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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:subacute delirium
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Accession:DOID:8645 term browser browse the term
Definition:A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)
Synonyms:exact_synonym: Delirium of Mixed Origin;   Mixed Origin Delirium;   delirium;   mixed origin deliriums;   subacute deliriums
 primary_id: MESH:D003693
 xref: EFO:0009267;   ICD9CM:293.1
For additional species annotation, visit the Alliance of Genome Resources.


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Postoperative Cognitive Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:24814703 RGD:10047100 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G BDNF brain derived neurotrophic factor treatment ISO associated with brain ischemia RGD PMID:29571823 PMID:29599834 PMID:34964700 RGD:401959211 RGD:401965400 RGD:401976548 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:29571823 PMID:36688960 PMID:37736695 RGD:401959211 RGD:401959611 RGD:401960090 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130 		JBrowse link
G GDNF glial cell derived neurotrophic factor ISO protein:decreased expression:hippocampus,urine RGD PMID:36688960 RGD:401959611 NCBI chr 5:72,539,374...72,566,918
Ensembl chr 5:77,577,313...77,601,362 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO protein:increased expression:plasma (human) RGD PMID:25543030 RGD:401960875 NCBI chr 4:66,808,845...66,888,301
Ensembl chr 4:73,382,745...73,462,087 		JBrowse link
G IL1B interleukin 1 beta treatment ISO protein:increased expression:hippocampus (rat) RGD PMID:22959208 PMID:29571823 PMID:33390808 RGD:401959211 RGD:401965467 RGD:7204702 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:23077050 RGD:8551854 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:hippocampus (rat) RGD PMID:33390808 RGD:401965467 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IREB2 iron responsive element binding protein 2 ISO protein:increased expression:hippocampus (rat) RGD PMID:23229539 RGD:12904023 NCBI chr15:57,367,314...57,430,322
Ensembl chr15:76,331,610...76,394,476 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611 RGD:401960090 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611 RGD:401960090 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G NGF nerve growth factor treatment ISO associated with brain ischemia RGD PMID:29599834 PMID:30481505 PMID:34964700 RGD:401965395 RGD:401965400 RGD:401976548 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 ISO protein:increased expression:hippocampus (rat) RGD PMID:33390808 RGD:401965467 NCBI chr 4:140,418,624...140,785,180
Ensembl chr 4:152,108,508...152,430,298 		JBrowse link
G TNF tumor necrosis factor treatment ISO protein:increased expression:hippocampus (rat) RGD PMID:29571823 PMID:33390808 RGD:401959211 RGD:401965467 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17996
    Chemically-Induced Disorders 1174
      Poisoning 638
        substance-induced psychosis 71
          subacute delirium 14
            Postoperative Cognitive Dysfunction 14
Path 2
Term Annotations click to browse term
  disease 17996
    disease of anatomical entity 15260
      nervous system disease 13293
        central nervous system disease 11923
          brain disease 11204
            disease of mental health 8111
              Schizophrenia Spectrum and Other Psychotic Disorders 1176
                psychotic disorder 1170
                  substance-induced psychosis 71
                    subacute delirium 14
                      Postoperative Cognitive Dysfunction 14
paths to the root