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ONTOLOGY REPORT - ANNOTATIONS


Term:periodontitis
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Accession:DOID:824 term browser browse the term
Definition:Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
Synonyms:exact_synonym: Pericementitides;   Pericementitis;   Periodontitides;   chronic pericementitis
 primary_id: MESH:D010518
 alt_id: RDO:0006318
 xref: ICD10CM:K05.3;   NCI:C34918
For additional species annotation, visit the Alliance of Genome Resources.


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periodontitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129135
RGD:7241545
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6784499
RGD:7245487
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:13801025
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:2306992
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:5688142
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:7191232
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:11352302
G Cldn1 claudin 1 JBrowse link 11 77,815,216 77,830,373 RGD:11344891
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:11554173
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:2306575
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:5135002
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:14700983
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450515
G Fmod fibromodulin JBrowse link 13 50,874,886 50,885,503 RGD:2315079
G Fpr1 formyl peptide receptor 1 JBrowse link 1 59,759,025 59,767,258 RGD:8554872
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:11554173
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:9685136
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700983
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402172
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:6480271
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364998
RGD:14975259
RGD:14975132
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6906881
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6906881
RGD:10450515
RGD:14975132
RGD:10450598
RGD:7175547
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6906881
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1601588
RGD:14975132
G Jak1 Janus kinase 1 JBrowse link 5 119,982,503 120,091,452 RGD:18936995
RGD:18936997
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:9685198
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:2317520
G Mme membrane metallo-endopeptidase JBrowse link 2 153,799,203 153,880,910 RGD:13801025
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207044
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:10043174
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2325939
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:2325862
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:11554173
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:13781894
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:5684768
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:10413909
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6771178
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:10041024
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:5509938
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:18936995
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:18936995
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10450598
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:7240508
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1331525
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:5685624
aggressive periodontitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brinp3 BMP/retinoic acid inducible neural specific 3 JBrowse link 13 63,526,486 63,959,390 RGD:14398489
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8661707
G Ccr2 C-C motif chemokine receptor 2 RGD:8661707
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:5688299
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491835
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:7240710
RGD:8554872
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700939
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:14700939
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:14975139
RGD:14975264
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:8662884
RGD:8662885
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:5147873
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:14975139
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:13592920
Chronic Periodontitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brinp3 BMP/retinoic acid inducible neural specific 3 JBrowse link 13 63,526,486 63,959,390 RGD:14398485
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8661721
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6483776
G Ccr2 C-C motif chemokine receptor 2 RGD:8661721
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:6480655
RGD:11554173
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:6480655
G Dsc1 desmocollin 1 JBrowse link 18 11,877,918 11,906,828 RGD:6480655
G Dsg1 desmoglein 1 JBrowse link 18 12,008,301 12,040,337 RGD:6480655
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:10045837
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700939
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:14975127
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:6480655
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7206856
RGD:7207046
RGD:7207045
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480655
RGD:13207324
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:13207324
G Nes nestin JBrowse link 2 187,343,109 187,352,972 RGD:6480655
G Rac2 Rac family small GTPase 2 JBrowse link 7 119,769,708 119,797,111 RGD:6480655
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:7794852
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:7794852
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7794852
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:7794852
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:14402032
EHLERS-DANLOS SYNDROME, PERIODONTAL TYPE, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1r complement C1r JBrowse link 4 157,126,060 157,136,825 RGD:8554872
G C1s complement C1s JBrowse link 4 157,143,592 157,155,592 RGD:8554872
RGD:7240710
periapical granuloma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6483772
G Ccr2 C-C motif chemokine receptor 2 RGD:8661719
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:6893426
periapical periodontitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8661717
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6483772
G Ccr2 C-C motif chemokine receptor 2 RGD:8661717
G Ciita class II, major histocompatibility complex, transactivator JBrowse link 10 5,212,621 5,260,641 RGD:7242892
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:7257692
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:11554173
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:4832829
suppurative periapical periodontitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450566

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15502
    Stomatognathic Diseases 878
      tooth disease 246
        periodontal disease 104
          periodontitis 73
            Aggressive Periodontitis, 2 0
            Chronic Periodontitis 23
            EHLERS-DANLOS SYNDROME, PERIODONTAL TYPE, 2 2
            Hypotrichosis-Osteolysis-Periodontitis-Palmoplantar Keratoderma Syndrome 0
            Periodontal Abscess 0
            Periodontal Pocket 0
            acute pericementitis 0
            aggressive periodontitis 13
            periapical periodontitis + 9
Path 2
Term Annotations click to browse term
  disease 15502
    disease of anatomical entity 14856
      nervous system disease 10270
        sensory system disease 4663
          mouth disease 686
            tooth disease 246
              periodontal disease 104
                periodontitis 73
                  Aggressive Periodontitis, 2 0
                  Chronic Periodontitis 23
                  EHLERS-DANLOS SYNDROME, PERIODONTAL TYPE, 2 2
                  Hypotrichosis-Osteolysis-Periodontitis-Palmoplantar Keratoderma Syndrome 0
                  Periodontal Abscess 0
                  Periodontal Pocket 0
                  acute pericementitis 0
                  aggressive periodontitis 13
                  periapical periodontitis + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.