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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:corneal ulcer
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Accession:DOID:8463 term browser browse the term
Definition:Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
Synonyms:exact_synonym: Ulcerative Keratitides;   Ulcerative Keratitis
 primary_id: MESH:D003320
 xref: ICD10CM:H16.0;   ICD9CM:370.0;   NCI:C50515
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
corneal ulcer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO associated with Arthritis,Rheumatoid;mRNA:increased expression:keratocyte: RGD PMID:12714388 RGD:7829721 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO associated with Hypersensitivity;mRNA:decreased expression:eye RGD PMID:16251127 RGD:7364739 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:24244623 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Serpinf1 serpin family F member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19553628 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Tnf tumor necrosis factor ISO associated with Arthritis,Rheumatoid;mRNA:increased expression:keratocyte: RGD PMID:12714388 RGD:7829721 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18215
    Pathological Conditions, Signs and Symptoms 11356
      Pathologic Processes 7814
        Ulcer 133
          corneal ulcer 5
            Keratoactinomycosis 0
            Mooren's ulcer 0
            central corneal ulcer 0
            marginal corneal ulcer 0
            mycotic corneal ulcer 0
            perforated corneal ulcer 0
            ring corneal ulcer 0
Path 2
Term Annotations click to browse term
  disease 18215
    disease of anatomical entity 17576
      nervous system disease 13208
        sensory system disease 6435
          eye disease 2964
            corneal disease 209
              keratitis 67
                corneal ulcer 5
                  Keratoactinomycosis 0
                  Mooren's ulcer 0
                  central corneal ulcer 0
                  marginal corneal ulcer 0
                  mycotic corneal ulcer 0
                  perforated corneal ulcer 0
                  ring corneal ulcer 0
paths to the root