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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:herpes zoster
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Accession:DOID:8536 term browser browse the term
Definition:An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)
Synonyms:exact_synonym: herpes zona;   shingles;   zona;   zoster
 primary_id: MESH:D006562
 xref: ICD10CM:B02;   ICD9CM:053;   NCI:C71079
For additional species annotation, visit the Alliance of Genome Resources.


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herpes zoster term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO protein:decreased expression:: RGD PMID:21954956 RGD:8663478 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il2 interleukin 2 ISO protein:increased expression:: RGD PMID:21954956 RGD:8663478 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Il4 interleukin 4 ISO protein:decreased expression:: RGD PMID:21954956 RGD:8663478 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:: RGD PMID:21954956 RGD:8663478 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11834
    disease of anatomical entity 11389
      nervous system disease 9331
        herpes zoster 4
          Herpes Zoster Ophthalmicus 0
          Zoster Sine Herpete 0
          herpes zoster oticus 0
Path 2
Term Annotations click to browse term
  disease 11834
    disease by infectious agent 1549
      viral infectious disease 1291
        DNA Virus Infections 157
          Herpesviridae Infections 89
            herpes zoster 4
              Herpes Zoster Ophthalmicus 0
              Zoster Sine Herpete 0
              herpes zoster oticus 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.