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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:anthrax disease
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Accession:DOID:7427 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath. (DO)
Synonyms:exact_synonym: anthrax
 primary_id: MESH:D000881
 xref: EFO:0000778;   GARD:8157;   ICD10CM:A22;   ICD9CM:022;   NCI:C84565
For additional species annotation, visit the Alliance of Genome Resources.

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anthrax disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Antxr2 ANTXR cell adhesion molecule 2 ISO RGD PMID:17054395 RGD:1599126 NCBI chrNW_004624757:10,972,976...11,123,103
Ensembl chrNW_004624757:10,972,692...11,125,898 		JBrowse link
G Il1b interleukin 1 beta disease_progression ISO mRNA:decreased expression:multiple (mouse) RGD PMID:19075243 RGD:40902812 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
G LOC101715199 neutrophil elastase ISO protein:increased expression:plasma: RGD PMID:19049643 RGD:10450550 NCBI chrNW_004624828:7,720,020...7,722,842 JBrowse link
G Rnasel ribonuclease L severity ISO RGD PMID:19075243 RGD:40902812 NCBI chrNW_004624814:11,268,725...11,319,023
Ensembl chrNW_004624814:11,268,698...11,305,221 		JBrowse link
G Tnf tumor necrosis factor disease_progression ISO protein:decreased expression:multiple (mouse) RGD PMID:19075243 RGD:40902812 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
inhalation anthrax term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl10 C-X-C motif chemokine ligand 10 disease_progression ISO RGD PMID:21124994 RGD:5135283 NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 disease_progression ISO RGD PMID:21124994 RGD:5135283 NCBI chrNW_004624757:14,952,966...14,954,343
Ensembl chrNW_004624757:14,952,851...14,954,905 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 disease_progression ISO RGD PMID:21124994 RGD:5135283 NCBI chrNW_004624757:14,995,649...15,009,771
Ensembl chrNW_004624757:14,995,716...15,011,893 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14229
    disease by infectious agent 1935
      Bacterial Infections and Mycoses 960
        bacterial infectious disease 722
          primary bacterial infectious disease 160
            anthrax disease 8
              cutaneous anthrax 0
              gastrointestinal anthrax + 0
              inhalation anthrax 3
              injection anthrax 0
Path 2
Term Annotations click to browse term
  disease 14229
    disease by infectious agent 1935
      Bacterial Infections and Mycoses 960
        bacterial infectious disease 722
          Gram-Positive Bacterial Infections 344
            Bacillaceae Infections 8
              anthrax disease 8
                cutaneous anthrax 0
                gastrointestinal anthrax + 0
                inhalation anthrax 3
                injection anthrax 0
paths to the root