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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:decubitus ulcer
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Accession:DOID:8717 term browser browse the term
Definition:An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.
Synonyms:exact_synonym: Bed Sore;   Bed Sores;   Bedsore;   Bedsores;   Decubitus Ulcers;   Pressure Sore;   Pressure Sores;   Pressure Ulcer;   Pressure Ulcers;   decubitus (pressure) ulcer;   decubitus ulcer any site
 primary_id: MESH:D003668
 xref: ICD10CM:L89;   ICD10CM:L89.9;   ICD9CM:707.0;   NCI:C50706
For additional species annotation, visit the Alliance of Genome Resources.


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decubitus ulcer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 IEP RGD PMID:23740668 RGD:8655548 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP mRNA, protein:increased expression:deep dorsal muscles (rat) RGD PMID:20223667 RGD:8694460 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Il10 interleukin 10 IEP mRNA:increased expression:skin RGD PMID:26177082 RGD:11049489 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:skin: RGD PMID:12692851 RGD:8551845 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Vegfa vascular endothelial growth factor A ISO
IEP
protein:increased expression:skin: RGD PMID:12692851, PMID:23740668 RGD:8551845, RGD:8655548 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16123
    sensory system disease 5245
      skin disease 2715
        chronic ulcer of skin 38
          decubitus ulcer 5
Path 2
Term Annotations click to browse term
  disease 16123
    disease of anatomical entity 15370
      nervous system disease 10975
        sensory system disease 5245
          skin disease 2715
            chronic ulcer of skin 38
              decubitus ulcer 5
paths to the root