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ONTOLOGY REPORT - ANNOTATIONS


Term:autoimmune thyroiditis
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Accession:DOID:7188 term browser browse the term
Definition:Inflammatory disease of the THYROID GLAND due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-CELLS and thyroid AUTOANTIBODIES. The clinical signs can range from HYPOTHYROIDISM to THYROTOXICOSIS depending on the type of autoimmune thyroiditis.
Synonyms:exact_synonym: Hashimoto thyroiditis;   Hashimoto's thyroiditis;   autoimmune thyroiditides;   chronic lymphocytic thyroiditis;   lymphocytic thyroiditides;   lymphocytic thyroiditis;   lymphomatous thyroiditides;   lymphomatous thyroiditis
 related_synonym: AITD1;   AITD2;   AITD3;   AITD4;   AUTOIMMUNE THYROID DISEASE, SUSCEPTIBILITY TO, 1;   AUTOIMMUNE THYROID DISEASE, SUSCEPTIBILITY TO, 2;   AUTOIMMUNE THYROID DISEASE, SUSCEPTIBILITY TO, 3;   AUTOIMMUNE THYROID DISEASE, SUSCEPTIBILITY TO, 4
 primary_id: MESH:D013967
 alt_id: OMIM:608173;   OMIM:608174;   OMIM:608175;   OMIM:608176;   RDO:0006698
 xref: ICD10CM:E06.3;   NCI:C38766
For additional species annotation, visit the Alliance of Genome Resources.


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autoimmune thyroiditis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bank1 B-cell scaffold protein with ankyrin repeats 1 JBrowse link 2 241,273,763 241,545,527 RGD:9684981
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:10058966
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:2302003
RGD:8554872
RGD:7421515
RGD:1300386
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:7349390
G Gjb1 gap junction protein, beta 1 JBrowse link X 71,272,030 71,279,973 RGD:7349390
G Gjb2 gap junction protein, beta 2 JBrowse link 15 37,377,313 37,394,494 RGD:7349390
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:10755769
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:4841878
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:8142396
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2307256
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:1641847
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:8693703
RGD:14696815
G Psmb9 proteasome 20S subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:6483439
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:6484667
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:2301816
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147571
G RT1-Da RT1 class II, locus Da JBrowse link 20 4,127,644 4,132,616 RGD:5147805
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147557
RGD:5147805
RGD:5147571
G Tg thyroglobulin JBrowse link 7 107,467,260 107,652,897 RGD:5147557
RGD:8554872
RGD:7240710
RGD:11554173
RGD:8548629
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:5128798
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4841878
G Tshr thyroid stimulating hormone receptor JBrowse link 6 115,170,290 115,306,871 RGD:11554173
G Zfat zinc finger and AT hook domain containing JBrowse link 7 109,037,777 109,207,511 RGD:8554872
RGD:11554173
RGD:7240710
Autoimmune Hypothyroidism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:8554872
Hashimoto Disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bank1 B-cell scaffold protein with ankyrin repeats 1 JBrowse link 2 241,273,763 241,545,527 RGD:9684981
G C1s complement C1s JBrowse link 4 157,143,592 157,155,592 RGD:11554173
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:9068926
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:8547767
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:8547767
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:7240710
RGD:8554872
RGD:7421513
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:10045850
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:8662824
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:12910543
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8547592
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8142375
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:7829719
RGD:11554173
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:11554173
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:8693703
G Psmb9 proteasome 20S subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:6483332
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:6484548
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:5147613
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147613
RGD:7483569
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147613
G Tg thyroglobulin JBrowse link 7 107,467,260 107,652,897 RGD:8548606
RGD:11554173
RGD:8548647
RGD:8548630
RGD:8548607
G Tnfrsf8 TNF receptor superfamily member 8 JBrowse link 5 163,186,349 163,231,578 RGD:11554173
G Tnfsf8 TNF superfamily member 8 JBrowse link 5 79,664,779 79,691,547 RGD:11554173
G Tshr thyroid stimulating hormone receptor JBrowse link 6 115,170,290 115,306,871 RGD:8548662

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16017
    disease of anatomical entity 15273
      endocrine system disease 4932
        autoimmune disease of endocrine system 94
          autoimmune thyroiditis 36
            Autoimmune Hypothyroidism 1
            Hashimoto Disease + 23
            Postpartum Thyroiditis 0
Path 2
Term Annotations click to browse term
  disease 16017
    disease of anatomical entity 15273
      Immune & Inflammatory Diseases 3417
        immune system disease 2804
          hypersensitivity reaction disease 1529
            autoimmune hypersensitivity disease 1224
              autoimmune disease of endocrine system 94
                autoimmune thyroiditis 36
                  Autoimmune Hypothyroidism 1
                  Hashimoto Disease + 23
                  Postpartum Thyroiditis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.