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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:monoclonal gammopathy of uncertain significance
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Accession:DOID:7442 term browser browse the term
Definition:A blood protein disease that is characterized by the presence of an abnormal protein called monoclonal protein in the blood. (DO)
Synonyms:exact_synonym: MGUS;   benign monoclonal gammopathies;   benign monoclonal gammopathy;   monoclonal gammopathy of undetermined significance
 xref: EFO:0000203;   EFO:1000836;   GARD:7034;   MESH:D008998;   MONDO:0004225;   NCI:C3996
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
monoclonal gammopathy of uncertain significance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:microsatellite polymorphism:exon: : RGD PMID:11167807 RGD:11352247 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISS MouseDO NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Nefh neurofilament heavy chain ISO associated with Peripheral Nervous System Diseases RGD PMID:12536221 RGD:9693726 NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417 		JBrowse link
Schnitzler syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha ISO RGD PMID:1831824 RGD:7794711 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:16096327 PMID:16096327 RGD:11522758 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19167
    Pathological Conditions, Signs and Symptoms 13667
      Signs and Symptoms 11198
        Hypergammaglobulinemia 20
          monoclonal gammopathy of uncertain significance 5
            Schnitzler syndrome 2
Path 2
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 18473
      Immune & Inflammatory Diseases 5781
        immune system disease 5094
          Immunoproliferative Disorders 1158
            lymphoproliferative syndrome 1150
              lymphoma 580
                non-Hodgkin lymphoma 488
                  B-cell lymphoma 344
                    mature B-cell neoplasm 196
                      plasma cell neoplasm 174
                        monoclonal gammopathy of uncertain significance 5
                          Schnitzler syndrome 2
paths to the root