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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:substance-induced psychosis
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Accession:DOID:8646 term browser browse the term
Definition:Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.
Synonyms:exact_synonym: Drug Psychoses;   Toxic Psychoses;   substance-induced psychoses
 primary_id: MESH:D011605;   RDO:0006434
 xref: ICD9CM:293.89
For additional species annotation, visit the Alliance of Genome Resources.


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substance-induced psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20799992 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21041608 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Camk2b calcium/calmodulin dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17603807 NCBI chrNW_004936478:19,183,493...19,278,457 JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19386276 NCBI chrNW_004936489:4,616,839...4,887,179 JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20211215 NCBI chrNW_004936529:3,042,220...3,053,670 JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15729709 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19747927 NCBI chrNW_004936480:5,042,531...5,047,157 JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705401 NCBI chrNW_004936474:5,848,719...5,858,520 JBrowse link
G LOC101958197 regulator of G protein signaling 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17318883 NCBI chrNW_004936541:7,472,195...7,525,220 JBrowse link
G LOC101968921 angiotensin-converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:17196621 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19566775 NCBI chrNW_004936555:2,267,727...2,276,673 JBrowse link
G Oprm1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402083 NCBI chrNW_004936489:6,506,207...6,567,136 JBrowse link
G Phb prohibitin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18504422 NCBI chrNW_004936490:12,127,065...12,138,870 JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17606663 NCBI chrNW_004936492:3,098,196...3,115,921 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12931138 NCBI chrNW_004936815:359,775...400,690 JBrowse link
G Snca synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15542733 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16807759 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
alcohol-induced mental disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26711020 NCBI chrNW_004936558:4,362,693...4,387,705 JBrowse link
G Foxo4 forkhead box O4 ISO protein:increased phosphorylation:small intestine: RGD PMID:23292333 RGD:10402360 NCBI chrNW_004936762:495,271...501,278 JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO RGD PMID:24972622 RGD:10401897 NCBI chrNW_004936792:531,076...579,083 JBrowse link
drug psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 ISO RGD PMID:26174132 RGD:11534754 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
fetal alcohol spectrum disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chrNW_004936614:2,664,594...2,976,174 JBrowse link
G Apoe apolipoprotein E ISO RGD PMID:15007105 RGD:12904641 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:26074427 NCBI chrNW_004936533:3,601,270...3,637,128 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B treatment ISO RGD PMID:22037411 PMID:23763370 RGD:13210751 RGD:13432044 NCBI chrNW_004936587:3,406,055...3,806,956 JBrowse link
G Igf1 insulin like growth factor 1 ISO mRNA:decreased expression:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO protein:decreased activity:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chrNW_004936483:4,563,995...4,860,231 JBrowse link
G Nos1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25511929 NCBI chrNW_004936558:5,162,471...5,302,488 JBrowse link
G Pten phosphatase and tensin homolog ISO Protein:increased expression, increased activity:cerebellum (rat) RGD PMID:12700235 RGD:12801493 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chrNW_004936474:10,996,867...11,030,504 JBrowse link
fetal alcohol syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A ISO protein:increased activation:neuron, cerebellum RGD PMID:17109064 RGD:2298867 NCBI chrNW_004936529:1,000,050...1,045,655 JBrowse link
Postoperative Cognitive Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:24814703 RGD:10047100 NCBI chrNW_004936519:6,831,096...6,873,977 JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:22959208 RGD:7204702 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:23077050 RGD:8551854 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO protein:increased expression:hippocampus (rat) RGD PMID:23229539 RGD:12904023 NCBI chrNW_004936471:36,547,552...36,601,327 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11995
    Chemically-Induced Disorders 928
      substance-related disorder 462
        substance-induced psychosis 35
          alcohol-induced mental disorder + 13
          alcoholic psychosis 0
          drug-induced mental disorder + 1
          subacute delirium + 4
Path 2
Term Annotations click to browse term
  disease 11995
    disease of anatomical entity 11563
      nervous system disease 9501
        central nervous system disease 8051
          brain disease 7460
            disease of mental health 5430
              cognitive disorder 1623
                psychotic disorder 942
                  substance-induced psychosis 35
                    alcohol-induced mental disorder + 13
                    alcoholic psychosis 0
                    drug-induced mental disorder + 1
                    subacute delirium + 4
paths to the root