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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:salivary gland cancer
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Accession:DOID:8850 term browser browse the term
Definition:An oral cavity cancer that is located_in the salivary gland. (DO)
Synonyms:exact_synonym: cancer of salivary gland;   malignant neoplasm of salivary gland;   malignant tumor of the salivary gland
 xref: ICD10CM:C08;   ICD9CM:142.8
For additional species annotation, visit the Alliance of Genome Resources.



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salivary gland cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gon4l gon-4 like ISS MouseDO NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
JBrowse link
mucoepidermoid carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Cdh1 cadherin 1 ISO DNA:hypermethylation:promoter: RGD PMID:15999364 RGD:9588574 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:saliva-secreting gland (human) RGD PMID:28772134 RGD:152023620 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO RGD PMID:15999364 RGD:9588574 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO DNA:SNP:intron: (rs3748522) (human) RGD PMID:26035306 RGD:151361290 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
salivary gland adenoid cystic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir155 microRNA 155 disease_progression ISO RGD PMID:28668836 RGD:24922215 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 disease_progression ISO RGD PMID:25885343 RGD:25330345 NCBI chr16:51,202,497...51,347,791
Ensembl chr16:51,253,562...51,347,793
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 susceptibility ISO DNA:SNP:intron: (rs13180356) (human) RGD PMID:26035306 RGD:151361290 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
salivary gland carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdr kinase insert domain receptor disease_progression ISO RGD PMID:26498950 RGD:126907998 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 disease_progression ISO RGD PMID:26498950 RGD:126907998 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein sexual_dimorphism ISO DNA:SNP:intron: (rs3748522) (human) RGD PMID:26035306 RGD:151361290 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 sexual_dimorphism ISO DNA:SNP:intron: (rs13180356) (human) RGD PMID:26035306 RGD:151361290 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18032
    sensory system disease 6469
      mouth disease 829
        Mouth Neoplasms 243
          Salivary Gland Neoplasms 61
            salivary gland cancer 11
              epithelial-myoepithelial carcinoma 0
              parotid gland cancer + 0
              pleomorphic adenoma carcinoma 0
              salivary gland carcinoma + 10
              sublingual gland cancer + 0
              submandibular gland cancer 0
Path 2
Term Annotations click to browse term
  disease 18032
    disease of cellular proliferation 7258
      Neoplasms by Site 6884
        Digestive System Neoplasms 3603
          Gastrointestinal Neoplasms 3475
            gastrointestinal system cancer 2707
              oral cavity cancer 114
                salivary gland cancer 11
                  epithelial-myoepithelial carcinoma 0
                  parotid gland cancer + 0
                  pleomorphic adenoma carcinoma 0
                  salivary gland carcinoma + 10
                  sublingual gland cancer + 0
                  submandibular gland cancer 0
paths to the root