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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:diverticulitis
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Accession:DOID:7475 term browser browse the term
Definition:An intestinal disease characterized by the formation and inflammation of diverticula within the bowel wall. (DO)
Synonyms:exact_synonym: diverticulitides
 primary_id: MESH:D004238
 xref: EFO:1001460;   NCI:C26752
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
diverticulitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nalf1 NALCN channel auxiliary factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28585551 NCBI chr16:79,713,577...80,236,295
Ensembl chr16:79,713,724...80,235,120 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO mRNA:decreased expression:colonic mucosa (human) RGD PMID:18491196 RGD:38549586 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
diverticulitis of colon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd163 CD163 molecule exacerbates ISO protein:increased expression:sigmoid colon (human) RGD PMID:21553154 RGD:40925945 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd68 Cd68 molecule severity ISO associated with steroid use;protein:increased expression:sigmoid colon (human) RGD PMID:21553154 RGD:40925945 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19065
    disease by infectious agent 2248
      Intraabdominal Infections 45
        diverticulitis 4
          Meckel's diverticulitis 0
          diverticulitis of colon 2
          small intestine diverticulitis 0
Path 2
Term Annotations click to browse term
  disease 19065
    Pathological Conditions, Signs and Symptoms 13511
      Pathologic Processes 8221
        Inflammation 2815
          gastroenteritis 566
            diverticulitis 4
              Meckel's diverticulitis 0
              diverticulitis of colon 2
              small intestine diverticulitis 0
paths to the root