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Term:chronic fatigue syndrome
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Accession:DOID:8544 term browser browse the term
Definition:A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
Synonyms:exact_synonym: CFS;   Chronic Fatigue Disorder;   Chronic Fatigue Disorders;   Chronic Fatigue Fibromyalgia Syndrome;   Chronic Fatigue Syndromes;   Chronic Fatigue-Fibromyalgia Syndromes;   Infectious Mononucleosis Like Syndrome, Chronic;   Myalgic Encephalomyelitis;   Postviral Fatigue Syndrome;   Royal Free Disease;   chronic fatigue and immune dysfunction syndrome;   myalgic encephalitis;   postviral fatigue syndromes
 primary_id: MESH:D015673
 alt_id: RDO:0006912
 xref: GARD:7121;   ICD10CM:G93.3;   ICD10CM:R53.82;   ICD9CM:780.71;   NCI:C3037
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chronic fatigue syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl24 C-C motif chemokine ligand 24 JBrowse link 12 24,131,529 24,152,626 RGD:11538286
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:5131614
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:11538286
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:11538286
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:5509831
G Il16 interleukin 16 JBrowse link 1 145,781,923 145,881,538 RGD:11538286
G Prf1 perforin 1 JBrowse link 20 30,915,294 30,920,804 RGD:6482801
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6892702
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:5147827
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11538286

Term paths to the root
Path 1
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  disease 15603
    syndrome 5215
      chronic fatigue syndrome 10
Path 2
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  disease 15603
    disease of anatomical entity 14934
      nervous system disease 10239
        peripheral nervous system disease 2138
          neuropathy 1960
            neuromuscular disease 1530
              muscular disease 968
                chronic fatigue syndrome 10
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