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Term:Graves Ophthalmopathy
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Accession:DOID:9000008 term browser browse the term
Definition:An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.
Synonyms:exact_synonym: Congestive Ophthalmopathies;   Congestive Ophthalmopathy;   Dysthyroid Ophthalmopathies;   Dysthyroid Ophthalmopathy;   Edematous Ophthalmopathies;   Edematous Ophthalmopathy;   Infiltrative Ophthalmopathies;   Infiltrative Ophthalmopathy;   Myopathic Ophthalmopathies;   Myopathic Ophthalmopathy;   Thyroid Associated Ophthalmopathies;   Thyroid Associated Ophthalmopathy;   Thyroid Eye Disease
 narrow_synonym: Graves' Orbitopathy;   Thyroid-Associated Orbitopathy
 primary_id: MESH:D049970;   RDO:0007562
For additional species annotation, visit the Alliance of Genome Resources.

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Graves Ophthalmopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link NW_004936533 3,601,270 3,637,128 RGD:9068941
G Ctla4 cytotoxic T-lymphocyte associated protein 4 JBrowse link NW_004936631 484,356 489,643 RGD:9068941
G Icam1 intercellular adhesion molecule 1 JBrowse link NW_004936659 616,570 627,172 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004936545 6,139,130 6,144,543 RGD:9068941
G Igf1 insulin like growth factor 1 JBrowse link NW_004936492 11,709,623 11,784,028 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004936557 5,834,874 5,838,502 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004936612 2,306,963 2,325,086 RGD:9068941
G Il1a interleukin 1 alpha JBrowse link NW_004936783 1,210,715 1,218,315 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004936783 1,447,158 1,466,331 RGD:9068941
G Il2 interleukin 2 JBrowse link NW_004936662 1,594,953 1,599,625 RGD:9068941
G Il23r interleukin 23 receptor JBrowse link NW_004936591 4,365,598 4,425,053 RGD:9068941
G Il3 interleukin 3 JBrowse link NW_004936647 3,102,922 3,104,758 RGD:9068941
G Kif1a kinesin family member 1A JBrowse link NW_004936745 911,651 976,878 RGD:9068941
G Pparg peroxisome proliferator activated receptor gamma JBrowse link NW_004936602 1,230,907 1,368,588 RGD:9068941
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link NW_004936481 3,821,564 3,828,086 RGD:9068941
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 JBrowse link NW_004936690 2,180,804 2,232,869 RGD:9068941
G Serpine1 serpin family E member 1 JBrowse link NW_004936543 1,032,543 1,040,956 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
G Tshr thyroid stimulating hormone receptor JBrowse link NW_004936488 9,428,053 9,560,856 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11879
    sensory system disease 4380
      eye disease 2149
        Hereditary Eye Diseases 500
          Graves Ophthalmopathy 19
Path 2
Term Annotations click to browse term
  disease 11879
    disease of anatomical entity 11444
      musculoskeletal system disease 4771
        connective tissue disease 3347
          bone disease 2891
            orbital disease 56
              exophthalmos 54
                Graves' disease 53
                  Graves Ophthalmopathy 19
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.