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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:lung disease
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Accession:DOID:850 term browser browse the term
Definition:A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide. (DO)
Synonyms:exact_synonym: LUNG DISEASE, NON-SPECIFIC;   Pulmonary Disease;   Pulmonary Diseases;   lung diseases
 narrow_synonym: CHRONIC LUNG DISEASE
 primary_id: MESH:D008171
 xref: EFO:0003818;   EFO:0009910;   ICD10CM:J98.4;   NCI:C3198
For additional species annotation, visit the Alliance of Genome Resources.

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      disease 21086
        disease of anatomical entity 18146
          respiratory system disease 3584
            lower respiratory tract disease 2271
              lung disease 2236
                46,XX Sex Reversal with Dysgenesis of Kidneys, Adrenals, and Lungs 2
                Alpha-2-Macroglobulin Deficiency 0
                Bacterial Lung Diseases + 148
                CHOPS Syndrome 1
                Congenital Pulmonary Lymphangiectasia 1
                Cystic Adenomatoid Malformation of Lung, Congenital 0
                Cystic Disease of Lung 0
                Fungal Lung Diseases + 55
                Hemoptysis 0
                Kashani Strom Utley Syndrome 0
                Lung Agenesis + 10
                Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome 2
                Lung Injury + 287
                Lung Neoplasms + 1005
                Parasitic Lung Diseases + 2
                Pulmonary Atelectasis + 1
                Pulmonary Function 0
                Pulmonary Hemorrhage + 2
                acute chest syndrome 6
                adult respiratory distress syndrome 107
                alpha 1-antitrypsin deficiency 1
                alveolar echinococcosis 4
                capillariasis 0
                cystic echinococcosis 5
                cystic fibrosis + 108
                dirofilariasis 0
                hepatopulmonary syndrome 8
                hyperlucent lung 0
                interstitial lung disease + 494
                lung abscess 0
                lymphangioleiomyomatosis 21
                maple bark strippers' lung 0
                middle lobe syndrome 1
                newborn respiratory distress syndrome + 205
                obstructive lung disease + 471
                paracoccidioidomycosis + 13
                phaeohyphomycosis + 0
                pneumonia + 286
                pneumonic plague 0
                pulmonary alveolar microlithiasis 1
                pulmonary alveolar proteinosis + 16
                pulmonary artery disease + 35
                pulmonary eosinophilia + 21
                pulmonary hemosiderosis 2
                pulmonary hypertension + 395
                pulmonary immaturity 0
                pulmonary plasma cell granuloma 2
                pulmonary systemic sclerosis 0
                pulmonary tuberculosis + 87
                respiratory failure + 386
                scimitar syndrome + 6
                sparganosis 0
                syndromic microphthalmia 9 3
                toxocariasis + 3
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