Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:ulcerative colitis
go back to main search page
Accession:DOID:8577 term browser browse the term
Definition:A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores. (DO)
Synonyms:exact_synonym: Colitis Gravis;   Idiopathic Proctocolitis;   Inflammatory Bowel Disease, Ulcerative Colitis Type;   left-sided ulcerative colitis
 primary_id: MESH:D003093
 xref: ICD10CM:K51;   ICD9CM:556;   ICD9CM:556.5;   NCI:C2952
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb2 adrenoceptor beta 2 IEP protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alpi alkaline phosphatase, intestinal ISO protein:decreased expression:colonic mucosa RGD PMID:22783049 RGD:14367879 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Apoa4 apolipoprotein A4 severity ISO DNA:missense mutation:cds:p.Q360H (human) RGD PMID:17206692 RGD:5685660 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chr20:4,140,184...4,156,365
Ensembl chr20:4,141,878...4,154,978
JBrowse link
G Card9 caspase recruitment domain family, member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 3:3,798,346...3,806,841
Ensembl chr 3:3,798,347...3,806,713
JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16306769, PMID:21887805 RGD:7488892 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO protein:increased expression:colon RGD PMID:10433925 RGD:6483784 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr17:62,332,537...62,462,644
Ensembl chr17:62,332,537...62,462,644
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:21077277 RGD:6892920 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain IEP Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:17939044 RGD:5688304 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells (human) RGD PMID:21087446 RGD:6480657 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells (human) RGD PMID:21087446 RGD:6480657 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Dap death-associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Defa5 defensin alpha 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr16:75,338,050...75,340,401
Ensembl chr16:75,338,052...75,340,360
JBrowse link
G Ecm1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F2 coagulation factor II ISO RGD PMID:21593018 RGD:5147754 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:30122878 RGD:13792562 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:30122878 RGD:13792562 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa susceptibility ISO DNA:polymorphism: :p.A519G (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1801274 (human)
CTD PMID:19915573, PMID:20228799, PMID:20848524, PMID:19915573 RGD:5147918, RGD:5147922 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Gc GC, vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Gna12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212
JBrowse link
G Gpr65 G-protein coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chr 6:122,248,528...122,256,115
Ensembl chr 6:122,254,841...122,256,251
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649, PMID:28626742, PMID:26604430 RGD:5490554, RGD:14700999, RGD:11538341 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649, PMID:26604430 RGD:5490554, RGD:11538341 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr 1:114,453,033...114,653,787
Ensembl chr 1:114,453,054...114,653,793
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnmt histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO
mRNA:increased expression:substantia nigra (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:15553846, PMID:20584104 RGD:4145388 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Icoslg inducible T-cell co-stimulator ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr20:11,330,000...11,340,307
Ensembl chr20:11,329,992...11,340,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448, PMID:20228799, PMID:26660358, PMID:28120341 RGD:14975255, RGD:14975153 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799, PMID:21297633 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD PMID:12133438, PMID:15955209, PMID:20452301, PMID:22119283, PMID:24812904 RGD:10450593 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il23r interleukin 23 receptor ISO DNA:SNP,Haplotype: :rs1884444(human)
CTD Direct Evidence: marker/mechanism
CTD PMID:18438406, PMID:19122664, PMID:20228799, PMID:23093364 RGD:8549574 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173
JBrowse link
G Il33 interleukin 33 treatment ISO mRNA:increased expression:sigmoid colon RGD PMID:25112700, PMID:28802904 RGD:39938951, RGD:39938966 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il7r interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633
G Irf5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 4:56,804,477...56,816,271
Ensembl chr 4:56,805,132...56,820,543
JBrowse link
G Irgm immunity-related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:20228799, PMID:21297633, PMID:22269120 RGD:6483020 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kif21b kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr13:52,976,505...53,026,750
Ensembl chr13:52,976,507...53,023,103
JBrowse link
G Lamb1 laminin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lsp1 lymphocyte-specific protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:215,628,750...215,662,505
Ensembl chr 1:215,628,785...215,662,504
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Masp2 mannan-binding lectin serine peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 5:165,415,105...165,429,857
Ensembl chr 5:165,415,136...165,430,054
JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:colon
miRNA:decreased expression:feces
RGD PMID:30927737, PMID:29438285, PMID:29325325, PMID:29668922 RGD:21079443, RGD:21403682, RGD:24922207, RGD:24922213 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir31 microRNA 31 ISO miRNA:increased expression:colon RGD PMID:29438285 RGD:21403682 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mmp1 matrix metallopeptidase 1 IDA RGD PMID:18837084 RGD:7207395 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826, PMID:22119283, PMID:24055189 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming IEP mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405, PMID:18438406, PMID:20228799 NCBI chr 1:263,361,238...263,371,043
Ensembl chr 1:263,367,266...263,370,219
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:colon (human) RGD PMID:17664137 RGD:5509924 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:colon (human) RGD PMID:17664137 RGD:5509924 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Psmg1 proteasome assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr11:36,327,798...36,337,289
Ensembl chr11:36,327,800...36,337,256
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:21818367 RGD:6483532 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:17429720 RGD:2300267 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:17429720 RGD:2300267 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Rnf170 ring finger protein 170 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chr16:70,684,886...70,710,147
Ensembl chr16:70,687,487...70,705,128
JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO RGD PMID:31038770 RGD:14865009 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25559196 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Sell selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO DNA:transition, repeat:promoter:-237C>T (human)
DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:16059695, PMID:18340647, PMID:11929588 RGD:5684939, RGD:5684968 NCBI chr 9:81,655,590...81,666,697
Ensembl chr 9:81,655,629...81,666,706
JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chr 6:50,725,085...50,766,306
Ensembl chr 6:50,725,085...50,766,300
JBrowse link
G Sphk1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:18438405, PMID:20228799, PMID:22269120 RGD:6483020 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chr 1:41,608,287...41,763,591
NCBI chr 1:41,844,840...42,086,662
Ensembl chr 1:41,608,418...42,077,535
JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD PMID:19617644, PMID:20452301, PMID:22119283, PMID:25204186, PMID:28120341, PMID:24812904 RGD:10450577, RGD:14975153, RGD:10450593 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:plasma, large intestine mucosa RGD PMID:19013462 RGD:5684406 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vip vasoactive intestinal peptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr 8:130,283,453...130,313,431 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16058
    disease of anatomical entity 15305
      gastrointestinal system disease 4621
        autoimmune disease of gastrointestinal tract 249
          ulcerative colitis 110
            Pediatric Ulcerative Colitis 0
Path 2
Term Annotations click to browse term
  disease 16058
    disease of anatomical entity 15305
      Immune & Inflammatory Diseases 3506
        immune system disease 2926
          primary immunodeficiency disease 2346
            autoimmune disease 1666
              autoimmune disease of gastrointestinal tract 249
                ulcerative colitis 110
                  Pediatric Ulcerative Colitis 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.