Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:congestive heart failure
go back to main search page
Accession:DOID:6000 term browser browse the term
Definition:A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Synonyms:exact_synonym: CHF;   Cardiac Failure;   Cardiac Failure Congestive;   Congestive heart disease;   Heart Decompensation;   Heart Failure;   Left Sided Heart Failure;   Myocardial Failure;   Right Sided Heart Failure;   Weak heart
 narrow_synonym: Chronic Heart Failure
 related_synonym: Beta-2-adrenoreceptor agonist, reduced response to;   Congestive heart failure and beta-blocker response, modifier of;   Congestive heart failure, modifier of
 primary_id: MESH:D006333;   RDO:0005421
 xref: ICD10CM:I50;   ICD10CM:I50.9;   ICD9CM:428;   ICD9CM:428.0;   NCI:C3080;   NCI:C50577
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
congestive heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936490:927,769...1,191,483 JBrowse link
G Acads acyl-CoA dehydrogenase short chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30827304 NCBI chrNW_004936668:257,214...272,089 JBrowse link
G Acan aggrecan ISO mRNA:increased expression:myocardium RGD PMID:24595230 RGD:11570548 NCBI chrNW_004936483:14,811,152...14,846,305 JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25973029 NCBI chrNW_004936470:4,964,526...5,011,808 JBrowse link
G Acly ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936490:16,758,001...16,798,152 JBrowse link
G Actn2 actinin alpha 2 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 NCBI chrNW_004936484:16,186,844...16,248,394 JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment ISO associated with pulmonary hypertension RGD PMID:22628376 RGD:13703064 NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:plasma
associated with cardiovascular disease; protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:18192035, PMID:19367012, PMID:22032915, PMID:26670611 RGD:5686388, RGD:5686806 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Adm adrenomedullin ISO RGD PMID:12623952 RGD:704370 NCBI chrNW_004936528:8,005,223...8,007,586 JBrowse link
G Adrb1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of
DNA:polymorphism: :p.R389G (human)
CTD
ClinVar
RGD
PMID:7586371, PMID:10212248, PMID:12374873, PMID:14502278, PMID:15816327, PMID:16844790, PMID:17496726, PMID:19587314, PMID:21516734 RGD:5129119, RGD:737774 NCBI chrNW_004936486:4,400,467...4,401,588 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
protein:altered localization:cardiac muscle cell
RGD
ClinVar
PMID:8383511, PMID:15284533, PMID:16596417, PMID:19587314, PMID:20185685 RGD:4144900, RGD:5129119 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
G Adrb3 adrenoceptor beta 3 ISO protein:increased expression:heart ventricle (rat)
CTD Direct Evidence: marker/mechanism
protein:increased expression:left ventricle, myocardium (human)
RGD
CTD
PMID:11273992, PMID:15009959, PMID:17440824, PMID:21549119 RGD:5684398, RGD:5684917 NCBI chrNW_004936710:1,410,589...1,413,279 JBrowse link
G Ager advanced glycosylation end-product specific receptor severity ISO protein:increased expression:plasma (human) RGD PMID:20685687 RGD:7244134 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
G Agt angiotensinogen onset
severity
treatment
ISO DNA:polymorphisms: :p.M235T, p.T174M (human)
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:1330361, PMID:12025466, PMID:17145981, PMID:20811386, PMID:21963897, PMID:24465706 RGD:11039412, RGD:1601140, RGD:8549482 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Agtr1 angiotensin II receptor type 1 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17208988, PMID:18214293, PMID:18586661, PMID:21963897 RGD:8549482 NCBI chrNW_004936519:6,831,096...6,873,977 JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO mRNA, protein:decreased expression:heart RGD PMID:18768398, PMID:21963897 RGD:6903846, RGD:8549482 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
G Akap6 A-kinase anchoring protein 6 ISO RGD PMID:24812305 RGD:11251930 NCBI chrNW_004936494:6,744,923...7,228,670 JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:23861362, PMID:25741868, PMID:28492532 NCBI chrNW_004936621:2,247,082...2,374,407 JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO associated with Myocardial Infarction; mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176, PMID:19546247 RGD:1642301, RGD:5509627 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Ank2 ankyrin 2 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO associated with Cardiomyopathy, Congestive RGD PMID:15238456 RGD:2314858 NCBI chrNW_004936744:776,030...781,710 JBrowse link
G Aoc3 amine oxidase copper containing 3 severity ISO protein:increased expression:plasma RGD PMID:11052858 RGD:2313827 NCBI chrNW_004936490:17,549,836...17,564,867 JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:16129801 NCBI chrNW_004936740:979,007...987,312 JBrowse link
G Apln apelin ISO associated with Hypertension, Pulmonary
protein:increased expression:ventricle myocardium
protein:decreased expression:plasma
RGD PMID:16263185, PMID:17055480, PMID:17119870 RGD:1626171, RGD:1626175, RGD:1626186 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G Apoa1 apolipoprotein A1 ISO protein: decreased expression: serum RGD PMID:17517342 RGD:5508219 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Apoc1 apolipoprotein C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
G Apoe apolipoprotein E ISO associated with Beta-Thalassemia RGD PMID:9787187 RGD:11039487 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Arrb1 arrestin beta 1 treatment ISO RGD PMID:21232674 RGD:5509888 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18418421 NCBI chrNW_004936706:476,473...494,659 JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19776660 NCBI chrNW_004936501:11,818,301...11,836,221 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:19776660, PMID:21691940 RGD:6903963 NCBI chrNW_004936558:3,300,941...3,357,595 JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12145768 NCBI chrNW_004936809:789,337...790,986 JBrowse link
G Bambi BMP and activin membrane bound inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chrNW_004936613:3,098,549...3,103,868 JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:18097624, PMID:29746994 RGD:10054097, RGD:13792577 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:18097624, PMID:29746994 RGD:10054097, RGD:13792577 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Becn1 beclin 1 treatment ISO RGD PMID:18619688 RGD:11560532 NCBI chrNW_004936490:17,518,100...17,531,126 JBrowse link
G Birc5 baculoviral IAP repeat containing 5 ISO associated with Hypertension;protein:decreased expression:cardiac muscle cell RGD PMID:16257070 RGD:2293134 NCBI chrNW_004936594:2,812,165...2,820,618 JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment ISO RGD PMID:23508759 RGD:11561982 NCBI chrNW_004936486:18,449,371...18,460,435 JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936606:2,168,104...2,867,560 JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:29746994 RGD:13792577 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G Casq2 calsequestrin 2 ISO mRNA:increased expression:sinoatrial node RGD PMID:21565973 RGD:6771208 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:10618301, PMID:16105639 RGD:1581151 NCBI chrNW_004936533:3,601,270...3,637,128 JBrowse link
G Cbl Cbl proto-oncogene ISO protein:increased expression:left ventricle myocardium, muscle cell (human) RGD PMID:24583314 RGD:11251947 NCBI chrNW_004936542:4,136,389...4,235,746 JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17229371 NCBI chrNW_004936560:42,561...45,748 JBrowse link
G Ccna2 cyclin A2 ISO RGD PMID:16820573 RGD:2293348 NCBI chrNW_004936662:1,073,460...1,079,136 JBrowse link
G Ccnt1 cyclin T1 ISO RGD PMID:15297879 RGD:1556509 NCBI chrNW_004936512:6,567,663...6,588,107 JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:15716285 RGD:2314219 NCBI chrNW_004936513:10,607,617...10,620,403 JBrowse link
G Cdk9 cyclin dependent kinase 9 ISO protein:increased activity:ventricle:
protein:increased activity:heart:
RGD PMID:15297879 RGD:1556509 NCBI chrNW_004936487:15,446,864...15,450,750 JBrowse link
G Cfd complement factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936588:350,925...352,732 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO mRNA,protein:increased expression:cardiomyocyte: RGD PMID:11033112 RGD:11341730 NCBI chrNW_004936726:381,888...425,565 JBrowse link
G Chek2 checkpoint kinase 2 ISO protein:increased phosphorylation:heart myocardium RGD PMID:12702777 RGD:2289708 NCBI chrNW_004936657:2,805,947...2,848,180 JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:plasma (human) RGD PMID:19961288 RGD:4892629 NCBI chrNW_004936567:1,411,080...1,418,332 JBrowse link
G Chrm4 cholinergic receptor muscarinic 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chrNW_004936562:2,685,209...2,687,751 JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chrNW_004936514:10,680,893...10,695,859 JBrowse link
G Cidea cell death inducing DFFA like effector a ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936626:230,372...246,893 JBrowse link
G Corin corin, serine peptidase ISO mRNA:decreased expression:left atrium, right atrium (rat)
mRNA:increased expression:heart (rat)
RGD PMID:15155264, PMID:15191894 RGD:1581217, RGD:1581218 NCBI chrNW_004936482:13,782,571...13,999,561 JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chrNW_004936740:885,855...888,854 JBrowse link
G Cryab crystallin alpha B ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:1560021, PMID:16483541, PMID:16793013, PMID:17116488, PMID:20171888, PMID:21920752, PMID:22106715, PMID:22995991, PMID:23194663, PMID:23299917, PMID:24033266, PMID:25208129, PMID:25741868, PMID:26694549, PMID:26961874, PMID:28492532 NCBI chrNW_004936612:2,532,851...2,536,473 JBrowse link
G Cs citrate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8922916 NCBI chrNW_004936646:676,926...704,988 JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11732872 NCBI chrNW_004936647:3,081,896...3,083,864 JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585077 NCBI chrNW_004936490:15,142,526...15,146,375 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO mRNA, protein:increased expression: paraventricular nucleus of hypothalamus RGD PMID:24036597 RGD:9491792 NCBI chrNW_004936473:28,508,726...28,535,640 JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chrNW_004936837:523,227...538,799 JBrowse link
G Dio3 iodothyronine deiodinase 3 ISO associated with Hypertrophy, Right Ventricular;mRNA, protein:increased expression:heart right ventricle RGD PMID:18259611 RGD:2303417 NCBI chrNW_004936604:5,241,877...5,243,910 JBrowse link
G Dmd dystrophin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:atrium: RGD PMID:23573917 RGD:9588286 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Dstn destrin, actin depolymerizing factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chrNW_004936485:2,504,492...2,537,507 JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO protein:increased expression:paraventricular nucleus RGD PMID:23832698 RGD:7257598 NCBI chrNW_004936668:451,846...484,841 JBrowse link
G Ece1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney:
associated with myocardial ischemia
RGD PMID:9595392, PMID:11145756, PMID:19596829 RGD:1580911, RGD:7243876, RGD:7244244 NCBI chrNW_004936474:7,034,134...7,083,005 JBrowse link
G Edn1 endothelin 1 severity
treatment
ISO protein:increased secretion:plasma (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart:
RGD
CTD
PMID:7967349, PMID:7969316, PMID:8149524, PMID:9861300, PMID:10199843, PMID:10973842, PMID:11136700, PMID:11707688, PMID:16360360, PMID:16762801 RGD:4144845, RGD:7244167, RGD:8661798 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Ednra endothelin receptor type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chrNW_004936535:1,950,117...2,005,786 JBrowse link
G Ednrb endothelin receptor type B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chrNW_004936511:3,446,864...3,478,434 JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936563:1,224,392...1,344,707 JBrowse link
G Endog endonuclease G ISO mRNa:decreased expression:heart: RGD PMID:17292393 RGD:9685393 NCBI chrNW_004936487:16,282,115...16,285,486 JBrowse link
G Eng endoglin treatment ISO protein:increased expression:heart left ventricle (rat) RGD PMID:20156938 RGD:7257540 NCBI chrNW_004936487:15,467,165...15,499,180 JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18443590 NCBI chrNW_004936675:350,357...392,919 JBrowse link
G Epo erythropoietin treatment ISO associated with Myocardial Infarction RGD PMID:20139114 RGD:10401073 NCBI chrNW_004936543:742,722...745,332 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:10421602 RGD:1580989 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO associated with Aortic Valve Stenosis;mRNA, protein:decreased expression:heart myocardium RGD PMID:10421602 RGD:1580989 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G Esrra estrogen related receptor alpha ISO protein:decreased expression:heart: RGD PMID:21825219 RGD:10401867 NCBI chrNW_004936599:4,898,534...4,922,758 JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 ISO DNA:deletion:introns, exon (human)
ClinVar Annotator: match by term: Congestive heart failure
RGD
ClinVar
PMID:15735644, PMID:25741868, PMID:28492532 RGD:1598455 NCBI chrNW_004936560:1,325,521...1,466,216 JBrowse link
G Fas Fas cell surface death receptor treatment ISO mRNA:splice variant:heart left ventricle (human) RGD PMID:9367848, PMID:29746994 RGD:13792577, RGD:8686420 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:29746994 RGD:13792577 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936594:5,591,785...5,609,886 JBrowse link
G Fbln5 fibulin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189163 NCBI chrNW_004936733:136,374...200,106 JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chrNW_004936482:16,126,608...16,194,729 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO associated with Shock, Septic RGD PMID:17637193 RGD:2302075 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:15623567 RGD:2293777 NCBI chrNW_004936488:4,384,710...4,388,118 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit ISO RGD PMID:15623567 RGD:2293777 NCBI chrNW_004936599:3,642,504...3,649,294 JBrowse link
G Foxc2 forkhead box C2 ISO RGD PMID:16952980 RGD:1582564 NCBI chrNW_004936641:2,236,224...2,238,501 JBrowse link
G Foxo1 forkhead box O1 ISO RGD PMID:16952980 RGD:1582564 NCBI chrNW_004936565:5,210,014...5,299,213 JBrowse link
G Foxp1 forkhead box P1 ISO RGD PMID:16952980 RGD:1582564 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G Foxp4 forkhead box P4 ISO RGD PMID:16952980 RGD:1582564 NCBI chrNW_004936476:18,314,108...18,346,149 JBrowse link
G Fth1 ferritin heavy chain 1 ISO protein:decreased expression:heart RGD PMID:18992754 RGD:2315110 NCBI chrNW_004936581:1,118,905...1,120,592 JBrowse link
G Fxyd1 FXYD domain containing ion transport regulator 1 ISO protein:increased serine phosphorylation:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chrNW_004936570:1,117,083...1,121,059 JBrowse link
G Gatm glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16820567 NCBI chrNW_004936471:8,017,611...8,032,703 JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:7608802 NCBI chrNW_004936469:16,906,658...16,916,045 JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chrNW_004936596:2,854,620...2,857,018 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:20572026 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Gpx4 glutathione peroxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936588:506,101...508,469 JBrowse link
G Grk1 G protein-coupled receptor kinase 1 ISO RGD PMID:12456492 RGD:1600002 NCBI chrNW_004936472:152,202...165,134 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment ISO mRNA:decreased expression:peripheral blood mononuclear cell (human)
CTD Direct Evidence: marker/mechanism
associated with Hypertrophy, Left Ventricular and Hypertension;protein:increased expression, increased activity:heart left ventricle, cytosol (rat)
RGD
CTD
PMID:9931137, PMID:11331748, PMID:26248277, PMID:26670611, PMID:29247373 RGD:11535540, RGD:13506830, RGD:1625790, RGD:737776 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Grk3 G protein-coupled receptor kinase 3 severity ISO mRNA:decreased expression:heart left ventricle (human) RGD PMID:22685168 RGD:13506835 NCBI chrNW_004936657:425,902...522,331 JBrowse link
G Grk5 G protein-coupled receptor kinase 5 severity ISO mRNA:decreased expression:heart left ventricle (human)
mRNA:decreased expression:peripheral blood mononuclear cell (human)
RGD PMID:22685168, PMID:26248277 RGD:11535540, RGD:13506835 NCBI chrNW_004936486:8,720,036...8,830,472 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901358 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:serum, urine RGD PMID:21080339 RGD:11041621 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chrNW_004936516:4,692,926...4,695,625 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:heart right ventricle (rat)
CTD
RGD
PMID:15732037, PMID:17582388 RGD:9068910 NCBI chrNW_004936495:5,770,988...5,816,157 JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO protein:decreased expression:heart RGD PMID:23708738, PMID:24204700 RGD:10402070, RGD:10402081 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22352330, PMID:23592614 RGD:10755584 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Hrh2 histamine receptor H2 susceptibility ISO RGD PMID:24655024 RGD:9685523 NCBI chrNW_004936609:624,446...664,049 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO protein:altered localization:heart left ventricle (rat) RGD PMID:24285117 RGD:10402754 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17481944 NCBI chrNW_004936543:2,110,351...2,111,896 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO mRNA:increased expression:heart left ventricle RGD PMID:16002744 RGD:1600503 NCBI chrNW_004936565:335,238...394,683 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO mRNA:increased expression:left ventricle cardiac muscle (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17936780, PMID:19023134 RGD:9698457 NCBI chrNW_004936525:5,711,894...5,729,074 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:3091246, PMID:20938210 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Igf1 insulin like growth factor 1 ISO RGD PMID:12835956 RGD:1598415 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il10 interleukin 10 disease_progression
treatment
ISO RGD PMID:16461369, PMID:23778495, PMID:28939262 RGD:14975271, RGD:1598465, RGD:7365020 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il17a interleukin 17A ISO protein:increased expression:heart RGD PMID:19527710, PMID:19909738 RGD:2325816, RGD:4831836 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15135663 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il6r interleukin 6 receptor ISO protein:increased expression:paraventricular hypothalamic nucleus RGD PMID:17095650 RGD:1625433 NCBI chrNW_004936580:4,055,438...4,081,876 JBrowse link
G Ins insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15628829 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884376 NCBI chrNW_004936574:1,465,981...1,495,717 JBrowse link
G Kat8 lysine acetyltransferase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27768893 NCBI chrNW_004936501:13,475,676...13,487,617 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO associated with Myocardial Infarction (RDO:0006167); mRNA:increased expression:heart left ventricle, septum
mRNA:increased expression:endocardium of right ventricle:
RGD PMID:16497176, PMID:17384445 RGD:12910696, RGD:1642301 NCBI chrNW_004936500:7,998,464...8,007,848 JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 ISO associated with Hypertension, Pulmonary:mRNA:decreased expression:heart right ventricle (rat) RGD PMID:25016242 RGD:9831185 NCBI chrNW_004936628:3,155,261...3,284,375 JBrowse link
G Kdm2a lysine demethylase 2A ISO protein:altered localization:promoter (mouse) RGD PMID:25181347 RGD:9588275 NCBI chrNW_004936599:2,466,427...2,576,623 JBrowse link
G Lep leptin ISO RGD PMID:18006469 RGD:5128823 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G Lepr leptin receptor ISO protein:increased phosphorylation:heart RGD PMID:18006469 RGD:5128823 NCBI chrNW_004936591:5,771,371...5,846,177 JBrowse link
G Lgals3 galectin 3 ISO RGD PMID:15520318 RGD:9685214 NCBI chrNW_004936697:20,861...38,568 JBrowse link
G Lif LIF interleukin 6 family cytokine ISO RGD PMID:20051627 RGD:2326058 NCBI chrNW_004936904:410,043...413,256 JBrowse link
G LOC101966992 cytochrome b-245 heavy chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936502:4,631,750...4,676,686 JBrowse link
G LOC101968921 angiotensin-converting enzyme treatment ISO associated with Hypertension
CTD Direct Evidence: marker/mechanism
associated with Myocardial Infarction
RGD
CTD
PMID:15894569, PMID:18586661, PMID:19620082, PMID:22123369 RGD:12859272, RGD:2325224, RGD:6893472 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G LOC101972165 myosin-7 treatment ISO associated with Myocardial Infarction RGD PMID:18088389 RGD:12792974 NCBI chrNW_004936722:967,443...991,530 JBrowse link
G LOC101976500 haptoglobin treatment ISO RGD PMID:23494325 RGD:11041812 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chrNW_004936588:4,882,191...4,891,807 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO protein:increased activity:heart: RGD PMID:17562954 RGD:10412331 NCBI chrNW_004936560:3,988,696...4,197,953 JBrowse link
G Mdh2 malate dehydrogenase 2 ISO RGD PMID:16786185 RGD:1582470 NCBI chrNW_004936543:2,194,074...2,208,626 JBrowse link
G Mme membrane metalloendopeptidase ISO RGD PMID:12383878 RGD:13801043 NCBI chrNW_004936519:2,513,896...2,595,896 JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:12892382, PMID:21866669 RGD:1582539, RGD:7207282 NCBI chrNW_004936551:5,167,909...5,175,149 JBrowse link
G Mmp13 matrix metallopeptidase 13 disease_progression ISO protein:increased expression:left ventricle (rat)
associated with Hypertension
RGD PMID:10773234, PMID:10773235 RGD:1582587, RGD:2290467 NCBI chrNW_004936551:5,040,084...5,050,384 JBrowse link
G Mmp14 matrix metallopeptidase 14 disease_progression ISO protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chrNW_004936722:1,447,189...1,457,632 JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO mRNA:increased expression:heart left ventricle
protein:increased expression:heart left ventricle, plasma
RGD PMID:10773234, PMID:16169329, PMID:20606426 RGD:1582574, RGD:2290467, RGD:8694112 NCBI chrNW_004936475:7,801,356...7,825,831 JBrowse link
G Mmp8 matrix metallopeptidase 8 disease_progression ISO protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chrNW_004936551:5,228,950...5,238,948 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:heart left ventricle, plasma
associated with Hypertension, Pulmonary; protein:increased expression:heart
RGD PMID:11342481, PMID:16952784, PMID:17913382, PMID:20606426 RGD:1582647, RGD:5130174, RGD:7207137, RGD:8694112 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Mstn myostatin ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:myocardium
CTD
RGD
PMID:16968467 RGD:2303554 NCBI chrNW_004936506:7,988,879...7,996,260 JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO mRNA, protein:increased expression:heart RGD PMID:20861467 RGD:10003169 NCBI chrNW_004936474:158,376...282,310 JBrowse link
G Myod1 myogenic differentiation 1 treatment ISO associated with Aortic Valve Stenosis RGD PMID:20060348 RGD:9686081 NCBI chrNW_004936528:1,407,187...1,409,683 JBrowse link
G Myot myotilin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936597:4,830,111...4,847,409 JBrowse link
G Mypn myopalladin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:22286171, PMID:23299917, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chrNW_004936521:10,050,638...10,142,395 JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO mRNA, protein:increased expression:heart RGD PMID:19853610 RGD:2325979 NCBI chrNW_004936612:1,262,557...1,556,281 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:28373008, PMID:29373037 RGD:26923905 NCBI chrNW_004936509:6,589,967...6,621,171 JBrowse link
G Ngfr nerve growth factor receptor ISO associated with Myocardial Infarction ;mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chrNW_004936490:12,038,500...12,057,257 JBrowse link
G Nisch nischarin ISO RGD PMID:12021582 RGD:1581128 NCBI chrNW_004936473:3,295,515...3,331,324 JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO protein:increased expression:heart, left ventricle, sarcolemma (human) RGD PMID:11121795 RGD:5132888 NCBI chrNW_004936490:10,634,788...10,640,182 JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:15466641, PMID:23832698 RGD:1581144, RGD:7257598 NCBI chrNW_004936558:5,162,471...5,302,488 JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19168511 NCBI chrNW_004936538:4,052,277...4,097,051 JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19168511, PMID:20304815, PMID:29351461 RGD:13504746 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Nox1 NADPH oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936584:6,023,960...6,040,041 JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936736:230,465...394,859 JBrowse link
G Nppa natriuretic peptide A treatment
severity
ISO protein:increased expression:plasma
mRNA,protein:increased expression:heart,plasma
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:1647690, PMID:2143809, PMID:8112904, PMID:11136700, PMID:11421854, PMID:16101196, PMID:23566312, PMID:23931972 RGD:1580139, RGD:1580140, RGD:7247714, RGD:7297049 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Nppb natriuretic peptide B severity ISO protein:increased expression:plasma
associated with Diabetes Mellitus;protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA,protein:increased expression:heart,plasma
RGD
CTD
PMID:1831369, PMID:2143809, PMID:11136700, PMID:11279304, PMID:11421854, PMID:12628948, PMID:15732037, PMID:15860969, PMID:16101196, PMID:16333235, PMID:16360360, PMID:16762801, PMID:16777915, PMID:17257273, PMID:19650993, PMID:24535859, PMID:29959987 RGD:1580139, RGD:1580140, RGD:1642196, RGD:7247316 NCBI chrNW_004936474:683,325...684,662 JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO CTD Direct Evidence: marker/mechanism
associated with Hypertension
protein:decreased expression:kidney
CTD
RGD
PMID:9405681, PMID:17264312, PMID:20881240 RGD:7247730, RGD:737701 NCBI chrNW_004936580:3,479,858...3,496,896 JBrowse link
G Nptxr neuronal pentraxin receptor ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chrNW_004936492:2,546,774...2,568,206 JBrowse link
G Npy neuropeptide Y ISO RGD PMID:17804485 RGD:7175103 NCBI chrNW_004936478:1,289,437...1,296,819 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 treatment ISO RGD PMID:21737535 RGD:7174712 NCBI chrNW_004936504:10,960,069...11,056,834 JBrowse link
G Nr3c2 nuclear receptor subfamily 3 group C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15722665, PMID:21321305 NCBI chrNW_004936535:1,139,687...1,467,469 JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19801490 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chrNW_004936505:7,886,327...7,966,969 JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase ISO protein:increased expression:heart left ventricle (rat) RGD PMID:22128088 RGD:9590202 NCBI chrNW_004936762:99,335...137,833 JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chrNW_004936902:405,536...416,393 JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase ISO protein:decreased expression:heart RGD PMID:19493956 RGD:7800717 NCBI chrNW_004936711:1,027,531...1,113,796 JBrowse link
G P2rx4 purinergic receptor P2X 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chrNW_004936558:3,062,279...3,077,493 JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chrNW_004936533:2,684,826...2,764,682 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 treatment ISO associated with Hypertension RGD PMID:19443425 RGD:11074236 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936530:361,872...367,005 JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO protein:decreased expression:heart: RGD PMID:23647599 RGD:10448278 NCBI chrNW_004936489:2,677,740...2,720,387 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chrNW_004936482:16,804,129...16,853,539 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19429709 NCBI chrNW_004936694:1,444,819...1,487,628 JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936668:2,316,661...2,323,015 JBrowse link
G Pgf placental growth factor ISO RGD PMID:19327525 RGD:6483590 NCBI chrNW_004936488:4,098,187...4,111,108 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12963636, PMID:15936620 RGD:6482699 NCBI chrNW_004936479:17,084,006...17,112,264 JBrowse link
G Pkp2 plakophilin 2 ISO ClinVar Annotator: match by term: CHF ClinVar PMID:22035158, PMID:25445213, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chrNW_004936607:3,458,406...3,530,066 JBrowse link
G Pla2g7 phospholipase A2 group VII ISO RGD PMID:16952920 RGD:6482778 NCBI chrNW_004936476:13,609,847...13,646,174 JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chrNW_004936785:476,200...503,371 JBrowse link
G Plcd1 phospholipase C delta 1 ISO RGD PMID:11181012 RGD:2300431 NCBI chrNW_004936473:27,364,404...27,387,337 JBrowse link
G Pld2 phospholipase D2 ISO protein:increased expression:heart left ventricle RGD PMID:15601581 RGD:2299908 NCBI chrNW_004936677:2,870,664...2,883,545 JBrowse link
G Pln phospholamban treatment ISO associated with Myocardial Infarction
associated with Hypertension
RGD PMID:22947202, PMID:22970977 RGD:7327181, RGD:7327182 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:3026683, PMID:8277081 NCBI chrNW_004936493:7,060,747...7,065,276 JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936585:4,954,871...4,979,560 JBrowse link
G Postn periostin treatment ISO mRNA:increased expression:heart RGD PMID:15381649, PMID:16414453 RGD:10040951, RGD:10040999 NCBI chrNW_004936472:31,644,778...31,677,572 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha onset ISO mRNA:decreased expression:heart (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19808358, PMID:22503866, PMID:23297372, PMID:23342071 RGD:7241838, RGD:7241843 NCBI chrNW_004936477:4,881,230...5,488,208 JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:12024026 RGD:737728 NCBI chrNW_004936599:2,345,982...2,348,494 JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO protein:increased expression:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chrNW_004936558:3,631,794...3,651,754 JBrowse link
G Ppp1r1a protein phosphatase 1 regulatory inhibitor subunit 1A ISO CTD Direct Evidence: therapeutic CTD PMID:20071777 NCBI chrNW_004936512:11,765,769...11,775,573 JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO mRNA:increased expression:vastus lateralis muscle (human) RGD PMID:14567976 RGD:8693707 NCBI chrNW_004936647:1,031,118...1,055,961 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chrNW_004936659:2,750,015...2,765,914 JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Congestive heart failure
ClinVar Annotator: match by term: Heart failure
ClinVar PMID:21409595, PMID:24033266, PMID:25741868, PMID:27532257, PMID:28492532 NCBI chrNW_004936527:6,907,723...7,168,222 JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chrNW_004936529:528,138...601,078 JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936479:16,894,068...16,988,879 JBrowse link
G Prkca protein kinase C alpha ISO protein:increased expression, increased phosphorylation:heart left ventricle RGD PMID:17556659 RGD:2292480 NCBI chrNW_004936541:6,231,604...6,488,201 JBrowse link
G Prkcb protein kinase C beta ISO associated with hypertension RGD PMID:12392998 RGD:1625516 NCBI chrNW_004936501:8,410,273...8,729,238 JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18926768 NCBI chrNW_004936552:7,204,298...7,212,632 JBrowse link
G Psen1 presenilin 1 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:17186461, PMID:25741868, PMID:28492532 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17162251, PMID:21939825 RGD:7242422 NCBI chrNW_004936528:5,081,569...5,084,030 JBrowse link
G Ptprf protein tyrosine phosphatase receptor type F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chrNW_004936474:24,908,103...24,984,678 JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12642504, PMID:16155095 RGD:1581295 NCBI chrNW_004936750:107,689...122,679 JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO associated with Hypertension RGD PMID:12623952 RGD:704370 NCBI chrNW_004936490:17,479,899...17,481,788 JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO mRNA, protein:increased expression:left ventricle myocardium (human) RGD PMID:18323524 RGD:9835356 NCBI chrNW_004936512:5,636,197...5,659,606 JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936486:1,472,170...1,652,314 JBrowse link
G Rbp4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936601:1,401,215...1,410,195 JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:1647690, PMID:7034517, PMID:20811386 NCBI chrNW_004936567:598,044...607,628 JBrowse link
G Retn resistin ISO CTD Direct Evidence: marker/mechanism
associated with Coronary Disease
CTD
RGD
PMID:22240747, PMID:26670611 RGD:7207075 NCBI chrNW_004936588:4,705,295...4,706,653 JBrowse link
G Rnls renalase, FAD dependent amine oxidase ISO RGD PMID:21297953 RGD:7327162 NCBI chrNW_004936735:659,826...1,048,135 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator ISO mRNA, protein:decreased expression:heart RGD PMID:18056528 RGD:2311701 NCBI chrNW_004936475:17,173,170...17,176,446 JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Congestive heart failure RGD
ClinVar
PMID:16483256, PMID:25741868 RGD:1599251 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO mRNA:decreased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 ISO mRNA:increased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chrNW_004936512:9,164,310...9,281,795 JBrowse link
G Selp selectin P ISO RGD PMID:19193626 RGD:2312309 NCBI chrNW_004936481:17,076,660...17,112,501 JBrowse link
G Serpine1 serpin family E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24535859 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Sirt3 sirtuin 3 ISO protein:decreased expression:heart left ventricle RGD PMID:22155497 RGD:9586040 NCBI chrNW_004936888:63,131...78,536 JBrowse link
G Slc2a4 solute carrier family 2 member 4 severity ISO protein:decreased expression:skeletal muscle RGD PMID:18778861 RGD:2313624 NCBI chrNW_004936595:567,267...574,051 JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO DNA:repeat:promoter (human) RGD PMID:17307423 RGD:4889438 NCBI chrNW_004936538:6,205,268...6,239,062 JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO protein:increased expression:cardiac muscle cell RGD PMID:17536604 RGD:1642720 NCBI chrNW_004936508:10,894,918...11,256,084 JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18776042, PMID:19027022 RGD:6771337 NCBI chrNW_004936474:11,460,266...11,517,420 JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chrNW_004936500:10,345,154...10,352,873 JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16105639, PMID:16155095, PMID:20304815, PMID:21195081, PMID:21284947 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
G Srf serum response factor ISO mRNA, protein:splice variant:heart RGD PMID:11893590 RGD:1581426 NCBI chrNW_004936476:16,779,941...16,789,499 JBrowse link
G Sri sorcin ISO associated with Hypertension
protein:decreased expression:cardiac muscle cell
RGD PMID:12754254, PMID:20945956 RGD:7327198, RGD:7327200 NCBI chrNW_004936763:715,884...728,548 JBrowse link
G Tbx20 T-box transcription factor 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chrNW_004936478:10,887,900...10,939,510 JBrowse link
G Th tyrosine hydroxylase ISO protein:increased expression:paraventricular thalamic nucleus (rat) RGD PMID:7715703, PMID:21287352 RGD:5128674, RGD:737737 NCBI chrNW_004936794:478,651...486,887 JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chrNW_004936502:13,345,936...13,350,170 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chrNW_004936594:3,232,433...3,244,241 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO protein:decreased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chrNW_004936602:1,488,993...1,496,108 JBrowse link
G Tlr2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chrNW_004936576:522,234...531,660 JBrowse link
G Tnf tumor necrosis factor treatment
severity
ISO CTD Direct Evidence: marker/mechanism
associated with Myocardial Infarction;
CTD
RGD
PMID:11100001, PMID:11668085, PMID:15135663, PMID:15210453, PMID:15231041, PMID:17337591, PMID:18034274, PMID:28939262, PMID:29959987 RGD:14975271, RGD:1580213, RGD:7401241, RGD:7401242 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b ISO mRNA, protein:incereased expression:myocardium RGD PMID:15883214 RGD:1624176 NCBI chrNW_004936470:27,571,263...27,598,725 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chrNW_004936709:1,407,327...1,421,448 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21135513 RGD:5131262 NCBI chrNW_004936474:908,414...935,765 JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12322705, PMID:17698733 NCBI chrNW_004936567:3,052,167...3,069,077 JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 ISO protein:increased serine phosphorylation:heart, mitochondrion
mRNA:decreased expression:heart
RGD PMID:24395194, PMID:25022898 RGD:13464131, RGD:13464132 NCBI chrNW_004936630:2,906,573...2,938,837 JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Heart failure
ClinVar Annotator: match by term: CHF
ClinVar Annotator: match by term: Congestive heart failure
ClinVar PMID:15802564, PMID:23396983, PMID:23486992, PMID:23861362, PMID:24033266, PMID:24055113, PMID:24231549, PMID:24271327, PMID:24503780, PMID:24569025, PMID:24578547, PMID:25589632, PMID:25741868, PMID:26272908, PMID:26383259, PMID:26467025, PMID:26498160, PMID:26516846, PMID:27194543, PMID:27843123, PMID:28256728, PMID:28492532, PMID:29361395, PMID:30311386 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link
G Ttr transthyretin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:1355416, PMID:1850190, PMID:1997217, PMID:2174830, PMID:2590199, PMID:6736244, PMID:7923855, PMID:8102146, PMID:9090525, PMID:14640030, PMID:15185492, PMID:19428025, PMID:22332999, PMID:24033266, PMID:24955979, PMID:25741868, PMID:28492532 NCBI chrNW_004936682:1,628,489...1,635,495 JBrowse link
G Tubb tubulin beta class I ISO CTD Direct Evidence: marker/mechanism CTD PMID:16155095 NCBI chrNW_004936837:380,880...384,752 JBrowse link
G Ucn urocortin ISO protein:increased secretion:plasma (human) RGD PMID:19808377 RGD:5490589 NCBI chrNW_004936493:5,258,574...5,260,692 JBrowse link
G Ucn2 urocortin 2 ISO CTD Direct Evidence: therapeutic
mRNA, protein:increased expression:myocardium (human)
CTD
RGD
PMID:12076554, PMID:16330704 RGD:5508210 NCBI chrNW_004936529:347,411...348,040 JBrowse link
G Ucp1 uncoupling protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chrNW_004936535:7,258,146...7,265,475 JBrowse link
G Ucp2 uncoupling protein 2 ISO protein:decreased expression:heart, mitochondria RGD PMID:20193183, PMID:20809120 RGD:7204424, RGD:7204426 NCBI chrNW_004936498:3,059,700...3,066,112 JBrowse link
G Ucp3 uncoupling protein 3 ISO protein:decreased expression:heart, mitochondria RGD PMID:20809120 RGD:7204424 NCBI chrNW_004936498:3,082,575...3,095,739 JBrowse link
G Uts2 urotensin 2 severity ISO protein:increased expression:plasma RGD PMID:12791592, PMID:16364499 RGD:1580809, RGD:2306804 NCBI chrNW_004936623:2,339,259...2,345,717 JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:24033266, PMID:28492532 NCBI chrNW_004936521:5,051,077...5,163,036 JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15732037, PMID:15880336 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chrNW_004936709:1,578,137...1,741,877 JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19933411 NCBI chrNW_004936493:1,762,814...1,824,501 JBrowse link
G Yy1 YY1 transcription factor ISO RGD PMID:12754214 RGD:1580831 NCBI chrNW_004936604:3,911,407...3,945,405 JBrowse link
Alcohol-Induced Sudden Cardiac Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 inorganic pyrophosphatase 2 ISO OMIM NCBI chrNW_004936752:279,541...352,201 JBrowse link
cardiac arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:26010685 RGD:12791997 NCBI chrNW_004936528:1,608,782...1,682,873 JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:23861362, PMID:28492532 NCBI chrNW_004936621:2,247,082...2,374,407 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:20363892 RGD:5509101 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Ank2 ankyrin 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:28600387 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:21383000, PMID:22840528, PMID:25527503, PMID:28492532 NCBI chrNW_004936734:577,656...1,027,412 JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:30311386 NCBI chrNW_004936520:8,951,994...9,164,039 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:hippocampus (rat) RGD PMID:19756023 RGD:4889980 NCBI chrNW_004936490:253,279...259,947 JBrowse link
G Cep85l centrosomal protein 85 like ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chrNW_004936658:1,351,968...1,490,861 JBrowse link
G Dpp6 dipeptidyl peptidase like 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chrNW_004936527:8,574,455...9,423,445 JBrowse link
G Dsc2 desmocollin 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:18678517, PMID:23861362, PMID:24033266, PMID:24704780, PMID:25637381, PMID:25741868, PMID:27153395, PMID:28492532 NCBI chrNW_004936682:2,057,331...2,091,034 JBrowse link
G Dsg2 desmoglein 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:20400443, PMID:23861362, PMID:24070718, PMID:25741868, PMID:28492532, PMID:28600387 NCBI chrNW_004936682:1,676,301...1,725,132 JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:21606390, PMID:25525159, PMID:25741868, PMID:28492532 NCBI chrNW_004936534:5,029,008...5,076,467 JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO RGD PMID:9522364 RGD:13208524 NCBI chrNW_004936668:451,846...484,841 JBrowse link
G Ep300 E1A binding protein p300 ISO associated with Diabetes Mellitus; mRNA:increased expression:blood (human) RGD PMID:19577077 RGD:2312286 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:17728042 RGD:5688386 NCBI chrNW_004936675:350,357...392,919 JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:30311386 NCBI chrNW_004936473:22,649,107...22,774,719 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:9806674 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il18 interleukin 18 ISO RGD PMID:18679114 RGD:4889454 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Ins insulin ISO CTD Direct Evidence: therapeutic CTD PMID:17449947 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 ISO protein:increased expression:cerebellum (rat) RGD PMID:21859719 RGD:6480675 NCBI chrNW_004936577:3,896,455...4,198,396 JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chrNW_004936548:5,125,583...5,132,490 JBrowse link
G Mybpc3 myosin binding protein C3 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:14563344, PMID:15519027, PMID:16352453, PMID:20624503, PMID:22361390, PMID:23140321, PMID:23299917, PMID:23785128, PMID:24033266, PMID:24503780, PMID:24510615, PMID:25163546, PMID:25741868, PMID:28492532 NCBI chrNW_004936562:1,871,194...1,890,092 JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chrNW_004936672:1,351,053...1,481,954 JBrowse link
G Nsun6 NOP2/Sun RNA methyltransferase 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:30311386 NCBI chrNW_004936520:8,909,509...8,950,960 JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chrNW_004936527:6,907,723...7,168,222 JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:22004663, PMID:24033266, PMID:24503780, PMID:25637381, PMID:25741868, PMID:27896284, PMID:28492532 NCBI chrNW_004936486:1,472,170...1,652,314 JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12354768, PMID:12820704, PMID:15466642, PMID:15840476, PMID:16540748, PMID:17161064, PMID:17210839, PMID:18071069, PMID:18452873, PMID:19412328, PMID:20403459, PMID:20875080, PMID:22378279, PMID:22581653, PMID:23008441, PMID:23098067, PMID:24033266, PMID:24653702, PMID:25741868, PMID:26209461, PMID:26467025, PMID:26749013, PMID:27287068, PMID:28265756, PMID:28492532, PMID:28781330, PMID:29032884 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
G Slmap sarcolemma associated protein ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chrNW_004936473:8,057,236...8,208,564 JBrowse link
G Sod1 superoxide dismutase 1 ISO RGD PMID:15843790 RGD:1581221 NCBI chrNW_004936500:10,345,154...10,352,873 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:9806674, PMID:18679114 RGD:4889454 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 treatment ISO ClinVar Annotator: match by term: Cardiac arrest RGD
ClinVar
PMID:26010685, PMID:28492532 RGD:12791997 NCBI chrNW_004936664:3,093,258...3,124,473 JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:19608031, PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004936521:5,051,077...5,163,036 JBrowse link
Cardiac Edema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:22865611 NCBI chrNW_004936478:7,146,997...7,160,369 JBrowse link
G Ift122 intraflagellar transport 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20493458 NCBI chrNW_004936602:908,034...956,634 JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23533172 NCBI chrNW_004936474:284,630...293,090 JBrowse link
Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO protein:increased expression:kidney tubule: RGD PMID:22367506, PMID:23220287 RGD:7245477, RGD:7245950 NCBI chrNW_004936515:6,030,402...6,051,161 JBrowse link
Cor pulmonale term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO RGD PMID:21450080 RGD:6767563 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:20669672 RGD:4143386 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:20669672 RGD:4143386 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
diastolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1d adrenoceptor alpha 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936485:14,514,395...14,538,389 JBrowse link
G Akip1 A-kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936528:9,141,824...9,151,224 JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936744:776,030...781,710 JBrowse link
G Apln apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936479:1,889,930...1,899,811 JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936485:14,897,050...14,914,034 JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936472:2,416,043...2,543,561 JBrowse link
G Col6a1 collagen type VI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936778:515,600...530,828 JBrowse link
G Col8a1 collagen type VIII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936630:3,443,085...3,590,430 JBrowse link
G Creg1 cellular repressor of E1A stimulated genes 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936481:18,523,022...18,531,227 JBrowse link
G Cyrib CYFIP related Rac1 interactor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936470:18,665,898...18,803,864 JBrowse link
G Elk3 ETS transcription factor ELK3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936507:12,244,163...12,307,621 JBrowse link
G Epn3 epsin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936490:11,174,552...11,184,516 JBrowse link
G Fhl1 four and a half LIM domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936513:11,025,753...11,064,312 JBrowse link
G Fibin fin bud initiation factor homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936540:6,157,130...6,158,321 JBrowse link
G Fxyd3 FXYD domain containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936570:1,132,185...1,137,676 JBrowse link
G Hamp hepcidin antimicrobial peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936659:1,320,169...1,340,137 JBrowse link
G Klf9 Kruppel like factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936503:6,517,748...6,553,532 JBrowse link
G LOC101972165 myosin-7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936722:967,443...991,530 JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936501:11,998,064...11,999,431 JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936755:444,264...456,071 JBrowse link
G Plxnd1 plexin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936602:848,130...882,195 JBrowse link
G Ptp4a2 protein tyrosine phosphatase 4A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936474:14,993,741...15,005,219 JBrowse link
G Ptpn3 protein tyrosine phosphatase non-receptor type 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936559:3,436,114...3,547,316 JBrowse link
G Sfrp1 secreted frizzled related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936785:1,276,478...1,320,397 JBrowse link
G Sipa1l1 signal induced proliferation associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936488:819,503...1,175,043 JBrowse link
G Trdn triadin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936802:389,653...637,372 JBrowse link
G Wdr45 WD repeat domain 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936721:975,113...981,149 JBrowse link
G Znf532 zinc finger protein 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chrNW_004936497:5,648,294...5,755,948 JBrowse link
Neonatal Pulmonary Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cps1 carbamoyl-phosphate synthase 1 susceptibility ISO ClinVar Annotator: match by term: Pulmonary hypertension, neonatal, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11407344, PMID:14718356, PMID:15465784, PMID:16708072, PMID:20154341, PMID:21767969 NCBI chrNW_004936586:5,739,038...5,850,317 JBrowse link
Paroxysmal Dyspnea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:21388992 RGD:5129099 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO ClinVar Annotator: match by term: Asthma, nocturnal, susceptibility to ClinVar PMID:7706471, PMID:9399946, PMID:9399966, PMID:9522789, PMID:11739457, PMID:14557466, PMID:15500895, PMID:15867853, PMID:16596417, PMID:28492532 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
primary pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:9245985, PMID:12700602, PMID:14684682, PMID:15024723, PMID:15879500, PMID:15880681, PMID:16429404, PMID:16470787, PMID:16540754, PMID:16705692, PMID:18159113, PMID:19555857, PMID:20414677, PMID:20501893, PMID:21158752, PMID:22632830, PMID:23298310, PMID:23722869, PMID:24753439, PMID:25741868, PMID:26387786, PMID:27316748, PMID:28492532, PMID:29449337, PMID:32581362 NCBI chrNW_004936512:9,364,551...9,379,131 JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Primary pulmonary hypertension
ClinVar Annotator: match by term: Pulmonary hypertension, primary, dexfenfluramine-associated
ClinVar Annotator: match by term: Pulmonary hypertension, primary, fenfluramine-associated
ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension
ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia
CTD
ClinVar
PMID:3291115, PMID:10903931, PMID:10973254, PMID:11015450, PMID:11115378, PMID:11502704, PMID:12045205, PMID:12139571, PMID:12358323, PMID:12446270, PMID:12821254, PMID:14516151, PMID:14583445, PMID:14985116, PMID:15055271, PMID:15059534, PMID:15146475, PMID:15170098, PMID:15358693, PMID:15591269, PMID:15687131, PMID:15775752, PMID:15965979, PMID:16429395, PMID:16429403, PMID:16717148, PMID:16728714, PMID:18159113, PMID:18221724, PMID:18356561, PMID:18364108, PMID:18386374, PMID:18503968, PMID:18792970, PMID:19206171, PMID:19223935, PMID:19324947, PMID:19555857, PMID:19844076, PMID:20002458, PMID:20095988, PMID:20096498, PMID:20496075, PMID:20534176, PMID:21070126, PMID:21228398, PMID:21737554, PMID:21801371, PMID:22632830, PMID:22995991, PMID:23139147, PMID:23298310, PMID:23579436, PMID:23592887, PMID:23675998, PMID:24033266, PMID:24591673, PMID:24853021, PMID:24936649, PMID:25326637, PMID:25429696, PMID:25460361, PMID:25612240, PMID:25688877, PMID:25741868, PMID:25917481, PMID:26387786, PMID:26820968, PMID:27453251, PMID:27630060, PMID:27884767, PMID:28388887, PMID:28492532, PMID:28507310, PMID:29631995, PMID:29650961, PMID:29743074, PMID:29843651, PMID:30029678, PMID:30311386, PMID:30578397, PMID:32581362 NCBI chrNW_004936726:1,543,263...1,711,422 JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Eng endoglin ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:18498373, PMID:23298310, PMID:24033266, PMID:25741868, PMID:26167679, PMID:26387786, PMID:28492532, PMID:30029678 NCBI chrNW_004936487:15,467,165...15,499,180 JBrowse link
G Foxf1 forkhead box F1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:19500772, PMID:19592680, PMID:19812545, PMID:20425831, PMID:22766610, PMID:23034409, PMID:23074687, PMID:23335808, PMID:23505205, PMID:23943206, PMID:24033266, PMID:24842713, PMID:26462560 NCBI chrNW_004943883:4...1,756 JBrowse link
G Hdac1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chrNW_004936474:15,320,635...15,351,418 JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chrNW_004936745:1,730,743...1,942,071 JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chrNW_004936541:561,721...598,915 JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO protein:decreased expression:lung, wall of arteriole (human) RGD PMID:20522807 RGD:9686087 NCBI chrNW_004936485:18,610,721...18,611,889 JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Primary pulmonary hypertension
CTD
ClinVar
PMID:23883380 NCBI chrNW_004936493:5,767,779...5,772,043 JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:23579436, PMID:26387786 NCBI chrNW_004936726:1,457,038...1,487,374 JBrowse link
G Smad1 SMAD family member 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:21898662, PMID:26387786 NCBI chrNW_004936535:3,582,512...3,626,312 JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:21898662, PMID:24728327, PMID:25502805, PMID:25741868, PMID:26387786, PMID:28492532 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
G Smad9 SMAD family member 9 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Primary pulmonary hypertension
CTD
ClinVar
NCBI chrNW_004936472:30,980,850...31,050,138 JBrowse link
G Tbx4 T-box transcription factor 4 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:25741868, PMID:31151956 NCBI chrNW_004936490:2,823,531...2,853,282 JBrowse link
Primary Pulmonary Hypertension, 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 ISO OMIM NCBI chrNW_004936726:1,543,263...1,711,422 JBrowse link
Primary Pulmonary Hypertension, 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad9 SMAD family member 9 ISO OMIM NCBI chrNW_004936472:30,980,850...31,050,138 JBrowse link
Primary Pulmonary Hypertension, 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 3 ClinVar PMID:25741868 NCBI chrNW_004936687:2,346,601...2,595,283 JBrowse link
G Cav1 caveolin 1 ISO OMIM NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
Primary Pulmonary Hypertension, 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium two pore domain channel subfamily K member 3 ISO OMIM NCBI chrNW_004936493:5,767,779...5,772,043 JBrowse link
Sudden Cardiac Death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long chain family member 3 disease_progression ISO RGD PMID:22661490 RGD:13831296 NCBI chrNW_004936569:4,774,602...4,842,906 JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chrNW_004936744:249,673...253,040 JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362, PMID:25741868, PMID:28492532 NCBI chrNW_004936621:2,247,082...2,374,407 JBrowse link
G Ank2 ankyrin 2 ISO ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
RGD
ClinVar
PMID:12571597, PMID:25741868, PMID:28492532 RGD:734572 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Apob apolipoprotein B ISO RGD PMID:17045270 RGD:1601197 NCBI chrNW_004936493:10,509,118...10,549,144 JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chrNW_004936606:2,168,104...2,867,560 JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:30311386 NCBI chrNW_004936473:4,164,633...4,479,866 JBrowse link
G Cep85l centrosomal protein 85 like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chrNW_004936658:1,351,968...1,490,861 JBrowse link
G Dpp6 dipeptidyl peptidase like 6 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chrNW_004936527:8,574,455...9,423,445 JBrowse link
G Dsp desmoplakin ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:20435227, PMID:25741868 NCBI chrNW_004936534:5,029,008...5,076,467 JBrowse link
G Dtna dystrobrevin alpha ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:30311386 NCBI chrNW_004936517:10,105,767...10,357,672 JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362, PMID:27930701, PMID:28492532 NCBI chrNW_004936473:22,649,107...22,774,719 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:21615589, PMID:23623143, PMID:23861362, PMID:24033266, PMID:24569893, PMID:25145517, PMID:25467552, PMID:25642760, PMID:26467025, PMID:28492532 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Itgb3 integrin subunit beta 3 ISO associated with arteriosclerosis; DNA:polymorphism:exon RGD PMID:20846430 RGD:5128476 NCBI chrNW_004936541:2,822,789...2,871,069 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar PMID:18508782, PMID:19716085, PMID:22581653, PMID:25417810, PMID:25741868, PMID:26704558 NCBI chrNW_004936527:6,380,222...6,412,390 JBrowse link
G Kng1 kininogen 1 susceptibility ISO DNA:SNPs: : RGD PMID:19716087 RGD:10411885 NCBI chrNW_004936578:3,255,335...3,281,296 JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15996213 NCBI chrNW_004936580:5,374,208...5,395,442 JBrowse link
G LOC101972165 myosin-7 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chrNW_004936722:967,443...991,530 JBrowse link
G Mybpc3 myosin binding protein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20435227 NCBI chrNW_004936562:1,871,194...1,890,092 JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24033266, PMID:28492532 NCBI chrNW_004936672:1,351,053...1,481,954 JBrowse link
G Nebl nebulette ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chrNW_004936520:6,658,555...6,992,643 JBrowse link
G Pkp2 plakophilin 2 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868, PMID:27532257, PMID:28492532, PMID:30311386 NCBI chrNW_004936607:3,458,406...3,530,066 JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Prdm16 PR/SET domain 16 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:30311386 NCBI chrNW_004936737:400,819...446,768 JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:23861362, PMID:24033266, PMID:25650408, PMID:25741868, PMID:26656175, PMID:27054166, PMID:27930701, PMID:28492532, PMID:31913406 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar PMID:15851227, PMID:16712702, PMID:18378609, PMID:18508782, PMID:19564561, PMID:19841300, PMID:20129283, PMID:22581653, PMID:22984773, PMID:23631430, PMID:23671135, PMID:23861362, PMID:24033266, PMID:24055113, PMID:25741868, PMID:25904541, PMID:28492532, PMID:30254039 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
G Sp4 Sp4 transcription factor ISO RGD PMID:11007485 RGD:1580019 NCBI chrNW_004936546:7,279,531...7,342,999 JBrowse link
G Tmem43 transmembrane protein 43 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac arrest
CTD
ClinVar
PMID:20435227, PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chrNW_004936602:104,424...113,692 JBrowse link
G Tnni3 troponin I3, cardiac type ISO ClinVar Annotator: match by term: Sudden cardiac arrest ClinVar PMID:21839045, PMID:25741868 NCBI chrNW_004936886:437,754...440,925 JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:17556660, PMID:23233322, PMID:24033266, PMID:24503780, PMID:25741868, PMID:28492532 NCBI chrNW_004936567:3,052,167...3,069,077 JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24019741, PMID:28492532 NCBI chrNW_004936664:3,093,258...3,124,473 JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
ClinVar PMID:19608031, PMID:24033266, PMID:25741868, PMID:26467025, PMID:28492532, PMID:30311386 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link
Sudden Cardiac Failure, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 inorganic pyrophosphatase 2 ISO OMIM NCBI chrNW_004936752:279,541...352,201 JBrowse link
systolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 ISO ClinVar Annotator: match by term: Heart failure, systolic ClinVar PMID:19525294, PMID:23299917, PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chrNW_004936601:3,502,844...3,510,919 JBrowse link
G Bmp10 bone morphogenetic protein 10 ISO CTD Direct Evidence: therapeutic CTD PMID:31712309 NCBI chrNW_004936491:13,180,086...13,186,004 JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Systolic heart failure ClinVar PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chrNW_004936534:5,029,008...5,076,467 JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A disease_progression ISO protein:increased expression:serum: RGD PMID:23564583 RGD:7257646 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Nppb natriuretic peptide B ISO associated with Renal Insufficiency;protein:increased expression:plasma: RGD PMID:23122795, PMID:23725445 RGD:7246908, RGD:7247627 NCBI chrNW_004936474:683,325...684,662 JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Heart failure, systolic ClinVar PMID:23861362, PMID:24033266, PMID:25163546, PMID:25741868, PMID:26467025, PMID:28492532 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11938
    disease of anatomical entity 11499
      cardiovascular system disease 3184
        heart disease 2260
          congestive heart failure 349
            Cardiac Edema 3
            Cardio-Renal Syndrome 1
            Cor pulmonale + 20
            Paroxysmal Dyspnea 2
            cardiac arrest + 56
            diastolic heart failure 31
            rheumatic congestive heart failure 0
            systolic heart failure 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.