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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:hepatocellular carcinoma
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Accession:DOID:684 term browser browse the term
Definition:A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Synonyms:exact_synonym: Adult Liver Cancer;   Childhood Hepatocellular Carcinoma;   HCC;   Hepatocellular Cancer;   Hepatocellular Cancers;   Hepatocellular Carcinoma, Childhood Type, Somatic;   Hepatocellular Carcinomas;   Hepatoma;   Hepatomas;   LCC;   Liver Cell Carcinoma;   adult Hepatoma;   adult liver cancers;   adult liver cell carcinoma;   adult primary hepatocellular carcinoma;   liver cell carcinomas
 narrow_synonym: HEPATOBLASTOMA CAUSED BY SOMATIC MUTATION;   HEPATOMA HEPATOBLASTOMA
 primary_id: MESH:D006528
 alt_id: OMIM:114550
 xref: ICD-O:M8170/3;   NCI:C129298;   NCI:C3099;   NCI:C38756;   NCI:C60416;   ORDO:88673
For additional species annotation, visit the Alliance of Genome Resources.


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hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:liver:
CTD
RGD
PMID:15509519 RGD:1358261 NCBI chr 5:62,406,928...62,483,690
Ensembl chr 5:62,438,017...62,485,537
JBrowse link
G AADAT aminoadipate aminotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:19,768,816...19,792,254
Ensembl chr14:19,768,499...19,791,938
JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 severity ISO mRNA:decreased expression:liver (human) RGD PMID:16941710, PMID:30580964 RGD:1598532, RGD:24922199 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492
JBrowse link
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 susceptibility ISO DNA:polymorphism: : c.1465C > T(human)
DNA:polymorphism: :c.3751G>A(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17510421, PMID:23488625, PMID:24175826, PMID:25625052 RGD:11041138, RGD:14700904, RGD:14700905 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022477 NCBI chr 9:93,171,371...93,262,124 JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO mRNA:increased expression:liver RGD PMID:25842354 RGD:11535155 NCBI chr12:26,920,764...26,978,389
Ensembl chr12:26,920,821...26,978,363
JBrowse link
G ABCE1 ATP binding cassette subfamily E member 1 ISO mRNA:increased expression:liver (human) RGD PMID:21932399 RGD:11041873 NCBI chr 8:83,302,055...83,353,208
Ensembl chr 8:83,299,314...83,353,110
JBrowse link
G ACACA acetyl-CoA carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,449...38,875,134
JBrowse link
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16328049 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G ACER3 alkaline ceramidase 3 disease_progression ISO RGD PMID:30097213 RGD:35673325 NCBI chr 9:10,985,078...11,167,386
Ensembl chr 9:10,951,561...11,165,493
JBrowse link
G ACLY ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr12:20,796,678...20,841,301
Ensembl chr12:20,796,749...20,841,298
JBrowse link
G ACO2 aconitase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 5:7,014,383...7,071,023
Ensembl chr 5:7,002,124...7,070,999
JBrowse link
G ACOX1 acyl-CoA oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12771043, PMID:15565109 NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,428,360...5,479,544
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr  X:89,760,863...89,838,103
Ensembl chr  X:89,760,865...89,837,678
JBrowse link
G ACTB actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144, PMID:21472284 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356
JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19514085 NCBI chr13:190,277,175...190,285,957
Ensembl chr13:190,276,424...190,286,205
JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:273,022,014...273,066,916
Ensembl chr 1:273,022,000...273,056,039
JBrowse link
G ADD1 adducin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,177...1,710,661
JBrowse link
G ADGRG7 adhesion G protein-coupled receptor G7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:158,334,535...158,402,752
Ensembl chr13:158,338,849...158,408,525
JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:121,225,485...121,259,262
NCBI chr  X:98,582,002...98,583,002
Ensembl chr 8:121,225,656...121,261,747
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing susceptibility ISO DNA:SNP:intron:+276T>G (rs1501299) (human) RGD PMID:23740135 RGD:14401720 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:10,623,391...10,733,378
Ensembl chr14:10,626,293...10,733,069
JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:45,760,966...45,762,306
Ensembl chr 3:45,758,268...45,764,178
JBrowse link
G AFP alpha fetoprotein severity ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (human)
CTD
RGD
PMID:9029167, PMID:15276417, PMID:22147961, PMID:24012840, PMID:28284560 RGD:14401581 NCBI chr 8:69,677,690...69,698,864
Ensembl chr 8:69,677,684...69,698,864
JBrowse link
G AK3 adenylate kinase 3 ISO protein:decreased expression:liver RGD PMID:17203974 RGD:13842477 NCBI chr 1:217,236,561...217,263,144
Ensembl chr 1:217,236,482...217,261,370
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B ISO protein:increased expression:liver (human)
protein:increased expression:liver (rat)
RGD PMID:19422879, PMID:21683810 RGD:5509919, RGD:8548685 NCBI chr18:14,593,516...14,752,316
Ensembl chr18:14,593,548...14,752,310
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:17611497, PMID:18256540, PMID:18392055, PMID:18504432, PMID:18611285, PMID:19418217, PMID:19487299, PMID:19853286, PMID:20233444, PMID:20453058, PMID:21464312, PMID:21512767, PMID:21793738, PMID:22538770, PMID:22610119, PMID:22722201, PMID:22722839, PMID:22980975, PMID:23237847, PMID:23348505, PMID:23700467, PMID:23728071, PMID:23934607, PMID:24190505, PMID:24657128, PMID:25157968, PMID:26619011, PMID:28492532
G AKT2 AKT serine/threonine kinase 2 ISO protein:increased phosphorylation:liver cancer cell (rat) RGD PMID:19309364 RGD:2313299 NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,789...48,587,919
JBrowse link
G ALB albumin susceptibility ISO associated with hepatitis C;protein:decreased expression:serum RGD PMID:23892757, PMID:29040987 RGD:11035269, RGD:14694841 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,718,304
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member no_association
severity
susceptibility
ISO DNA:missense mutation:exon 12: (human)
mRNA, protein:decreased expression:liver (human)
associated with hepatitis B;DNA;missense mutation, haplotype:cds: (rs671) (human)
DNA:missense mutation:cds: (rs671) (human)
protein:decreased expression: liver (human)
associated with alcohol use disorder;DNA:missense mutation:cds: (human)
associated with alcoholic liver cirrhosis;DNA:missense mutation:cds:p.E487K (human)
associated with hepatitis C:DNA:SNP:exon 12 (human)
DNA:missense mutation:cds, exon 12:p.E487K (human)
RGD PMID:1916152, PMID:10737710, PMID:12940444, PMID:18439068, PMID:25778454, PMID:26150517, PMID:26827895, PMID:28027570, PMID:29765251 RGD:11054822, RGD:14696699, RGD:14696778, RGD:14696779, RGD:14700899, RGD:15036809, RGD:15042857, RGD:15042859, RGD:15042862 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C ISO mRNA:increased expression:liver RGD PMID:3830170 RGD:2301136 NCBI chr12:44,823,376...44,827,273
Ensembl chr12:44,808,341...44,848,519
JBrowse link
G ANGPTL6 angiopoietin like 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:68,947,067...68,958,820
Ensembl chr 2:68,947,071...68,958,766
JBrowse link
G ANLN anillin actin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:37,647,952...37,710,939
Ensembl chr18:37,647,961...37,709,263
JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 treatment ISO RGD PMID:20650339 RGD:9684932 NCBI chr 3:73,157,744...73,398,379
Ensembl chr 3:73,157,752...73,398,345
JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 3:72,623,311...72,654,591
Ensembl chr 3:72,622,357...72,793,636
JBrowse link
G APC APC regulator of WNT signaling pathway ISO OMIM NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912
JBrowse link
G APCS amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 4:90,900,585...90,901,854
Ensembl chr 4:90,898,686...90,901,875
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25109342 NCBI chr 7:78,451,845...78,454,938
Ensembl chr 7:78,451,851...78,454,938
JBrowse link
G APLN apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,748...106,246,378
JBrowse link
G APOA1 apolipoprotein A1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma (human)
CTD
RGD
PMID:21472284, PMID:23935864 RGD:25671438 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G APOE apolipoprotein E ISO protein:increased expression:liver, serum (mouse) RGD PMID:21644509 RGD:6903288 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
G APOF apolipoprotein F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:21,759,670...21,760,753
Ensembl chr 5:21,750,067...21,751,157
Ensembl chr 5:21,750,067...21,751,157
JBrowse link
G APRT adenine phosphoribosyltransferase ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr 6:890,272...893,278
Ensembl chr 6:890,831...893,277
JBrowse link
G AR androgen receptor ISO CTD Direct Evidence: therapeutic CTD PMID:18639551 NCBI chr  X:53,609,113...53,806,778
Ensembl chr  X:53,609,176...53,805,578
JBrowse link
G ARG1 arginase 1 ISO RGD PMID:17210712 RGD:4140476 NCBI chr 1:32,006,035...32,028,983
Ensembl chr 1:32,006,038...32,028,986
JBrowse link
G ARHGAP11A Rho GTPase activating protein 11A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:136,497,436...136,522,355 JBrowse link
G ARHGEF39 Rho guanine nucleotide exchange factor 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:236,383,684...236,387,705
Ensembl chr 1:236,377,802...236,387,667
JBrowse link
G ARID1A AT-rich interaction domain 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517, PMID:22634756, PMID:22922871 NCBI chr 6:84,049,729...84,124,302
Ensembl chr 6:84,049,365...84,123,384
JBrowse link
G ARID1B AT-rich interaction domain 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 1:9,791,627...10,227,381
Ensembl chr 1:9,791,629...10,227,947
JBrowse link
G ARID2 AT-rich interaction domain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822264, PMID:22634756 NCBI chr 5:76,637,385...76,800,155
Ensembl chr 5:76,637,202...76,847,316
JBrowse link
G ASF1B anti-silencing function 1B histone chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:65,063,186...65,072,681
Ensembl chr 2:65,062,766...65,072,681
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) ISO protein:increased activity:serum (rat) RGD PMID:10081 RGD:2316006 NCBI chr 9:77,318,341...77,336,290
Ensembl chr 9:77,318,213...77,509,020
JBrowse link
G ASPG asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560
G ASPM assembly factor for spindle microtubules disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18676753, PMID:28284560 RGD:13439743 NCBI chr10:19,971,516...20,039,680
Ensembl chr10:19,975,189...20,039,623
JBrowse link
G ASS1 argininosuccinate synthase 1 ISO RGD PMID:12359751 RGD:4140479 NCBI chr 1:270,531,434...270,586,364
Ensembl chr 1:270,531,589...270,586,361
JBrowse link
G ATG7 autophagy related 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29191453 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,660
JBrowse link
G ATM ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19919837 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,554
JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b ISO associated with hepatitis C RGD PMID:18932288 RGD:14696822 NCBI chr 4:108,896,063...108,907,626
Ensembl chr 4:108,896,056...108,907,805
JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr12:6,241,467...6,247,344 JBrowse link
G AURKA aurora kinase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:56,954,838...56,972,435 JBrowse link
G AURKB aurora kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:53,410,833...53,426,165
Ensembl chr12:53,410,176...53,423,225
JBrowse link
G AXIN1 axin 1 ISO OMIM NCBI chr 3:41,344,908...41,393,999
Ensembl chr 3:41,337,071...41,393,997
JBrowse link
G AZIN1 antizyme inhibitor 1 disease_progression ISO RNA:increased editing:liver RGD PMID:23291631 RGD:14700705 NCBI chr 4:34,221,368...34,257,261
Ensembl chr 4:34,209,008...34,257,136
JBrowse link
G BCL2L1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:10629087, PMID:11509945 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,141...35,415,359
JBrowse link
G BCO2 beta-carotene oxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:39,864,136...39,916,491
Ensembl chr 9:39,864,114...39,927,801
JBrowse link
G BID BH3 interacting domain death agonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:15289866 NCBI chr 5:69,849,007...69,874,647
Ensembl chr 5:69,849,002...69,875,853
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16086872, PMID:20514400 NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,237...3,755,188
JBrowse link
G BLZF1 basic leucine zipper nuclear factor 1 disease_progression ISO RGD PMID:26342799 RGD:14398326 NCBI chr 4:81,597,312...81,639,788
Ensembl chr 4:81,571,290...81,639,558
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger treatment ISO RGD PMID:26919246 RGD:14928318 NCBI chr10:52,586,089...52,596,154 JBrowse link
G BMPER BMP binding endothelial regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:39,417,830...39,664,010
Ensembl chr18:39,412,838...39,950,737
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27222248 NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,959...9,132,553
JBrowse link
G BTG2 BTG anti-proliferation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18393292 NCBI chr 9:64,033,853...64,037,795 JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:45,585,188...45,623,240
Ensembl chr 3:45,585,226...45,624,543
JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:131,093,026...131,143,840 JBrowse link
G C3 complement C3 ISO RGD PMID:23245919 RGD:11040806 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,499...72,528,112
JBrowse link
G C9 complement C9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144, PMID:28284560 NCBI chr16:24,521,318...24,575,939
Ensembl chr16:24,525,394...24,588,030
JBrowse link
G CA2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 4:51,194,686...51,211,436
Ensembl chr 4:51,193,755...51,211,259
JBrowse link
G CAB39 calcium binding protein 39 disease_progression ISO RGD PMID:28605041 RGD:14398832 NCBI chr15:131,492,575...131,584,963
Ensembl chr15:131,492,650...131,600,454
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO DNA:amplification:cds (rat)
mRNA:increased expression:liver
RGD PMID:2888462, PMID:2914957 RGD:2303530, RGD:5132587 NCBI chr 3:111,887,017...111,914,511
Ensembl chr 3:111,887,020...111,914,495
JBrowse link
G CADM1 cell adhesion molecule 1 ISO DNA, mRNA, protein:hypermethylation, decreased expression:promoter:liver RGD PMID:17428255 RGD:2289095 NCBI chr 9:42,644,487...42,984,934
Ensembl chr 9:42,634,855...42,984,879
JBrowse link
G CADM2 cell adhesion molecule 2 disease_progression ISO mRNA, protein:decreased expression:liver RGD PMID:24240726 RGD:15092075 NCBI chr13:169,681,947...170,753,114
Ensembl chr13:169,688,940...170,752,425
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:23651211 RGD:18337283 NCBI chr 6:78,730,204...78,734,232 JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:13,211,110...13,350,966
Ensembl chr 7:13,211,573...13,350,962
JBrowse link
G CAPN3 calpain 3 ISO mRNA:decreased expression:skeletal muscle RGD PMID:10806331 RGD:1600777 NCBI chr 1:128,960,117...129,013,508
Ensembl chr 1:128,960,121...129,013,547
JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA,protein:increased expression:liver: RGD PMID:23912631 RGD:9586718 NCBI chr 2:69,602,121...69,644,862
Ensembl chr 2:69,602,130...69,644,862
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29133031 RGD:13782296 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CASP8 caspase 8 treatment
severity
ISO associated with hepatitis B;DNA:insertion/deletion:promoter: (rs3834129) (human) OMIM
RGD
PMID:28643196, PMID:29133031 RGD:13782296, RGD:14695027 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,470
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:29133031 RGD:13782296 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,515...74,730,092
JBrowse link
G CAT catalase disease_progression ISO associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-262T>C (human) RGD PMID:21907168 RGD:27095879 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CBR1 carbonyl reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21056497 NCBI chr13:199,617,406...199,622,407
Ensembl chr13:199,617,318...199,622,405
JBrowse link
G CBX4 chromobox 4 disease_progression ISO protein:increased expression:cytoplasm: RGD PMID:23943028, PMID:24838576 RGD:9586738, RGD:9586739 NCBI chr12:2,520,913...2,527,245
Ensembl chr12:2,520,698...2,527,241
JBrowse link
G CBX7 chromobox 7 ISO mRNA:decreased expression:liver RGD PMID:22041561 RGD:9587355 NCBI chr 5:9,070,312...9,090,467 JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:161,320,627...161,556,539
Ensembl chr 1:161,321,273...161,556,537
JBrowse link
G CCL14 C-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:39,611,887...39,616,050
Ensembl chr12:39,611,868...39,616,159
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 treatment ISO RNA:increased expression:liver RGD PMID:12679798, PMID:22402625, PMID:27980102 RGD:14995459, RGD:14995468, RGD:14995927 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCL3L1 chemokine (C-C motif) ligand 3-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr12:39,491,999...39,493,345
Ensembl chr12:39,491,885...39,493,370
JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility
treatment
ISO DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
associated with alcoholic liver cirrhosis;DNA:SNP:promoter:-403G>A(human)
RGD PMID:21610221, PMID:22374185, PMID:28011329 RGD:14995306, RGD:14995333, RGD:14995338 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
JBrowse link
G CCN1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17699798 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,404...130,395,150
JBrowse link
G CCNA1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619 NCBI chr11:12,396,149...12,405,357
Ensembl chr11:12,396,301...12,405,353
JBrowse link
G CCNB1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,381
JBrowse link
G CCNB2 cyclin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:112,907,047...112,942,218
Ensembl chr 1:112,907,047...112,942,219
JBrowse link
G CCND1 cyclin D1 susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNP:splice-site mutation:870G>A (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12029619, PMID:19919837, PMID:22649188, PMID:25822088, PMID:25851350, PMID:26189965 RGD:14401586 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CCNE1 cyclin E1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12029619, PMID:17196522, PMID:22634754 RGD:2289277 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,366
JBrowse link
G CCNF cyclin F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:39,585,597...39,603,088
Ensembl chr 3:39,585,602...39,603,083
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,220...29,233,960
JBrowse link
G CD163 CD163 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:63,300,200...63,334,497
Ensembl chr 5:63,300,146...63,334,498
JBrowse link
G CD274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22396772 NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,047...216,792,724
JBrowse link
G CD276 CD276 molecule ISO CTD Direct Evidence: therapeutic CTD PMID:16217749 NCBI chr 7:59,703,283...59,733,910
Ensembl chr 7:59,629,638...59,733,778
JBrowse link
G CD34 CD34 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:134,912,793...134,937,763
Ensembl chr 9:134,913,121...134,937,762
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:19016771 RGD:2313413 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CD5L CD5 molecule like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:92,394,535...92,412,146 JBrowse link
G CDC20 cell division cycle 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:167,886,266...167,890,587
Ensembl chr 6:167,886,270...167,890,583
JBrowse link
G CDC25C cell division cycle 25C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:140,289,156...140,323,696
Ensembl chr 2:140,263,301...140,324,425
JBrowse link
G CDC45 cell division cycle 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:51,133,111...51,158,604
Ensembl chr14:51,133,408...51,158,606
JBrowse link
G CDC6 cell division cycle 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:22,101,281...22,118,441
Ensembl chr12:22,101,282...22,118,593
JBrowse link
G CDCA2 cell division cycle associated 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:9,517,763...9,571,303
Ensembl chr14:9,518,866...9,566,588
JBrowse link
G CDCA3 cell division cycle associated 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:63,858,905...63,861,902
Ensembl chr 5:63,859,538...63,864,269
JBrowse link
G CDCA5 cell division cycle associated 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:7,103,648...7,112,772
Ensembl chr 2:7,102,982...7,113,202
JBrowse link
G CDCA8 cell division cycle associated 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:93,750,694...93,764,845
Ensembl chr 6:93,750,687...93,765,483
JBrowse link
G CDH1 cadherin 1 severity ISO DNA:hypermethylation
protein:decreased expression:liver
mRNA:increased expression:liver
RGD PMID:17295234, PMID:18837082, PMID:24840851, PMID:30697077 RGD:14402045, RGD:14402046, RGD:14402047, RGD:2289638 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
JBrowse link
G CDH13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18425332, PMID:18553387, PMID:28284560 NCBI chr 6:4,809,752...5,832,188
Ensembl chr 6:4,808,255...5,832,188
JBrowse link
G CDK1 cyclin dependent kinase 1 ISO protein:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19136513, PMID:28284560 RGD:2316317 NCBI chr14:64,233,945...64,255,290
Ensembl chr14:64,233,988...64,395,453
JBrowse link
G CDK14 cyclin dependent kinase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr 9:70,678,012...71,310,253
Ensembl chr 9:70,499,828...71,310,244
JBrowse link
G CDK4 cyclin dependent kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr 5:23,039,206...23,041,959
Ensembl chr 5:23,038,889...23,042,061
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20698225 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:161,160,290...161,166,681
Ensembl chr 6:161,160,291...161,166,527
JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 treatment
severity
ISO associated with alcoholism; protein:increased expression:liver
mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver
RGD
CTD
PMID:22390936, PMID:23292002, PMID:27314282, PMID:28284560 RGD:15090800, RGD:15090801, RGD:15090802 NCBI chr 1:183,792,606...183,809,178
Ensembl chr 1:183,792,673...183,809,174
JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:893,377...897,706 JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16288022, PMID:21785164 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,203...43,085,836
JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr17:51,722,633...51,723,673
Ensembl chr17:51,722,426...51,724,305
JBrowse link
G CEBPD CCAAT enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 4:79,872,863...79,874,481
Ensembl chr 4:79,872,421...79,873,989
JBrowse link
G CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:31,331,563...31,357,374
Ensembl chr13:31,331,564...31,357,270
JBrowse link
G CENPA centromere protein A ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
CTD
RGD
PMID:21956590, PMID:28284560 RGD:36947377 NCBI chr 3:112,263,912...112,272,638
Ensembl chr 3:112,263,913...112,272,621
JBrowse link
G CENPE centromere protein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:117,888,968...117,965,325
Ensembl chr 8:117,889,009...117,965,792
JBrowse link
G CENPF centromere protein F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:128,948,386...129,012,241
Ensembl chr 9:128,948,497...129,012,218
JBrowse link
G CENPM centromere protein M ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:6,677,607...6,690,322
Ensembl chr 5:6,677,716...6,690,308
JBrowse link
G CENPU centromere protein U ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:45,818,562...45,851,461
Ensembl chr15:45,818,943...45,851,441
JBrowse link
G CENPW centromere protein W ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:36,405,693...36,695,989
Ensembl chr 1:36,417,053...36,695,954
JBrowse link
G CEP131 centrosomal protein 131 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:1,537,900...1,556,931
Ensembl chr12:1,538,326...1,556,930
JBrowse link
G CEP55 centrosomal protein 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:104,957,256...104,980,690
Ensembl chr14:104,957,311...104,987,638
JBrowse link
G CFP complement factor properdin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:42,145,754...42,152,879
Ensembl chr  X:42,143,805...42,174,939
JBrowse link
G CHAF1B chromatin assembly factor 1 subunit B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:200,048,096...200,074,902
Ensembl chr13:200,048,131...200,072,556
JBrowse link
G CKAP2L cytoskeleton associated protein 2 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:43,736,526...43,772,995
Ensembl chr 3:43,736,744...43,772,974
JBrowse link
G CLDN1 claudin 1 severity ISO protein:increased expression:liver (human)
associated with liver cirrhosis;protein:increased expression:liver (human)
protein:decreased expression:liver (human)
RGD PMID:17270214, PMID:24696415, PMID:24815833 RGD:26884345, RGD:26884348, RGD:26884352 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,767...127,730,657
JBrowse link
G CLEC1B C-type lectin domain family 1 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:61,889,874...61,896,964
Ensembl chr 5:61,889,930...61,896,760
JBrowse link
G CLEC4G C-type lectin domain family 4 member G ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:71,433,406...71,436,570 JBrowse link
G CLTRN collectrin, amino acid transport regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:12,183,793...12,215,474 JBrowse link
G CNDP1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:149,523,983...149,564,728
Ensembl chr 1:149,521,510...149,562,528
JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:26619011 NCBI chr15:120,590,354...120,622,203
Ensembl chr15:120,590,641...120,669,825
JBrowse link
G CNTNAP4 contactin associated protein family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:11,316,534...11,589,628 JBrowse link
G COL15A1 collagen type XV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:240,718,128...240,829,188
Ensembl chr 1:240,653,017...240,829,188
JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain severity ISO Protein:increased expression RGD PMID:15739185 RGD:1600906 NCBI chr13:207,907,835...207,984,082
Ensembl chr13:207,907,857...207,985,181
JBrowse link
G COLEC10 collectin subfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:19,692,990...20,143,740
Ensembl chr 4:19,692,826...19,744,135
JBrowse link
G COMT catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,133...51,403,998
JBrowse link
G COPS5 COP9 signalosome subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20698225 NCBI chr 4:67,740,528...67,758,153
Ensembl chr 4:67,738,939...67,758,150
JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19229483 NCBI chr13:89,396,713...89,463,540
Ensembl chr13:89,396,685...89,463,538
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:103,675,164...103,871,245
Ensembl chr14:103,675,175...103,871,227
JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar PMID:21390126, PMID:21680795, PMID:21796119, PMID:22832583, PMID:23334668, PMID:23685749, PMID:23778141, PMID:26087898, PMID:26619011, PMID:27257180, PMID:28492532, PMID:29551561 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,230
JBrowse link
G CRHBP corticotropin releasing hormone binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:85,814,399...85,830,598
Ensembl chr 2:85,816,815...85,831,180
JBrowse link
G CRP C-reactive protein, pentraxin-related ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO RGD PMID:12731087 RGD:10450243 NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155
JBrowse link
G CSK C-terminal Src kinase ISO protein:decreased expression:liver RGD PMID:9918913 RGD:5134372 NCBI chr 7:58,736,473...58,755,034
Ensembl chr 7:58,736,529...58,755,260
JBrowse link
G CSMD1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:34,361,722...36,243,762
Ensembl chr15:34,364,050...35,023,152
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:57,949,182...57,988,602
Ensembl chr 7:57,949,455...57,988,337
JBrowse link
G CSRNP1 cysteine and serine rich nuclear protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:23,833,130...23,845,198
Ensembl chr13:23,833,133...23,845,215
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility ISO DNA:SNPs: :rs231775,rs231725(human)
protein:increased expression:CD4+ and CD8+ T cells:
RGD PMID:23432218, PMID:28648905 RGD:14398741, RGD:14398742 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,926...107,289,103
JBrowse link
G CTNNB1 catenin beta 1 susceptibility
severity
ISO associated with Hepatitis B, Chronic,DNA:SNP, haplotype: :rs3864004 (human)
DNA:Mutations:exon:
associated with hepatitis B;DNA:SNPs: :rs3864004,rs11564475(human)
OMIM
RGD
PMID:19101982, PMID:26968103, PMID:28328801 RGD:14402039, RGD:14402040, RGD:14402052 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,137,173...25,208,311
JBrowse link
G CTSB cathepsin B ISO RGD PMID:15641152 RGD:2315605 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,034,737
JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:1,188,548...1,197,642
Ensembl chr 2:1,188,549...1,197,635
JBrowse link
G CTSL cathepsin L ISO RGD PMID:15641152 RGD:2315605 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618
JBrowse link
G CUNH14orf180 chromosome unknown C14orf180 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560
G CXCL10 C-X-C motif chemokine ligand 10 disease_progression
treatment
ISO RGD PMID:27245433, PMID:28592115, PMID:28638480 RGD:27095889, RGD:27095898, RGD:27095899 NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144, PMID:28284560 NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,429...91,552,766
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:137,803,988...137,813,118
Ensembl chr 2:137,803,988...137,812,914
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 susceptibility
disease_progression
ISO CTD Direct Evidence: therapeutic
mRNA:increased expression:liver (human)
DNA:SNPs, haplotype:multiple
protein:increased expression:liver (human)
CTD
RGD
PMID:12432545, PMID:24381110, PMID:26078356, PMID:30523154 RGD:11526468, RGD:26884364, RGD:26884366 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21109933 NCBI chr 6:34,058,091...34,121,939
Ensembl chr 6:34,059,941...34,121,272
JBrowse link
G CYP17A1 cytochrome P450 17A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041
JBrowse link
G CYP1A1 cytochrome P450 1A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,780,105...58,809,755
JBrowse link
G CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100
JBrowse link
G CYP2B22 cytochrome P450 2B22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,413
JBrowse link
G CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 ISO associated with alcohol dependence
DNA, mRNA:SNP, Decreased expression:liver: rs2031920 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15162526, PMID:20364586, PMID:29765251 RGD:14700882, RGD:14700899 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,818
JBrowse link
G CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:41,345,011...41,425,854
Ensembl chr 7:41,344,804...41,426,343
JBrowse link
G DBH dopamine beta-hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,400...273,225,558
JBrowse link
G DCN decorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:91,678,601...91,713,925
Ensembl chr 5:91,678,608...91,714,235
JBrowse link
G DEPDC1 DEP domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:144,157,569...144,183,977
Ensembl chr 6:144,157,587...144,185,968
JBrowse link
G DEPDC1B DEP domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:39,466,496...39,558,750
Ensembl chr16:39,466,494...39,680,173
JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21725309 NCBI chr14:48,421,788...48,523,530 JBrowse link
G DIPK2B divergent protein kinase domain 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:40,179,289...40,223,011
Ensembl chr  X:40,178,969...40,222,542
JBrowse link
G DIRAS3 DIRAS family GTPase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:144,576,342...144,578,820
Ensembl chr 6:144,558,104...144,578,820
JBrowse link
G DLGAP5 DLG associated protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:184,500,791...184,550,028
Ensembl chr 1:184,499,914...184,550,020
JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:146,990,115...147,161,010
Ensembl chr 6:146,989,325...147,155,132
JBrowse link
G DNASE1L3 deoxyribonuclease 1 like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:39,958,384...39,976,114
Ensembl chr13:39,954,804...39,975,946
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA, protein:increased expression:liver RGD PMID:11844796 RGD:2289670 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,564...69,029,919
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO mRNA, protein:increased expression:liver
protein:increased expression:liver:
RGD PMID:11844796, PMID:15885882 RGD:2289670, RGD:9588598 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,609,139
JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA:increased expression:liver:
mRNA, protein:increased expression:liver
RGD PMID:11844796, PMID:15885882 RGD:2289670, RGD:9588598 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,332,801...36,386,074
JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18019677 NCBI chr 4:119,931,471...120,712,461
Ensembl chr 4:119,931,458...120,712,462
JBrowse link
G DSN1 DSN1 component of MIS12 kinetochore complex disease_progression ISO RGD PMID:30136646 RGD:27372884 NCBI chr17:39,992,769...40,017,388
Ensembl chr17:39,990,623...40,017,500
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:131,225,840...131,275,426
Ensembl chr 9:131,182,423...131,275,451
JBrowse link
G DYNLRB1 dynein light chain roadblock-type 1 ISO RGD PMID:11750132 RGD:13208527 NCBI chr17:37,923,451...37,941,851
Ensembl chr17:37,923,475...37,945,880
JBrowse link
G DYNLRB2 dynein light chain roadblock-type 2 ISO RGD PMID:11750132 RGD:13208527 NCBI chr 6:7,650,444...7,661,380
Ensembl chr 6:7,650,444...7,661,320
JBrowse link
G E2F1 E2F transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619, PMID:15565109, PMID:28284560 NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,598...37,189,841
JBrowse link
G E2F8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:40,178,182...40,194,932
Ensembl chr 2:40,178,176...40,194,941
JBrowse link
G EAF2 ELL associated factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr13:138,632,541...138,681,607
Ensembl chr13:138,637,086...138,681,613
JBrowse link
G ECM1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:98,615,776...98,633,081
Ensembl chr 4:98,615,778...98,633,515
JBrowse link
G ECT2 epithelial cell transforming 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:111,248,215...111,310,746
Ensembl chr13:111,248,134...111,314,828
JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 disease_progression ISO protein:decreased expression:liver: RGD PMID:23936443 RGD:10401793 NCBI chr 3:85,407,677...85,473,251
Ensembl chr 3:85,268,311...85,473,254
JBrowse link
G EGF epidermal growth factor susceptibility ISO associated with hepatitis B;DNA:SNP:exon: (rs11569017) (human)
associated with liver cirrhosis;DNA:SNP:5'UTR: (rs4444903) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9029167, PMID:18167406, PMID:23790025 RGD:14695013, RGD:14695014 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,365...112,330,046
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029167 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,478,882
JBrowse link
G EGR1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296
JBrowse link
G EGR2 early growth response 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:66,280,665...66,291,308
Ensembl chr14:66,284,577...66,291,306
JBrowse link
G EHD3 EH domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:108,103,631...108,135,161
Ensembl chr 3:108,103,632...108,134,889
JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H ISO CTD Direct Evidence: marker/mechanism CTD PMID:14578863 NCBI chr 4:21,955,026...22,053,683
Ensembl chr 4:21,955,042...22,058,707
JBrowse link
G ENG endoglin ISO protein:increased expression:liver (rat) RGD PMID:20368095 RGD:7257538 NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,306,120...268,343,827
JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,882...69,401,117
JBrowse link
G EP300 E1A binding protein p300 ISO protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G EPCAM epithelial cell adhesion molecule severity ISO protein:increased expression:liver RGD PMID:24616575 RGD:14695007 NCBI chr 3:93,169,800...93,185,221
Ensembl chr 3:93,168,852...93,185,653
JBrowse link
G EPHX1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7892276 NCBI chr10:13,757,489...13,773,071
Ensembl chr10:13,735,170...13,773,071
JBrowse link
G EPS8L3 EPS8 like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:110,311,533...110,326,999
Ensembl chr 4:110,311,507...110,329,568
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNPs:exon 23: p.K751Q (rs13181) (human)
DNA:SNPs:exon 23: p.K751Q (human)
RGD PMID:19919686, PMID:25531380, PMID:28598207 RGD:25671459, RGD:25671460, RGD:25671461 NCBI chr 6:51,734,318...51,757,508
Ensembl chr 6:51,734,319...51,779,624
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,997,426
JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr14:39,687,028...39,695,748
Ensembl chr14:39,687,029...39,695,752
JBrowse link
G ESM1 endothelial cell specific molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:34,184,255...34,193,877
Ensembl chr16:34,183,546...34,194,578
JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144, PMID:28284560 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G ETFA electron transfer flavoprotein subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 7:56,450,508...56,540,275
Ensembl chr 7:56,440,620...56,540,253
JBrowse link
G EXO1 exonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:15,317,555...15,360,593
Ensembl chr10:15,317,581...15,359,839
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:24211739, PMID:28284560 RGD:10755339 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,384,995...109,450,941
JBrowse link
G F2 coagulation factor II, thrombin severity ISO CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis;protein:altered expression, altered processing:liver (human)
CTD
RGD
PMID:2821104, PMID:7620113 RGD:14975114 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,451...15,819,138
JBrowse link
G FABP5 fatty acid binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 4:55,277,831...55,282,585
Ensembl chr 4:55,275,202...55,282,908
JBrowse link
G FAM111B family with sequence similarity 111 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:12,268,692...12,279,386
Ensembl chr 2:12,268,694...12,279,560
JBrowse link
G FAM180A family with sequence similarity 180 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:13,574,024...13,589,117
Ensembl chr18:13,575,535...13,591,743
JBrowse link
G FAM83D family with sequence similarity 83 member D ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:41,868,982...41,892,222
Ensembl chr17:41,869,051...41,895,625
JBrowse link
G FANCD2 FA complementation group D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:66,241,951...66,308,601
Ensembl chr13:66,241,673...66,310,436
JBrowse link
G FANCI FA complementation group I ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:54,811,024...54,889,992
Ensembl chr 7:54,744,742...54,890,997
JBrowse link
G FAS Fas cell surface death receptor treatment ISO protein:increased expression:liver: RGD PMID:11274632, PMID:29634416, PMID:30737368 RGD:13792608, RGD:14700677, RGD:14700700 NCBI chr14:100,927,305...100,954,781 JBrowse link
G FASLG Fas ligand (TNF superfamily, member 6) ISO protein:increased expression:liver: RGD PMID:11274632 RGD:14700677 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,475
JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831, PMID:15543204, PMID:21147110 NCBI chr12:922,405...937,560
Ensembl chr12:920,507...937,559
JBrowse link
G FATE1 fetal and adult testis expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15580283 NCBI chr  X:123,106,086...123,113,178
Ensembl chr  X:123,099,746...123,113,173
JBrowse link
G FBP1 fructose-bisphosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22039417 NCBI chr10:27,588,609...27,622,225
Ensembl chr10:27,588,582...27,623,077
JBrowse link
G FBXL18 F-box and leucine rich repeat protein 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:4,031,784...4,079,605
Ensembl chr 3:4,033,580...4,079,558
JBrowse link
G FCN1 ficolin (collagen/fibrinogen domain containing) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:274,125,666...274,132,917 JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr14:14,976,259...15,010,701
Ensembl chr14:14,967,273...15,104,179
JBrowse link
G FGF19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 2:3,583,027...3,586,985
Ensembl chr 2:3,583,027...3,587,825
JBrowse link
G FGF3 fibroblast growth factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 2:3,489,208...3,496,532
Ensembl chr 2:3,489,208...3,496,532
JBrowse link
G FGF4 fibroblast growth factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr 2:3,527,113...3,529,011
Ensembl chr 2:3,527,113...3,528,873
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 treatment ISO ClinVar Annotator: match by term: Hepatocellular carcinoma RGD
ClinVar
PMID:16452204, PMID:20155451, PMID:21573021, PMID:25705862, PMID:26619011, PMID:26942290 RGD:25330358, RGD:25440476, RGD:25440478 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,746
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 severity ISO associated with hepatitis B;DNA:SNPs: promoter, intron:rs308379, rs1219648 (human) RGD PMID:30952770 RGD:38501096 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,710...131,579,703
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO RGD PMID:12112319 RGD:632723 NCBI chr13:41,443,963...42,884,799
Ensembl chr13:41,443,965...42,228,680
JBrowse link
G FLVCR1 FLVCR heme transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:130,543,911...130,570,486
Ensembl chr 9:130,539,854...130,570,702
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029167, PMID:28284560 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:51,836,780...51,844,531
Ensembl chr 6:51,837,719...51,844,531
JBrowse link
G FOXM1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15082532, PMID:17173139, PMID:28284560 NCBI chr 5:67,246,219...67,263,215
Ensembl chr 5:67,245,694...67,263,211
Ensembl chr 5:67,245,694...67,263,211
JBrowse link
G FOXO1 forkhead box O1 ISO mRNA:decreased expression:liver RGD PMID:28972178 RGD:14401599 NCBI chr11:15,317,222...15,410,059
Ensembl chr11:15,317,124...15,410,473
JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:25156538 RGD:9587823 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,347,849...52,974,261
JBrowse link
G FOXP3 forkhead box P3 ISO protein:increased expression:liver RGD PMID:21086571 RGD:38548919 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,782...43,328,735
JBrowse link
G FST follistatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203361, PMID:19363144 NCBI chr16:32,806,341...32,811,382
Ensembl chr16:32,805,874...32,811,421
JBrowse link
G FTH1 ferritin heavy chain 1 ISO mRNA:increased expression:liver (rat) RGD PMID:9054589 RGD:632698 NCBI chr 2:9,535,051...9,537,979 JBrowse link
G G6PC glucose-6-phosphatase catalytic subunit treatment ISO associated with Glycogen Storage Disease IA, human gene in a mouse model RGD PMID:28096054 RGD:14695537 NCBI chr12:19,965,885...19,975,783
Ensembl chr12:19,962,934...19,976,050
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:25473368 RGD:10449118 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,025,257...125,041,033
JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:64,049,665...64,059,644
Ensembl chr 6:64,049,675...64,059,640
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16767786, PMID:21472284 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,680...64,133,991
JBrowse link
G GBA3 glucosylceramidase beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:16,897,275...17,012,886
Ensembl chr 8:16,897,317...17,137,315
JBrowse link
G GC GC vitamin D binding protein susceptibility ISO protein:increased expression:liver
associated with Hepatitis B, Chronic;DNA:SNP: :rs7041(human)
RGD PMID:21683810, PMID:25541958 RGD:14402025, RGD:5509919 NCBI chr 8:68,326,293...68,360,262
Ensembl chr 8:68,326,301...68,360,262
JBrowse link
G GDF15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20512989 NCBI chr 2:59,409,035...59,411,356
Ensembl chr 2:59,408,904...59,411,358
JBrowse link
G GDF2 growth differentiation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23936038, PMID:28284560 NCBI chr14:88,506,083...88,513,416
Ensembl chr14:88,507,397...88,513,376
JBrowse link
G GHR growth hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:27,126,300...27,422,618
Ensembl chr16:27,126,286...27,422,268
JBrowse link
G GINS1 GINS complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:31,060,540...31,076,807
Ensembl chr17:31,060,631...31,081,629
JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17978847 NCBI chr  X:57,241,990...57,249,496
Ensembl chr  X:57,196,999...57,249,886
JBrowse link
G GJB2 gap junction protein beta 2 ISO DNA, mRNA:promoter hypermethylation, decreased expression:liver RGD PMID:17295234 RGD:2289638 NCBI chr11:774,090...781,252 JBrowse link
G GLI1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr 5:22,736,325...22,747,421
Ensembl chr 5:22,732,516...22,747,421
JBrowse link
G GLUL glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 9:123,751,551...123,762,575
Ensembl chr 9:123,751,548...123,762,547
JBrowse link
G GMNN geminin DNA replication inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:19,585,968...19,595,346
Ensembl chr 7:19,585,999...19,599,879
JBrowse link
G GMPS guanine monophosphate synthase ISO protein:increased activity:hepatoma (rat) RGD PMID:6861338 RGD:5135537 NCBI chr13:95,742,342...95,820,903
Ensembl chr13:95,742,383...95,819,762
JBrowse link
G GNAO1 G protein subunit alpha o1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:29,416,574...29,592,874
Ensembl chr 6:29,416,708...29,592,516
JBrowse link
G GNAS GNAS complex locus ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:1594625, PMID:1944469, PMID:2549426, PMID:3720010, PMID:7739708, PMID:8766942, PMID:9626141, PMID:12727968, PMID:12970318, PMID:15126527, PMID:16507630, PMID:21835143, PMID:23536913, PMID:24855271, PMID:25157968, PMID:26619011 NCBI chr17:58,985,580...59,053,022
Ensembl chr17:58,998,981...59,053,021
JBrowse link
G GNAZ G protein subunit alpha z ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:49,132,012...49,174,114
Ensembl chr14:49,132,013...49,174,109
JBrowse link
G GNMT glycine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19146867, PMID:31086990 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,218
JBrowse link
G GPC3 glypican 3 treatment
severity
ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
protein:increased expression:liver
CTD
RGD
PMID:16698587, PMID:19496787, PMID:25449037, PMID:28284560 RGD:14695019, RGD:14695020 NCBI chr  X:109,536,495...109,973,605
Ensembl chr  X:109,536,495...109,973,607
JBrowse link
G GPM6A glycoprotein M6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:38,258,496...38,555,129
Ensembl chr15:38,258,493...38,589,378
JBrowse link
G GPR158 G protein-coupled receptor 158 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:49,862,312...50,202,748
Ensembl chr10:49,862,312...50,202,453
JBrowse link
G GPR182 G protein-coupled receptor 182 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:22,303,466...22,309,652
Ensembl chr 5:22,304,588...22,311,031
JBrowse link
G GTSE1 G2 and S-phase expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:3,227,813...3,246,679
Ensembl chr 5:3,227,816...3,242,789
JBrowse link
G GYS2 glycogen synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:51,862,952...51,915,153
Ensembl chr 5:51,862,945...51,916,107
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO mRNA:decreased expression:liver (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:28284560, PMID:29235098 RGD:15042879 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,159...44,787,307
JBrowse link
G HAO2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:101,588,510...101,787,818
Ensembl chr 4:101,588,861...101,787,823
JBrowse link
G HDAC2 histone deacetylase 2 disease_progression ISO mRNA:increased expression:liver: RGD PMID:24448241 RGD:9590206 NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585
JBrowse link
G HDAC4 histone deacetylase 4 ISO mRNA:increased expression:liver: RGD PMID:21837748 RGD:9681451 NCBI chr15:138,378,237...138,657,266
Ensembl chr15:138,381,627...138,614,301
JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr 8:130,532,256...130,591,158
Ensembl chr 8:130,533,877...130,590,841
JBrowse link
G HFE homeostatic iron regulator disease_progression ISO associated with Liver Cirrhosis;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:20019189, PMID:29642405 RGD:14746967, RGD:2317357 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,768,741
JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9932610, PMID:11896611 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,437,087...98,513,156
JBrowse link
G HGFAC HGF activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 8:2,077,164...2,084,506
Ensembl chr 8:2,077,176...2,084,507
JBrowse link
G HHIP hedgehog interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18559595 NCBI chr 8:83,583,735...83,678,368
Ensembl chr 8:83,583,737...83,679,136
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha disease_progression
treatment
ISO protein:increased expression:liver (human) RGD PMID:19335982, PMID:26078356 RGD:11526468, RGD:9068886 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HJURP Holliday junction recognition protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:134,106,561...134,123,163
Ensembl chr15:134,106,569...134,123,107
JBrowse link
G HMGB2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20851854 NCBI chr14:16,709,966...16,712,288
Ensembl chr14:16,710,047...16,717,126
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9207284, PMID:21147110 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,225...84,402,956
JBrowse link
G HMMR hyaluronan mediated motility receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:60,290,684...60,332,411
Ensembl chr16:60,290,000...60,332,371
JBrowse link
G HNF1A HNF1 homeobox A treatment ISO human cell line in mouse model RGD PMID:29466992 RGD:14700664 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO protein:decreased expression:liver: RGD PMID:20876809 RGD:12904747 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,503
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr 5:19,485,033...19,491,418
Ensembl chr 5:19,485,096...19,491,419
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO mRNA:increased expression:liver (rat)
protein:increased expression:liver (human)
RGD PMID:20604928, PMID:23633480 RGD:9685422, RGD:9685423 NCBI chr18:46,205,164...46,215,861
Ensembl chr18:46,205,418...46,215,858
JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B severity ISO mRNA:increased expression:liver (human) RGD PMID:24638979 RGD:10059322 NCBI chr 2:80,186,998...80,194,155 JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D ISO protein:increased expression:liver (human)
protein:increased expression:liver (rat)
RGD PMID:20102719, PMID:22318685 RGD:10042969, RGD:10042977 NCBI chr 8:135,844,492...135,862,633
Ensembl chr 8:135,844,487...135,862,633
JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 ISO protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr 2:78,961,456...78,971,799
Ensembl chr 2:78,961,556...78,974,362
JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L ISO associated with Hepatitis B RGD PMID:24125732 RGD:9999429 NCBI chr 6:47,643,561...47,655,856
Ensembl chr 6:47,530,238...47,655,557
JBrowse link
G HOXA10 homeobox A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,712...45,403,257
JBrowse link
G HOXA13 homeobox A13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:45,373,340...45,379,046
Ensembl chr18:45,373,440...45,380,300
JBrowse link
G HOXD9 homeobox D9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:81,910,415...81,926,276
Ensembl chr15:81,924,142...81,926,274
JBrowse link
G HP haptoglobin ISO protein:increased expression:saliva RGD PMID:31041878 RGD:27095881 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr  X:110,321,144...110,357,902
Ensembl chr  X:110,321,208...110,357,899
JBrowse link
G HRAS HRas proto-oncogene, GTPase treatment ISO human cells in a mouse model
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: LIVER CELL CARCINOMA
human plasmid in a mouse model
mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
RGD
ClinVar
CTD
PMID:2219132, PMID:8200073, PMID:9311599, PMID:10791191, PMID:11150980, PMID:12210337, PMID:12835555, PMID:14608654, PMID:15806265, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17211612, PMID:17250658, PMID:17384584, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18042262, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19213030, PMID:19255327, PMID:19371735, PMID:19382114, PMID:19669404, PMID:19773371, PMID:20118494, PMID:20660566, PMID:20859122, PMID:20979192, PMID:21438134, PMID:21495179, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22256804, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22726224, PMID:22926243, PMID:23093928, PMID:23096712, PMID:23406027, PMID:23429430, PMID:23555816, PMID:23751039, PMID:23884457, PMID:24006476, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:24390138, PMID:25157968, PMID:25326635, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27517622, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28284560, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759, PMID:168335863 RGD:14688054, RGD:14688055, RGD:14694809, RGD:14694810 NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284, PMID:29698666 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:140,515,239...140,532,164
Ensembl chr 2:140,515,246...140,531,845
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 3:10,038,074...10,039,441
Ensembl chr 3:10,037,936...10,039,915
JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16799960 NCBI chr 2:39,035,337...39,052,178
Ensembl chr 2:39,034,013...39,189,152
JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:26109813 RGD:11056752 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: LIVER CELL CARCINOMA
CTD
ClinVar
PMID:18772396, PMID:19657110, PMID:19798509, PMID:19818334, PMID:20946881, PMID:21352804, PMID:21446021, PMID:21472284, PMID:22160010, PMID:22397365, PMID:22417203, PMID:22898539, PMID:23558169, PMID:24606448, PMID:25043048, PMID:25157968, PMID:25741868, PMID:26619011 NCBI chr15:111,341,153...111,362,330
Ensembl chr15:111,341,152...111,362,280
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO ClinVar Annotator: match by term: Hepatocellular carcinoma RGD
ClinVar
PMID:20946881, PMID:21250968, PMID:21596855, PMID:21997850, PMID:22160010, PMID:22397365, PMID:22417203, PMID:22616558, PMID:22898539, PMID:23949315, PMID:24606448, PMID:24716838, PMID:25157968, PMID:26619011 RGD:14985249 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,606...55,681,426
JBrowse link
G IFNA1 interferon, alpha 1 susceptibility ISO CTD Direct Evidence: therapeutic
associated with hepatitis B; DNA:SNP:: ( rs1831583) (human)
CTD
RGD
PMID:17088986, PMID:17971768, PMID:18665156, PMID:29080269 RGD:21406429 NCBI chr 1:201,515,835...201,516,477
Ensembl chr 1:201,736,694...201,750,298
JBrowse link
G IGBP1 immunoglobulin binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21339737 NCBI chr  X:56,173,773...56,206,121 JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IGF1R insulin like growth factor 1 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs, haplotype: :
CTD
RGD
PMID:17441810, PMID:23958494, PMID:24758241 RGD:14985227 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,925...137,690,666
JBrowse link
G IGF2 insulin like growth factor 2 susceptibility ISO associated with hepatitis B;DNA:SNPs:intron, 3'utr:+2482A>C, +820A>G (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12532445, PMID:16092956, PMID:16750516, PMID:17554210 RGD:14401723, RGD:2311523 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:25,196,955...25,244,660
Ensembl chr12:25,196,969...25,243,272
JBrowse link
G IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:92,104,786...92,272,264
Ensembl chr 9:92,104,847...92,272,211
JBrowse link
G IGF2R insulin like growth factor 2 receptor disease_progression
no_association
treatment
ISO DNA:loss of heterozygosity:liver
DNA:loss of heterozygosity,mutations:liver:
OMIM
RGD
PMID:10347113, PMID:18322954, PMID:30720132 RGD:14985219, RGD:14985220, RGD:14985221 NCBI chr 1:7,369,485...7,472,480
Ensembl chr 1:7,368,103...7,472,548
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:40,173,595...40,177,789
Ensembl chr 3:40,174,764...40,177,785
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23822114, PMID:26890368 RGD:14975171, RGD:7365006 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL12A interleukin 12A susceptibility ISO associated with hepatitis B; DNA:SNP, haplotype:3′UTR :rs568408(human)
DNA:SNP:3'UTR: rs568408( G>A)(human)
associated with hepatitis C;DNA:SNP:3'UTR: rs568408( G>A)(human)
RGD PMID:20521253, PMID:26631030, PMID:27819525 RGD:25440490, RGD:25440491, RGD:25440501 NCBI chr13:99,733,394...99,741,078
Ensembl chr13:99,733,394...99,741,078
JBrowse link
G IL18 interleukin 18 disease_progression
susceptibility
severity
ISO associated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human)
DNA:SNP:promoter:-137G>C(rs187238)(human)
associated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human)
RGD PMID:26893476, PMID:27429592, PMID:27470888, PMID:29341496 RGD:11538094, RGD:14695526, RGD:14695540, RGD:14696663 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,966...39,873,300
JBrowse link
G IL1RAP interleukin 1 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:127,933,239...128,071,984
Ensembl chr13:127,933,682...128,072,348
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560
G IL2 interleukin 2 treatment ISO RGD PMID:9449371, PMID:10933975 RGD:14747035, RGD:8693323 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL6 interleukin 6 treatment ISO DNA:SNP: :rs2069852 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17615358, PMID:20818158, PMID:26297436, PMID:27022031, PMID:27368337 RGD:14975289 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G IL6ST interleukin 6 signal transducer ISO RGD PMID:15780071 RGD:1626706 NCBI chr16:35,101,304...35,151,832
Ensembl chr16:35,101,304...35,211,982
JBrowse link
G ING3 inhibitor of growth family member 3 treatment ISO RGD PMID:25156538 RGD:9587823 NCBI chr18:25,946,529...25,976,528
Ensembl chr18:25,948,087...25,976,499
JBrowse link
G INMT indolethylamine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:42,213,335...42,218,175
Ensembl chr18:42,209,402...42,218,174
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 8:84,812,041...85,555,200
Ensembl chr 8:84,811,772...85,514,518
JBrowse link
G INSR insulin receptor ISO human cells in a mouse model
mRNA, protein:increased expression:liver (human, rat)
RGD PMID:23633480, PMID:29610518 RGD:14700930, RGD:9685423 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,139
JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20977743 NCBI chr 7:53,020,479...53,129,964
Ensembl chr 7:52,958,106...53,129,960
JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20977743 NCBI chr 2:85,294,423...85,633,645
Ensembl chr 2:85,294,434...85,636,317
JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:93,495,999...93,556,915
Ensembl chr 4:93,513,079...93,559,020
JBrowse link
G IRF2 interferon regulatory factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr15:45,546,779...45,693,241
Ensembl chr15:45,546,779...45,656,928
JBrowse link
G IRS1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1311924, PMID:23958494 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,308,335
JBrowse link
G IRS2 insulin receptor substrate 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16127164 NCBI chr11:76,626,158...76,654,639
Ensembl chr11:76,626,179...76,653,881
JBrowse link
G ISG15 ISG15 ubiquitin like modifier ISO CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr 6:63,363,201...63,364,211
Ensembl chr 6:63,363,173...63,364,208
JBrowse link
G ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr13:34,911,104...34,924,881
Ensembl chr13:34,892,369...34,937,568
JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO protein:increased expression:liver RGD PMID:30660174 RGD:14694832 NCBI chr17:19,591,248...19,629,659
Ensembl chr17:19,591,252...19,630,085
JBrowse link
G JAK1 Janus kinase 1 treatment ISO RGD PMID:26701727 RGD:11574921 NCBI chr 6:147,320,288...147,567,188
Ensembl chr 6:147,429,106...147,567,179
JBrowse link
G JAK2 Janus kinase 2 severity ISO mRNA:decreased expression:liver (human) RGD PMID:25420511 RGD:18182928 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,686...217,002,148
JBrowse link
G JDP2 Jun dimerization protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr 7:98,574,386...98,616,480
Ensembl chr 7:98,574,198...98,616,474
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr 6:153,686,425...153,687,635 JBrowse link
G KAT2B lysine acetyltransferase 2B severity ISO protein:decreased expression:liver (human) RGD PMID:23643089 RGD:9590314 NCBI chr13:6,985,151...7,099,771
Ensembl chr13:6,985,235...7,100,346
JBrowse link
G KBTBD11 kelch repeat and BTB domain containing 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:33,487,439...33,501,274
Ensembl chr15:33,494,430...33,497,201
JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 ISO protein:increased expression:liver (human) RGD PMID:17022810 RGD:9693723 NCBI chr 9:131,960,566...132,336,029 JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:118,439,328...118,882,299
Ensembl chr 2:118,439,403...118,882,296
JBrowse link
G KDM1A lysine demethylase 1A severity ISO mRNA, protein:increased expression:liver (human) RGD PMID:23236241 RGD:9681002 NCBI chr 6:80,903,407...80,971,875
Ensembl chr 6:80,903,496...80,971,595
JBrowse link
G KDM3A lysine demethylase 3A ISO mRNA:increased expression:liver (human) RGD PMID:21607773 RGD:9590222 NCBI chr 3:58,300,109...58,355,000
Ensembl chr 3:58,299,706...58,354,941
JBrowse link
G KDM8 lysine demethylase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:19,653,396...19,676,207
Ensembl chr 3:19,650,615...19,676,148
JBrowse link
G KIF11 kinesin family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:104,125,839...104,177,381
Ensembl chr14:104,125,898...104,177,379
JBrowse link
G KIF14 kinesin family member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:23,123,379...23,177,919
Ensembl chr10:23,125,239...23,174,273
JBrowse link
G KIF15 kinesin family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:27,966,586...28,041,121
Ensembl chr13:27,966,586...28,041,473
JBrowse link
G KIF18A kinesin family member 18A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:32,244,073...32,331,392
Ensembl chr 2:32,244,137...32,335,736
JBrowse link
G KIF18B kinesin family member 18B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:18,426,828...18,448,214
Ensembl chr12:18,426,835...18,448,213
JBrowse link
G KIF1B kinesin family member 1B severity
susceptibility
ISO mRNA, protein:decreased expression:liver (human)
DNA:snp:intron:c.2537+518A>G (rs17401966) (human)
RGD PMID:26217094, PMID:27122668 RGD:11052488, RGD:12738461 NCBI chr 6:70,495,143...70,663,464
Ensembl chr 6:70,495,144...70,663,463
JBrowse link
G KIF20A kinesin family member 20A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:140,202,316...140,213,144
Ensembl chr 2:140,202,015...140,211,157
JBrowse link
G KIF23 kinesin family member 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:167,239,973...167,281,250
Ensembl chr 1:167,240,013...167,282,158
JBrowse link
G KIF2C kinesin family member 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:166,556,765...166,577,904
Ensembl chr 6:166,556,774...166,577,904
JBrowse link
G KIF4A kinesin family member 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:56,319,453...56,447,560
Ensembl chr  X:56,296,984...56,448,230
JBrowse link
G KIFC1 kinesin family member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:29,692,775...29,713,716
Ensembl chr 7:29,694,788...29,713,690
JBrowse link
G KLF4 Kruppel like factor 4 treatment
disease_progression
ISO RGD PMID:22677193 RGD:14402023 NCBI chr 1:248,604,817...248,609,574
Ensembl chr 1:248,604,820...248,609,574
JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 9:45,743,566...45,828,559 JBrowse link
G KMT2B lysine methyltransferase 2B ISO DNA:insertions, translocations:intron:IVS3, multiple (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18320596, PMID:22634754 RGD:9588597 NCBI chr 6:45,146,863...45,166,854
Ensembl chr 6:45,146,846...45,166,852
JBrowse link
G KMT2C lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr18:4,993,213...5,279,668
Ensembl chr18:4,993,196...5,279,042
JBrowse link
G KRAS KRAS proto-oncogene, GTPase induced ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: LIVER CELL CARCINOMA
aflatoxin B1 induced:DNA:transversion,transition mutations:cds:
mRNA,protein:increased expression:liver
CTD
ClinVar
RGD
PMID:2278970, PMID:3122217, PMID:8446626, PMID:11286481, PMID:11563603, PMID:12460918, PMID:15696205, PMID:16361624, PMID:16434492, PMID:16618717, PMID:18316791, PMID:18794081, PMID:19075190, PMID:19114683, PMID:19679400, PMID:20921462, PMID:20921465, PMID:21228335, PMID:22407852, PMID:22722830, PMID:23325582, PMID:25157968, PMID:26619011, PMID:29275358 RGD:11568697, RGD:14398750 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,790...48,549,346
JBrowse link
G LCAT lecithin-cholesterol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:28,550,356...28,553,561
Ensembl chr 6:28,550,357...28,553,567
JBrowse link
G LEP leptin severity
susceptibility
ISO protein:increased expression:liver (human)
DNA:SNP:enhancer:-2548G>A (rs7799039) (human)
RGD PMID:18573568, PMID:28452232 RGD:15039399, RGD:25330348 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,447
JBrowse link
G LEPR leptin receptor susceptibility ISO associated with Hepatitis B, Chronic;DNA:SNPs:cds:p.Gln223Arg, Lys109Arg (human) RGD PMID:23090836 RGD:21079466 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,798,979...146,896,108
JBrowse link
G LETM1 leucine zipper and EF-hand containing transmembrane protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23392203 NCBI chr 8:898,178...926,500
Ensembl chr 8:898,178...926,607
JBrowse link
G LOC100157117 kallistatin ISO CTD Direct Evidence: therapeutic CTD PMID:19709125 NCBI chr 7:115,781,772...115,792,469
Ensembl chr 7:115,783,931...115,792,466
JBrowse link
G LOC100513779 solute carrier family 22 member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560, PMID:30705370 NCBI chr 2:8,580,673...8,603,553 JBrowse link
G LOC100515114 serine/threonine-protein phosphatase 4 regulatory subunit 3B-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:23,301,323...23,303,743 JBrowse link
G LOC100517408 cytochrome c oxidase subunit 7B2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:36,736,233...36,856,176 JBrowse link
G LOC100522011 apoptosis-associated speck-like protein containing a CARD ISO CTD Direct Evidence: marker/mechanism CTD PMID:17471463 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,179...17,307,512
JBrowse link
G LOC100739163 glutathione S-transferase P-like ISO DNA:increased methylation:promoter
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9029167, PMID:22536438 RGD:14401712 NCBI chr 2:4,978,761...4,982,233 JBrowse link
G LOC102167255 leukemia inhibitory factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:23,627,700...23,672,724
Ensembl chr16:23,631,195...24,042,240
JBrowse link
G LOC110258578 interleukin-1 beta-like susceptibility ISO DNA:polymorphism:promoter:-31T>C (human) RGD PMID:21653279 RGD:7401222
G LOC110260333 hydroxymethylglutaryl-CoA synthase, mitochondrial-like disease_progression ISO RGD PMID:28867541 RGD:14975299 NCBI chr 4:101,385,486...101,404,273
Ensembl chr 4:101,385,512...101,443,405
JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 ISO RGD PMID:19000703 RGD:2317680 NCBI chr 1:251,811,583...251,979,828
Ensembl chr 1:251,811,584...251,979,159
JBrowse link
G LRAT lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:74,412,226...74,428,713
Ensembl chr 8:74,409,459...74,419,682
JBrowse link
G LRRC1 leucine rich repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:26,860,138...26,989,664
Ensembl chr 7:26,860,140...26,990,017
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar PMID:11150980, PMID:12210337, PMID:12835555, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17211612, PMID:17250658, PMID:17384584, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18042262, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19213030, PMID:19255327, PMID:19371735, PMID:19382114, PMID:19669404, PMID:19773371, PMID:20660566, PMID:20859122, PMID:20979192, PMID:21438134, PMID:21495179, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22256804, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22726224, PMID:22926243, PMID:23093928, PMID:23096712, PMID:23406027, PMID:23429430, PMID:23751039, PMID:23884457, PMID:24006476, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:24390138, PMID:25157968, PMID:25326635, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759, PMID:168335863 NCBI chr 2:303,836...323,701
Ensembl chr 2:304,429...323,700
JBrowse link
G LRRC59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr12:26,678,207...26,694,277
Ensembl chr12:26,675,054...26,694,271
JBrowse link
G LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:48,937,357...48,954,206
Ensembl chr 2:48,937,417...48,954,203
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:103,927,358...103,936,669
Ensembl chr 8:103,927,353...103,936,664
JBrowse link
G MAPT microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:17,098,259...17,211,483
Ensembl chr12:17,095,587...17,211,368
JBrowse link
G MARCO macrophage receptor with collagenous structure ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:24,502,935...24,541,286
Ensembl chr15:24,503,108...24,541,353
JBrowse link
G MAT1A methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12060674 NCBI chr14:82,109,405...82,126,487
Ensembl chr14:82,109,404...82,127,049
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility
no_association
severity
ISO DNA:SNPs:promoter:rs7096206(human)
associated with hepatitis B;DNA:SNP:exon:
associated with hepatitis B-related cirrhosis;DNA:SNP: :rs11003123(G>A)(human)
associated with viral hepatitis;DNA:polymorphisms:exon:
associated with hepatitis C;DNA:SNP: :221C>G(rs709620)(human)
protein:decreased expression:plasma
RGD PMID:18221301, PMID:21733090, PMID:25787238, PMID:26857650, PMID:27298104, PMID:27557564 RGD:14696813, RGD:14696814, RGD:14696829, RGD:14696833, RGD:14696835, RGD:14696836 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,894...97,108,936
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 6:4,503,530...4,558,601
Ensembl chr 6:4,503,573...4,558,609
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr  X:18,013,360...18,054,250 JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:48,481,292...48,523,921
Ensembl chr10:48,480,700...48,582,857
JBrowse link
G MCM2 minichromosome maintenance complex component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:72,630,378...72,651,270
Ensembl chr13:72,630,380...72,657,620
JBrowse link
G MCM7 minichromosome maintenance complex component 7 susceptibility ISO associated with hepatitis B;DNA:SNP:promoter: (rs999885) (human)
associated with hepatitis B;miRNA:increased expression:liver (human)
RGD PMID:24416400, PMID:27298561 RGD:15042853, RGD:15042885 NCBI chr 3:8,005,890...8,014,047
Ensembl chr 3:8,005,900...8,014,053
JBrowse link
G MDM2 MDM2 proto-oncogene susceptibility ISO DNA:transversion:promoter:g.-309T>G (human) RGD PMID:20019189 RGD:2317357 NCBI chr 5:33,105,717...33,137,602
Ensembl chr 5:33,086,994...33,178,089
JBrowse link
G ME1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 1:82,799,878...82,989,895
Ensembl chr 1:82,794,964...82,991,104
JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver
CTD
RGD
PMID:11844796, PMID:26189965 RGD:2289670 NCBI chr  X:124,735,523...124,789,063
Ensembl chr  X:124,735,656...124,789,110
JBrowse link
G MED1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20007298 NCBI chr12:22,830,405...22,872,420
Ensembl chr12:22,839,005...22,872,407
JBrowse link
G MELK maternal embryonic leucine zipper kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:237,317,161...237,431,522
Ensembl chr 1:237,317,170...237,440,387
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO OMIM NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,044...29,541,512
JBrowse link
G MFSD2A major facilitator superfamily domain containing 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:95,738,961...95,753,245
Ensembl chr 6:95,738,973...95,814,953
JBrowse link
G MIR107 microRNA mir-107 onset
treatment
ISO RNA:increased expression:liver:
RNA:decreased expression:liver:
RGD PMID:26191213, PMID:27773820, PMID:28079796, PMID:30738047 RGD:11066920, RGD:14975277, RGD:14975278, RGD:14975300 NCBI chr14:101,420,743...101,420,829
Ensembl chr14:101,420,743...101,420,829
JBrowse link
G MIR122 microRNA mir-122 severity ISO CTD Direct Evidence: marker/mechanism
associated with hepatitis B; miRNA:decreased expression:liver
CTD
RGD
PMID:16924677, PMID:25269820, PMID:25422324 RGD:14394424, RGD:14401603 NCBI chr 1:162,329,776...162,329,860
Ensembl chr 1:162,329,767...162,329,860
JBrowse link
G MIR125A microRNA mir-125a treatment
severity
ISO RNA:increased expression:liver: RGD PMID:29951066, PMID:30257386 RGD:21403677, RGD:21403679 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
JBrowse link
G MIR145 microRNA mir-145 severity ISO miRNA:decreased expression:liver (human) RGD PMID:30572504 RGD:15039395 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211
JBrowse link
G MIR152 microRNA mir-152 disease_progression ISO miRNA:decreased expression:liver RGD PMID:26531720, PMID:30967300 RGD:19165146, RGD:21066331 NCBI chr12:24,292,249...24,292,328
Ensembl chr12:24,292,251...24,292,336
JBrowse link
G MIR155 microRNA mir-155 disease_progression ISO miRNA:increased expression:serum
miRNA:decreased expression:peripheral blood mononuclear cell
associated with hepatitis C;DNA:SNP: :rs767649 (human)
RGD PMID:27035278, PMID:27531892, PMID:28074870, PMID:29528577, PMID:30710754 RGD:21079433, RGD:21079477, RGD:21081523, RGD:24922222, RGD:25671465 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G MIR181C microRNA mir-181c ISO miRNA:decreased expression:liver (human) RGD PMID:31114379 RGD:15042894 NCBI chr 2:65,279,950...65,280,036
Ensembl chr 2:65,279,944...65,280,040
JBrowse link
G MIR18A microRNA mir-18a severity ISO associated with Hepatitis C, Chronic;miRNA:increased expression:serum (human)
associated with hepatitis B;miRNA:increased expression:liver (human)
RGD PMID:19027010, PMID:24975878, PMID:29455432, PMID:30191950, PMID:30519035 RGD:15039389, RGD:15039398, RGD:15039400, RGD:15039401, RGD:15039404 NCBI chr11:60,734,791...60,734,882
Ensembl chr11:60,734,791...60,734,882
JBrowse link
G MIR195 microRNA mir-195 severity ISO miRNA:decreased expression:liver (mouse)
miRNA:decreased expression:liver (human)
RGD PMID:25607636 RGD:15042896 NCBI chr12:52,422,039...52,422,118
Ensembl chr12:52,422,039...52,422,118
JBrowse link
G MIR196A-2 microRNA mir-196a-2 susceptibility ISO associated with hepatitis B, chronic; DNA:SNP: : (rs12304647)
DNA:SNP: : (rs11614913)
RGD PMID:21692953, PMID:24248733 RGD:14401594, RGD:14401595 NCBI chr 5:19,204,442...19,204,548
Ensembl chr 5:19,204,442...19,204,548
JBrowse link
G MIR199B microRNA mir-199b disease_progression ISO miRNA:decreased expression:liver RGD PMID:30536310 RGD:14694833 NCBI chr 1:268,691,520...268,691,593
Ensembl chr 1:268,691,502...268,691,610
JBrowse link
G MIR20A microRNA mir-20a ISO associated with Human Viral Hepatitis RGD PMID:30623908 RGD:25823145 NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196
JBrowse link
G MIR21 microRNA mir-21 ISO miRNA:increased expression:liver RGD PMID:20447717 RGD:14695022 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G MIR221 microRNA mir-221 treatment
disease_progression
ISO RGD PMID:22009537, PMID:25817558, PMID:28096271, PMID:29713162 RGD:11086123, RGD:18337267, RGD:18337273, RGD:18337275 NCBI chr  X:40,571,068...40,571,137
Ensembl chr  X:40,571,068...40,571,137
JBrowse link
G MIR224 microRNA mir-224 severity ISO associated with hepatitis B;miRNA:increased expression:liver (human)
miRNA:increased expression:plasma (human)
RGD PMID:22459148, PMID:23913306, PMID:23922662, PMID:24923856, PMID:27462777 RGD:18182921, RGD:18182922, RGD:18182923, RGD:18182924, RGD:18182926 NCBI chr  X:123,283,427...123,283,507
Ensembl chr  X:123,283,427...123,283,507
JBrowse link
G MIR23A microRNA mir-23a ISO miRNA:increased expression:liver RGD PMID:22318941 RGD:14694846 NCBI chr 2:65,308,117...65,308,186
Ensembl chr 2:65,308,117...65,308,186
JBrowse link
G MIR29A microRNA mir-29a severity ISO associated with hepatitis B;miRNA:increased expression:liver (human) RGD PMID:23285022 RGD:15042850 NCBI chr18:18,040,032...18,040,117
Ensembl chr18:18,040,032...18,040,118
JBrowse link
G MIR885 microRNA mir-885 ISO CTD Direct Evidence: therapeutic CTD PMID:27738331 NCBI chr13:66,597,531...66,597,610
Ensembl chr13:66,597,531...66,597,610
JBrowse link
G MIR96 microRNA mir-96 severity ISO miRNA:increased expression:liver (human) RGD PMID:25813403, PMID:28892647 RGD:15042901, RGD:15042902 NCBI chr18:18,982,506...18,982,590
Ensembl chr18:18,982,506...18,982,590
JBrowse link
G MIRLET7C microRNA let-7c ISO miRNA:decreased expression:liver RGD PMID:22289550 RGD:14695021 NCBI chr13:181,303,209...181,303,302
Ensembl chr13:181,303,209...181,303,302
JBrowse link
G MKI67 marker of proliferation Ki-67 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:137,266,622...137,296,312 JBrowse link
G MLXIPL MLX interacting protein like ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 3:10,898,675...10,934,257
Ensembl chr 3:10,894,270...10,934,047
JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:8302012 RGD:13801035 NCBI chr13:95,018,395...95,122,977
Ensembl chr13:95,019,081...95,126,045
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20084675 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,594...30,086,982
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20084675, PMID:21681821 RGD:8547864 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,175,056...48,188,264
JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:9,937,654...9,951,679
Ensembl chr 9:9,937,700...10,008,913
JBrowse link
G MPO myeloperoxidase susceptibility
disease_progression
ISO CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis; DNA:SNP:promoter:-463G>A( rs2333227)(human)
associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-463G>A(human)
CTD
RGD
PMID:19731237, PMID:21907168 RGD:26923907, RGD:27095879 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904
JBrowse link
G MRO maestro ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:100,342,040...100,368,355
Ensembl chr 1:100,340,048...100,512,463
JBrowse link
G MSH5 mutS homolog 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:23,852,864...23,872,760 JBrowse link
G MT-2B metallothionein-2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17363595, PMID:28284560 NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,059...18,646,033
JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I ISO RGD PMID:2548155 RGD:2302301 NCBI chr MT:6,511...8,055
Ensembl chr MT:6,511...8,055
JBrowse link
G MT-ND5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 ISO mRNA:increased expression:liver RGD PMID:2507335 RGD:2302316 NCBI chr MT:12,935...14,755
Ensembl chr MT:12,935...14,755
JBrowse link
G MT1A metallothionein 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17363595, PMID:19363144 NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,660,642...18,673,766
JBrowse link
G MTBP MDM2 binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29765550 NCBI chr 4:18,533,201...18,608,702
Ensembl chr 4:18,532,002...18,608,604
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase ISO mRNA:increased expression:liver RGD PMID:3878730 RGD:2302305 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,819,612...68,853,067
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
disease_progression
onset
ISO DNA:SNP,haplotype: :677C>T, 1298A>C(human)
DNA:SNP: :677C>T(human)
DNA:SNPs: :677C>T, 1298A>C(human)
DNA:SNP: :1298A>C(human)
RGD PMID:17503006, PMID:17659576, PMID:19035314, PMID:23996892 RGD:14696703, RGD:14696704, RGD:14696707, RGD:14696708 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:SNP: :66A>G(human) RGD PMID:19035314 RGD:14696707 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,224...74,270,802
JBrowse link
G MVK mevalonate kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr14:41,320,790...41,357,437
Ensembl chr14:41,281,671...41,362,974
JBrowse link
G MYBL2 MYB proto-oncogene like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:46,256,245...46,287,929
Ensembl chr17:46,256,257...46,287,929
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment
severity
ISO mRNA:increased expression:liver (rat)
mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9029167, PMID:12029619, PMID:15565109, PMID:21644509, PMID:22076107, PMID:22129741, PMID:22434528, PMID:29698666 RGD:6903288, RGD:7240567, RGD:7240695, RGD:7241004 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,119...12,461,078
JBrowse link
G MYDGF myeloid derived growth factor ISO protein:increased expression:serum (human) RGD PMID:19081304 RGD:39128258 NCBI chr 2:74,185,042...74,202,306
Ensembl chr 2:74,185,037...74,202,301
JBrowse link
G NCAPG non-SMC condensin I complex subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:12,759,225...12,807,164
Ensembl chr 8:12,759,639...12,810,050
JBrowse link
G NCAPH non-SMC condensin I complex subunit H ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:46,852,388...46,893,008
Ensembl chr 3:46,852,392...46,899,186
JBrowse link
G NDC80 NDC80 kinetochore complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:104,000,794...104,055,785
Ensembl chr 6:103,998,698...104,055,762
JBrowse link
G NEIL3 nei like DNA glycosylase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:39,416,073...39,632,313
Ensembl chr15:39,581,856...39,632,310
JBrowse link
G NEK2 NIMA related kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:131,547,044...131,560,527
Ensembl chr 9:131,547,084...131,560,527
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular carcinoma
CTD
ClinVar
RGD
PMID:22561517, PMID:26619011, PMID:29018201, PMID:31546024 RGD:21201310 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G NFKBIA NFKB inhibitor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:22022477 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G NKX3-1 NK3 homeobox 1 treatment ISO mRNA:decreased expression:liver
human gene in a mouse model
RGD PMID:28972178 RGD:14401599 NCBI chr14:7,783,296...7,787,036
Ensembl chr14:7,782,421...7,787,034
JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30081150 NCBI chr 3:38,673,590...38,719,188
Ensembl chr 3:38,673,622...38,717,451
JBrowse link
G NLRC5 NLR family CARD domain containing 5 ISO protein:increased expression:liver RGD PMID:27338800 RGD:15003194 NCBI chr 6:18,933,179...19,036,288
Ensembl chr 6:18,937,665...19,036,820
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr12:27,416,308...27,435,044
Ensembl chr12:27,416,337...27,436,160
JBrowse link
G NNMT nicotinamide N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:41,871,072...41,882,415
Ensembl chr 9:41,870,980...41,882,760
JBrowse link
G NOTCH3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:62,364,507...62,402,348
Ensembl chr 2:62,364,501...62,402,344
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23811326 NCBI chr 6:84,225,670...84,228,156
Ensembl chr 6:84,225,694...84,228,094
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 6:55,238,536...55,245,457
Ensembl chr 6:55,237,953...55,245,456
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: marker/mechanism
intestinally expressed human gene in mouse model
mRNA:splice variant(s):liver (human)
RGD
CTD
PMID:23213087, PMID:23811326, PMID:24954587, PMID:25496033 RGD:14696796, RGD:14928330, RGD:14928334 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,288...83,684,604
JBrowse link
G NRAS NRAS proto-oncogene, GTPase severity
disease_progression
ISO mRNA, protein:increased expression:liver (mouse, human)
ClinVar Annotator: match by term: LIVER CELL CARCINOMA
human gene in mouse model
RGD
ClinVar
PMID:1654209, PMID:2278970, PMID:2674680, PMID:3122217, PMID:6587382, PMID:8120410, PMID:10821536, PMID:12460918, PMID:12727991, PMID:14508525, PMID:15899789, PMID:16273091, PMID:16291983, PMID:16434492, PMID:17699718, PMID:18390968, PMID:18633438, PMID:18668139, PMID:18948947, PMID:19075190, PMID:19657110, PMID:19880792, PMID:20130576, PMID:20149136, PMID:20179705, PMID:20406486, PMID:20619739, PMID:20736745, PMID:21107323, PMID:21305640, PMID:21576590, PMID:21729679, PMID:21829508, PMID:21993994, PMID:22407852, PMID:22499344, PMID:22718121, PMID:22761467, PMID:22773810, PMID:23076151, PMID:23392294, PMID:23400451, PMID:23414587, PMID:23515407, PMID:23538902, PMID:23569304, PMID:23614898, PMID:24006476, PMID:24033266, PMID:24148783, PMID:24370118, PMID:24671188, PMID:25157968, PMID:25348872, PMID:25695684, PMID:26619011, PMID:26821351, PMID:27050078, PMID:28492532, PMID:28780248, PMID:30685691 RGD:14696775, RGD:14696793 NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227
JBrowse link
G NRG1 neuregulin 1 disease_progression ISO mRNA:increased expression:liver (human)
associated with hepatitis C;mRNA:altered expression:liver (human
RGD PMID:17393520, PMID:27514687 RGD:39456104, RGD:39456110 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,627,334...53,688,332
JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex treatment
disease_progression
ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:28284560, PMID:30653265, PMID:31933938 RGD:28867240, RGD:28912742 NCBI chr 4:87,162,873...87,194,193
Ensembl chr 4:87,162,817...87,194,170
JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:129,992,797...130,065,641 JBrowse link
G OIT3 oncoprotein induced transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:75,726,353...75,753,461
Ensembl chr14:75,726,364...75,754,343
JBrowse link
G OLFML2A olfactomedin like 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:265,577,250...265,604,365
Ensembl chr 1:265,577,114...265,604,502
JBrowse link
G OLFML2B olfactomedin like 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:88,522,171...88,560,305
Ensembl chr 4:88,521,893...88,560,382
JBrowse link
G ORC1 origin recognition complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:159,819,302...159,852,306
Ensembl chr 6:159,819,358...159,853,802
JBrowse link
G P14ARF p14ARF protein severity ISO Protein:increased expression:liver
ClinVar Annotator: match by term: LIVER CELL CARCINOMA
DNA:hypermethylation:exon
CTD Direct Evidence: marker/mechanism
DNA:hypermethylation:promoter
Protein:decreased expression:liver
RGD
ClinVar
CTD
PMID:7780957, PMID:8521414, PMID:9324288, PMID:10491434, PMID:11301474, PMID:12359353, PMID:16234564, PMID:16317707, PMID:16896043, PMID:21462282, PMID:25157968, PMID:25822088, PMID:26619011, PMID:28284560, PMID:28492532 RGD:1600816, RGD:1600822, RGD:8552680 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,774,496...200,798,854
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 disease_progression ISO mRNA,protein:decreased expression:liver: RGD PMID:21569763 RGD:12790589 NCBI chr12:48,567,329...48,735,836
Ensembl chr12:48,567,337...48,735,838
JBrowse link
G PAMR1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:25,422,390...25,591,615
Ensembl chr 2:25,423,361...25,591,617
JBrowse link
G PARK7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,520
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18695907 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,159...14,241,197
JBrowse link
G PBK PDZ binding kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:11,543,657...11,577,286
Ensembl chr14:11,543,599...11,566,702
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144, PMID:28284560 NCBI chr17:57,930,507...57,936,523
Ensembl chr17:57,930,432...57,938,896
JBrowse link
G PCLAF PCNA clamp associated factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:107,659,509...107,669,477
Ensembl chr 1:107,659,501...107,670,978
JBrowse link
G PCNA proliferating cell nuclear antigen treatment ISO protein:increased expression:liver: RGD PMID:23219601 RGD:10448993 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,125,814...14,185,276
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20506153 Ensembl chr 5:8,986,461...9,007,446 JBrowse link
G PDGFRL platelet derived growth factor receptor like ISO OMIM NCBI chr17:5,278,872...5,328,859
Ensembl chr17:5,279,004...5,329,511
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28003426 NCBI chr 9:75,246,956...75,260,134
Ensembl chr 9:75,246,002...75,260,134
JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase ISO protein:increased activity:hepatoma (rat) RGD PMID:6722784 RGD:5135276 NCBI chr12:53,458,401...53,477,254 JBrowse link
G PGD phosphogluconate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 6:70,675,751...70,692,697
Ensembl chr 6:70,675,815...70,692,679
JBrowse link
G PGK1 phosphoglycerate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr  X:62,187,472...62,210,321
Ensembl chr  X:62,187,431...62,212,244
JBrowse link
G PHB prohibitin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr12:25,596,520...25,609,693
Ensembl chr12:25,584,443...25,609,656
JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:39,309,701...39,319,313
Ensembl chr 5:39,314,595...39,315,761
JBrowse link
G PIGE-108A11.3 leukocyte immunoglobulin-like receptor-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:59,042,881...59,046,646 JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha severity
no_association
susceptibility
ISO DNA:mutations:exons:
DNA:mutation:exon:
DNA:SNPs: :rs17849071,rs17849079(human)
OMIM
RGD
PMID:16331247, PMID:24673525, PMID:26823876 RGD:11556371, RGD:14402404, RGD:14402405 NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,277,232
JBrowse link
G PITPNM3 PITPNM family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:50,806,302...50,898,316
Ensembl chr12:50,728,910...50,898,336
JBrowse link
G PITX1 paired like homeodomain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:137,200,424...137,212,500
Ensembl chr 2:137,198,870...137,206,979
JBrowse link
G PKM pyruvate kinase, muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 7:60,971,807...61,032,780 JBrowse link
G PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:39,201,819...39,209,261
Ensembl chr 3:39,201,878...39,209,263
JBrowse link
G PKP1 plakophilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr10:23,689,394...23,735,457
Ensembl chr10:23,689,380...23,735,453
JBrowse link
G PLAC8 placenta associated 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:135,250,761...135,279,091 JBrowse link
G PLK1 polo like kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:22,537,814...22,550,901
Ensembl chr 3:22,537,816...22,555,023
JBrowse link
G PLK4 polo like kinase 4 sexual_dimorphism ISO DNA:hypermethylation:promoter RGD PMID:21324136 RGD:27226690 NCBI chr 8:96,989,011...97,013,324
Ensembl chr 8:96,991,940...97,090,023
JBrowse link
G PLVAP plasmalemma vesicle associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:60,324,565...60,344,450
Ensembl chr 2:60,324,560...60,344,448
JBrowse link
G PLXDC1 plexin domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:23,073,292...23,142,529
Ensembl chr12:23,073,287...23,142,548
JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 ISO associated with Hepatitis C, Chronic;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:21319195 RGD:14981585 NCBI chr 5:5,075,608...5,092,599
Ensembl chr 5:5,075,622...5,092,515
JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 3:85,595,356...85,639,665
Ensembl chr 3:85,595,392...85,639,690
JBrowse link
G POLG DNA polymerase gamma, catalytic subunit susceptibility ISO DNA:SNPs:introns: (rs1061316, rs758130) (human) RGD PMID:28457473 RGD:15039387 NCBI chr 7:54,889,150...54,907,167
Ensembl chr 7:54,889,153...54,906,856
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha susceptibility ISO associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human) RGD PMID:19119483 RGD:15042881 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma severity ISO protein:decreased expression:liver
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:16374840, PMID:27451128 RGD:14694822 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr 8:55,652,194...55,701,077
Ensembl chr 8:55,652,201...55,701,077
JBrowse link
G PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15010824 NCBI chr 5:19,753,850...19,763,281
Ensembl chr 5:19,753,847...19,763,288
JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A onset ISO protein:increased expression:liver (rat) RGD PMID:20935162 RGD:10002734 NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,280...74,940,362
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B severity ISO mRNA, protein:decreased expression:liver (human) RGD PMID:23591196 RGD:10043803 NCBI chr12:26,319,123...26,337,089
Ensembl chr12:26,319,124...26,336,562
JBrowse link
G PRC1 protein regulator of cytokinesis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:55,869,749...55,900,640
Ensembl chr 7:55,840,723...56,045,582
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,520...165,861,442
JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,796...66,213,567
JBrowse link
G PRDX6 peroxiredoxin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 9:115,857,629...115,868,898
Ensembl chr 9:115,857,644...115,868,892
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase severity ISO protein:decreased expression:liver (human) RGD PMID:28862485 RGD:13432206 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,511...6,730,881
JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27022031 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 severity
susceptibility
ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver, cytosol
DNA:SNP:promoter:-1195A>G (rs689466) (human)
mRNA,protein:decreased expression:liver
RGD
CTD
PMID:11872629, PMID:12024111, PMID:14563831, PMID:15800977, PMID:16374840, PMID:17510421, PMID:18373278, PMID:24720952, PMID:24759835 RGD:14695010, RGD:14695011, RGD:14695012, RGD:2300283 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTH1R parathyroid hormone 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:29,749,940...29,775,361
Ensembl chr13:29,753,308...29,775,371
JBrowse link
G PTK2 protein tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:14578863, PMID:17203219 RGD:2292584 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,613...2,896,060
JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:63,104,698...63,112,382 JBrowse link
G PYGL glycogen phosphorylase L ISO CTD Direct Evidence: marker/mechanism CTD PMID:2885971 NCBI chr 1:180,645,849...180,704,124
Ensembl chr 1:180,620,314...180,719,979
JBrowse link
G PZP pregnancy zone protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:62,350,208...62,396,716 JBrowse link
G RAC1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18506888 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687
JBrowse link
G RACGAP1 Rac GTPase activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:15,894,314...15,943,619
Ensembl chr 5:15,904,707...15,943,614
JBrowse link
G RAD54L RAD54 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:165,156,833...165,184,641
Ensembl chr 6:165,152,978...165,184,776
JBrowse link
G RARA retinoic acid receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr12:22,047,449...22,085,759
Ensembl chr12:22,047,442...22,085,674
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12029619, PMID:14961299 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,759...19,317,690
JBrowse link
G RCAN1 regulator of calcineurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:198,106,256...198,205,727
Ensembl chr13:198,102,098...198,205,629
JBrowse link
G RECQL RecQ like helicase disease_progression ISO protein:increased expression:liver RGD PMID:18422747 RGD:2317370 NCBI chr 5:51,953,460...51,995,619
Ensembl chr 5:51,953,184...52,003,742
JBrowse link
G RGN regucalcin ISO protein:decreased expression:liver RGD PMID:21683810 RGD:5509919 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,726
JBrowse link
G RND3 Rho family GTPase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:1,715,589...1,732,605
Ensembl chr15:1,715,207...1,734,419
JBrowse link
G RNF157 ring finger protein 157 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:5,225,978...5,306,197
Ensembl chr12:5,226,135...5,307,061
JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:175,348,223...176,479,482
Ensembl chr13:175,505,366...176,479,482
JBrowse link
G RPS6 ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 1:203,444,360...203,447,643
Ensembl chr 1:203,444,450...203,451,468
JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr  X:16,452,401...16,576,854
Ensembl chr  X:16,452,405...16,575,364
JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr 9:6,026,151...6,065,211
Ensembl chr 9:6,025,063...6,065,116
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555, PMID:28284560 NCBI chr 3:126,357,198...126,367,145 JBrowse link
G RSPO3 R-spondin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:35,985,985...36,066,432
Ensembl chr 1:35,984,949...36,067,079
JBrowse link
G RTKN rhotekin ISO mRNA:increased expression:liver RGD PMID:27922690 RGD:19165144 NCBI chr 3:68,598,560...68,613,633
Ensembl chr 3:68,598,236...68,613,633
JBrowse link
G RTP3 receptor transporter protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17693185 NCBI chr13:29,471,568...29,476,277 JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28458013 NCBI chr 6:82,531,203...82,595,044
Ensembl chr 6:82,531,215...82,595,026
JBrowse link
G RXRA retinoid X receptor alpha ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26619011 NCBI chr 1:273,698,842...273,797,622
Ensembl chr 1:273,705,503...273,797,622
JBrowse link
G SCAP SREBF chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr13:30,253,262...30,320,625
Ensembl chr13:30,253,268...30,320,526
JBrowse link
G SCD stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr14:111,461,560...111,478,033
Ensembl chr14:111,461,560...111,478,031
JBrowse link
G SERPINA1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6258829, PMID:21472284 NCBI chr 7:115,604,282...115,616,915
Ensembl chr 7:115,604,285...115,614,633
JBrowse link
G SERPINB5 serpin family B member 5 disease_progression ISO associated with hepatitis B; RGD PMID:26296971 RGD:11520929 NCBI chr 1:158,167,756...158,195,896
Ensembl chr 1:158,167,643...158,195,796
JBrowse link
G SERPINF1 serpin family F member 1 ISO associated with Human Viral Hepatitis, liver cirrhosis;protein:increased expression:serum (human) RGD PMID:27748324 RGD:27226704 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,943,051...47,959,472
JBrowse link
G SET SET nuclear proto-oncogene ISO ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26822237 NCBI chr 1:269,050,447...269,064,462 JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:23634996, PMID:26619011 NCBI chr15:101,274,968...101,338,018
Ensembl chr15:101,191,854...101,338,023
JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:26619011 NCBI chr 2:6,279,039...6,295,550
Ensembl chr 2:6,279,048...6,294,640
JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748
JBrowse link
G SHC1 SHC adaptor protein 1 ISO protein:increased expression, increased phosphorylation:hepatocyte RGD PMID:15375560 RGD:1643188 NCBI chr 4:94,818,226...94,831,766
Ensembl chr 4:94,810,875...94,831,765
JBrowse link
G SHH sonic hedgehog signaling molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,718...2,555,484
JBrowse link
G SIX1 SIX homeobox 1 severity ISO protein:increased expression:liver (human) RGD PMID:17008870 RGD:11561961 NCBI chr 1:189,620,430...189,624,652
Ensembl chr 1:189,619,853...189,628,187
JBrowse link
G SKA1 spindle and kinetochore associated complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:99,976,354...99,993,492
Ensembl chr 1:99,976,485...99,993,462
JBrowse link
G SKA3 spindle and kinetochore associated complex subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:1,302,880...1,321,132
Ensembl chr11:1,302,886...1,320,981
JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
CTD
RGD
PMID:12717389, PMID:19533683 RGD:2315050 NCBI chr16:21,463,270...21,500,925
Ensembl chr16:21,463,012...21,502,550
JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:7,340,442...7,365,543
Ensembl chr 1:7,340,116...7,365,520
JBrowse link
G SLC25A47 solute carrier family 25 member 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:121,204,213...121,210,376
Ensembl chr 7:121,192,433...121,210,377
JBrowse link
G SLC26A6 solute carrier family 26 member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:31,319,287...31,330,649
Ensembl chr13:31,317,877...31,330,602
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G SLC2A2 solute carrier family 2 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr13:109,592,595...109,614,105
Ensembl chr13:109,587,256...109,623,787
JBrowse link
G SLC5A5 solute carrier family 5 member 5 ISO CTD Direct Evidence: therapeutic CTD PMID:15347726, PMID:15520214 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,154...59,885,265
JBrowse link
G SLIT2 slit guidance ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19100240 NCBI chr 8:14,758,426...15,149,515
Ensembl chr 8:14,756,619...15,149,510
JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:18971187 RGD:12880056 NCBI chr 1:97,415,360...97,511,388
Ensembl chr 1:97,415,716...97,511,358
JBrowse link
G SMAD4 SMAD family member 4 disease_progression ISO protein:increased expression:liver:
protein:decreased expression:liver
RGD PMID:18971187, PMID:22799322, PMID:23922662, PMID:29924446 RGD:12880056, RGD:18182921, RGD:21066341, RGD:21066342 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,514,791...100,628,029
JBrowse link
G SMAD7 SMAD family member 7 ISO mRNA:increased expression:liver (human) RGD PMID:25602745 RGD:14401589 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,510,229...98,542,382
JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E ISO human gene in a mouse model RGD PMID:21688285 RGD:10768833 NCBI chr 9:64,560,544...64,567,007
Ensembl chr 9:64,560,515...64,567,025
JBrowse link
G SNW1 SNW domain containing 1 severity ISO protein:increased expression:liver (human) RGD PMID:23696020 RGD:11035253 NCBI chr 7:100,718,298...100,749,414
Ensembl chr 7:100,718,036...100,749,356
JBrowse link
G SOAT2 sterol O-acyltransferase 2 ISO RGD PMID:16274362 RGD:1581190 NCBI chr 5:18,358,941...18,371,262
Ensembl chr 5:18,358,673...18,371,264
JBrowse link
G SOCS2 suppressor of cytokine signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:89,581,081...89,587,424
Ensembl chr 5:89,242,169...89,586,239
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16831601 NCBI chr12:3,643,832...3,647,015
Ensembl chr12:3,643,929...3,647,012
JBrowse link
G SOD2 superoxide dismutase 2 disease_progression
susceptibility
ISO protein:increased expression:saliva
associated with liver cirrhosis; DNA:SNP:cds:p.Ala16Val(rs1799725)(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15869407, PMID:16767786, PMID:18760346, PMID:19731237, PMID:21472284, PMID:27221200, PMID:31041878 RGD:1581242, RGD:26923907, RGD:26923955, RGD:27095881 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,651,280...7,691,723
JBrowse link
G SPAG9 sperm associated antigen 9 ISO associated with Human Viral Hepatitis RGD PMID:29344208 RGD:30296654 NCBI chr12:27,225,377...27,370,337
Ensembl chr12:27,198,946...27,425,463
JBrowse link
G SPC25 SPC25 component of NDC80 kinetochore complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:75,339,171...75,371,275
Ensembl chr15:75,336,510...75,371,280
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16047475 RGD:1581375 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
G SPRTN SprT-like N-terminal domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25261934 NCBI chr14:59,177,801...59,192,221
Ensembl chr14:59,171,170...59,192,270
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563831, PMID:21147110 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,265
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,487...6,784,672
JBrowse link
G SRF serum response factor ISO RGD PMID:9570363 RGD:1581428 NCBI chr 7:38,213,300...38,223,686
Ensembl chr 7:38,213,063...38,222,140
JBrowse link
G SRPX sushi repeat containing protein X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:34,075,577...34,198,462
Ensembl chr  X:34,075,577...34,198,467
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO mRNA:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr12:34,278,363...34,282,164
Ensembl chr12:34,272,068...34,282,137
JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO protein:increased activity:liver: RGD PMID:9331085 RGD:10043141 NCBI chr13:124,699,622...124,837,847
Ensembl chr13:124,700,133...124,837,843
JBrowse link
G STAB2 stabilin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:80,692,459...80,863,221 JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22488367 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
JBrowse link
G STAT4 signal transducer and activator of transcription 4 susceptibility ISO CTD Direct Evidence: marker/mechanism
Hepatitis B, Chronic; DNA:SNP: intron 3: (rs7574865) (human)
CTD
RGD
PMID:23242368, PMID:26745093 RGD:11553302 NCBI chr15:95,656,206...95,764,099
Ensembl chr15:95,653,861...95,763,448
JBrowse link
G STMN1 stathmin 1 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28284560, PMID:28982915 RGD:21408578 NCBI chr 6:83,356,404...83,362,546
Ensembl chr 6:83,356,411...83,362,500
JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:825,433...835,425 JBrowse link
G TAGLN2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 4:90,566,272...90,574,762 JBrowse link
G TALDO1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chr 2:464,781...472,836
Ensembl chr 2:435,125...473,744
JBrowse link
G TATDN1 TatD DNase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 4:15,113,318...15,159,501
Ensembl chr 4:15,113,037...15,159,499
JBrowse link
G TCF19 transcription factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:23,558,326...23,562,074
Ensembl chr 7:23,558,384...23,562,069
JBrowse link
G TCIM transcriptional and immune response regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:9,441,488...9,443,053
Ensembl chr17:9,441,766...9,442,086
JBrowse link
G TEDC2 tubulin epsilon and delta complex 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:39,580,181...39,584,414
Ensembl chr 3:39,580,200...39,584,386
JBrowse link
G TEK TEK receptor tyrosine kinase ISO protein:increased expression RGD PMID:16951510 RGD:1601490 NCBI chr 1:195,938,177...196,052,294
Ensembl chr 1:195,937,394...196,051,957
JBrowse link
G TERT telomerase reverse transcriptase treatment
disease_progression
no_association
susceptibility
ISO DNA:hypermethylation:promoter
ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:SNP,mutations:promoter:rs2853669 (-245T >C), (-124C > T),(-146C > T)human
DNA:mutations, polymorphisms:promoter,intron, exon:rs2736100,rs2736098(human)
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased localization:nucleus
DNA:mutations:promoter:
RGD
ClinVar
CTD
PMID:16651430, PMID:17175353, PMID:19184104, PMID:20353272, PMID:22634754, PMID:23000435, PMID:25123086, PMID:25362482, PMID:25683523, PMID:25741868, PMID:25822088, PMID:26575952, PMID:28416747, PMID:28492532, PMID:28677271 RGD:11038673, RGD:11530743, RGD:11564803, RGD:14696767, RGD:14696768, RGD:14696769, RGD:14696770 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 ISO protein:decreased expression:liver RGD PMID:23671639 RGD:9586747 NCBI chr14:71,675,671...71,812,732
Ensembl chr14:71,675,671...71,815,621
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17464989, PMID:28284560 NCBI chr 9:73,684,236...73,694,663
Ensembl chr 9:73,673,535...73,689,095
JBrowse link
G TFRC transferrin receptor ISO mRNA:increased expression:liver RGD PMID:16953838 RGD:2292036 NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,594...134,000,278
JBrowse link
G TGFA transforming growth factor alpha ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9029167, PMID:9060843, PMID:15565109 RGD:2317471 NCBI chr 3:71,948,232...72,054,257
Ensembl chr 3:71,948,137...72,050,488
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029167 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO mRNA, protein:decreased expression:liver RGD PMID:14585397 RGD:1601598 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,491...16,878,165
JBrowse link
G TGM3 transglutaminase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:33,191,901...33,236,065 JBrowse link
G TH tyrosine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,618...1,506,615
JBrowse link
G THY1 Thy-1 cell surface antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:46,607,022...46,612,691
Ensembl chr 9:46,607,494...46,612,269
JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:55,142,957...55,200,259
Ensembl chr 7:55,143,240...55,200,641
JBrowse link
G TIMD4 T cell immunoglobulin and mucin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:66,253,572...66,292,963
Ensembl chr16:66,253,604...66,292,961
JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:3,785,997...3,794,824
Ensembl chr12:3,635,220...3,795,917
JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO DNA:deletion:promoter:-196 to -174(human)
associated with Hepatitis C, Chronic;DNA:deletion:promoter:-196 to -174(human)
RGD PMID:21500195, PMID:22859216, PMID:27183918 RGD:15090813, RGD:15090815, RGD:18337266 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
G TLR3 toll like receptor 3 disease_progression ISO RGD PMID:23197495 RGD:21079421 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,966,040...47,058,734
JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:SNP: :rs1057317(human)
protein:increased expression:liver:
CTD Direct Evidence: marker/mechanism
DNA:SNPs, haplotype: :multiples
RGD
CTD
PMID:21559380, PMID:25179842, PMID:27022031, PMID:28578348 RGD:14700552, RGD:14700557, RGD:14700558 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TLR9 toll like receptor 9 treatment ISO human cells in a mouse model
protein: increased expression:peripheral blood mononuclear cell (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18215354, PMID:24452201, PMID:24990399 RGD:18337468, RGD:18337472 NCBI chr13:34,353,444...34,370,990 JBrowse link
G TMEM70 transmembrane protein 70 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr 4:61,958,605...61,966,041
Ensembl chr 4:61,958,602...61,966,027
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:26890368, PMID:27022031 RGD:14975171 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:17326159 NCBI chr13:111,021,952...111,103,060
Ensembl chr13:110,981,604...111,107,423
JBrowse link
G TNFSF9 TNF superfamily member 9 ISO RGD PMID:17325342 RGD:2317348 NCBI chr 2:72,578,811...72,582,834
Ensembl chr 2:72,578,821...72,582,745
JBrowse link
G TONSL tonsoku like, DNA repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:349,992...361,749
Ensembl chr 4:348,652...362,200
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:22,001,300...22,028,452
Ensembl chr12:22,001,336...22,028,454
JBrowse link
G TP53 tumor protein p53 ISO OMIM NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G TPX2 TPX2 microtubule nucleation factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:35,431,271...35,484,814
Ensembl chr17:35,431,370...35,484,760
JBrowse link
G TRAIP TRAF interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:32,332,336...32,380,988
Ensembl chr13:32,332,339...32,379,766
JBrowse link
G TRIM24 tripartite motif containing 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr18:11,055,211...11,151,755
Ensembl chr18:11,055,208...11,151,404
JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:79,458,843...79,473,705
Ensembl chr16:79,458,847...79,473,712
JBrowse link
G TROAP trophinin associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:15,300,688...15,307,681
Ensembl chr 5:15,300,451...15,307,697
JBrowse link
G TSC1 TSC complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21499249 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,952
JBrowse link
G TSC2 TSC complex subunit 2 severity ISO protein:decreased expression:liver (human) RGD PMID:24119083 RGD:21079731 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,922...39,937,371
JBrowse link
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:115,832,152...115,837,572 JBrowse link
G TST thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 5:10,749,264...10,759,623
Ensembl chr 5:10,746,890...10,759,623
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:45,829,014...45,838,978
Ensembl chr 9:45,829,191...45,838,979
JBrowse link
G TTK TTK protein kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:86,076,576...86,125,334
Ensembl chr 1:86,076,583...86,125,718
JBrowse link
G TYMS thymidylate synthetase susceptibility ISO DNA:deletion:3'UTR:1494del6(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17659576, PMID:18019677, PMID:18230555 RGD:14696708 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,640,031...105,660,601
JBrowse link
G UBD ubiquitin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 7:22,501,130...22,502,883
Ensembl chr 7:22,501,130...22,503,094
JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:48,018,403...48,021,542
Ensembl chr17:48,018,400...48,021,534
JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr13:9,998,097...10,380,564
Ensembl chr13:9,998,176...10,380,564
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:24,454,492...24,459,085
Ensembl chr10:24,454,495...24,459,057
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18666234 NCBI chr 8:32,353,766...32,367,288
Ensembl chr 8:32,353,246...32,367,323
JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:73,898,061...73,937,727
Ensembl chr 2:73,898,085...73,935,682
JBrowse link
G UMPS uridine monophosphate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr13:135,611,857...135,650,656
Ensembl chr13:135,610,058...135,650,604
JBrowse link
G UROC1 urocanate hydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:53,592,763...53,634,214
Ensembl chr 7:53,590,776...53,637,714
JBrowse link
G USP2 ubiquitin specific peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 9:46,563,469...46,590,392
Ensembl chr 9:46,563,480...46,590,265
JBrowse link
G VASN vasorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25826090 NCBI chr 3:37,961,425...37,972,477
Ensembl chr 3:37,961,425...37,972,115
JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO mRNA:decreased expression:liver RGD PMID:2064726 RGD:2306008 NCBI chr 2:72,327,433...72,391,649
Ensembl chr 2:72,326,714...72,391,648
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,908...117,511,226
JBrowse link
G VDR vitamin D receptor susceptibility ISO associated with alcoholic liver cirrhosis;DNA:haplotype::
associated with Hepatitis B, Chronic;DNA:SNP: :rs2228570(human)
DNA:hypermethylation:promoter
RGD PMID:20572305, PMID:25541958, PMID:29432829 RGD:14401747, RGD:14402025, RGD:14402026 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,267,321
JBrowse link
G VEGFA vascular endothelial growth factor A treatment
disease_progression
ISO DNA:polymorphism:promoter:-2578C>A (rs699947)(human)
protein:increased expression:liver
protein:increased expression:serum:
associated with liver cirrhosis;
associated with liver cirrhosis; protein:increased expression:platelet, liver:
RGD PMID:16835748, PMID:18392108, PMID:18544126, PMID:26930285, PMID:27338800, PMID:28147320 RGD:11527070, RGD:15003194, RGD:15003196, RGD:15003200, RGD:15014783, RGD:15036790 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
G VEGFC vascular endothelial growth factor C ISO associated with liver cirrhosis; protein:increased expression:liver: RGD PMID:18544126 RGD:15003200 NCBI chr15:39,037,764...39,136,234
Ensembl chr15:39,037,893...39,133,041
JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:26,036,610...26,073,168
Ensembl chr13:26,036,629...26,075,691
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:52,175,601...52,198,635
Ensembl chr  X:52,175,605...52,198,621
JBrowse link
G WDR62 WD repeat domain 62 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:45,418,966...45,477,619
Ensembl chr 6:45,419,041...45,474,050
JBrowse link
G WDR76 WD repeat domain 76 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:127,651,765...127,741,357
Ensembl chr 1:127,652,887...127,741,354
JBrowse link
G WNT2 Wnt family member 2 susceptibility ISO associated with hepatitis B;DNA:SNP: :rs4730775(human) RGD PMID:28328801 RGD:14402040 NCBI chr18:28,945,825...28,993,969
Ensembl chr18:28,946,277...29,028,107
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 ISO RNA:increased expression:liver: RGD PMID:26551349 RGD:11096781 NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,974,741
JBrowse link
G XDH xanthine dehydrogenase ISO protein:decreased activity:tumor (rat) RGD PMID:179860 RGD:5135059 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,986,528...108,080,151
JBrowse link
G XPO5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24676133 RGD:11041737 NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,530,725...38,569,570
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
severity
no_association
ISO DNA:missense mutation:cds:c.1804C>A (p.G506A) (human)
DNA:silent mutation, missense mutation:cds:c.1161G>A, c.1779C>G (p.L387L, p.S593R) (human)
DNA:missense mutations:cds:c.482C>T, c.1178G>A (p.P161L, p.R393H) (human)
associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human)
DNA:missense mutation:cds:p.R399Q (rs25487) (human)
DNA:missense mutation:cds:p.R399Q (human)
DNA:missense mutations:cds:p.R194W, p.R280H, p.R399Q (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human)
DNA:SNPs:exons:c.1254C>T, c.1517G>C (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R399Q (human)
DNA:missense mutation:cds:p.R399Q (28152G>A) (rs25487) (human)
RGD PMID:14519756, PMID:19194663, PMID:22502666, PMID:23454624, PMID:23493666, PMID:23534753, PMID:23984316, PMID:24526467, PMID:24570146, PMID:26918371, PMID:28058700, PMID:29682247, PMID:29935355 RGD:14696702, RGD:14696772, RGD:14696773, RGD:14985238, RGD:14985240, RGD:14985242, RGD:14985243, RGD:15014789, RGD:15014790, RGD:15014791, RGD:15014792, RGD:15036794, RGD:15036797 NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,686...50,425,710
JBrowse link
G YAP1 Yes1 associated transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29698666 NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,416...32,925,603
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28104805 NCBI chr 6:85,717,147...85,756,750
Ensembl chr 6:85,716,917...85,751,583
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta severity ISO RGD PMID:27811373 RGD:14700875 NCBI chr 4:35,975,513...36,009,909
Ensembl chr 4:35,975,541...36,009,777
JBrowse link
G ZFP36 ZFP36 ring finger protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:48,063,732...48,066,235
Ensembl chr 6:48,052,137...48,066,257
JBrowse link
G ZIC2 Zic family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:68,840,802...68,845,441
Ensembl chr11:68,840,830...68,846,470
JBrowse link
G ZIC4 Zic family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:87,725,642...87,740,724
Ensembl chr13:87,722,067...87,742,262
JBrowse link
G ZIC5 Zic family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:68,821,733...68,830,472
Ensembl chr11:68,821,735...68,830,341
JBrowse link
G ZNF23 zinc finger protein 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21965783 NCBI chr 6:14,463,135...14,480,783
Ensembl chr 6:14,463,304...14,480,864
JBrowse link
G ZWINT ZW10 interacting kinetochore protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:94,094,781...94,109,447
Ensembl chr14:94,094,887...94,109,532
JBrowse link
adult hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:17611497, PMID:18256540, PMID:18392055, PMID:18504432, PMID:18611285, PMID:19418217, PMID:19487299, PMID:19853286, PMID:20233444, PMID:20453058, PMID:21464312, PMID:21512767, PMID:21793738, PMID:22538770, PMID:22610119, PMID:22722201, PMID:22722839, PMID:22980975, PMID:23237847, PMID:23348505, PMID:23700467, PMID:23728071, PMID:23934607, PMID:24190505, PMID:24657128, PMID:25157968, PMID:26619011, PMID:28492532
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:24728327, PMID:25479140, PMID:25741868, PMID:26530882, PMID:28492532 NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912
JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:21390126, PMID:21680795, PMID:21796119, PMID:22832583, PMID:23334668, PMID:23685749, PMID:23778141, PMID:26087898, PMID:26619011, PMID:27257180, PMID:28492532, PMID:29551561 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,230
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:9065402, PMID:9065403, PMID:9294210, PMID:9500465, PMID:9927029, PMID:10027390, PMID:10192393, PMID:10391090, PMID:10398436, PMID:10435629, PMID:10655994, PMID:10666372, PMID:11351304, PMID:11930117, PMID:11950921, PMID:12124804, PMID:15133491, PMID:24788118, PMID:25157968, PMID:26619011, PMID:26822237 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,137,173...25,208,311
JBrowse link
G GNAS GNAS complex locus ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:1594625, PMID:1944469, PMID:2549426, PMID:3720010, PMID:7739708, PMID:8766942, PMID:9626141, PMID:12727968, PMID:12970318, PMID:15126527, PMID:16507630, PMID:21835143, PMID:23536913, PMID:24855271, PMID:25157968, PMID:26619011 NCBI chr17:58,985,580...59,053,022
Ensembl chr17:58,998,981...59,053,021
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:11150980, PMID:12210337, PMID:12835555, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17211612, PMID:17250658, PMID:17384584, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18042262, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19213030, PMID:19255327, PMID:19371735, PMID:19382114, PMID:19669404, PMID:19773371, PMID:20660566, PMID:20859122, PMID:20979192, PMID:21438134, PMID:21495179, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22256804, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22726224, PMID:22926243, PMID:23093928, PMID:23096712, PMID:23406027, PMID:23429430, PMID:23751039, PMID:23884457, PMID:24006476, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:24390138, PMID:25157968, PMID:25326635, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759, PMID:168335863 NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:18772396, PMID:19657110, PMID:19798509, PMID:19818334, PMID:20946881, PMID:21352804, PMID:21446021, PMID:22160010, PMID:22397365, PMID:22417203, PMID:22898539, PMID:23558169, PMID:24606448, PMID:25043048, PMID:25157968, PMID:25741868, PMID:26619011 NCBI chr15:111,341,153...111,362,330
Ensembl chr15:111,341,152...111,362,280
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO ClinVar Annotator: match by term: Hepatocellular carcinoma, adult ClinVar PMID:20946881, PMID:21250968, PMID:21596855, PMID:21997850, PMID:22160010, PMID:22397365, PMID:22417203,