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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:bronchitis
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Accession:DOID:6132 term browser browse the term
Definition:Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.
Synonyms:exact_synonym: Bronchitides;   CI - Chest infection;   Chest infection;   acute Bronchitis;   chest cold;   chronic bronchitis;   recurrent wheezy bronchitis
 narrow_synonym: RECURRENT BRONCHITIS
 related_synonym: acute bronchitis and bronchiolitis
 primary_id: MESH:D001991;   RDO:0001810
 xref: ICD10CM:J20;   ICD10CM:J20.9;   ICD10CM:J40;   ICD10CM:J42;   ICD9CM:466.0;   ICD9CM:490;   ICD9CM:491;   NCI:C26722;   NCI:C26932;   NCI:C2911
For additional species annotation, visit the Alliance of Genome Resources.



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bronchitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO DNA:polymorphism (human) RGD PMID:14593914 RGD:4889126 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Egr1 early growth response 1 ISO RGD PMID:17384085 RGD:5132266 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Hdac2 histone deacetylase 2 treatment IEP RGD PMID:22708526 RGD:9590258 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Ifng interferon gamma resistance ISO RGD PMID:20953328 RGD:4145525 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
bronchiolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:17687719 RGD:4145098 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 severity ISO protein:increased expression:nasal mucus
associated with Respiratory Syncytial Virus Infections
RGD PMID:17297249 PMID:15681407 RGD:4145460, RGD:4145415 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:19470255 RGD:5132271 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd86 CD86 molecule ISO protein:decreased expression:myeloid dendritic cell (mouse) RGD PMID:20046053 RGD:4892291 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Crp C-reactive protein severity ISO RGD PMID:21284715 RGD:5131282 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO associated with Pneumovirus Infections RGD PMID:16337014 RGD:4843953 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Il17a interleukin 17A susceptibility ISO DNA:SNP:promoter:rs2275913 (human) RGD PMID:20437253 RGD:4889139 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung RGD PMID:8608647 RGD:4143192 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:lung RGD PMID:8608647 RGD:4143192 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO DNA:polymorphisms:promoter:rs885454,rs17235353, rs7115457 (human) RGD PMID:15709052 RGD:7349353 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
JBrowse link
bronchiolitis obliterans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP RGD PMID:17097496 RGD:4140933 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Adora2a adenosine A2a receptor ISO RGD PMID:19766783 RGD:4890362 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO RGD PMID:18785972 RGD:4145604 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:14611812 RGD:2307195 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO RGD PMID:20628341 RGD:4891471 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP
IMP
mRNA:increased expression:lung (rat) RGD PMID:19840961 PMID:14611812 RGD:4889978, RGD:2307195 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 IEP protein:increased expression:bronchoalveolar Lavage fluid RGD PMID:22215510 RGD:6483763 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:trachea: RGD PMID:11518728 RGD:4145124 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd86 CD86 molecule IMP RGD PMID:11266944 RGD:2307206 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Csf2 colony stimulating factor 2 IEP associated with Respiratory Aspiration;protein:increased expression:serum RGD PMID:18557728 RGD:2317286 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:16709871 PMID:12097412 PMID:12097412 RGD:5135441, RGD:5135451, RGD:5135451 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:12097412 PMID:12097412 RGD:5135451, RGD:5135451 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:16709871 PMID:12097412 PMID:12097412 RGD:5135441, RGD:5135451, RGD:5135451 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:16709871 PMID:12097412 RGD:5135441, RGD:5135451 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Edn1 endothelin 1 ISO human gene in a rat model RGD PMID:9595474 RGD:8662402 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Foxp3 forkhead box P3 IEP mRNA:increased expression:lung RGD PMID:19840961 RGD:4889978 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Gzmb granzyme B ISO RGD PMID:19737140 RGD:5135518 NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:12973103 RGD:4145412 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: therapeutic CTD PMID:16137903 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:bronchoalveolar lavage fluid RGD PMID:17182591 RGD:4146242 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO RGD PMID:17182591 RGD:4146242 NCBI chr  X:115,348,860...115,408,682
Ensembl chr  X:115,348,860...115,408,681
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO RGD PMID:17182591 RGD:4146242 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il17a interleukin 17A ISO mRNA:increased expression:trachea RGD PMID:20393404 RGD:4143277 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:lung RGD PMID:11889437 RGD:4143176 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il4 interleukin 4 IEP protein:increased expression:serum RGD PMID:18557728 RGD:2317286 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 ISO RGD PMID:20393404 RGD:4143277 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mbl2 mannose binding lectin 2 resistance ISO DNA:transversion:5' utr:-290C>G rs7096206 (human) RGD PMID:19104434 RGD:4889456 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression, increased activity:bronchoalveolar lavage fluid RGD PMID:20417130 RGD:5130759 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:16969297 RGD:5131273 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO RGD PMID:18158963 RGD:5131450 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with lung transplantation; protein:increased expression:lung RGD PMID:11112135 RGD:4892082 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 IEP protein:increased expression:lung RGD PMID:15136885 RGD:4892068 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO associated with lung transplantation; protein:decreased expression:serum,bronchoalveolar lavage RGD PMID:11981419 RGD:5147386 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Sftpd surfactant protein D ISO RGD PMID:18347569 RGD:4143500 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927
JBrowse link
G Tlr9 toll-like receptor 9 ISO DNA:SNPs:promoter, 3' utr:g.-1485C>T (rs187084), rs352162 (human) RGD PMID:20227302 RGD:5130722 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
Chronic Bronchitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 ISO RGD PMID:11991282 RGD:4145442 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :F508del(human)
associated with pulmonary disease chronic obstructive; DNA:missense mutation:exon:p.R75Q(human)
RGD PMID:10767489 PMID:15463907 RGD:4140484, RGD:4140475 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNPs: :multiple (human) RGD PMID:19386687 RGD:4891509 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 susceptibility ISO DNA:polymorphism (human) RGD PMID:15928955 RGD:4142512 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO DNA:polymorphism (human) RGD PMID:14593914 RGD:4889126 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Edn1 endothelin 1 ISO Chronic Allergic Airway Inflammation; protein:increased secretion:bronchoalveolar lavage (mouse) RGD PMID:18631350 RGD:4145074 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Gc GC, vitamin D binding protein susceptibility ISO RGD PMID:12096683 RGD:5129516 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gstm1 glutathione S-transferase mu 1 severity ISO DNA:deletion: :
DNA:deletion, haplotype: : (human)
RGD PMID:9187680 PMID:15125256 RGD:4142513, RGD:12798508 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:15928955 RGD:4142512 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:bronchial epithelium (rat) RGD PMID:19507274 RGD:2308951 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 IEP protein:decreased expression:lung RGD PMID:19507274 RGD:2308951 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:Respiratory Mucosa RGD PMID:14582911 RGD:4759835 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il15 interleukin 15 ISO mRNA, protein:increased expression:lung RGD PMID:11742275 RGD:4990461 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Mpo myeloperoxidase IEP protein:increased expression:lung RGD PMID:11798689 RGD:5130990 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nos2 nitric oxide synthase 2 IDA RGD PMID:19938219 RGD:4891494 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19263519 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
cryptogenic organizing pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung, macrophage (human) RGD PMID:21144722 RGD:5131112 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:lung, lymphocyte (human) RGD PMID:21144722 RGD:5131112 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
Diffuse Panbronchiolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:SNP:exon:p.G54D(rs1800450)(human) RGD PMID:15249448 RGD:8693755 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO protein:decreased expression:bronchiole epithelium RGD PMID:15364771 RGD:7364741 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO DNA:insertion/deletion RGD PMID:15709052 RGD:7349353 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
JBrowse link
G Mucl3 mucin like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22152429 NCBI chr20:3,100,652...3,108,569
Ensembl chr20:3,100,679...3,108,569
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 susceptibility ISO DNA:polymorphism:cds:HLA-B*5401 (human) RGD PMID:9731015 RGD:1331522 NCBI chr20:4,905,309...4,914,593 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphisms:exon: RGD PMID:10323341 RGD:5147847 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
Viral Bronchiolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam33 ADAM metallopeptidase domain 33 susceptibility ISO DNA:SNP: :rs2787094 c.2891G>C (human) RGD PMID:19258923 RGD:4142862 NCBI chr 3:118,262,395...118,283,461
Ensembl chr 3:118,271,029...118,283,461
JBrowse link
G Bcl2 BCL2, apoptosis regulator severity ISO protein:increased expression:natural killer cell, T cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 severity ISO protein:increased expression:natural killer cell,t cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G C3 complement C3 resistance ISO RGD PMID:19258923 PMID:12235218 RGD:4142862, RGD:5129513 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Casp1 caspase 1 ISO RGD PMID:15196254 RGD:5130189 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cat catalase ISO protein:decreased expression:nasal mucus RGD PMID:21471094 RGD:5130770 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO protein:increased secretion:serum (human)
DNA:snp:5' utr:g.-28C>G (human)
RGD PMID:19005677 PMID:19099677 RGD:4891884, RGD:4891881 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cd14 CD14 molecule ISO DNA:polymorphism:promoter:c.-550C>T (human) RGD PMID:17471431 RGD:4144210 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd274 CD274 molecule treatment ISO mRNA:increased expression:lung RGD PMID:22797302 PMID:22797302 RGD:40818270, RGD:40818270 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Csf2 colony stimulating factor 2 ISO protein:increased expression:nasal mucus RGD PMID:20088864 RGD:4143440 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO DNA:SNP: :p.T280M (human) RGD PMID:18257903 PMID:16645504 RGD:4891891, RGD:4891905 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP
ISO
mRNA:increased expression:lung
protein:increased expression:plasma
RGD PMID:12909590 PMID:20561238 RGD:2311388, RGD:5135493 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:20561238 RGD:5135493 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Fas Fas cell surface death receptor severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Ifnl1 interferon, lambda 1 exacerbates ISO associated with respiratory syncytial virus infectious disease;mRNA:increased expression:mucosa of nasopharynx (human) RGD PMID:24389019 RGD:126848743 NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235
JBrowse link
G Il15 interleukin 15 severity ISO mRNA,protein:increased expression:peripheral blood mononuclear cell,serum,dendritic cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il17a interleukin 17A susceptibility ISO DNA:SNP: :rs7747909(human) RGD PMID:17703412 RGD:4889847 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO DNA:SNP: :c.390T>C (rs315952) (human) RGD PMID:19258923 RGD:4142862 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il33 interleukin 33 ISO protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4r interleukin 4 receptor susceptibility ISO associated with respiratory syncystial virus infection; DNA:polymorphism:cds:p. Q551R (human)
DNA:SNPs: :rs1805011,rs2057768 (human)
RGD PMID:12508140 PMID:20404812 PMID:17703412 RGD:4890022, RGD:4889996, RGD:4889847 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 ISO mRNA, protein:increased expression:respiratory system fluid/secretion RGD PMID:14738241 RGD:5128668 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il9 interleukin 9 ISO RGD PMID:15051283 RGD:5128692 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
JBrowse link
G Jak3 Janus kinase 3 severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Klrk1 killer cell lectin like receptor K1 susceptibility ISO DNA:SNP,haplotypes:3'utr: (rs10772271) (human) RGD PMID:29967528 RGD:39128159 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Mpo myeloperoxidase ISO RGD PMID:7841728 RGD:5130995 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Muc1 mucin 1, cell surface associated severity ISO protein:increased expression:serum RGD PMID:19856476 RGD:5131164 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha susceptibility ISO associated with respiratory syncytial virus infectious disease;DNA:SNP:promoter: (rs2233406) (human) RGD PMID:23487427 RGD:40902982 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 susceptibility ISO DNA:SNP: :rs1060826(human) RGD PMID:17703412 RGD:4889847 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pdcd1 programmed cell death 1 ISO protein:increased expression:CD8 T cell RGD PMID:22797302 RGD:40818270 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Postn periostin ISO mRNA,protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Stat5a signal transducer and activator of transcription 5A severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Tlr4 toll-like receptor 4 ISO protein:increased expression:monocyte
protein:decreased expression:neutrophil
RGD PMID:14738455 PMID:19497921 RGD:4144819, RGD:4144183 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr5 toll-like receptor 5 susceptibility ISO DNA:snp:cds:p.F616L rs5744174 (human) RGD PMID:19258923 RGD:4142862 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:SNP: :rs1799724(human)
DNA:polymorphism:promoter: c. -308A>G (human)
protein:increased expression:nasal lavage fluid
RGD PMID:17703412 PMID:19849941 PMID:20088864 RGD:4889847, RGD:4143441, RGD:4143440 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b severity ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr15:44,839,818...44,867,582
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tslp thymic stromal lymphopoietin severity ISO mRNA, protein:increased expression:nasal mucus (human) RGD PMID:28471975 RGD:38596342 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Vdr vitamin D receptor susceptibility ISO DNA:SNP (human)
DNA:SNP: :rs10735810 (human)
RGD PMID:18266602 PMID:17703412 RGD:4889843, RGD:4889847 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18030
    disease of anatomical entity 17410
      Immune & Inflammatory Diseases 5045
        Inflammation 2741
          bronchitis 93
            Chronic Bronchitis 17
            Immotile Cilia Syndrome, due to Excessively Long Cilia 0
            bronchiolitis + 79
Path 2
Term Annotations click to browse term
  disease 18030
    disease of anatomical entity 17410
      respiratory system disease 3350
        lower respiratory tract disease 2195
          lung disease 2152
            obstructive lung disease 453
              bronchitis 93
                Chronic Bronchitis 17
                Immotile Cilia Syndrome, due to Excessively Long Cilia 0
                bronchiolitis + 79
paths to the root