269 RGD:40924652 RGD:6480471 RGD:6480511 NCBI chrNW_004955451:17,695,835...17,703,894
Ensembl chrNW_004955451:17,695,835...17,703,268
JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:25261791 RGD:12907564 NCBI chrNW_004955420:2,483,173...2,486,414
Ensembl chrNW_004955420:2,478,877...2,487,215
JBrowse link
G Gja1 gap junction protein alpha 1 treatment ISO RGD PMID:23403365 PMID:24183749 RGD:8662431 RGD:8662460 NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095
JBrowse link
G Gjc2 gap junction protein gamma 2 treatment ISO RGD PMID:26415641 RGD:13208513 NCBI chrNW_004955581:291,537...294,752 JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO protein:increased expression:spinal cord (rat) RGD PMID:27150525 RGD:13506243 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO RGD PMID:22975889 RGD:8552988 NCBI chrNW_004955460:8,790,798...8,794,902
Ensembl chrNW_004955460:8,790,798...8,794,902
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO protein:increased expression:spinal cord, neuron, microglial cell (rat) RGD PMID:23359120 RGD:13792782 NCBI chrNW_004955408:29,665,534...29,684,225
Ensembl chrNW_004955408:29,665,260...29,684,207
JBrowse link
G Grn granulin precursor ISO mRNA, protein:increased expression:spinal cord: RGD PMID:19946692 RGD:5509603 NCBI chrNW_004955451:17,368,600...17,371,981
Ensembl chrNW_004955451:17,368,428...17,372,377
JBrowse link
G Hgf hepatocyte growth factor treatment ISO mRNA,protein:increased expression:spinal cord: RGD PMID:17549731 PMID:22140459 RGD:2317487 RGD:8548666 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:spinal cord
CTD
RGD
PMID:21092735 RGD:5148013 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hmgb1 high mobility group box 1 ISO mRNA:increased expression:spinal cord RGD PMID:20195207 RGD:2325645 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:23943397 RGD:10766443 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:16671478 RGD:1626425 NCBI chrNW_004955528:1,819,247...1,826,707
Ensembl chrNW_004955528:1,819,247...1,826,707
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO protein:decreased expression:spinal cord (rat) RGD PMID:24499940 RGD:10445836 NCBI chrNW_004955437:9,872,649...9,878,459
Ensembl chrNW_004955437:9,873,908...9,878,459
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO mRNA: increased expression RGD PMID:21933012 RGD:5685666 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 treatment ISO mRNA,protein:increased expression:spinal cord: RGD PMID:12098653 PMID:30287503 RGD:10402749 RGD:38549580 NCBI chrNW_004955844:8,094...9,565
Ensembl chrNW_004955844:7,790...10,004
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:8627308 RGD:11522712 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO mRNA:increased expression:spinal cord (rat) RGD PMID:11746449 RGD:9686138 NCBI chrNW_004955422:29,337,969...29,339,178
Ensembl chrNW_004955422:29,337,757...29,339,178
JBrowse link
G Id2 inhibitor of DNA binding 2 ISO mRNA:increased expression:spinal cord (rat) RGD PMID:11746449 RGD:9686138 NCBI chrNW_004955487:878,326...880,783
Ensembl chrNW_004955487:878,326...880,783
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein ISO mRNA:increased expression:spinal cord (rat) RGD PMID:11746449 RGD:9686138 NCBI chrNW_004955452:3,537,352...3,538,921
Ensembl chrNW_004955452:3,537,021...3,560,954
JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:29691718 RGD:14975124 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:18367607 PMID:23140983 RGD:2315889 RGD:8655974 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
JBrowse link
G Il1b interleukin 1 beta treatment ISO mRNA, protein:increased expression:spinal cord RGD PMID:16038625 PMID:23209732 PMID:29691718 RGD:14975124 RGD:1626673 RGD:7175523 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO mRNA,protein:increased expression:spinal cord RGD PMID:16456668 RGD:7207035 NCBI chrNW_004955470:7,685,498...7,703,374 JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:serum (human) RGD PMID:16038625 PMID:17964877 RGD:1626673 RGD:6907102 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il4 interleukin 4 ISO RGD PMID:20623539 RGD:5128562 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor ISO mRNA:increased expression:spinal cord RGD PMID:20623539 RGD:5128562 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:27085942 PMID:29691718 RGD:11062150 RGD:14975124 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Irf1 interferon regulatory factor 1 ISO RGD PMID:11723173 RGD:2298928 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 severity ISO protein:decreased expression:cerebrospinal fluid RGD PMID:21559420 RGD:40907059 NCBI chrNW_004955430:2,772,064...2,787,912
Ensembl chrNW_004955430:2,770,373...2,789,131
JBrowse link
G Jak2 Janus kinase 2 treatment ISO RGD PMID:23274522 RGD:10411896 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO protein:increased phosphorylation:neuron RGD PMID:21132399 RGD:4889994 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Kcnj10 potassium inwardly rectifying channel subfamily J member 10 ISO protein:decreased expression:spinal cord RGD PMID:20375134 RGD:8662905 NCBI chrNW_004955468:11,828,525...11,860,365
Ensembl chrNW_004955468:11,828,525...11,860,365
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 treatment ISO RGD PMID:22425721 RGD:9831183 NCBI chrNW_004955406:2,793,493...2,975,322
Ensembl chrNW_004955406:2,791,803...2,975,322
JBrowse link
G Kdm6b lysine demethylase 6B ISO mRNA:increased expression:spinal cord (rat) RGD PMID:22578249 RGD:9587821 NCBI chrNW_004955467:9,085,239...9,106,658
Ensembl chrNW_004955467:9,086,204...9,094,404
JBrowse link
G Kdr kinase insert domain receptor ISO mRNA:increased expression:spinal cord, astrocyte, macrophage RGD PMID:17409380 RGD:5684414 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Kif3b kinesin family member 3B ISO protein:increased expression:spinal cord RGD PMID:23093447 RGD:11049594 NCBI chrNW_004955422:28,738,567...28,779,584
Ensembl chrNW_004955422:28,738,572...28,780,112
JBrowse link
G Klk6 kallikrein related peptidase 6 ISO protein:increased expression:spinal cord RGD PMID:16987227 RGD:2314866 NCBI chrNW_004955558:1,501,806...1,509,461
Ensembl chrNW_004955558:1,502,881...1,509,558
JBrowse link
G Kmo kynurenine 3-monooxygenase ISO mRNA,protein:increased expression:spinal cord: RGD PMID:26524415 RGD:13703043 NCBI chrNW_004955406:10,496,102...10,527,181
Ensembl chrNW_004955406:10,493,379...10,527,201
JBrowse link
G Lep leptin ISO RGD PMID:19777863 RGD:5128780 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G LOC102004641 cytochrome b-245 light chain ISO mRNA:increased expression:spinal cord RGD PMID:16345062 RGD:1599510 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118
JBrowse link
G LOC102012042 cytochrome b-245 heavy chain ISO mRNA,protein:increased expression:microglia: RGD PMID:20679217 RGD:11040629 NCBI chrNW_004955587:781,533...818,149
Ensembl chrNW_004955587:781,388...819,912
JBrowse link
G Lrp1 LDL receptor related protein 1 treatment ISO RGD PMID:23867460 RGD:13800520 NCBI chrNW_004955458:4,861,431...4,941,939
Ensembl chrNW_004955458:4,861,431...4,941,146
JBrowse link
G Lrp5 LDL receptor related protein 5 treatment ISO RGD PMID:24090150 RGD:12798566 NCBI chrNW_004955422:17,394,371...17,475,244
Ensembl chrNW_004955422:17,394,371...17,505,763
JBrowse link
G Lum lumican ISO protein:increased expression:spinal cord RGD PMID:18482974 RGD:2317692 NCBI chrNW_004955405:28,299,966...28,307,982
Ensembl chrNW_004955405:28,298,988...28,308,054
JBrowse link
G Map1b microtubule associated protein 1B ISO protein:increased phosphorylation:spinal cord, neuron RGD PMID:17880387 RGD:2304007 NCBI chrNW_004955575:914,607...1,020,971
Ensembl chrNW_004955575:913,723...1,021,028
JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha treatment ISO protein:increased expression:spinal cord RGD PMID:23637053 PMID:23852559 PMID:24559459 RGD:11561918 RGD:11561922 RGD:11564330 NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884
JBrowse link
G Map1lc3b microtubule associated protein 1 light chain 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chrNW_004955541:1,852,388...1,868,194 JBrowse link
G Map2 microtubule associated protein 2 ISO RGD PMID:21704982 RGD:6483323 NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO protein:increased expression:white matter and grey matter: RGD PMID:10331432 RGD:10412645 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808
JBrowse link
G Mapt microtubule associated protein tau treatment ISO RGD PMID:22052241 RGD:8158113 NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO protein:increased expression:spinal cord RGD PMID:23595775 RGD:10412063 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO mRNA, protein:increased expression:spinal cord (rat) RGD PMID:17549731 RGD:2317487 NCBI chrNW_004955432:22,440,671...22,519,592
Ensembl chrNW_004955432:22,440,637...22,517,647
JBrowse link
G Mfn1 mitofusin 1 treatment ISO protein:altered expression:spinal cord, mitochondrion (rat) RGD PMID:26079325 PMID:26981103 RGD:12437066 RGD:12910837 NCBI chrNW_004955420:8,541,547...8,596,494
Ensembl chrNW_004955420:8,541,936...8,594,437
JBrowse link
G Mfn2 mitofusin 2 treatment ISO protein:increased expression:spinal cord (rat) RGD PMID:26079325 PMID:28404953 RGD:12437066 RGD:12910735 NCBI chrNW_004955486:1,937,873...1,962,577
Ensembl chrNW_004955486:1,937,802...1,962,772
JBrowse link
G Mif macrophage migration inhibitory factor ISO mRNA:increased expression:spinal cord, microglial cell RGD PMID:15067555 RGD:1641997 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:24436993 RGD:8657106 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:25763638 RGD:12791993 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Mpo myeloperoxidase ISO protein:increased activity:spinal cord RGD PMID:22986158 RGD:6909148 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Mrc1 mannose receptor C-type 1 treatment ISO RGD PMID:24968269 RGD:40924652 NCBI chrNW_004955429:10,139,398...10,232,541
Ensembl chrNW_004955429:10,139,355...10,232,600
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:20678995 RGD:10040962 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D ISO mRNA:increased expression:spinal cord RGD PMID:18930143 RGD:2316199 NCBI chrNW_004955410:8,217,684...8,233,302
Ensembl chrNW_004955410:8,220,400...8,247,486
JBrowse link
G Ncam1 neural cell adhesion molecule 1 treatment ISO RGD PMID:28529158 RGD:40924632 NCBI chrNW_004955412:14,630,109...14,923,847
Ensembl chrNW_004955412:14,630,443...14,923,926
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 ISO protein:increased expression:spinal cord RGD PMID:14644473 RGD:2314450 NCBI chrNW_004955406:22,355,717...22,384,746
Ensembl chrNW_004955406:22,355,724...22,384,864
JBrowse link
G Nefh neurofilament heavy chain treatment ISO RGD PMID:18772508 PMID:32168135 RGD:27226888 RGD:9698443 NCBI chrNW_004955455:3,735,330...3,744,714
Ensembl chrNW_004955455:3,735,410...3,744,107
JBrowse link
G Nefl neurofilament light chain treatment ISO RGD PMID:18772508 RGD:9698443 NCBI chrNW_004955403:47,946,413...47,951,734
Ensembl chrNW_004955403:47,946,353...47,952,026
JBrowse link
G Nefm neurofilament medium chain treatment ISO RGD PMID:18772508 RGD:9698443 NCBI chrNW_004955403:47,920,408...47,926,922 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:24747453 RGD:10412730 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment ISO RGD PMID:21134362 RGD:10413867 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520
JBrowse link
G Ngf nerve growth factor ISO RGD PMID:12499054 PMID:16915089 RGD:5144069 RGD:5144073 NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
JBrowse link
G Ngfr nerve growth factor receptor treatment ISO mRNA:increased expression:spinal cord RGD PMID:11223160 PMID:23748892 RGD:10414079 RGD:5144100 NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO RGD PMID:18687784 RGD:2311166 NCBI chrNW_004955474:5,211,281...5,214,785 JBrowse link
G Nlk nemo like kinase ISO protein:increased expression:grey matter: RGD PMID:24395089 RGD:12791278 NCBI chrNW_004955481:4,828,441...4,973,734
Ensembl chrNW_004955481:4,828,448...4,973,734
JBrowse link
G Nog noggin treatment ISO RGD PMID:18221366 RGD:10429192 NCBI chrNW_004955451:6,192,368...6,193,766
Ensembl chrNW_004955451:6,193,042...6,193,740
JBrowse link
G Nos1 nitric oxide synthase 1 ISO protein:increased expression:spinal cord RGD PMID:19291395 PMID:20633123 RGD:5131936 RGD:5132595 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
JBrowse link
G Nos2 nitric oxide synthase 2 ISO mRNA:altered expression:thoracic aorta RGD PMID:17287083 RGD:4891407 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Nos3 nitric oxide synthase 3 ISO RGD PMID:17287083 RGD:4891407 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment ISO protein:increased expression:spinal cord (rat) RGD PMID:24747453 PMID:28881715 RGD:10412730 RGD:13434916 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604
JBrowse link
G Ntf3 neurotrophin 3 ISO RGD PMID:16022868 RGD:4891112 NCBI chrNW_004955413:3,207,669...3,273,371
Ensembl chrNW_004955413:3,207,123...3,273,491
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:decreased expression:spinal cord RGD PMID:18585435 RGD:2308892 NCBI chrNW_004955545:2,929,704...2,947,579
Ensembl chrNW_004955545:2,929,704...2,947,579
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:20597685 PMID:22027236 RGD:5684547 RGD:5684898 NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO mRNA:decreased expression:spinal cord RGD PMID:18585435 RGD:2308892 NCBI chrNW_004955416:16,652,931...17,018,188
Ensembl chrNW_004955416:16,652,791...17,018,188
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 treatment ISO RGD PMID:22173726 PMID:28452182 RGD:40902836 RGD:40902844 NCBI chrNW_004955407:32,432,888...32,436,209
Ensembl chrNW_004955407:32,433,849...32,434,923
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO CTD Direct Evidence: therapeutic CTD PMID:15258577 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:15696051 PMID:21748659 RGD:10053608 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO RGD PMID:29665726 RGD:40886268 NCBI chrNW_004955542:49,290...57,747
Ensembl chrNW_004955542:49,259...58,823
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 ISO mRNA:increased expression:microglial cell RGD PMID:29665726 RGD:40886268 NCBI chrNW_004955434:9,540,047...9,559,335 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:21568693 RGD:6482306 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
G Pla2g6 phospholipase A2 group VI ISO protein:increased expression:spinal cord RGD PMID:21868473 RGD:6482718 NCBI chrNW_004955413:24,431,592...24,482,229
Ensembl chrNW_004955413:24,429,589...24,482,537
JBrowse link
G Plau plasminogen activator, urokinase ISO RGD PMID:21573723 RGD:6483797 NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:21573723 RGD:6483797 NCBI chrNW_004955555:1,378,505...1,393,395
Ensembl chrNW_004955555:1,378,793...1,393,324
JBrowse link
G Pon1 paraoxonase 1 treatment ISO RGD PMID:12897486 RGD:8547682 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Ppard peroxisome proliferator activated receptor delta ISO RGD PMID:20058304 RGD:2324875 NCBI chrNW_004955437:3,285,281...3,354,099
Ensembl chrNW_004955437:3,288,830...3,357,048
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22208735 RGD:6484263 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO protein:increased expression:spinal cord, astrocyte, microglial cell RGD PMID:29033188 RGD:13514047 NCBI chrNW_004955482:7,582,605...7,605,340
Ensembl chrNW_004955482:7,578,782...7,606,132
JBrowse link
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A ISO mRNA:increased expression:spinal cord (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17578450 PMID:29793971 RGD:9999410 NCBI chrNW_004955559:1,750,227...1,753,607
Ensembl chrNW_004955559:1,750,168...1,753,629
JBrowse link
G Prkcg protein kinase C gamma ISO protein:decreased expression:spinal cord (mouse) RGD PMID:10501452 RGD:28867228 NCBI chrNW_004955604:262,182...279,259
Ensembl chrNW_004955604:262,071...279,259
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia, macrophage RGD PMID:11063829 PMID:17184185 RGD:5688221 RGD:5688246 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18606213 RGD:5135219 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptprz1 protein tyrosine phosphatase receptor type Z1 treatment ISO RGD PMID:12895450 PMID:15016081 PMID:18065151 RGD:9589823 RGD:9590113 RGD:9590124 NCBI chrNW_004955479:3,611,658...3,734,225
Ensembl chrNW_004955479:3,624,993...3,733,183
JBrowse link
G Rara retinoic acid receptor alpha ISO RGD PMID:16420438 RGD:2314291 NCBI chrNW_004955451:14,876,663...14,917,134
Ensembl chrNW_004955451:14,897,726...14,917,134
JBrowse link
G Rbmx RNA binding motif protein X-linked ISO RGD PMID:23180094 RGD:10053723 NCBI chrNW_004955489:8,280,842...8,286,252 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO RGD PMID:17918744 RGD:2298849 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a treatment ISO RGD PMID:16585268 RGD:9850138 NCBI chrNW_004955416:21,221,023...21,261,831
Ensembl chrNW_004955416:21,221,023...21,261,831
JBrowse link
G Rpsa ribosomal protein SA ISO RGD PMID:19196078 RGD:11041651 NCBI chrNW_004955420:29,978,160...29,983,544 JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 ISO RGD PMID:16109750 PMID:16718433 RGD:2317320 RGD:2317321 NCBI chrNW_004955449:8,896,454...9,009,304
Ensembl chrNW_004955449:8,896,454...9,009,304
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:15792522 RGD:1599333 NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948
JBrowse link
G Shh sonic hedgehog signaling molecule treatment ISO RGD PMID:24837681 RGD:12879409 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 treatment ISO RGD PMID:27256506 RGD:13792677 NCBI chrNW_004955474:6,970,383...6,982,231
Ensembl chrNW_004955474:6,978,130...6,981,189
JBrowse link
G Slc25a27 solute carrier family 25 member 27 ISO protein:increased expression:spinal cord RGD PMID:18534681 RGD:6482843 NCBI chrNW_004955437:11,497,308...11,514,208
Ensembl chrNW_004955437:11,497,308...11,514,208
JBrowse link
G Slit1 slit guidance ligand 1 ISO RGD PMID:16262652 RGD:2316136 NCBI chrNW_004955507:3,204,135...3,365,319
Ensembl chrNW_004955507:3,201,556...3,365,471
JBrowse link
G Slit2 slit guidance ligand 2 ISO mRNA, protein:increased expression:spinal cord RGD PMID:19783284 RGD:2316127 NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
JBrowse link
G Slit3 slit guidance ligand 3 ISO RGD PMID:16262652 RGD:2316136 NCBI chrNW_004955408:21,719,487...22,322,958
Ensembl chrNW_004955408:21,722,632...22,322,917
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO protein:increased expression:spinal cord RGD PMID:23595775 RGD:10412063 NCBI chrNW_004955460:14,774,545...14,860,783
Ensembl chrNW_004955460:14,774,545...14,802,879
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO RGD PMID:11723173 RGD:2298928 NCBI chrNW_004955405:30,349,956...30,623,849
Ensembl chrNW_004955405:30,366,866...30,375,468
Ensembl chrNW_004955405:30,366,866...30,375,468
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human gene in a rat model
CTD Direct Evidence: therapeutic
human protein in a rat model
RGD
CTD
PMID:16689664 PMID:17457363 PMID:18722523 RGD:8655939 RGD:8655990 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sox2 SRY-box transcription factor 2 ISO mRNA, protein:increased expression:spinal cord RGD PMID:23169458 RGD:8661675 NCBI chrNW_004955420:10,671,888...10,674,080
Ensembl chrNW_004955420:10,671,978...10,672,934
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO RGD PMID:17611274 RGD:2300052 NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15592854 RGD:6483848 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016
JBrowse link
G Sqstm1 sequestosome 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:18945947 RGD:2304258 NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872
JBrowse link
G Tbp TATA-box binding protein ISO protein:increased expression:spinal cord, astrocyte, microglial cell RGD PMID:24710803 RGD:9681729 NCBI chrNW_004955411:3,268,147...3,285,567
Ensembl chrNW_004955411:3,268,147...3,285,077
JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA, protein:increased expression:spinal cord RGD PMID:15798365 PMID:23793903 RGD:11038671 RGD:2291993 NCBI chrNW_004955504:649,248...669,796
Ensembl chrNW_004955504:651,779...670,589
JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO RGD PMID:15145083 RGD:2302103 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO RGD PMID:15145083 RGD:2302103 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248
JBrowse link
G Thbd thrombomodulin ISO RGD PMID:15307903 RGD:1580060 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Thbs1 thrombospondin 1 ISO protein:increased expression:spinal cord RGD PMID:19719963 RGD:2317939 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
G Tlr1 toll like receptor 1 treatment ISO mRNA:increased expression:spinal cord (mouse) RGD PMID:21970496 RGD:7246886 NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382
JBrowse link
G Tlr4 toll like receptor 4 severity ISO RGD PMID:25990044 RGD:14700556 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tnc tenascin C ISO mRNA:increased expression:spinal cord RGD PMID:11085900 RGD:4889619 NCBI chrNW_004955419:12,569,620...12,662,897
Ensembl chrNW_004955419:12,569,547...12,662,958
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:20633123 RGD:5131936 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:cerebrospinal fluid RGD PMID:16083358 RGD:1624185 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Tp53 tumor protein p53 ISO protein:increased expression:spinal cord RGD PMID:23595775 RGD:10412063 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 ISO mRNA,protein:increased expression:urinary bladder, dorsal root ganglion: RGD PMID:21367919 RGD:10043365 NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372
JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 treatment ISO RGD PMID:19169264 PMID:25763638 RGD:10003030 RGD:12791993 NCBI chrNW_004955559:1,539,036...1,581,800
Ensembl chrNW_004955559:1,546,365...1,581,712
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 ISO protein:increased expression:neuron, axon RGD PMID:25040536 RGD:11553820 NCBI chrNW_004955482:760,200...777,133
Ensembl chrNW_004955482:761,811...777,133
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:spinal cord
CTD
RGD
PMID:21092735 RGD:5148013 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO RGD PMID:20125055 RGD:2325181 NCBI chrNW_004955561:1,573,525...1,578,295
Ensembl chrNW_004955561:1,573,525...1,580,511
JBrowse link
G Vim vimentin ISO protein:increased expression:spinal cord RGD PMID:10225952 PMID:21250919 RGD:6480471 RGD:6480511 NCBI chrNW_004955429:10,708,852...10,716,743
Ensembl chrNW_004955429:10,707,719...10,717,554
JBrowse link
G Vwf von Willebrand factor ISO RGD PMID:25771801 RGD:13673888 NCBI chrNW_004955413:3,672,470...3,825,588
Ensembl chrNW_004955413:3,672,470...3,819,571
JBrowse link
G Xbp1 X-box binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29793971 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
G Xylt1 xylosyltransferase 1 ISO RGD PMID:18765417 RGD:2313145 NCBI chrNW_004955442:1,787,338...2,042,523
Ensembl chrNW_004955442:1,745,924...2,036,340
JBrowse link
Spinal Cord Compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13 ISO mRNA, protein:increased expression, increased activity:spinal cord (rat) RGD PMID:22425718 RGD:10449098 NCBI chrNW_004955513:2,761,386...2,786,447
Ensembl chrNW_004955513:2,764,186...2,786,187
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 ISO mRNA, protein:increased expression:dorsal root ganglion (rat) RGD PMID:23613963 RGD:14390159 NCBI chrNW_004955532:1,618,659...1,621,706
Ensembl chrNW_004955532:1,619,532...1,621,064
JBrowse link
G Egr1 early growth response 1 ISO protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:20675054 RGD:5131876 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007
JBrowse link
G Epo erythropoietin ISO protein:increased expression:neuron, endothelium, glia: RGD PMID:15792521 RGD:11041719 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G Epor erythropoietin receptor ISO protein:increased expression:neuron, endothelium, glia: RGD PMID:15792521 RGD:11041719 NCBI chrNW_004955495:2,293,587...2,299,302
Ensembl chrNW_004955495:2,293,540...2,298,715
JBrowse link
G Fas Fas cell surface death receptor treatment ISO human protein in a rat model
protein:increased expression:spinal cord:
RGD PMID:16202410 PMID:16689665 PMID:21490053 RGD:12904017 RGD:1582444 RGD:8663485 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Faslg Fas ligand treatment ISO protein:increased expression:spinal cord: RGD PMID:21490053 RGD:12904017 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO protein:increased expression:spinal cord RGD PMID:17244329 RGD:8655633 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
JBrowse link
G Fis1 fission, mitochondrial 1 treatment ISO RGD PMID:25595990 RGD:12437079 NCBI chrNW_004955456:16,057,158...16,060,623
Ensembl chrNW_004955456:16,038,221...16,060,623
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO protein:decreased expression:spinal cord, thoracic vertebrae (rat) RGD PMID:20399821 RGD:2326108 NCBI chrNW_004955446:18,978,261...18,996,794
Ensembl chrNW_004955446:18,978,102...18,998,951
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:spinal cord (mouse) RGD PMID:21787762 RGD:6218959 NCBI chrNW_004955408:4,379,825...4,422,710
Ensembl chrNW_004955408:4,379,825...4,423,381
JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:cerebrospinal fluid, serum RGD PMID:30327453 RGD:14975119 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G L1cam L1 cell adhesion molecule ISO RGD PMID:21671795 RGD:6483029 NCBI chrNW_004955580:548,442...561,580
Ensembl chrNW_004955580:549,368...561,486
JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO RGD PMID:29323048 RGD:13504709 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12227717 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15135227 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:spinal cord (rat) RGD PMID:21224756 RGD:5130917 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:spinal cord (rat)
human protein in rat model
RGD PMID:21224756 RGD:5130917 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12762
    Wounds and Injuries 784
      Spinal Cord Injuries 249
        Autonomic Dysreflexia 0
        Central Cord Syndrome 0
        Spinal Cord Compression 18
Path 2
Term Annotations click to browse term
  disease 12762
    disease of anatomical entity 12446
      nervous system disease 10344
        central nervous system disease 9060
          spinal cord disease 1478
            Spinal Cord Injuries 249
              Autonomic Dysreflexia 0
              Central Cord Syndrome 0
              Spinal Cord Compression 18
paths to the root