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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:chronic kidney disease
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Accession:DOID:784 term browser browse the term
Definition:A kidney failure that is characterized by the gradual loss of kidney function. (DO)
Synonyms:exact_synonym: CKD;   CRF;   Chronic Renal Disease;   chronic kidney diseases;   chronic kidney insufficiencies;   chronic kidney insufficiency;   chronic renal diseases;   chronic renal failure;   chronic renal failure syndrome;   chronic renal insufficiencies;   chronic renal insufficiency
 primary_id: MESH:D051436
 xref: ICD10CM:N18.9;   ICD9CM:585.6;   NCI:C9438
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
chronic kidney disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Ager advanced glycosylation end product-specific receptor disease_progression
susceptibility
severity
ISO
ISS
DNA:polymorphism:promoter:g.-374T>A (human)
protein:increased expression:serum (human)
associated with Diabetes Mellitus, Type 2; DNA:polymorphism:promoter:g.-429T>C (human)
DNA:polymorphisms:promoter, intron:g.-429T>C, g.2184A>G (human)
MouseDO
RGD
PMID:23593165 PMID:21822023 PMID:21432860 PMID:20353610 PMID:20185929 RGD:7243185, RGD:7243867, RGD:7243958, RGD:7244142, RGD:7242570 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agtr1a angiotensin II receptor, type 1a disease_progression IMP
ISO
ISS
DNA:polymorphism:3' utr:1166A>C (human) MouseDO
RGD
PMID:12089373 PMID:12832734 RGD:6903863, RGD:8548869 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:12089373 RGD:6903863 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Akap12 A-kinase anchoring protein 12 susceptibility ISO
ISS
DNA:polymorphism: :rs756009(human) MouseDO
RGD
PMID:19724895 RGD:14349027 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Anln anillin, actin binding protein ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Apoa1 apolipoprotein A1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 disease_progression ISO protein:increased expression:blood plasma (human) RGD PMID:21569504 RGD:5685637 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 ISO
ISS
protein:increased expression:plasma MouseDO
RGD
PMID:21829457 PMID:21297177 RGD:7207207, RGD:7207209 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Axdnd1 axonemal dynein light chain domain containing 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:8589695 PMID:10742096 PMID:11805166 PMID:15253708 PMID:15327385 More... NCBI chr13:68,471,957...68,544,788
Ensembl chr13:68,458,411...68,544,172
JBrowse link
G Cbr1 carbonyl reductase 1 IEP mRNA, protein:decreased expression:liver RGD PMID:25332430 RGD:11565077 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,857,991...32,895,275
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Cfh complement factor H ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cfhr1 complement factor H-related 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592
JBrowse link
G Cfi complement factor I ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
JBrowse link
G Clu clusterin IEP associated with Obesity;protein:increased expression:urine RGD PMID:24325231 RGD:9068427 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col4a3 collagen type IV alpha 3 chain ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:14871398 PMID:17216251 PMID:24033266 PMID:24854265 PMID:25741868 More... NCBI chr 9:83,875,958...84,004,955
Ensembl chr 9:83,875,561...84,001,895
JBrowse link
G Col4a4 collagen type IV alpha 4 chain ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:12325029 PMID:21196518 PMID:24052634 PMID:24854265 PMID:25307543 More... NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
JBrowse link
G Cpb2 carboxypeptidase B2 ISO
ISS
DNA:polymorphism:cds :p.A147T(rs3742264)(human) MouseDO
RGD
PMID:19056482 RGD:7243119 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IEP protein:decreased expression:liver: RGD PMID:23045433 RGD:10400847 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IEP protein:decreased expression:liver: RGD PMID:23045433 RGD:10400847 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dnm1l dynamin 1-like treatment IEP RGD PMID:27801955 RGD:12738369 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dstyk dual serine/threonine and tyrosine protein kinase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Etfb electron transfer flavoprotein subunit beta ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Fgf21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:22494291 RGD:10401925 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fgf23 fibroblast growth factor 23 IEP protein:increased expression:serum: RGD PMID:20016468 RGD:10044210 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821
JBrowse link
G Fis1 fission, mitochondrial 1 treatment IEP RGD PMID:27801955 RGD:12738369 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fn1 fibronectin 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28166811 PMID:28492532 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Frem1 Fras1 related extracellular matrix 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 5:97,321,275...97,469,523
Ensembl chr 5:97,322,538...97,469,543
JBrowse link
G Ganab glucosidase II alpha subunit ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:205,793,810...205,813,701
Ensembl chr 1:205,793,895...205,813,695
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32045570 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha exacerbates ISO RGD PMID:11314805 RGD:42722629 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gpx1 glutathione peroxidase 1 treatment ISO
ISS
MouseDO
RGD
PMID:15954914 RGD:11352759 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP RGD PMID:22269876 RGD:7245952 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IEP mRNA, protein:increased expression:liver RGD PMID:12841361 RGD:1300058 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hp haptoglobin IEP protein:increased expression:serum RGD PMID:18569920 RGD:11041800 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Il19 interleukin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il1b interleukin 1 beta ISO
IDA
ISS
associated with Periodontitis; DNA:SNP:intron:g.3954C>T (human)
protein:decreased expression:serum (human)
mRNA:increased expression:kidney (mouse)
MouseDO
RGD
PMID:22795294 PMID:22728154 PMID:22613545 PMID:22398717 PMID:21975861 RGD:6906881, RGD:7175095, RGD:7175169, RGD:7175171, RGD:7175304 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO
ISS
protein:increased expression:plasma (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*1 (human)
MouseDO
RGD
PMID:23024164 PMID:22795294 RGD:6906880, RGD:6906881 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Inf2 inverted formin 2 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941
JBrowse link
G Insr insulin receptor IDA protein:decreased phosphorylation:aorta RGD PMID:22942179 RGD:7207055 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Kl Klotho treatment
disease_progression
IEP
ISO
mRNA,protein:decreased expression:renal tubule, epithelial cell:
protein:decreased expression:urine,plasma,kidney:
protein:decreased expression:urine:
RGD PMID:11967236 PMID:11967236 PMID:21115613 PMID:21115613 RGD:70544, RGD:70544, RGD:10403077, RGD:10403077 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Klk1 kallikrein 1 susceptibility ISO
ISS
associated with Vesico-Ureteral Reflux MouseDO
RGD
PMID:15086490 RGD:1581752 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Lcn2 lipocalin 2 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24714768 PMID:20921623 RGD:126781837 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lepr leptin receptor IMP RGD PMID:27465994 PMID:32390513 RGD:12911217, RGD:34888223 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:32390513 PMID:27465994 RGD:34888223, RGD:12911217
G Mfn1 mitofusin 1 treatment IEP RGD PMID:27801955 RGD:12738369 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27122239 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO
ISS
DNA:polymorphism:cds:g.677C>T (human) MouseDO
RGD
PMID:23595572 RGD:7244284 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Myh9 myosin, heavy chain 9 no_association ISO RGD PMID:22956460 RGD:12798515 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:23174956 RGD:10412711 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24244623 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility
treatment
IEP mRNA:decreased expression:cortex of kidney (rat) RGD PMID:29018182 PMID:29247650 RGD:13450920, RGD:13504713 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin severity ISO mRNA:increased expression:urine (human) RGD PMID:30133147 RGD:38549368 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:8589695 PMID:10742096 PMID:11729243 PMID:11805166 PMID:11854170 More... NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
JBrowse link
G Nppa natriuretic peptide A disease_progression ISO protein:increased expression:plasma RGD PMID:19052536 RGD:7247723 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B disease_progression ISO RGD PMID:23725445 RGD:7246908 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IDA RGD PMID:22227174 RGD:10769366 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 disease_progression IMP RGD PMID:24722447 RGD:12910103 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a1m1Mcwi nuclear receptor subfamily 4, group A, member 1; mutation 1, Medical College of Wisconsin disease_progression IMP RGD PMID:24722447 RGD:12910103
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment IEP RGD PMID:27801955 RGD:12738369 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pask PAS domain containing serine/threonine kinase ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 IDA RGD PMID:18039782 RGD:6483556 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Postn periostin ISO protein:increased secretion:urine:
protein:increased expression:kidney:
RGD PMID:22167593 PMID:22403621 RGD:10040972, RGD:10041032 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22648295 RGD:7242023 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Pth parathyroid hormone severity
treatment
ISO
IEP
IDA
ISS
associated with Diabetes Mellitus, Type 2; protein:increased expression:serum (human)
protein:decreased expression:plasma (rat)
MouseDO
RGD
PMID:23528898 PMID:23467111 PMID:23345625 PMID:21826734 PMID:22517117 RGD:7242412, RGD:7242418, RGD:7242572, RGD:7242935, RGD:7242949 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Retn resistin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22421264 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase IEP protein, activity:decreased expression:plasma, heart, kidney: RGD PMID:18299506 RGD:7327164 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
JBrowse link
G Shh sonic hedgehog signaling molecule IEP
ISO
mRNA, protein:increased expression:kidney RGD PMID:24744439 PMID:24744439 RGD:12859042, RGD:12859042 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Slc19a1 solute carrier family 19 member 1 IEP mRNA:decreased expression:multiple (rat) RGD PMID:21149507 RGD:7327184 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Slc19a2 solute carrier family 19 member 2 IEP mRNA:decreased expression:liver, heart (rat) RGD PMID:21149507 RGD:7327184 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
JBrowse link
G Slc19a3 solute carrier family 19 member 3 IEP mRNA:decreased expression:liver, heart, jejunum (rat) RGD PMID:21149507 RGD:7327184 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP
ISO
ISS
mRNA:decreased expression:kidney (rat)
DNA:snp:intron:IVS9+122A>G rs6420094 (human)
MouseDO
RGD
PMID:21826734 PMID:20383146 RGD:7242935, RGD:7243100 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852
JBrowse link
G Slc46a1 solute carrier family 46 member 1 IEP mRNA:decreased expression:liver, heart, jejunum (rat) RGD PMID:21149507 RGD:7327184 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:18784102 PMID:25741868 PMID:28492532 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Tbx18 T-box transcription factor 18 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058
JBrowse link
G Tert telomerase reverse transcriptase treatment IDA RGD PMID:23013219 RGD:11038770 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:33097957 NCBI chr13:29,733,813...29,793,870
Ensembl chr13:29,733,840...29,793,870
JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISS DNA:SNPs:promoter, exon:g.-1237T>C, g.1635G>A (rs5743836, rs352140) (human, Han Chinese) MouseDO
RGD
PMID:21908957 RGD:7246887 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 3:50,861,367...50,935,782
Ensembl chr 3:50,861,367...50,935,903
JBrowse link
G Umod uromodulin ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP
ISO
protein:increased expression:kidney
protein:increased expression:serum:
RGD PMID:20820841 PMID:21111939 RGD:4145364, RGD:7241036 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Wnt9b Wnt family member 9B ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:34145744 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Xdh xanthine dehydrogenase treatment IDA
ISO
ISS
associated with Hypertension;DNA:SNP: :66292C>G (human) MouseDO
RGD
PMID:22622455 PMID:18712049 RGD:7247640, RGD:7247654 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Zfp423 zinc finger protein 423 ISO ClinVar Annotator: match by term: Chronic kidney disease ClinVar PMID:25741868 PMID:28492532 NCBI chr19:19,111,538...19,407,371
Ensembl chr19:19,110,238...19,407,373
JBrowse link
end stage renal disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A IEP RGD PMID:17135344 RGD:2301067 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B IDA RGD PMID:17135344 RGD:2301067 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 IDA RGD PMID:17135344 RGD:2301067 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 IEP protein:decreased expression:intestine RGD PMID:17135344 RGD:2301067 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 IEP
ISO
protein:increased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:19878707 RGD:2326081 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Ace angiotensin I converting enzyme treatment
susceptibility
ISO
IMP
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Vesico-Ureteral Reflux;DNA:deletion
CTD
RGD
PMID:7593601 PMID:10099885 PMID:15118671 PMID:14586729 PMID:16385653 More... RGD:1331525, RGD:12879398, RGD:8142355, RGD:6903283 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP
ISO
protein:increased expression:serum, urine
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:24028144 RGD:8695941 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor1 adiponectin receptor 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19539174 PMID:24028144 RGD:8695941 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
JBrowse link
G Adipor2 adiponectin receptor 2 IEP RGD PMID:24028144 RGD:8695941 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO
ISS
MouseDO
RGD
PMID:9730702 RGD:7175286 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:serum (human) RGD PMID:21822023 RGD:7243867 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO
ISS
associated with Vesico-Ureteral Reflux;DNA:SNP: :-1332A>G (human) MouseDO
RGD
PMID:20149750 PMID:19212419 RGD:6903283, RGD:6903843 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Alb albumin disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11938814 PMID:11849406 RGD:11036089 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO protein:decreased expression:blood
protein:increased expression, increased glycation:plasma
associated with Hyperlipidemias
RGD PMID:22515595 PMID:18079481 PMID:20488818 RGD:7241208, RGD:7241576, RGD:7241571 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoc2 apolipoprotein C2 ISO associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:8139482 RGD:2313968 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 ISO associated with Diabetes Mellitus, Insulin-Dependent
protein:increased expression: :
RGD PMID:8139482 PMID:10822722 RGD:2313968, RGD:7207212 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E ISO protein:increased expression:serum (human) RGD PMID:21705678 PMID:21332332 RGD:6903287, RGD:6904217 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arg2 arginase 2 IEP protein:decreased activity:kidney (rat) RGD PMID:16809898 RGD:4110828 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA RGD PMID:20424483 RGD:11522730 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdkrb1 bradykinin receptor B1 resistance
no_association
ISO
ISS
DNA: SNP: G-699-->C
DNA: SNP: G(-699)C
MouseDO
RGD
PMID:9555662 PMID:10604543 PMID:10809796 RGD:7241560, RGD:7241582, RGD:7241561 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:kidney RGD PMID:24090408 RGD:11561926 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO
IEP
protein:increased expression:serum RGD PMID:20845051 PMID:17365904 RGD:7207235, RGD:7207409 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP protein:increased expression:kidney RGD PMID:24090408 RGD:11561926 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G C6 complement C6 severity IAGP RGD PMID:11912252 RGD:1600675 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G Casr calcium-sensing receptor ISO protein:decreased expression:epigastric artery (human) RGD PMID:17537980 RGD:7205455 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cat catalase IEP
ISO
protein: decreased expression :kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16518626 PMID:19420110 PMID:20007347 RGD:6892947 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 susceptibility
treatment
ISO
IDA
IEP
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-2518A>G (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:renal proximal tubule (rat)
CTD
RGD
PMID:19420110 PMID:19539174 PMID:17982227 PMID:18797164 PMID:12080327 RGD:2306990, RGD:2307007, RGD:8549739 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:22613545 RGD:7175169 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:kidney cortex (rat) RGD PMID:19535570 RGD:4889989 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO associated with Candidiasis, Invasive; RGD PMID:22916017 RGD:7241817 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:kidney cortex (rat) RGD PMID:19535570 RGD:4889989 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd2ap CD2-associated protein ISS MouseDO NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199
JBrowse link
G Cd40 CD40 molecule treatment
severity
ISO
ISS
protein:increased expression:plasma MouseDO
RGD
PMID:12941150 PMID:20846521 RGD:7248709, RGD:7248723 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:plasma RGD PMID:19019166 RGD:7248427 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd68 Cd68 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19539174 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cfb complement factor B severity ISO RGD PMID:17522263 PMID:1837062 RGD:7242704, RGD:7242753 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Chga chromogranin A ISO
ISS
protein:increased expression:serum
associated with Hypertension;DNA:polymorphisms, haplotypes:promoter, 3' utr:multiple
MouseDO
RGD
PMID:20730520 PMID:18235090 RGD:6906898, RGD:6906903 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:25782334 RGD:11041185 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO
ISS
DNA:polymorphism: :p.I1205V (human) MouseDO
RGD
PMID:19424605 RGD:7257553 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col4a3 collagen type IV alpha 3 chain ISO
ISS
MouseDO
RGD
PMID:19357112 RGD:7242047 NCBI chr 9:83,875,958...84,004,955
Ensembl chr 9:83,875,561...84,001,895
JBrowse link
G Col4a4 collagen type IV alpha 4 chain ISO
ISS
ClinVar Annotator: match by term: Stage 5 chronic kidney disease MouseDO
ClinVar
RGD
PMID:24033266 PMID:25741868 PMID:28492532 PMID:19357112 RGD:7242047 NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crp C-reactive protein disease_progression ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22865783 RGD:6906886 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf1 colony stimulating factor 1 ISO protein:increased expression:plasma RGD PMID:11340249 RGD:7257586 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO
ISS
associated with Wegener Granulomatosis;DNA:polymorphisms:promoter,exon::-318C>T, (AT)repeats (human) MouseDO
RGD
PMID:15708894 RGD:7204725 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO RGD PMID:20649681 RGD:7207863 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO
ISS
DNA:polymorphism: :1208C>T (human) MouseDO
RGD
PMID:23615182 RGD:7257672 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cyba cytochrome b-245 alpha chain IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:19420110 RGD:2306994 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:15550752 RGD:1599682 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO
ISS
IEP
DNA:polymorphisms:exon, 3' utr:3801T>C (rs4646903), p.I462V (rs1048943) (human)
mRNA, protein:decreased expression:intestine
MouseDO
RGD
PMID:23619522 PMID:12039987 RGD:7257728, RGD:7296923 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15248218 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 IEP RGD PMID:11158222 PMID:8531418 RGD:6903939, RGD:6903940 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15248218 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 ISO
ISS
DNA:polymorphisms: : MouseDO
RGD
PMID:18769365 RGD:7243146
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 IEP mRNA, protein:decreased expression:intestine RGD PMID:12039987 RGD:7296923 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddc dopa decarboxylase IEP protein:altered activity:renal cortex (rat) RGD PMID:19167406 RGD:5128880 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Drd1 dopamine receptor D1 treatment IDA RGD PMID:18402547 RGD:7248448 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 ISO
ISS
associated with Diabetes Mellitus, Non-Insulin Dependent; DNA:polymorphisms:5'utr, intron: -141delC, G>A (human) MouseDO
RGD
PMID:18366720 RGD:2311602 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Edn1 endothelin 1 IEP mRNA:increased expression:kidney (rat) RGD PMID:8441230 RGD:4144849 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO
ISS
Associated with Type 2 diabetes MouseDO
RGD
PMID:18184924 RGD:6906927 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Ephx2 epoxide hydrolase 2 disease_progression ISO RGD PMID:20694143 RGD:5688726 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:16707910 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epor erythropoietin receptor IEP protein:decreased expression:heart RGD PMID:27468524 RGD:11532749 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G F2 coagulation factor II treatment IDA RGD PMID:22473220 RGD:7387323 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V ISO
ISS
DNA:mutation: :1691G>A(human) MouseDO
RGD
PMID:19520684 RGD:6893522 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fabp1 fatty acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp2 fatty acid binding protein 2 ISO
ISS
DNA:polymorphism:CDS:amino acid A54T, associated with Diabetes Mellitus, Type 2 (MeSH:D003924) MouseDO
RGD
PMID:16249461 RGD:1578457 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fcgr2b Fc gamma receptor 2B ISO RGD PMID:15266033 RGD:7240530 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fgb fibrinogen beta chain treatment ISO
ISS
associated with hypertension;DNA:polymorphism: :-455G>A (human) MouseDO
RGD
PMID:19352213 RGD:7175505 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fn1 fibronectin 1 ISO protein:decreased expression:plasma RGD PMID:6665521 RGD:7205701 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Stage 5 chronic kidney disease
CTD
ClinVar
PMID:25741868 PMID:26970513 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gckr glucokinase regulator ISO
ISS
DNA: snp: rs1260326 MouseDO
RGD
PMID:21980298 RGD:7242279 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:18809976 RGD:7242553 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Glo1 glyoxalase 1 severity ISO
ISS
DNA:SNP: :419C>A (human) MouseDO
RGD
PMID:20185929 RGD:7242570 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:increased activity:blood:
protein:increased activity:lymphocyte:
RGD PMID:20181004 PMID:6463365 RGD:7257547, RGD:7257560 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO
ISS
MouseDO
RGD
PMID:24339523 RGD:14700960 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO
ISS
associated with Diabetes Mellitus;DNA:deletion MouseDO
RGD
PMID:15492856 RGD:2306631 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtpbp4 GTP binding protein 4 IDA RGD PMID:11316846 RGD:632611 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
JBrowse link
G Guca2b guanylate cyclase activator 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15780094 NCBI chr 5:133,246,891...133,248,941
Ensembl chr 5:133,246,909...133,248,966
JBrowse link
G Hamp hepcidin antimicrobial peptide IEP
ISO
mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
CTD
RGD
PMID:16929540 PMID:20631677 PMID:19212416 RGD:11041611, RGD:11041622 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21937979 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP
ISO
associated with Hypertension
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:21119529 RGD:5508686 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:22622455 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:kidney (rat) RGD PMID:20820841 RGD:4145364 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:10198369 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1a interleukin 1 alpha no_association ISO
ISS
DNA:SNP
DNA:SNPs, deletion, haplotypes:3' utr:multiple (human)
DNA:SNP, insertion/deletion:intron, 3' utr:rs1516792-3, rs16347-2 (human)
MouseDO
RGD
PMID:20551628 PMID:12631337 PMID:12837270 RGD:6907070, RGD:6907106, RGD:6907105 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta no_association ISO
IEP
IDA
DNA:SNP
protein:increased expression:plasma (rat)
RGD PMID:20551628 PMID:20199183 PMID:22031851 RGD:6907070, RGD:7175346, RGD:7175302 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist disease_progression
susceptibility
ISO
ISS
DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*1 (human)
protein:increased expression:serum (human)
DNA:polymorphism:exon:g.14709C>T rs315952 (human)
DNA:polymorphism:intron:IVS6+327A>G rs452204 (human)
MouseDO
RGD
PMID:17224277 PMID:16766392 PMID:16556139 PMID:12837270 PMID:20551628 RGD:6907131, RGD:6907370, RGD:6907368, RGD:6907105, RGD:6907070 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il20 interleukin 20 IEP protein:increased expression:multiple organs RGD PMID:18639518 RGD:5147394 NCBI chr13:42,380,981...42,384,625
Ensembl chr13:42,380,981...42,384,625
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19539174 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irs1 insulin receptor substrate 1 IDA protein:decreased tyrosine phosphorylation:aorta RGD PMID:22942179 RGD:7207055 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itga8 integrin subunit alpha 8 ISO
ISS
associated with Polycystic Kidney, Autosomal Dominant;DNA:polymorphism: :-414T>C(human) MouseDO
RGD
PMID:18277079 RGD:7257723 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Itgb3 integrin subunit beta 3 ISO
ISS
associated with Hypertension;DNA:polymorphism MouseDO
RGD
PMID:19368146 RGD:6907396 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 IEP protein:increased expression:renal cortex, cytosol (rat) RGD PMID:20007347 RGD:6892947 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kl Klotho ISO
IEP
mRNA,protein:decreased expression:kidney:
mRNA:decreased expression:kidney:
RGD PMID:11162628 PMID:9731228 RGD:10403042, RGD:10403067 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Klk1 kallikrein 1 ISO
ISS
MouseDO
RGD
PMID:11849458 RGD:1581753 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Lcat lecithin cholesterol acyltransferase IDA RGD PMID:15280162 RGD:1581769 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcn2 lipocalin 2 onset ISO protein:increased expression:urine: RGD PMID:22542304 RGD:7245503 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lep leptin ISO protein:increased expression:serum (human) RGD PMID:9294834 RGD:10053636 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipc lipase C, hepatic type IDA protein, mRNA:decreased expression:hepatocytes, liver (rat) RGD PMID:8636395 RGD:2308788 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipj lipase family member J ISO ClinVar Annotator: match by term: Stage 5 chronic kidney disease ClinVar PMID:28492532 NCBI chr 1:231,363,526...231,376,784
Ensembl chr 1:231,363,646...231,376,784
JBrowse link
G LOC102556347 carbonyl reductase [NADPH] 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:26282591 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Lpin1 lipin 1 IEP mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpl lipoprotein lipase IEP RGD PMID:22009636 RGD:6909179 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp2 LDL receptor related protein 2 IEP mRNA:decreased expression:kidney RGD PMID:15266031 RGD:1641836 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Mbl2 mannose binding lectin 2 ISO
ISS
associated with Lupus Erythematosus, Systemic;DNA:polymorphisms MouseDO
RGD
PMID:16801331 RGD:6903261 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mlxipl MLX interacting protein-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr12:21,542,964...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp1 matrix metallopeptidase 1 severity
no_association
ISO
ISS
DNA:insertion, haplotype:promoter:g.-1607insG (human)
DNA:insertion:promoter:g.-1607insG (human)
MouseDO
RGD
PMID:19221176 PMID:22401717 RGD:7207064, RGD:7206856 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO associated with Hypertension; protein:increased expression:plasma (human) RGD PMID:19886850 RGD:7207051 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO associated with Hypertension; protein:increased expression:plasma (human) RGD PMID:19886850 RGD:7207051 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 severity ISO
ISS
DNA:insertion, haplotype:promoter:g.-1613insA (human) MouseDO
RGD
PMID:19221176 RGD:7207064 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mpo myeloperoxidase disease_progression ISO
ISS
MouseDO
RGD
PMID:20638167 RGD:6909184 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Msr1 macrophage scavenger receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
severity
no_association
ISO
ISS
DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human)
DNA:SNP: :677C>T(human)
DNA:transitions, transversion, haplotype:cds:g.677C>T, g.1298A>C, g.1793G>A (human)
associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human)
MouseDO
RGD
PMID:19520684 PMID:25664255 PMID:17899317 PMID:14737040 PMID:19520069 RGD:6893522, RGD:14696732, RGD:6893579, RGD:6893524, RGD:6893523 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IMP RGD PMID:22427849 RGD:10040968 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myh9 myosin, heavy chain 9 ISO associated with hypertension, glomerulosclerosis, focal segmental;DNA:SNPs: :rs4821480, rs2032487, rs4821481(human)
CTD Direct Evidence: marker/mechanism
associated with diabetes mellitus, type 2;DNA:SNPs: :
DNA:SNPs:multiple:
associated with hypertension;DNA:polymorphisms:multiple:
associated with diabetes mellitus,type 2;DNA:SNPs: :
CTD
RGD
PMID:18794854 PMID:18794856 PMID:18794854 PMID:21968013 PMID:20144966 More... RGD:6903237, RGD:6903256, RGD:6903243, RGD:6903239, RGD:6903238 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Nat2 N-acetyltransferase 2 IEP mRNA,protein:decreased expression:liver: RGD PMID:20007296 RGD:11533637 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ngf nerve growth factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24244623 PMID:19169037 RGD:7242783 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos1 nitric oxide synthase 1 treatment IEP
IDA
protein:decreased expression:kidney cortex RGD PMID:17200156 PMID:23185775 RGD:1642147, RGD:7257669 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility IEP
ISS
ISO
protein:decreased expression:glomerulus
DNA:duplication, snp:intron, cds:g.IVS4?-?+27, p.E298D (human)
MouseDO
RGD
PMID:18089446 PMID:12701818 RGD:2292109, RGD:7777097 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin disease_progression IEP mRNA;increased expression:urine (rat) RGD PMID:19389856 RGD:38599006 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
JBrowse link
G Nppb natriuretic peptide B ISO protein:increased expression:plasma: RGD PMID:7606877 RGD:7246912 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppc natriuretic peptide C ISO protein:increased expression:plasma
protein:increased expression:plasma (human)
RGD PMID:8117275 PMID:8743538 RGD:1642297, RGD:1580770 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP RGD PMID:18591458 RGD:7174716 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 IEP mRNA, protein:increased expression:kidney (rat) RGD PMID:12661921 RGD:1580992 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Pax2 paired box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16631587 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pgf placental growth factor IEP RGD PMID:16543713 RGD:1642390 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Stage 5 chronic kidney disease ClinVar PMID:25741868 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO plasma:increased expression:plasma RGD PMID:16421163 RGD:7248787 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plau plasminogen activator, urokinase treatment
severity
ISO
ISS
IEP
protein:increased expression, increased activity:kidney (rat)
protein:increased expression:plasma (human)
MouseDO
RGD
PMID:19926968 PMID:15506291 PMID:17869326 PMID:22683425 RGD:6483806, RGD:7241279, RGD:7241218, RGD:7241081 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:19926968 RGD:6483806 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Postn periostin IEP mRNA,protein:increased expression,increased secretion:kidney,urine: RGD PMID:22167593 RGD:10040972 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma disease_progression ISO
ISS
associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.P12A (human) MouseDO
RGD
PMID:18467141 RGD:2301857 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment IMP RGD PMID:16871242 RGD:10003092 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19420110 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pth parathyroid hormone severity IEP
ISO
protein:increased expression:serum (rat)
protein:increased expression:serum (human)
RGD PMID:23548814 PMID:23243213 RGD:7242564, RGD:7242692 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19420110 PMID:18077597 RGD:2298859 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Retn resistin severity ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22421264 RGD:7207074 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO protein:decreased expression:plasma:
ClinVar Annotator: match by term: Stage 5 chronic kidney disease
ClinVar
RGD
PMID:28492532 PMID:15841207 RGD:7327153 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Sell selectin L no_association ISO RGD PMID:22119815 RGD:7175303 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19420110 PMID:26903149 RGD:11073683 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc22a2 solute carrier family 22 member 2 IEP protein:decreased expression:kidney, plasma membrane RGD PMID:23280877 PMID:12110012 RGD:7243177, RGD:7243883 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP mRNA:decreased expression:renal cortex (rat) RGD PMID:15452708 RGD:7242930 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852
JBrowse link
G Slc9a5 solute carrier family 9 member A5 resistance ISO
ISS
DNA:polymorphism MouseDO
RGD
PMID:10642288 RGD:1643221 NCBI chr19:33,225,481...33,246,913
Ensembl chr19:33,226,816...33,246,903
JBrowse link
G Soat2 sterol O-acyltransferase 2 IDA RGD PMID:12217884 RGD:625687 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878707 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 IEP
ISO
mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19878707 PMID:16814791 RGD:2308825 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Tbx21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26970513 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP
ISO
mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19420110 PMID:10919844 RGD:7394838 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thbd thrombomodulin ISO protein:increased expression:plasma RGD PMID:22129968 PMID:21873362 RGD:5684979, RGD:5684981 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:20729266 RGD:7240546 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:20729266 RGD:7240546 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19539174 PMID:22266663 RGD:7245510 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B severity ISO RGD PMID:21479768 RGD:7205485 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:22266663 RGD:7245510 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:22266663 RGD:7245510 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Ucp2 uncoupling protein 2 susceptibility ISO
ISS
DNA:polymorphism: :-866G>A (human)
DNA:deletion
MouseDO
RGD
PMID:19406964 PMID:18242170 RGD:7175298, RGD:7175299 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vwf von Willebrand factor disease_progression
treatment
ISO
ISS
protein:increased oxidation:plasma MouseDO
RGD
PMID:22189209 PMID:21378155 PMID:22091998 RGD:7205641, RGD:7205649, RGD:7205646 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
Frasier syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Frasier syndrome OMIM
ClinVar
PMID:1302008 PMID:1658787 PMID:7795587 PMID:8388765 PMID:9108089 More... NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
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Term paths to the root
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Term Annotations click to browse term
  disease 18145
    disease of anatomical entity 17519
      Urogenital Diseases 4704
        urinary system disease 2389
          kidney disease 2161
            kidney failure 508
              chronic kidney disease 245
                end stage renal disease + 178
paths to the root