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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:rheumatoid arthritis
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Accession:DOID:7148 term browser browse the term
Definition:An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (DO)
Synonyms:exact_synonym: RA;   atrophic arthritis;   rheumatic arthritis or polyarthritis
 narrow_synonym: ACPA-negative rheumatoid arthritis;   ACPA-positive rheumatoid arthritis;   CD244-RELATED CONDITION;   RHEUMATOID ARTHRITIS, PROGRESSION OF;   SLC22A4-RELATED CONDITION
 related_synonym: rheumatoid arthritis, susceptibility to
 primary_id: MESH:D001172
 alt_id: MIM:180300
 xref: EFO:0000685;   EFO:0009459;   EFO:0009460;   ICD10CM:M06.9;   ICD9CM:714.0;   NCI:C2884
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20080907 PMID:22104130 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr14:110,955,698...111,038,898
Ensembl chr14:110,955,582...111,038,898 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr12:26,920,764...26,978,389
Ensembl chr12:26,920,821...26,979,602 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr11:64,089,149...64,309,831 JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr13:121,868,614...121,957,901
Ensembl chr13:121,869,600...121,926,071 		JBrowse link
G ABCG2A ATP binding cassette subfamily G member 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 8:130,853,414...130,945,388
Ensembl chr 8:130,775,444...130,945,393 		JBrowse link
G ACAN aggrecan disease_progression ISO protein:increased degradation:cartilage
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15292528 PMID:16507130 RGD:11570537 NCBI chr 7:54,449,830...54,520,606
Ensembl chr 7:54,449,816...54,519,194 		JBrowse link
G ACKR3 atypical chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr15:136,370,457...136,382,559
Ensembl chr15:136,370,530...136,382,553 		JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 ISO mRNA:increased expression:synovium RGD PMID:11801682 RGD:10043106 NCBI chr 4:89,260,354...89,269,238
Ensembl chr 4:89,260,461...89,269,244 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO protein:alternative form:synovium RGD PMID:11801682 RGD:10043106 NCBI chr13:190,353,019...190,413,110
Ensembl chr13:190,361,744...190,413,110 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12833524 PMID:21789720 RGD:5686424 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ADORA2A adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr14:49,467,186...49,485,845
Ensembl chr14:49,468,877...49,485,850 		JBrowse link
G ADRB3 adrenoceptor beta 3 ISO DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:12739037 RGD:5684893 NCBI chr15:48,468,803...48,478,370
Ensembl chr15:48,475,144...48,479,562 		JBrowse link
G AFF3 ALF transcription elongation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 3:54,135,476...54,730,201
Ensembl chr 3:54,135,532...54,727,885 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:decreased expression:plasma (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16385501 PMID:20541603 RGD:7244141 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18617548 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,019...90,907,090 		JBrowse link
G AMCF-II alveolar macrophage-derived chemotactic factor-II ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 8:70,008,225...70,010,360
Ensembl chr 8:70,008,162...70,010,358 		JBrowse link
G ANG angiogenin ISO RGD PMID:12653852 RGD:6892721 NCBI chr 7:78,249,479...78,262,846
Ensembl chr 7:78,249,487...78,250,138 		JBrowse link
G ANKRD55 ankyrin repeat domain 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr16:35,231,670...35,662,787
Ensembl chr16:35,231,673...35,330,790 		JBrowse link
G ANXA3 annexin A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 8:73,970,314...73,993,039 JBrowse link
G APOA4 apolipoprotein A4 ISO protein:increased expression:blood serum (human) RGD PMID:20367977 RGD:5685646 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G ARID5B AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 PMID:23143596 NCBI chr14:65,408,603...65,598,485
Ensembl chr14:65,408,598...65,598,485 		JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19193698 NCBI chr15:117,617,584...117,649,063
Ensembl chr15:117,617,502...117,649,107 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA:decreased expression:liver RGD PMID:18372237 RGD:153352318 NCBI chr 3:7,867,521...7,874,857 JBrowse link
G B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 3:79,671,393...79,704,049
Ensembl chr 3:79,670,748...79,704,000 		JBrowse link
G B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 6:27,791,387...27,797,458
Ensembl chr 6:27,792,134...27,795,361 		JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 3:5,472,305...5,567,926
Ensembl chr 3:5,472,315...5,567,876 		JBrowse link
G BCL2A1 BCL2 related protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 7:48,887,227...48,897,667
Ensembl chr 7:48,887,094...48,897,870 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,713...117,472,005 		JBrowse link
G BGN biglycan ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr  X:124,282,048...124,295,450
Ensembl chr  X:124,275,305...124,295,445 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,943...14,745,947 		JBrowse link
G BMP4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270 		JBrowse link
G BTNL2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : RGD PMID:23364395 RGD:9685033 NCBI chr 7:24,789,988...24,809,920
Ensembl chr 7:24,789,888...24,810,132 		JBrowse link
G C3 complement C3 ISO RGD PMID:7561187 RGD:11040775 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228 		JBrowse link
G C4A complement C4A (Rodgers blood group) ISO RGD PMID:22076784 RGD:5688263 NCBI chr 7:24,068,019...24,083,060
Ensembl chr 7:24,068,013...24,083,065 		JBrowse link
G CA1 carbonic anhydrase 1 ISO RGD PMID:12806141 RGD:408425977 NCBI chr 4:51,343,548...51,353,127
Ensembl chr 4:51,302,406...51,353,126 		JBrowse link
G CA2 carbonic anhydrase 2 ISO RGD PMID:12806141 RGD:408425977 NCBI chr 4:51,194,686...51,211,436
Ensembl chr 4:51,193,756...51,211,259 		JBrowse link
G CALD1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:18785314 RGD:5684540 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,019,164...124,050,365 		JBrowse link
G CAST calpastatin ISO RGD PMID:7706496 RGD:5683620 NCBI chr 2:103,255,738...103,378,623
Ensembl chr 2:103,255,750...103,378,623 		JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CAV2 caveolin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr18:29,699,012...29,707,277
Ensembl chr18:29,699,020...29,707,277 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO protein:increased expression:serum RGD PMID:20056091 RGD:4891442 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chr10:32,093,783...32,094,482
Ensembl chr10:32,093,763...32,096,224 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr 6:19,296,726...19,301,506
Ensembl chr 6:19,296,637...19,302,737 		JBrowse link
G CCL8 chemokine (C-C motif) ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr12:40,740,468...40,741,970
Ensembl chr12:40,740,023...40,742,022 		JBrowse link
G CCN1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (human)		 CTD
RGD		 PMID:19192274 PMID:34031328 RGD:329845561 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,407...130,395,150 		JBrowse link
G CCN2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,674,394...31,677,691 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:12860725 RGD:5688170 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,285,012...29,286,467 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:synovium:
protein:increased expression:synovial membrane:		 RGD PMID:19942450 PMID:25430645 RGD:10054497 RGD:10054499 NCBI chr13:18,860,596...18,865,987
Ensembl chr13:18,860,730...18,865,983 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 resistance
no_association		 ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:16541097 PMID:17565662 RGD:1626283 RGD:1626290 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453841 PMID:20453842 PMID:23143596 NCBI chr 1:2,016,600...2,034,172
Ensembl chr 1:2,018,608...2,019,821 		JBrowse link
G CD2 CD2 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 4:103,963,802...103,976,971
Ensembl chr 4:103,963,345...103,977,292 		JBrowse link
G CD244 CD244 molecule susceptibility ISO ClinVar Annotator: match by term: CD244-related condition | ClinVar Annotator: match by term: Rheumatoid arthritis OMIM
ClinVar		 PMID:18794858 PMID:25741868 PMID:28492532 NCBI chr 4:89,668,221...89,700,974
Ensembl chr 4:89,668,239...89,700,972 		JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19075187 PMID:19898481 PMID:20453842 PMID:23143596 RGD:5131619 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,203...107,162,935 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 9:45,619,730...45,633,972
Ensembl chr 9:45,619,482...45,633,968 		JBrowse link
G CD40 CD40 molecule ISO DNA:SNP: :rs4810485 (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18794853 PMID:20453842 PMID:20498205 PMID:23143596 RGD:5490972 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CD5 CD5 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 2:10,648,973...10,673,479
Ensembl chr 2:10,648,974...10,673,919 		JBrowse link
G CD80 CD80 molecule ISO protein:increased expression:serum RGD PMID:22917707 RGD:6893647 NCBI chr13:140,693,312...140,730,541
Ensembl chr13:140,693,382...140,728,976 		JBrowse link
G CD83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 7:10,346,122...10,385,968
Ensembl chr 7:10,359,211...10,385,961 		JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 NCBI chr 9:72,510,858...72,765,631
Ensembl chr 9:72,518,101...72,764,129 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO protein:increased expression:knee, articular cartilage (human) RGD PMID:19248099 RGD:10401213 NCBI chr17:51,722,633...51,723,673
Ensembl chr17:51,722,426...51,724,305 		JBrowse link
G CHI3L1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:10461474 RGD:4892605 NCBI chr 9:113,885,541...113,895,033
Ensembl chr 9:113,885,542...113,895,131 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO mRNA,protein:increased expression:joint, spleen: RGD PMID:31279484 RGD:151676715 NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123 		JBrowse link
G CHRNG cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:23261301 PMID:25741868 PMID:28492532 NCBI chr15:133,051,668...133,059,935
Ensembl chr15:133,052,031...133,058,544 		JBrowse link
G CIITA class II major histocompatibility complex transactivator no_association
susceptibility		 ISO DNA:polymorphism:promoter:rs3087456, no association in a German cohort
DNA:polymorphism:promoter:-168A>G
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis		 RGD
OMIM
ClinVar		 PMID:8402893 PMID:9099848 PMID:15821736 PMID:16199547 PMID:16426246 More... RGD:1358146 RGD:5491189 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780 		JBrowse link
G CLEC12A C-type lectin domain family 12 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 5:61,923,057...61,936,843
Ensembl chr 5:61,922,895...61,937,096 		JBrowse link
G CLEC16A C-type lectin domain containing 16A ISO DNA:polymorphism:intron:rs6498169G RGD PMID:19221398 RGD:5491176 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,320 		JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:27028940 PMID:29935983 NCBI chr 5:78,350,131...78,380,893
Ensembl chr 5:78,350,137...78,380,718 		JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr13:89,396,713...89,463,540
Ensembl chr13:89,396,708...89,463,476 		JBrowse link
G CRP C-reactive protein, pentraxin-related ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 RGD
CTD		 PMID:1568518 PMID:22173958 RGD:6904209 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218 		JBrowse link
G CSF2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103 		JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 2:1,188,548...1,197,642
Ensembl chr 2:1,188,549...1,197,643 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:11465708 RGD:4892002 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G CXCL2 chemokine (C-X-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 8:70,157,253...70,159,145
Ensembl chr 8:70,157,214...70,159,138 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:19192274 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr  X:57,592,032...57,595,706
Ensembl chr  X:57,592,038...57,595,692 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232 		JBrowse link
G CYBB cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:24313545 NCBI chr  X:33,654,656...33,678,346
Ensembl chr  X:33,643,648...33,680,580 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr14:75,117,708...75,119,907
Ensembl chr14:75,117,710...75,119,902 		JBrowse link
G DDX6 DEAD-box helicase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 9:46,025,616...46,063,836
Ensembl chr 9:46,025,625...46,063,818 		JBrowse link
G DHFR dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chr13:39,958,384...39,976,114
Ensembl chr13:39,958,387...39,975,946 		JBrowse link
G DNASE2 deoxyribonuclease 2, lysosomal ISO OMIM:180300 MouseDO NCBI chr 2:66,150,071...66,152,857
Ensembl chr 2:66,149,862...66,152,855 		JBrowse link
G DNMT1 DNA methyltransferase 1 severity ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression ISO DNA:polymorphism:promoter:-283C>T(human) RGD PMID:19777235 RGD:9589110 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072 		JBrowse link
G EDN1 endothelin 1 treatment ISO RGD PMID:22249931 RGD:8661695 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G ELN elastin ISO RGD PMID:12643515 RGD:9585739 NCBI chr 3:11,214,194...11,245,891
Ensembl chr 3:11,214,205...11,244,897 		JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898480 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,816...94,254,079 		JBrowse link
G ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 ISO mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:36104638 RGD:155791669 NCBI chr14:11,495,297...11,532,898 JBrowse link
G ESR2 estrogen receptor 2 severity ISO DNA:SNP:exon:rs1256049(human) RGD PMID:21523342 RGD:5508794 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565 		JBrowse link
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G FAS Fas cell surface death receptor susceptibility ISO DNA:snp:promoter:g.-670A>G (human)
protein:increased expression:serum (human)		 RGD PMID:12148596 PMID:20875116 PMID:23053964 RGD:12903969 RGD:8662433 RGD:8662455 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G FASLG Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464 		JBrowse link
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) ISO protein:increased expression:synovial joint: RGD PMID:16670289 RGD:9685708 NCBI chr 4:99,233,632...99,242,531
Ensembl chr 4:99,233,611...99,242,586 		JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human)
DNA:CNVs
protein:decreased expression:NK cell		 RGD PMID:15334114 PMID:19019892 PMID:25154742 RGD:11344974 RGD:5508391 RGD:5508467 NCBI chr 4:88,948,357...88,956,513 JBrowse link
G FKBP5 FKBP prolyl isomerase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 7:31,441,764...31,550,704
Ensembl chr 7:31,440,842...31,567,487 		JBrowse link
G FOXO3 forkhead box O3 ISO mRNA,protein:increased expression:peripheral blood mononuclear cell, polymorphonuclear cell,synovium: RGD PMID:19435720 RGD:10402186 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325 		JBrowse link
G FOXP3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20476861 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G FPGS folylpolyglutamate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 1:268,281,298...268,309,397
Ensembl chr 1:268,287,765...268,309,398 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr13:197,130,898...197,158,797
Ensembl chr13:197,130,904...197,161,891 		JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859 		JBrowse link
G GC GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma		 CTD
RGD		 PMID:3874814 PMID:9548303 RGD:5509931 NCBI chr 8:68,326,293...68,360,262
Ensembl chr 8:68,326,299...68,360,262 		JBrowse link
G GDF5 growth differentiation factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18830904 NCBI chr17:38,792,854...38,796,806
Ensembl chr17:38,792,187...38,797,005 		JBrowse link
G GGH gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 4:70,996,730...71,020,513
Ensembl chr 4:70,996,755...71,021,838 		JBrowse link
G GIN1 gypsy retrotransposon integrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 2:108,561,132...108,599,017
Ensembl chr 2:108,561,387...108,597,262 		JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 5:59,565,793...59,586,641
Ensembl chr 5:59,565,799...59,586,600 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO protein: decreased expression: mononuclear leukocytes
DNA: deletion: : heterozygous
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10094932 PMID:18662895 RGD:5688373 RGD:5688380 NCBI chr 2:5,209,435...5,227,543
Ensembl chr 2:5,209,439...5,227,758 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 no_association ISO protein: : mononuclear blood cells
DNA: deletion::GRK2 and GRK6 deletions resulted in more severe arthritis		 RGD PMID:10094932 PMID:18662895 RGD:5688373 RGD:5688380 NCBI chr14:129,113,933...129,351,135
Ensembl chr14:129,113,603...129,347,152 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO protein: decreased expression: mononuclear leukocytes
DNA: deletion: : homozygous
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10094932 PMID:18662895 RGD:5688373 RGD:5688380 NCBI chr 2:80,496,105...80,527,208
Ensembl chr 2:80,508,979...80,527,210 		JBrowse link
G GSDME gasdermin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr18:47,524,637...47,583,748
Ensembl chr18:47,526,797...47,583,731 		JBrowse link
G HAPLN1 hyaluronan and proteoglycan link protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:91,857,495...91,935,485
Ensembl chr 2:91,857,582...91,907,351 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,144...138,889,281 		JBrowse link
G HDAC1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289289 NCBI chr 6:88,749,611...88,785,220
Ensembl chr 6:88,749,634...88,785,411 		JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HGF hepatocyte growth factor disease_progression ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO RGD PMID:18025202 RGD:9685481 NCBI chr18:46,205,164...46,215,861
Ensembl chr18:46,205,418...46,215,856 		JBrowse link
G HOXD10 homeobox D10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr15:81,911,372...81,921,164
Ensembl chr15:81,917,637...81,921,461 		JBrowse link
G HOXD11 homeobox D11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr15:81,906,654...81,910,765
Ensembl chr15:81,908,460...81,911,282 		JBrowse link
G HOXD13 homeobox D13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr15:81,893,997...81,897,965
Ensembl chr15:81,893,972...81,896,944 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:133,231,451...133,278,396
Ensembl chr 9:133,231,451...133,278,396 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:peripheral blood lymphocyte (human) RGD PMID:22047640 RGD:5688784 NCBI chr 2:135,345,724...135,391,112
Ensembl chr 2:135,345,867...135,391,108 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression:synovial joint RGD PMID:11315915 RGD:5685639 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO protein:increased expression:synovial cell: RGD PMID:23739258 RGD:10402561 NCBI chr 2:140,515,239...140,532,164
Ensembl chr 2:140,515,253...140,531,857 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO protein:increased expression:serum: RGD PMID:21417552 RGD:10402843 NCBI chr 3:10,038,074...10,039,441
Ensembl chr 3:10,037,949...10,039,704 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G IFNG interferon gamma treatment ISO mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:1417133 PMID:22450443 PMID:22660635 RGD:155663483 RGD:8157623 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IGF2 insulin like growth factor 2 ISO DNA:loss of imprinting:synovial cell
protein:decreased expression:plasma		 RGD PMID:11247331 PMID:19556211 RGD:5510001 RGD:5510014 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr18:50,002,921...50,009,425
Ensembl chr18:50,003,022...50,010,690 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr12:22,466,386...22,562,320
Ensembl chr12:22,466,414...22,562,312 		JBrowse link
G IL10 interleukin 10 ISO ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis, progression of ClinVar
OMIM		 PMID:12847677 PMID:25741868 PMID:28492532 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093 		JBrowse link
G IL17A interleukin 17A treatment ISO mRNA:increased expression:synovial (human) RGD PMID:20926833 PMID:22660635 RGD:155663483 RGD:9068415 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16368150 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL19 interleukin 19 ISO ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis, progression of ClinVar PMID:12847677 PMID:25741868 PMID:28492532 NCBI chr 9:67,469,519...67,479,597
Ensembl chr 9:67,469,524...67,479,813 		JBrowse link
G IL1A interleukin 1 alpha severity ISO protein:increased expression:plasma, synovial fluid
associated with lung disease, interstitial		 RGD PMID:8162643 PMID:11192540 RGD:4142818 RGD:7794716 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD		 PMID:7706905 PMID:10637275 PMID:19192274 PMID:19447938 RGD:7174696 RGD:8549810
G IL2 interleukin 2 ISO RGD PMID:6421522 RGD:8662948 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL20 interleukin 20 ISO RGD PMID:16947773 RGD:5147395 NCBI chr 9:67,498,788...67,502,110
Ensembl chr 9:67,498,813...67,502,096 		JBrowse link
G IL21R interleukin 21 receptor ISO RGD PMID:19342640 RGD:6892964 NCBI chr 3:19,447,488...19,489,201
Ensembl chr 3:19,443,359...19,489,152 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G IL23R interleukin 23 receptor susceptibility ISO DNA:SNP::rs1343151(human) RGD PMID:18647855 RGD:8549596 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:20476861 PMID:23143596 NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,563...65,001,142 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 5:10,610,094...10,650,315
Ensembl chr 5:10,628,962...10,650,314 		JBrowse link
G IL4R interleukin 4 receptor severity ISO DNA:SNP: :rs1805010 (human) RGD PMID:24782180 RGD:10402783 NCBI chr 3:19,526,343...19,576,792
Ensembl chr 3:19,523,564...19,576,544 		JBrowse link
G IL5 interleukin 5 ISO RGD PMID:22293286 RGD:5687156 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212 		JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 PMID:22450443 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16729287 PMID:23143596 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,433...95,381,282 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism
OMIM:180300		 CTD
MouseDO		 PMID:20453842 NCBI chr16:35,101,304...35,151,832
Ensembl chr16:35,101,306...35,192,220 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860 		JBrowse link
G IRF5 interferon regulatory factor 5 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:15657875 PMID:16642019 PMID:17599733 PMID:18063667 NCBI chr18:19,678,377...19,691,154
Ensembl chr18:19,678,687...19,691,243 		JBrowse link
G IRF8 interferon regulatory factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 6:3,041,617...3,060,685
Ensembl chr 6:3,041,645...3,097,406 		JBrowse link
G ITGA6 integrin subunit alpha 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr15:78,504,108...78,591,779
Ensembl chr15:78,504,078...78,591,777 		JBrowse link
G ITPA inosine triphosphatase treatment ISO DNA:SNP: :94C>A(human) RGD PMID:29441893 RGD:14975307 NCBI chr17:32,458,351...32,474,827
Ensembl chr17:32,455,459...32,474,784 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21510883 RGD:6483024 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G KAT2B lysine acetyltransferase 2B ISO mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:36104638 RGD:155791669 NCBI chr13:6,985,151...7,099,771
Ensembl chr13:6,985,235...7,100,345 		JBrowse link
G KIF5A kinesin family member 5A susceptibility ISO DNA:snps:intron, 3' utr:c.2756-43A>C, c.*776C>T (rs775246, rs775251) (human)
DNA:snp:intron:c.1717-152C>G (rs1678542) (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:21784728 PMID:23143596 PMID:23378462 RGD:12793072 RGD:12793073 NCBI chr 5:22,813,617...22,851,976
Ensembl chr 5:22,816,854...22,851,973 		JBrowse link
G KMT2C lysine methyltransferase 2C treatment ISO RGD PMID:33914205 RGD:151356764 NCBI chr18:4,993,213...5,279,668
Ensembl chr18:4,993,227...5,278,723 		JBrowse link
G LCN2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7554268 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644 		JBrowse link
G LHX2 LIM homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 1:264,900,931...264,920,888
Ensembl chr 1:264,900,591...264,920,890 		JBrowse link
G LOC110258578 interleukin-1 beta-like ISO protein:decreased expression:serum
mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12566094 PMID:17379860 PMID:22414257 PMID:22450443 PMID:22660635 RGD:155663483 RGD:6482656
G LRRK2 leucine rich repeat kinase 2 ISO RGD PMID:17082220 RGD:5508419 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G LY96 lymphocyte antigen 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 4:61,919,806...61,950,712
Ensembl chr 4:61,926,064...61,950,697 		JBrowse link
G MAB21L2 mab-21 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 8:78,385,176...78,388,008
Ensembl chr 8:78,385,764...78,386,843 		JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:79,789,796...79,795,895
Ensembl chr 1:79,789,815...79,795,760 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr 1:103,683,077...103,768,372
Ensembl chr 1:103,735,192...103,752,402 		JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility
no_association		 ISO DNA:snps:introns:IVS5-140A>G (rs3138355), IVS6-218C>T (rs2005618) (human)
DNA:snps:cds, intron:p.E346K, IVS6-218C>T (rs140693, rs2005618) (human)		 RGD PMID:20676650 PMID:22505706 RGD:9588977 RGD:9588978 NCBI chr13:68,816,677...68,828,559
Ensembl chr13:68,816,679...68,828,580 		JBrowse link
G MDK midkine ISO RGD PMID:15146411 RGD:1581200 NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,788...16,133,510 		JBrowse link
G MGARP mitochondria localized glutamic acid rich protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 8:87,708,887...87,723,126
Ensembl chr 8:87,697,544...87,723,125 		JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
G MIR23B microRNA mir-23b ISO mRNA, protein:decreased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr10:27,080,197...27,080,276
Ensembl chr10:27,080,197...27,080,276 		JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 6:64,436,778...64,470,888
Ensembl chr 6:64,436,642...64,472,759 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076 		JBrowse link
G MMP12 matrix metallopeptidase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:33,473,625...33,483,630
Ensembl chr 9:33,473,093...33,483,679 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO OMIM:180300 MouseDO NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MMP3 matrix metallopeptidase 3 disease_progression ISO protein:increased expression:serum (human) RGD PMID:7639798 PMID:11796404 PMID:22314025 RGD:7207128 RGD:7241254 RGD:8693673 NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,446,836...33,454,000 		JBrowse link
G MMP8 matrix metallopeptidase 8 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr 9:33,384,034...33,397,637
Ensembl chr 9:33,384,033...33,396,947 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:16406300 RGD:1582623 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 PMID:26001728 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 ISO DNA:missense mutations:cds:multiple (human) RGD PMID:15987486 RGD:5490238 NCBI chr MT:3,922...4,876
Ensembl chr MT:3,922...4,876 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :677C>T(human)		 CTD
RGD		 PMID:22104130 PMID:23685257 RGD:7387222 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 induced ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:M153T (rat)		 CTD
RGD		 PMID:12833524 PMID:21275845 PMID:28135245 RGD:41404729 NCBI chr 3:11,820,367...11,834,394
Ensembl chr 3:11,820,266...11,839,354 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism, SNP:cds (rs789181) (human)		 CTD
RGD		 PMID:12833524 PMID:17897462 RGD:41404710 NCBI chr 9:124,776,516...124,813,358
Ensembl chr 9:124,776,534...124,812,923 		JBrowse link
G NCF4 neutrophil cytosolic factor 4 ISO DNA:polymorphism, SNP:cds (rs729749) (human) RGD PMID:17897462 RGD:41404710 NCBI chr 5:10,876,147...10,994,002
Ensembl chr 5:10,874,953...10,994,014 		JBrowse link
G NDUFA4L2 NDUFA4 mitochondrial complex associated like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 5:22,540,482...22,548,418
Ensembl chr 5:22,535,740...22,548,882 		JBrowse link
G NFKBIE NFKB inhibitor epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 7:39,255,078...39,266,085
Ensembl chr 7:39,255,075...39,263,339 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis OMIM
ClinVar		 PMID:12509789 NCBI chr 7:23,673,002...23,685,089
Ensembl chr 7:23,673,297...23,685,088 		JBrowse link
G NOTCH4 notch receptor 4 ISO mRNA : increased expression: : cd4+ cells RGD PMID:20132067 RGD:6480790 NCBI chr 7:24,231,293...24,256,281
Ensembl chr 7:24,231,293...24,256,281 		JBrowse link
G NPSR1 neuropeptide S receptor 1 ISO RGD PMID:20179762 RGD:4891930 NCBI chr18:38,942,499...39,212,791
Ensembl chr18:38,942,487...39,085,754 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO mRNA:increased expression:paw RGD PMID:18448865 RGD:4892311 NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,939...144,956,451 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:241,569,867...241,611,735
Ensembl chr 1:241,570,010...241,611,727 		JBrowse link
G OPRM1 opioid receptor mu 1 susceptibility ISO DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human) RGD PMID:31309790 RGD:401827955 NCBI chr 1:12,634,125...12,702,295
Ensembl chr 1:12,528,672...12,702,443 		JBrowse link
G PADI2 peptidyl arginine deiminase 2 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr 6:75,696,476...75,755,977
Ensembl chr 6:75,696,481...75,755,890 		JBrowse link
G PADI4 peptidyl arginine deiminase 4 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr 6:75,935,909...75,966,275
Ensembl chr 6:75,935,889...75,966,293 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO RGD PMID:1708827 RGD:6482653 Ensembl chr 5:8,986,462...9,007,435 JBrowse link
G PGF placental growth factor ISO RGD PMID:19180491 RGD:6483591 NCBI chr 7:98,149,510...98,162,784
Ensembl chr 7:98,148,994...98,162,741 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:increased expression:cartilage tissue (human) RGD PMID:31472145 RGD:152177908 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G PLA2G7 phospholipase A2 group VII ISO RGD PMID:17326817 RGD:6482776 NCBI chr 7:41,488,152...41,531,383
Ensembl chr 7:41,486,598...41,531,345 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO RGD PMID:22011479 RGD:6484117 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418 		JBrowse link
G PLB1 phospholipase B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24520335 NCBI chr 3:110,605,923...110,741,236
Ensembl chr 3:110,605,923...110,741,130 		JBrowse link
G PLD4 phospholipase D family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963
G PLEK pleckstrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 3:73,877,741...73,910,163
Ensembl chr 3:73,877,743...73,906,667 		JBrowse link
G PON1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16055108 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
G POU3F1 POU class 3 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 6:94,025,133...94,028,053
Ensembl chr 6:94,026,675...94,028,030 		JBrowse link
G PRDM1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898481 PMID:20453842 PMID:23143596 PMID:36181686 NCBI chr 1:72,309,096...72,335,474
Ensembl chr 1:72,311,880...72,335,466 		JBrowse link
G PRKCQ protein kinase C theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chr10:64,442,588...64,596,528
Ensembl chr10:64,458,180...64,600,339 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15167967 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:11978490 PMID:19192274 PMID:21905970 RGD:5508313 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PTK2 protein tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,253...96,847,125 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 susceptibility
no_association		 ISO ClinVar Annotator: match by term: Rheumatoid arthritis
DNA:SNP::1858C>T (human)		 OMIM
ClinVar
RGD		 PMID:21467606 PMID:25741868 RGD:7829746 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G PXK PX domain containing serine/threonine kinase like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chr13:40,079,238...40,160,387
Ensembl chr13:40,074,466...40,160,380 		JBrowse link
G RAB8A RAB8A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 2:61,430,680...61,450,351
Ensembl chr 2:61,429,523...61,450,413 		JBrowse link
G RAP2A RAP2A, member of RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:66,679,162...66,718,565
Ensembl chr11:66,679,253...66,720,045 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:132,702,495...132,786,536
Ensembl chr 1:132,702,541...132,786,532 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
G RCAN1 regulator of calcineurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr13:198,106,256...198,205,727
Ensembl chr13:198,102,098...198,205,629 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19503088 PMID:20453842 PMID:23143596 NCBI chr 3:80,861,862...80,912,233
Ensembl chr 3:80,872,255...80,911,939 		JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:105,042,479...105,070,428
Ensembl chr 2:105,042,532...105,070,409 		JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr13:198,371,835...198,635,648
Ensembl chr13:198,371,837...198,638,189 		JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687 		JBrowse link
G SEMA3C semaphorin 3C ISO protein:increased expression:knee, synovium (human) RGD PMID:15077297 RGD:1580084 NCBI chr 9:99,114,649...99,432,683
Ensembl chr 9:99,251,715...99,433,224 		JBrowse link
G SLA-DQA1 MHC class II histocompatibility antigen SLA-DQA ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 7:24,953,472...24,959,313 JBrowse link
G SLC11A1 solute carrier family 11 member 1 severity ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphisms, deletion: :823C>T, p.D543N (human)
DNA:polymorphism:promoter (human)		 CTD
RGD		 PMID:10719815 PMID:12135431 PMID:16597321 RGD:5684967 RGD:5684971 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SLC22A4 solute carrier family 22 member 4 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis | ClinVar Annotator: match by term: SLC22A4-related condition OMIM
ClinVar		 PMID:14608356 PMID:19881261 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 2:134,594,843...134,641,403
Ensembl chr 2:134,595,584...134,639,777 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr15:77,895,935...78,021,930
Ensembl chr15:77,895,938...78,098,383 		JBrowse link
G SMS spermine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr  X:18,118,332...18,169,396
Ensembl chr  X:18,118,256...18,169,390 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 PMID:15292528 PMID:24313545 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:15761492 RGD:1581382 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 3:76,527,646...76,649,652
Ensembl chr 3:76,523,589...76,649,651 		JBrowse link
G ST6GALNAC5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:17568789 NCBI chr 6:136,207,838...136,391,083
Ensembl chr 6:136,204,374...136,390,995 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO associated with T-cell large granular lymphocyte leukemia RGD PMID:22591296 RGD:6892936 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr15:95,656,206...95,764,099
Ensembl chr15:95,656,077...95,763,472 		JBrowse link
G STS steroid sulfatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr  X:3,926,027...4,076,900
NCBI chr  Y:2,747,102...2,828,322 		JBrowse link
G SUPT20H SPT20 homolog, SAGA complex component ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr11:12,825,758...12,864,935
Ensembl chr11:12,825,762...12,864,929 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO mRNA, protein:increased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr 1:16,533,364...16,611,879
Ensembl chr 1:16,533,285...16,611,884 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 ISO mRNA, protein:increased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr  X:26,632,547...26,729,039
Ensembl chr  X:26,632,551...26,729,051 		JBrowse link
G TAGAP T cell activation RhoGTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 1:8,209,298...8,217,993
Ensembl chr 1:8,209,314...8,219,630 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:9645419 RGD:6482275 NCBI chr 7:25,045,085...25,056,915
Ensembl chr 7:25,043,840...25,056,922 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 PMID:17379860 NCBI chr 9:73,684,236...73,694,663
Ensembl chr 9:73,673,535...73,689,095 		JBrowse link
G THBD thrombomodulin ISO RGD PMID:15700117 RGD:5685020 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,217,303...30,224,099 		JBrowse link
G TLE3 TLE family member 3, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:167,808,508...167,855,913
Ensembl chr 1:167,808,510...167,855,911 		JBrowse link
G TLR1 toll like receptor 1 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:32594150 NCBI chr 8:30,147,600...30,155,454
Ensembl chr 8:30,147,624...30,155,466 		JBrowse link
G TLR2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TMPO thymopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 5:85,317,648...85,346,528
Ensembl chr 5:85,315,290...85,346,538 		JBrowse link
G TNF tumor necrosis factor treatment
no_association		 ISO mRNA:increased expression:synovial (human)
OMIM:180300
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:SNP:promoter:-238G>A, -308G>A (human)
DNA:SNP:promoter:-857C>T (human)		 RGD
MouseDO
CTD		 PMID:2001072 PMID:8391952 PMID:12563673 PMID:12566094 PMID:22450443 More... RGD:10450537 RGD:12904065 RGD:155663483 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFAIP2 TNF alpha induced protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274
G TNFAIP3 TNF alpha induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:21841782 PMID:23143596 PMID:30224649 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b ISO CTD Direct Evidence: therapeutic CTD PMID:23333834 NCBI chr 4:19,850,212...19,879,132
Ensembl chr 4:19,850,350...19,879,125 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO DNA:SNP:promoter:36G>A (human) RGD PMID:25311255 RGD:12904065 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,051...64,331,909 		JBrowse link
G TNFSF14 TNF superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 2:72,478,178...72,483,885
Ensembl chr 2:72,473,477...72,483,989 		JBrowse link
G TRAF1 TNF receptor associated factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:23143596 NCBI chr 1:260,948,191...260,973,978
Ensembl chr 1:260,949,111...260,973,709 		JBrowse link
G TRAF6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,804...24,626,072 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment ISO RGD PMID:27049384 RGD:127229930 NCBI chr 7:36,510,253...36,531,796
Ensembl chr 7:36,510,253...36,531,796 		JBrowse link
G TXNDC5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23326410 NCBI chr 7:5,210,192...5,236,857
Ensembl chr 7:5,210,064...5,236,812 		JBrowse link
G TXNIP thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 4:99,348,589...99,351,760
Ensembl chr 4:99,348,490...99,352,755 		JBrowse link
G TYK2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chr 2:69,157,774...69,183,555
Ensembl chr 2:69,157,811...69,183,456 		JBrowse link
G TYMS thymidylate synthetase treatment ISO DNA:polymorphism: : RGD PMID:22763757 RGD:11075093 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,642,381...105,660,578 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP treatment ISO RGD PMID:27049384 RGD:127229930 NCBI chr 6:45,309,199...45,312,562
Ensembl chr 6:45,309,201...45,312,539 		JBrowse link
G VDR vitamin D receptor no_association ISO DNA:SNP:exon:rs2228570 (human)
DNA:SNP: :rs1544410 (human)		 RGD PMID:21820934 RGD:8158077 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,266,475 		JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:		 CTD
RGD		 PMID:16368150 PMID:24387171 RGD:8548659 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
G VIM vimentin ISO RGD PMID:21792832 RGD:6480508 NCBI chr10:43,516,441...43,526,172
Ensembl chr10:43,517,307...43,526,170 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 ISO OMIM:180300 MouseDO NCBI chr 3:56,515,446...56,541,806
Ensembl chr 3:56,515,449...56,541,740 		JBrowse link
G ZFP36 ZFP36 ring finger protein ISO OMIM:180300 MouseDO NCBI chr 6:48,063,732...48,066,235
Ensembl chr 6:48,063,677...48,066,250 		JBrowse link
adult-onset Still's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HGF hepatocyte growth factor ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:73,471,837...73,530,778
Ensembl chr13:73,471,889...73,530,011 		JBrowse link
G ACRBP acrosin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:64,036,810...64,047,846
Ensembl chr 5:64,037,095...64,047,847 		JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:34,521,503...34,586,384
Ensembl chr 6:34,519,180...34,585,779 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G ANKRD9 ankyrin repeat domain 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504
G AOPEP aminopeptidase O (putative) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:27,078,115...27,472,347
Ensembl chr10:27,078,113...27,472,310 		JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:113,798,380...113,848,452
Ensembl chr 1:113,794,040...113,848,683 		JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:70,417,935...70,428,106
Ensembl chr 8:70,417,923...70,428,102 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:10,103,860...10,451,928
Ensembl chr 4:10,179,758...10,451,929 		JBrowse link
G AVL9 AVL9 cell migration associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:40,663,728...40,739,115
Ensembl chr18:40,663,730...40,739,080 		JBrowse link
G B4GALT5 beta-1,4-galactosyltransferase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:51,257,273...51,334,566
Ensembl chr17:51,259,813...51,334,020 		JBrowse link
G BEND2 BEN domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:14,635,795...14,703,934 JBrowse link
G BLTP3B bridge-like lipid transfer protein family member 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:83,935,628...84,041,753
Ensembl chr 5:83,935,703...84,042,202 		JBrowse link
G BTG1 BTG anti-proliferation factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:90,815,194...90,817,936
Ensembl chr 5:90,815,202...90,817,142 		JBrowse link
G BTG3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:182,209,850...182,228,626
Ensembl chr13:182,208,958...182,227,971 		JBrowse link
G C15H2orf88 chromosome 15 C2orf88 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:94,628,283...94,794,114
Ensembl chr15:94,478,021...94,791,775 		JBrowse link
G C8B complement C8 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chr 6:155,411,982...155,453,034
Ensembl chr 6:155,387,145...155,453,438 		JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:38,389,366...38,415,903
Ensembl chr10:38,389,331...38,415,901 		JBrowse link
G CALD1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726 		JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504
G CCDC122 coiled-coil domain containing 122 ISO ClinVar Annotator: match by term: JUVENILE ARTHRITIS ClinVar PMID:25741868 NCBI chr11:23,159,655...23,199,074
Ensembl chr11:23,159,470...23,198,885 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
DNA:polymorphisms: :multiple (human)		 RGD PMID:16775617 PMID:17565662 RGD:1626283 RGD:1626284 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CD14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G CD83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:10,346,122...10,385,968
Ensembl chr 7:10,359,211...10,385,961 		JBrowse link
G CD8B CD8 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:57,968,358...57,986,450
Ensembl chr 3:57,968,383...57,986,441 		JBrowse link
G CIITA class II major histocompatibility complex transactivator no_association
susceptibility		 ISO DNA:polymorphism:promoter:rs3087456, no association in a German cohort
DNA:polymorphism:exon:1614G>C (human)		 RGD PMID:16426246 PMID:17661914 RGD:5491187 RGD:5491189 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780 		JBrowse link
G CLU clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G CMTM2 CKLF like MARVEL transmembrane domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:27,281,809...27,295,429
Ensembl chr 6:27,282,070...27,295,522 		JBrowse link
G CREM cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:57,829,523...57,895,610
Ensembl chr10:57,829,518...57,895,610 		JBrowse link
G CRP C-reactive protein, pentraxin-related ISO protein:increased expression:serum RGD PMID:22885951 RGD:6906884 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103 		JBrowse link
G CTTN cortactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 PMID:26387944 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232 		JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086 		JBrowse link
G DUSP2 dual specificity phosphatase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:47,052,443...47,054,816
Ensembl chr 3:47,052,458...47,054,810 		JBrowse link
G DUSP4 dual specificity phosphatase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:55,491,084...55,508,460
Ensembl chr15:55,491,087...55,508,455 		JBrowse link
G DYSF dysferlin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:71,020,143...71,237,658
Ensembl chr 3:71,020,144...71,246,967 		JBrowse link
G EGF epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046 		JBrowse link
G EGR1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G ELF2 E74 like ETS transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:87,774,594...87,878,847
Ensembl chr 8:87,854,699...87,878,662 		JBrowse link
G ETNK1 ethanolamine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:50,914,808...50,970,748
Ensembl chr 5:50,914,814...50,970,697 		JBrowse link
G ETV6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:60,523,530...60,776,792
Ensembl chr 5:60,523,433...60,776,750 		JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:11,606,469...11,663,086
Ensembl chr12:11,607,034...11,657,737 		JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:68,359,243...68,389,968
Ensembl chr16:68,359,307...68,389,965 		JBrowse link
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:99,233,632...99,242,531
Ensembl chr 4:99,233,611...99,242,586 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,523...7,608,469 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:51,836,780...51,844,531
Ensembl chr 6:51,837,719...51,844,529 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:110,820,403...110,842,903
Ensembl chr 3:110,823,666...110,843,068 		JBrowse link
G FOXP1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:144,940,702...144,944,089
Ensembl chr 6:144,940,697...144,944,089 		JBrowse link
G GMPR guanosine monophosphate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:12,254,393...12,298,802
Ensembl chr 7:12,254,388...12,299,531 		JBrowse link
G GNG11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:73,721,327...73,726,229
Ensembl chr 9:73,721,322...73,726,222 		JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:51,261,097...51,261,903
Ensembl chr14:51,260,963...51,262,114 		JBrowse link
G H2AC4 H2A clustered histone 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:20,729,940...20,730,466
Ensembl chr 7:20,729,997...20,730,389 		JBrowse link
G HBEGF heparin binding EGF like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:142,102,455...142,115,192
Ensembl chr 2:142,102,458...142,115,174 		JBrowse link
G HERPUD2 HERPUD family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:38,284,520...38,326,323
Ensembl chr18:38,284,520...38,326,311 		JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:88,970,592...88,973,109
Ensembl chr 4:88,970,599...88,973,918 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G IL1A interleukin 1 alpha ISO DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504
G IL2 interleukin 2 ISO protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum: RGD PMID:9489833 RGD:7829742 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G ITGA2B integrin subunit alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:18,860,739...18,877,381
Ensembl chr12:18,860,739...18,877,381 		JBrowse link
G ITGB5 integrin subunit beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:135,468,111...135,587,483
Ensembl chr13:135,467,798...135,587,473 		JBrowse link
G JMJD1C jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:66,640,845...66,966,911
Ensembl chr14:66,640,849...66,920,324 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G KAT6B lysine acetyltransferase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:77,390,790...77,597,674
Ensembl chr14:77,404,136...77,597,673 		JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:201,894,036...201,941,449
Ensembl chr13:201,894,420...201,939,789 		JBrowse link
G KLF4 KLF transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:248,604,817...248,609,574
Ensembl chr 1:248,604,820...248,609,035 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358 		JBrowse link
G LACC1 laccase domain containing 1 ISO ClinVar Annotator: match by term: JUVENILE ARTHRITIS OMIM
ClinVar		 PMID:25147203 PMID:25220867 PMID:25741868 PMID:27881174 PMID:29717096 More... NCBI chr11:23,143,708...23,159,790
Ensembl chr11:23,141,425...23,159,547 		JBrowse link
G LOC102160336 ubiquitin-conjugating enzyme E2 E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:10,605,837...10,683,819
Ensembl chr13:10,605,503...10,683,816 		JBrowse link
G LPP LIM domain containing preferred translocation partner in lipoma ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:125,782,373...126,478,927
Ensembl chr13:125,782,471...126,463,303 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041 		JBrowse link
G MAFF MAF bZIP transcription factor F ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:9,683,651...9,696,128
Ensembl chr 5:9,683,660...9,696,023 		JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:27,993,319...28,372,982
Ensembl chr 9:27,997,887...28,371,397 		JBrowse link
G MAP2 microtubule associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:112,156,578...112,462,932
Ensembl chr15:112,236,119...112,462,929 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MBL2 mannose binding lectin 2 ISO RGD PMID:18334024 RGD:12910845 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083 		JBrowse link
G MEX3C mex-3 RNA binding family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:100,678,452...100,699,277
Ensembl chr 1:100,676,660...100,699,403 		JBrowse link
G MS4A4A membrane spanning 4-domains A4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:11,226,146...11,368,033 JBrowse link
G MSN moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:51,844,197...51,967,674
Ensembl chr  X:51,844,156...51,970,107 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:14,933,290...15,103,256
Ensembl chr 4:14,933,331...15,103,253 		JBrowse link
G MYZAP myocardial zonula adherens protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:114,287,622...114,386,418
Ensembl chr 1:114,287,627...114,386,427 		JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:53,553,897...53,640,470
Ensembl chr12:53,557,175...53,640,457 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:63,487,051...63,506,249
Ensembl chr15:63,487,731...63,495,299 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:241,569,867...241,611,735
Ensembl chr 1:241,570,010...241,611,727 		JBrowse link
G NRG1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,630,679...52,839,505 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:61,799,356...61,809,691
Ensembl chr 5:61,799,286...61,810,624 		JBrowse link
G OSM oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:47,242,767...47,246,836
Ensembl chr14:47,242,774...47,246,838 		JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:5,853,377...5,985,174
Ensembl chr 5:5,853,377...5,985,169 		JBrowse link
G PCYT1B phosphate cytidylyltransferase 1B, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:20,605,769...20,743,081
Ensembl chr  X:20,605,945...20,743,134 		JBrowse link
G PER1 period circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:53,361,863...53,376,723
Ensembl chr12:53,361,889...53,374,248 		JBrowse link
G PGM5 phosphoglucomutase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:221,634,516...221,837,764
Ensembl chr 1:221,634,524...221,836,459 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418 		JBrowse link
G PLK2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:37,299,116...37,305,114
Ensembl chr16:37,299,119...37,305,114 		JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:86,402,673...86,513,167
Ensembl chr13:86,401,244...86,513,105 		JBrowse link
G PROS1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:165,915,298...165,999,118
Ensembl chr13:165,911,366...165,999,811 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G R3HDM2 R3H domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:22,558,645...22,714,250
Ensembl chr 5:22,549,010...22,719,054 		JBrowse link
G RASGEF1B RasGEF domain family member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:135,896,022...136,595,051
Ensembl chr 8:136,568,711...136,595,049 		JBrowse link
G RBM47 RNA binding motif protein 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:31,508,133...31,690,757
Ensembl chr 8:31,508,148...31,690,409 		JBrowse link
G RERE arginine-glutamic acid dipeptide repeats ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:68,954,766...69,258,855 JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:64,326,461...64,465,331
Ensembl chr14:64,326,461...64,465,281 		JBrowse link
G RNF103 ring finger protein 103 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:58,161,087...58,183,750
Ensembl chr 3:58,161,261...58,186,858 		JBrowse link
G SELP selectin P severity ISO protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G SH2D2A SH2 domain containing 2A ISO DNA:polymorphism:promoter RGD PMID:15129233 RGD:2298870 NCBI chr 4:93,282,383...93,293,214
Ensembl chr 4:93,282,413...93,293,205 		JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:86,416,281...86,481,805
Ensembl chr 1:86,358,483...86,481,776 		JBrowse link
G SIK1 salt inducible kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:206,454,695...206,465,802
Ensembl chr13:206,454,718...206,465,807 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:94,789,794...95,168,728
Ensembl chr 7:95,022,924...95,167,107 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10857800 PMID:16597321 RGD:5684977 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SLC22A16 solute carrier family 22 member 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:76,423,386...76,468,267
Ensembl chr 1:76,423,355...76,467,575 		JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility ISO DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chr 2:150,996,868...151,027,483
Ensembl chr 2:150,996,686...151,022,148 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:62,963,635...63,041,955 JBrowse link
G SMAD3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G STAB1 stabilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:34,630,448...34,659,371
Ensembl chr13:34,636,083...34,659,219 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G STIM1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575 		JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417 		JBrowse link
G TFDP1 transcription factor Dp-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:78,755,472...78,778,312
Ensembl chr11:78,755,533...78,778,309 		JBrowse link
G TFPI tissue factor pathway inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:92,345,083...92,409,962
Ensembl chr15:92,345,075...92,409,905 		JBrowse link
G THBD thrombomodulin ISO protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,217,303...30,224,099 		JBrowse link
G THBS1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:862,013...881,352
Ensembl chr15:862,015...881,461 		JBrowse link
G TNFAIP8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:123,152,349...123,285,154
Ensembl chr 2:123,152,371...123,287,941 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:109,642,848...110,052,345
Ensembl chr13:109,643,895...110,052,236 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:36,455,628...36,460,711
Ensembl chr 7:36,455,634...36,460,715 		JBrowse link
G TTLL5 tubulin tyrosine ligase like 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:98,822,338...99,090,076
Ensembl chr 7:98,823,871...99,130,915 		JBrowse link
G UBE3C ubiquitin protein ligase E3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:1,542,454...1,654,274
Ensembl chr18:1,542,163...1,653,982 		JBrowse link
G WASF3 WASP family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:4,261,121...4,366,258
Ensembl chr11:4,261,177...4,366,253 		JBrowse link
G WWOX WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053 		JBrowse link
G ZFAND3 zinc finger AN1-type containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:33,378,229...33,718,034
Ensembl chr 7:33,378,286...33,718,030 		JBrowse link
G ZFC3H1 zinc finger C3H1-type containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:35,617,257...35,671,191
Ensembl chr 5:35,617,266...35,671,149 		JBrowse link
Sjogren's syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIRE autoimmune regulator ISO OMIM:270150 MouseDO NCBI chr13:207,148,401...207,158,355
Ensembl chr13:207,148,401...207,158,346 		JBrowse link
G APOE apolipoprotein E onset ISO DNA:polymorphism:exon: RGD PMID:15328426 RGD:7495765 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G BDNF brain derived neurotrophic factor severity ISO protein:increased expression:serum: RGD PMID:18830907 RGD:8657019 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 ISO mRNA, protein:increased expression: labial gland, CD19+ B cell, CD4-CD8-CD19-monocyte: RGD PMID:30249485 RGD:14398821 NCBI chr 2:60,305,306...60,308,295
Ensembl chr 2:60,305,283...60,309,697 		JBrowse link
G C3 complement C3 ISO RGD PMID:17675493 RGD:7401265 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228 		JBrowse link
G CA1 carbonic anhydrase 1 ISO RGD PMID:12806141 RGD:408425977 NCBI chr 4:51,343,548...51,353,127
Ensembl chr 4:51,302,406...51,353,126 		JBrowse link
G CA2 carbonic anhydrase 2 ISO RGD PMID:12806141 PMID:15831920 RGD:408425973 RGD:408425977 NCBI chr 4:51,194,686...51,211,436
Ensembl chr 4:51,193,756...51,211,259 		JBrowse link
G CAST calpastatin ISO associated with Lupus Erythematosus, Systemic RGD PMID:15540513 RGD:5683622 NCBI chr 2:103,255,738...103,378,623
Ensembl chr 2:103,255,750...103,378,623 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation: :p.S185_T195del (rs333) (human) RGD PMID:12412204 PMID:23773920 RGD:8551796 RGD:8551818 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO OMIM:270150 MouseDO NCBI chr12:21,857,286...21,869,211
Ensembl chr12:21,857,286...21,872,475 		JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:salivary ductal epithelium (human) RGD PMID:12472667 RGD:11520791 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709 		JBrowse link
G CRP C-reactive protein, pentraxin-related ISO associated with Arthritis, Rheumatoid;protein:increased expression:serum: RGD PMID:2353152 PMID:16013223 RGD:9491774 RGD:9491835 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility ISO DNA:SNPs,haplotype: :+49A/G (rs231775),(rs3087243)(human)
mRNA:increased expression:salivary gland:		 RGD PMID:12528117 PMID:16869018 RGD:7421506 RGD:7421519 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103 		JBrowse link
G CYP19A2 cytochrome P450 19A2 ISO OMIM:270150 MouseDO NCBI chr 1:120,652,172...120,695,899
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO associated with Arthritis, Rheumatoid;DNA:polymorphism: :4889A>G (human) RGD PMID:12590982 RGD:5147747 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G DGKQ diacylglycerol kinase theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 8:313,325...325,089
Ensembl chr 8:313,329...325,095 		JBrowse link
G E2F1 E2F transcription factor 1 ISO OMIM:270150 MouseDO NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883 		JBrowse link
G FAS Fas cell surface death receptor ISO protein:decreased expression:lacrimal gland, lymphocyte (mouse)
OMIM:270150
protein:increased expression:serum (human)		 RGD
MouseDO		 PMID:9870874 PMID:9890678 PMID:11157873 RGD:8662410 RGD:8662436 RGD:8662451 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G GDNF glial cell derived neurotrophic factor ISO RGD PMID:9853108 RGD:6218983 NCBI chr16:22,936,602...22,965,929
Ensembl chr16:22,936,604...22,966,536 		JBrowse link
G GTF2I general transcription factor IIi ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097066 NCBI chr 3:11,656,928...11,811,426
Ensembl chr 3:11,671,575...11,811,423 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO RGD PMID:24941846 RGD:10450595
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 ISO RGD PMID:19264855 RGD:10054311 NCBI chr 2:78,961,456...78,971,799
Ensembl chr 2:78,963,309...78,969,949 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO protein:increased expression:salivary gland
protein:increased expression:plasma		 RGD PMID:11359451 PMID:15037117 PMID:21589878 RGD:8158122 RGD:8547696 RGD:8547705 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G ID3 inhibitor of DNA binding 3 ISO OMIM:270150 MouseDO NCBI chr 6:81,422,541...81,424,169
Ensembl chr 6:81,422,546...81,424,075 		JBrowse link
G IFNG interferon gamma ISO RGD PMID:15584966 PMID:28421993 RGD:14975117 RGD:8142390 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL10 interleukin 10 ISO RGD PMID:12233881 RGD:1580479 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL12A interleukin 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr13:99,733,394...99,741,078
Ensembl chr13:99,733,394...99,741,078 		JBrowse link
G IL13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093 		JBrowse link
G IL17A interleukin 17A ISO RGD PMID:21182786 RGD:8696035 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL18 interleukin 18 ISO protein:increased expression:saliva RGD PMID:23906036 RGD:8655918 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:increased expression:conjunctiva (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)		 RGD PMID:9646842 PMID:11527941 RGD:8549786 RGD:8549807
G IL2 interleukin 2 ISO OMIM:270150 MouseDO NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL23R interleukin 23 receptor ISO protein:increased expression:minor salivary gland: RGD PMID:22262980 RGD:8549566 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO OMIM:270150 MouseDO NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,563...65,001,142 		JBrowse link
G IL4 interleukin 4 ISO OMIM:270150 MouseDO NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL6 interleukin 6 severity ISO protein:increased expression:plasma:
DNA:polymorphims:promoter:-174G>C(human)		 RGD PMID:11426023 RGD:7829718 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 1:87,289,964...87,329,926
Ensembl chr 1:87,290,826...87,329,716 		JBrowse link
G ITSN2 intersectin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 3:114,363,319...114,508,447
Ensembl chr 3:114,363,529...114,508,444 		JBrowse link
G LTA lymphotoxin alpha no_association
susceptibility		 ISO DNA:SNPs: :multiple (human)
DNA:SNP, haplotype:intron: (rs909253) (human)
protein:increased expression:saliva, serum		 RGD PMID:20952683 PMID:22294627 RGD:8548776 RGD:8548787 NCBI chr 7:23,696,387...23,698,280
Ensembl chr 7:23,696,040...23,698,299 		JBrowse link
G MAP3K14 mitogen-activated protein kinase kinase kinase 14 ISO OMIM:270150 MouseDO NCBI chr12:18,142,899...18,182,931
Ensembl chr12:18,142,952...18,182,928 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO RGD PMID:19332626 RGD:8693671 NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,446,836...33,454,000 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased activity:saliva RGD PMID:9923658 PMID:15316122 RGD:8547814 RGD:8547858 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MUC19 mucin 19, oligomeric ISO mRNA:decreased expression:conjunctival epithelial cell
OMIM:270150		 RGD
MouseDO		 PMID:18184611 RGD:7364736 NCBI chr 5:71,964,131...72,069,073 JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO mRNA:decreased expression:conjunctival epithelial cell RGD PMID:18184611 RGD:7364736 NCBI chr 2:757,897...790,321 JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28135245 NCBI chr 3:11,820,367...11,834,394
Ensembl chr 3:11,820,266...11,839,354 		JBrowse link
G NEFL neurofilament light chain ISO protein:increased expression:CSF (human) RGD PMID:32423153 RGD:127284890 NCBI chr14:8,991,321...8,996,900
Ensembl chr14:8,991,331...8,997,112 		JBrowse link
G NFKBIA NFKB inhibitor alpha ISO OMIM:270150 RGD
MouseDO		 PMID:20696914 RGD:126908016 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G PHIP pleckstrin homology domain interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 1:87,116,884...87,247,500
Ensembl chr 1:87,117,092...87,243,675 		JBrowse link
G PON1 paraoxonase 1 ISO protein:decreased activity:serum (human) RGD PMID:20497955 RGD:8547550 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
G PRDM1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 1:72,309,096...72,335,474
Ensembl chr 1:72,311,880...72,335,466 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 no_association ISO DNA:snp:cds:c.1858C>T (human) RGD PMID:15933742 PMID:16163373 RGD:11534998 RGD:11534999 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G RORC RAR related orphan receptor C ISO OMIM:270150 MouseDO NCBI chr 4:97,374,672...97,399,017
Ensembl chr 4:97,375,136...97,400,209 		JBrowse link
G SATB1 SATB homeobox 1 ISO OMIM:270150 MouseDO NCBI chr13:5,315,985...5,410,686
Ensembl chr13:5,314,148...5,417,610 		JBrowse link
G SELP selectin P ISO protein:increased expression:plasma RGD PMID:19832990 RGD:6478702 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO OMIM:270150 MouseDO NCBI chr 9:56,888,246...56,929,771
Ensembl chr 9:56,888,246...56,929,767 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 susceptibility
no_association		 ISO DNA:SNP:intron: (rs7582694) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs7574865) (human)		 RGD
CTD		 PMID:18273036 PMID:20360187 PMID:20535138 PMID:24097066 PMID:24097067 RGD:8661690 RGD:8661708 RGD:8661709 NCBI chr15:95,656,206...95,764,099
Ensembl chr15:95,656,077...95,763,472 		JBrowse link
G TGFB1 transforming growth factor beta 1 severity ISO OMIM:270150 RGD
MouseDO		 PMID:7554451 PMID:9358754 RGD:7394829 RGD:7394845 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G THBS1 thrombospondin 1 ISO OMIM:270150 MouseDO NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
G TNF tumor necrosis factor treatment ISO DNA:polymorphism: :-1031T>C(human) RGD PMID:22703762 PMID:24941846 RGD:10450595 RGD:7394766 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097066 PMID:24097067 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
G TNFSF13B TNF superfamily member 13b ISO OMIM:270150 MouseDO NCBI chr11:75,599,296...75,633,044
Ensembl chr11:75,599,598...75,633,041 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr16:71,926,038...71,979,969
Ensembl chr16:71,926,133...71,979,966 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 ISO OMIM:270150 MouseDO NCBI chr 1:77,483,997...77,541,557
Ensembl chr 1:77,487,577...77,541,198 		JBrowse link
G VIM vimentin ISO RGD PMID:6352937 RGD:6480477 NCBI chr10:43,516,441...43,526,172
Ensembl chr10:43,517,307...43,526,170 		JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:22059987 RGD:5685375 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269 		JBrowse link
Systemic Juvenile Rheumatoid Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:26914138 RGD:11529541 NCBI chr17:9,245,283...9,260,140
Ensembl chr17:9,245,196...9,260,473 		JBrowse link
G IL6 interleukin 6 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IL6R interleukin 6 receptor treatment ISO RGD PMID:18358927 RGD:10402823 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,433...95,381,282 		JBrowse link
G MIF macrophage migration inhibitory factor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15436
    disease of anatomical entity 15105
      musculoskeletal system disease 7847
        connective tissue disease 5380
          rheumatic disease 686
            rheumatoid arthritis 429
              Caplan's syndrome 0
              Felty's syndrome 0
              Rheumatoid Nodule 0
              Rheumatoid Vasculitis 0
              Sjogren's syndrome + 65
              Sjögren-Mikulicz Syndrome 0
              adult-onset Still's disease 2
              juvenile rheumatoid arthritis + 142
              palindromic rheumatism 0
Path 2
Term Annotations click to browse term
  disease 15436
    disease of anatomical entity 15105
      Skin and Connective Tissue Diseases 7054
        connective tissue disease 5380
          bone disease 3877
            bone inflammation disease 1341
              arthropathy 1323
                arthritis 899
                  rheumatoid arthritis 429
                    Caplan's syndrome 0
                    Felty's syndrome 0
                    Rheumatoid Nodule 0
                    Rheumatoid Vasculitis 0
                    Sjogren's syndrome + 65
                    Sjögren-Mikulicz Syndrome 0
                    adult-onset Still's disease 2
                    juvenile rheumatoid arthritis + 142
                    palindromic rheumatism 0
paths to the root