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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:anthrax disease
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Accession:DOID:7427 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath. (DO)
Synonyms:exact_synonym: anthrax
 primary_id: MESH:D000881
 xref: EFO:0000778;   GARD:8157;   ICD10CM:A22;   ICD9CM:022;   NCI:C84565
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
anthrax disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTXR2 ANTXR cell adhesion molecule 2 ISO RGD PMID:17054395 RGD:1599126 NCBI chr32:4,143,407...4,302,194
Ensembl chr32:4,148,310...4,302,071 		JBrowse link
G ELANE elastase, neutrophil expressed ISO protein:increased expression:plasma: RGD PMID:19049643 RGD:10450550 NCBI chr20:57,789,044...57,790,932
Ensembl chr20:57,788,062...57,790,932 		JBrowse link
G IL1B interleukin 1 beta disease_progression ISO mRNA:decreased expression:multiple (mouse) RGD PMID:19075243 RGD:40902812 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G RNASEL ribonuclease L severity ISO RGD PMID:19075243 RGD:40902812 NCBI chr 7:15,978,055...16,001,604
Ensembl chr 7:15,856,151...16,001,569 		JBrowse link
G TNF tumor necrosis factor disease_progression ISO protein:decreased expression:multiple (mouse) RGD PMID:19075243 RGD:40902812 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
inhalation anthrax term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL10 C-X-C motif chemokine ligand 10 disease_progression ISO RGD PMID:21124994 RGD:5135283 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 disease_progression ISO RGD PMID:21124994 RGD:5135283 NCBI chr32:631,084...636,997
Ensembl chr32:631,478...632,868
Ensembl chr32:631,478...632,868 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15753
    disease by infectious agent 2165
      Bacterial Infections and Mycoses 1053
        bacterial infectious disease 798
          primary bacterial infectious disease 183
            anthrax disease 7
              cutaneous anthrax 0
              gastrointestinal anthrax + 0
              inhalation anthrax 2
              injection anthrax 0
Path 2
Term Annotations click to browse term
  disease 15753
    disease by infectious agent 2165
      Bacterial Infections and Mycoses 1053
        bacterial infectious disease 798
          Gram-Positive Bacterial Infections 390
            Bacillaceae Infections 7
              anthrax disease 7
                cutaneous anthrax 0
                gastrointestinal anthrax + 0
                inhalation anthrax 2
                injection anthrax 0
paths to the root