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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:congestive heart failure
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Accession:DOID:6000 term browser browse the term
Definition:A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body. (DO)
Synonyms:exact_synonym: CHF;   Cardiac Failure;   Heart Decompensation;   Heart Failure;   Myocardial Failure;   congestive cardiac failure;   congestive heart disease;   weak heart
 narrow_synonym: Chronic Heart Failure;   advanced heart failure;   high output heart failure;   left sided heart failure;   moderate heart failure;   right sided heart failure;   symptomatic heart failure
 related_synonym: Beta-2-adrenoreceptor agonist, reduced response to;   Congestive heart failure and beta-blocker response, modifier of;   Congestive heart failure, modifier of
 primary_id: MESH:D006333
 xref: EFO:0000373;   EFO:0003144;   EFO:0003145;   EFO:0003146;   EFO:0003148;   EFO:0003149;   ICD10CM:I50;   ICD10CM:I50.9;   ICD9CM:428;   ICD9CM:428.0;   NCI:C3080;   NCI:C50577
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
congestive heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:16613899 PMID:16885549 PMID:18025408 PMID:18981553 PMID:21989597 More... NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161 		JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477 		JBrowse link
G Acads acyl-Coenzyme A dehydrogenase, short chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30827304 NCBI chr 5:115,248,358...115,257,405
Ensembl chr 5:115,248,358...115,257,405 		JBrowse link
G Acan aggrecan ISO mRNA:increased expression:myocardium RGD PMID:24595230 RGD:11570548 NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847 		JBrowse link
G Ace angiotensin I converting enzyme treatment ISO associated with Myocardial Infarction
CTD Direct Evidence: marker/mechanism
associated with Hypertension		 CTD
RGD		 PMID:18586661 PMID:19620082 PMID:15894569 PMID:22123369 RGD:2325224, RGD:12859272, RGD:6893472 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 IAGP
ISO		 mRNA, protein:increased expression:heart (human)
CTD Direct Evidence: marker/mechanism		 MouseDO
CTD
RGD		 PMID:25973029 PMID:32227090 RGD:40818416 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Acly ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826 		JBrowse link
G Actn2 actinin alpha 2 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr13:12,284,312...12,355,613
Ensembl chr13:12,284,312...12,355,641 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 treatment ISO associated with pulmonary hypertension RGD PMID:22628376 RGD:13703064 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with cardiovascular disease; protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:19367012 PMID:26670611 PMID:22032915 PMID:18192035 RGD:5686388, RGD:5686806 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin ISO RGD PMID:12623952 RGD:704370 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Adra2c adrenergic receptor, alpha 2c ISO DNA:deletion: :322_325del(human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of		 CTD
ClinVar
RGD		 PMID:12374873 PMID:17496726 PMID:12374873 RGD:1300355 NCBI chr 5:35,435,910...35,439,107
Ensembl chr 5:35,435,663...35,439,107 		JBrowse link
G Adrb1 adrenergic receptor, beta 1 ISO ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.R389G (human)		 ClinVar
CTD
RGD		 PMID:7586371 PMID:10212248 PMID:12374873 PMID:14502278 PMID:15816327 More... RGD:5129119, RGD:737774 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
protein:altered localization:cardiac muscle cell		 ClinVar
RGD		 PMID:8383511 PMID:15284533 PMID:16596417 PMID:19587314 PMID:20185685 RGD:5129119, RGD:4144900 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Adrb3 adrenergic receptor, beta 3 ISO protein:increased expression:left ventricle, myocardium (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart ventricle (rat)		 CTD
RGD		 PMID:15009959 PMID:17440824 PMID:11273992 PMID:21549119 RGD:5684398, RGD:5684917 NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644 		JBrowse link
G Ager advanced glycosylation end product-specific receptor severity ISO protein:increased expression:plasma (human) RGD PMID:20685687 RGD:7244134 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Agt angiotensinogen onset
severity
treatment		 ISO DNA:polymorphisms: :p.M235T, p.T174M (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 CTD
RGD		 PMID:1330361 PMID:12025466 PMID:20811386 PMID:17145981 PMID:24465706 More... RGD:1601140, RGD:11039412, RGD:8549482 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17208988 PMID:18214293 PMID:18586661 PMID:21963897 RGD:8549482 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA, protein:decreased expression:heart RGD PMID:18768398 PMID:21963897 RGD:6903846, RGD:8549482 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO DNA:SNP:CDS:V140I (rs37369) (human) RGD PMID:27423328 RGD:329961308 NCBI chr15:10,358,602...10,410,244
Ensembl chr15:10,358,618...10,410,239 		JBrowse link
G Akap6 A kinase anchor protein 6 IMP RGD PMID:24812305 RGD:11251930 NCBI chr12:52,745,371...53,202,351
Ensembl chr12:52,746,166...53,202,382 		JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr 5:3,977,410...4,130,204
Ensembl chr 5:3,978,054...4,131,310 		JBrowse link
G Alb albumin disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11771600 PMID:22158777 RGD:11036096 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO RGD PMID:15623566 RGD:5509787 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase treatment ISO
IDA		 associated with Myocardial Infarction; mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 PMID:34958945 PMID:19546247 RGD:1642301, RGD:401900155, RGD:5509627 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
G Ampd1 AMP deaminase 1 susceptibility ISO DNA:SNP:exon 2:CDNA:polymorphism:: RGD PMID:15135700 PMID:10086964 RGD:329349356, RGD:329349359 NCBI chr 3:102,981,330...103,007,038
Ensembl chr 3:102,981,330...103,007,036 		JBrowse link
G Ank2 ankyrin 2, brain ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999 		JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO associated with Cardiomyopathy, Congestive RGD PMID:15238456 RGD:2314858 NCBI chr 1:36,569,269...36,578,380
Ensembl chr 1:36,569,269...36,575,964
Ensembl chr 1:36,569,269...36,575,964 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 severity ISO protein:increased expression:plasma RGD PMID:11052858 RGD:2313827 NCBI chr11:101,221,432...101,230,256
Ensembl chr11:101,221,431...101,232,764 		JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:16129801 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608 		JBrowse link
G Apln apelin ISO protein:increased expression:ventricle myocardium
protein:decreased expression:plasma
associated with Hypertension, Pulmonary		 RGD PMID:17119870 PMID:16263185 PMID:17055480 RGD:1626186, RGD:1626175, RGD:1626171 NCBI chr  X:47,114,023...47,123,730
Ensembl chr  X:47,114,023...47,123,730 		JBrowse link
G Apoa1 apolipoprotein A-I ISO protein: decreased expression: serum RGD PMID:17517342 RGD:5508219 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoc1 apolipoprotein C-I ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoe apolipoprotein E ISO associated with Beta-Thalassemia RGD PMID:9787187 RGD:11039487 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Arg2 arginase type II ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075 		JBrowse link
G Arrb1 arrestin, beta 1 treatment ISO RGD PMID:21232674 RGD:5509888 NCBI chr 7:99,184,356...99,255,979
Ensembl chr 7:99,184,673...99,255,978 		JBrowse link
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18418421 NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383 		JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19776660 NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19776660 PMID:21691940 RGD:6903963 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18179782 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12145768 NCBI chr  X:72,935,371...72,938,034
Ensembl chr  X:72,935,708...72,939,108 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404 		JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:18097624 PMID:29746994 RGD:10054097, RGD:13792577 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:18097624 PMID:29746994 RGD:10054097, RGD:13792577 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Becn1 beclin 1, autophagy related treatment ISO RGD PMID:18619688 RGD:11560532 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO associated with Hypertension;protein:decreased expression:cardiac muscle cell RGD PMID:16257070 RGD:2293134 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 treatment ISO RGD PMID:23508759 RGD:11561982 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851 		JBrowse link
G Calr calreticulin IAGP MouseDO NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Casp1 caspase 1 IEP mRNA, protein:increased expression:heart left ventricle RGD PMID:17303764 RGD:2315913 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp12 caspase 12 treatment ISO associated with Hypertension
associated with myocardial infarction		 RGD PMID:18787714 PMID:27346262 RGD:2311453, RGD:13782169 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:29746994 RGD:13792577 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casq2 calsequestrin 2 ISO mRNA:increased expression:sinoatrial node RGD PMID:21565973 RGD:6771208 NCBI chr 3:101,993,731...102,053,830
Ensembl chr 3:101,993,731...102,053,830 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16105639 PMID:10618301 RGD:1581151 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cbl Casitas B-lineage lymphoma disease_progression ISO protein:increased expression:left ventricle myocardium, muscle cell (human)
DNA:mutations: :		 RGD PMID:24583314 PMID:33779075 RGD:11251947, RGD:155630627 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29959987 PMID:12950323 RGD:1581156 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccn1 cellular communication network factor 1 severity ISO protein:increased expression:blood serum (human) RGD PMID:30045012 RGD:329845515 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17229371 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Ccna2 cyclin A2 IMP RGD PMID:16820573 RGD:2293348 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnt1 cyclin T1 IMP RGD PMID:15297879 RGD:1556509 NCBI chr15:98,436,570...98,468,340
Ensembl chr15:98,436,570...98,468,804 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12719858 RGD:1581177 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:15716285 RGD:2314219 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cdk9 cyclin dependent kinase 9 ISO
IEP		 protein:increased activity:ventricle:
protein:increased activity:heart:		 RGD PMID:15297879 PMID:15297879 RGD:1556509, RGD:1556509 NCBI chr 2:32,595,794...32,608,098
Ensembl chr 2:32,595,796...32,603,088 		JBrowse link
G Cfd complement factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO mRNA,protein:increased expression:cardiomyocyte: RGD PMID:11033112 RGD:11341730 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Chdh choline dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:29,730,957...29,762,423
Ensembl chr14:29,730,980...29,762,484 		JBrowse link
G Chek2 checkpoint kinase 2 ISO protein:increased phosphorylation:heart myocardium RGD PMID:12702777 RGD:2289708 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:plasma (human) RGD PMID:19961288 RGD:4892629 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033 		JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339 		JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855 		JBrowse link
G Corin corin, serine peptidase ISO mRNA:increased expression:heart (rat)
mRNA:decreased expression:left atrium, right atrium (rat)		 RGD PMID:15191894 PMID:15155264 RGD:1581217, RGD:1581218 NCBI chr 5:72,457,291...72,661,884
Ensembl chr 5:72,457,368...72,661,816 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO RGD PMID:34373768 RGD:401960872 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cryab crystallin, alpha B ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:1560021 PMID:2299599 PMID:16483541 PMID:16793013 PMID:17116488 More... NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936 		JBrowse link
G Crym crystallin, mu ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 7:119,785,603...119,801,212
Ensembl chr 7:119,785,603...119,801,334 		JBrowse link
G Cs citrate synthase severity
treatment		 ISO CTD Direct Evidence: marker/mechanism
associated with pulmonary hypertension		 CTD
RGD		 PMID:8922916 PMID:7484170 PMID:23099843 PMID:28492791 RGD:243049253, RGD:243048480, RGD:243048466 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) ISO CTD Direct Evidence: marker/mechanism CTD PMID:11732872 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585077 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 IAGP MouseDO NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781 		JBrowse link
G Cst3 cystatin C susceptibility ISO protein:increased expression:serum (human) RGD PMID:19539088 RGD:2314311 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO mRNA, protein:increased expression: paraventricular nucleus of hypothalamus RGD PMID:24036597 RGD:9491792 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IAGP MouseDO NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 ISO protein:increased expression:heart (rat) RGD PMID:19571523 RGD:4891162 NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,859...74,728,167 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 treatment ISO RGD PMID:34958945 RGD:401900155 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772 		JBrowse link
G Ddr1 discoidin domain receptor family, member 1 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513 		JBrowse link
G Dio3 deiodinase, iodothyronine type III ISO associated with Hypertrophy, Right Ventricular;mRNA, protein:increased expression:heart right ventricle RGD PMID:18259611 RGD:2303417 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531 		JBrowse link
G Dmd dystrophin, muscular dystrophy ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr  X:81,858,244...84,248,656
Ensembl chr  X:81,992,476...84,249,747 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:atrium: RGD PMID:23573917 RGD:9588286 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dstn destrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 2:143,757,251...143,785,244
Ensembl chr 2:143,757,240...143,785,244 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO protein:increased expression:paraventricular nucleus RGD PMID:23832698 RGD:7257598 NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058 		JBrowse link
G Dyrk1a dual-specificity tyrosine phosphorylation regulated kinase 1a treatment ISO associated with myocardial infarction RGD PMID:26067684 RGD:11097969 NCBI chr16:94,370,770...94,496,378
Ensembl chr16:94,370,869...94,496,376 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney:
associated with myocardial ischemia		 RGD PMID:11145756 PMID:9595392 PMID:19596829 RGD:1580911, RGD:7244244, RGD:7243876 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540 		JBrowse link
G Edn1 endothelin 1 severity
treatment		 ISO protein:increased secretion:plasma (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart:		 CTD
RGD		 PMID:7967349 PMID:7969316 PMID:9861300 PMID:11136700 PMID:11707688 More... RGD:4144845, RGD:8661798, RGD:7244167 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ednra endothelin receptor type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093 		JBrowse link
G Ednrb endothelin receptor type B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144 		JBrowse link
G Endog endonuclease G ISO mRNa:decreased expression:heart: RGD PMID:17292393 RGD:9685393 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081 		JBrowse link
G Eng endoglin treatment ISO protein:increased expression:heart left ventricle (rat) RGD PMID:20156938 PMID:20156938 RGD:7257540, RGD:7257540 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic ISO CTD Direct Evidence: marker/mechanism CTD PMID:18443590 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Epo erythropoietin treatment ISO associated with Myocardial Infarction RGD PMID:20139114 RGD:10401073 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:10421602 RGD:1580989 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO associated with Aortic Valve Stenosis;mRNA, protein:decreased expression:heart myocardium RGD PMID:10421602 RGD:1580989 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218 		JBrowse link
G Esrra estrogen related receptor, alpha ISO protein:decreased expression:heart: RGD PMID:21825219 RGD:10401867 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 ISO DNA:deletion:introns, exon (human)
ClinVar Annotator: match by term: Congestive heart failure		 ClinVar
RGD		 PMID:25741868 PMID:28492532 PMID:15735644 RGD:1598455 NCBI chr10:22,978,861...23,226,785
Ensembl chr10:22,978,862...23,226,684 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO DNA:mutations: : RGD PMID:33779075 RGD:155630627 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G Fads1 fatty acid desaturase 1 treatment ISO RGD PMID:22796714 RGD:401901592 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241 		JBrowse link
G Fads2 fatty acid desaturase 2 treatment ISO associated with Left Ventricular Hypertrophy, Cardiac Fibrosis RGD PMID:24284026 PMID:22796714 RGD:401901245, RGD:401901592 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110 		JBrowse link
G Fas Fas cell surface death receptor treatment ISO mRNA:splice variant:heart left ventricle (human) RGD PMID:9367848 PMID:29746994 RGD:8686420, RGD:13792577 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand treatment ISO RGD PMID:29746994 RGD:13792577 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fbln5 fibulin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189163 NCBI chr12:101,712,820...101,785,541
Ensembl chr12:101,712,824...101,785,314 		JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chr 5:74,695,774...74,759,451
Ensembl chr 5:74,696,110...74,759,461 		JBrowse link
G Fkbp1b FK506 binding protein 1b ISO associated with Shock, Septic RGD PMID:17637193 RGD:2302075 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591 		JBrowse link
G Fos FBJ osteosarcoma oncogene ISO RGD PMID:15623567 RGD:2293777 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Fosl1 fos-like antigen 1 ISO RGD PMID:15623567 RGD:2293777 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974 		JBrowse link
G Foxc1 forkhead box C1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459 		JBrowse link
G Foxc2 forkhead box C2 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 8:121,842,910...121,845,634
Ensembl chr 8:121,842,910...121,845,634 		JBrowse link
G Foxo1 forkhead box O1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642 		JBrowse link
G Foxp1 forkhead box P1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
G Foxp4 forkhead box P4 ISO RGD PMID:16952980 RGD:1582564 NCBI chr17:48,178,058...48,235,401
Ensembl chr17:48,178,058...48,235,570 		JBrowse link
G Fth1 ferritin heavy polypeptide 1 ISO protein:decreased expression:heart RGD PMID:18992754 RGD:2315110 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase treatment ISO
IEP
IMP		 mRNA, protein:decreased expression:heart
mRNA:increased expression:heart
protein:increased expression:heart		 RGD PMID:29997116 PMID:33748197 PMID:36120562 PMID:34728610 RGD:329812009, RGD:329901854, RGD:329901853, RGD:329812038 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 ISO protein:increased serine phosphorylation:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chr 7:30,751,103...30,758,332
Ensembl chr 7:30,751,103...30,756,624 		JBrowse link
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:left ventricle myocardium		 CTD
RGD		 PMID:16820567 PMID:36071497 PMID:16820567 RGD:329955376 NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784 		JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:7608802 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment ISO RGD PMID:30878404 RGD:329961332 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Ghrl ghrelin ISO CTD Direct Evidence: therapeutic CTD PMID:20572026 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide disease_progression
no_association		 ISO
IAGP		 DNA:polymorphism:promoter:[-694C>T;-695G>T] (human)
DNA:polymorphisms:promoter:multiple		 MouseDO
RGD		 PMID:17720980 PMID:17720980 RGD:126781754, RGD:126781754 NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827 		JBrowse link
G Gnb1 guanine nucleotide binding protein (G protein), beta 1 disease_progression ISO DNA:mutations: : RGD PMID:33779075 RGD:155630627 NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726 		JBrowse link
G Gp6 glycoprotein 6 (platelet) ISO protein:increased expression, decreased expression:plasma, platelet (human) RGD PMID:27601054 RGD:401794406 NCBI chr 7:4,365,852...4,400,849
Ensembl chr 7:4,366,964...4,400,743 		JBrowse link
G Gpx4 glutathione peroxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Grk1 G protein-coupled receptor kinase 1 ISO RGD PMID:12456492 RGD:1600002 NCBI chr 8:13,455,081...13,471,951
Ensembl chr 8:13,455,081...13,471,951 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IAGP
ISO		 mRNA:decreased expression:peripheral blood mononuclear cell (human)
CTD Direct Evidence: marker/mechanism
associated with Hypertrophy, Left Ventricular and Hypertension;protein:increased expression, increased activity:heart left ventricle, cytosol (rat)		 CTD
RGD		 PMID:26670611 PMID:11331748 PMID:26248277 PMID:29247373 PMID:9931137 RGD:737776, RGD:11535540, RGD:13506830, RGD:1625790 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 severity ISO mRNA:decreased expression:heart left ventricle (human) RGD PMID:22685168 RGD:13506835 NCBI chr 5:113,058,344...113,163,518
Ensembl chr 5:113,058,348...113,163,657 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 severity ISO mRNA:decreased expression:heart left ventricle (human)
mRNA:decreased expression:peripheral blood mononuclear cell (human)		 RGD PMID:22685168 PMID:26248277 RGD:13506835, RGD:11535540 NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406 		JBrowse link
G Grp gastrin releasing peptide exacerbates ISO protein:increased expression:plasma (human)
protein:decreased expression:plasma (human)		 RGD PMID:30145817 PMID:1396815 RGD:329961562, RGD:401700398 NCBI chr18:66,005,826...66,019,670
Ensembl chr18:66,005,891...66,019,667 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901358 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G H19 H19, imprinted maternally expressed transcript severity ISO CTD Direct Evidence: marker/mechanism
associated with ischemic cardiomyopathy; RNA:increased expression:heart left ventricle (human)		 CTD
RGD		 PMID:36071497 PMID:27317124 RGD:243048444 NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,131,917 		JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:serum, urine RGD PMID:21080339 RGD:11041621 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 8:57,774,018...57,777,552
Ensembl chr 8:57,774,018...57,777,668 		JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:58,730,232...58,770,458
Ensembl chr 9:58,730,695...58,770,458 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO protein:increased expression:heart right ventricle (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15732037 PMID:17582388 RGD:9068910 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO protein:decreased expression:heart RGD PMID:23708738 PMID:24204700 RGD:10402070, RGD:10402081 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22352330 PMID:23592614 RGD:10755584 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hotair HOX transcript antisense RNA (non-protein coding) severity ISO associated with ischemic cardiomyopathy; RNA:decreased expression:heart left ventricle (human) RGD PMID:27317124 RGD:243048444 NCBI chr15:102,852,497...102,856,381
Ensembl chr15:102,852,494...102,856,165 		JBrowse link
G Hottip Hoxa distal transcript antisense RNA ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:52,239,760...52,244,588
Ensembl chr 6:52,239,760...52,244,588 		JBrowse link
G Hoxa11os homeobox A11, opposite strand ISO CTD Direct Evidence: marker/mechanism
associated with ischemic cardiomyopathy; RNA:increased expression:heart left ventricle (human)		 CTD
RGD		 PMID:36071497 PMID:27317124 RGD:243048444 NCBI chr 6:52,222,013...52,226,770
Ensembl chr 6:52,221,373...52,226,779 		JBrowse link
G Hp haptoglobin treatment ISO RGD PMID:23494325 RGD:11041812 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Hrh2 histamine receptor H2 susceptibility IMP RGD PMID:24655024 RGD:9685523 NCBI chr13:54,345,990...54,390,201
Ensembl chr13:54,346,148...54,390,199 		JBrowse link
G Hsf1 heat shock factor 1 ISO protein:altered localization:heart left ventricle (rat) RGD PMID:24285117 RGD:10402754 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hspb1 heat shock protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17481944 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO mRNA:increased expression:heart left ventricle RGD PMID:16002744 RGD:1600503 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934 		JBrowse link
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B ISO mRNA:increased expression:left ventricle cardiac muscle (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19023134 PMID:17936780 RGD:9698457 NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:3091246 PMID:20938210 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:12835956 RGD:1598415 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il10 interleukin 10 disease_progression
treatment		 ISO mRNA, protein:decreased expression:cardiac ventricle (rat) RGD PMID:16461369 PMID:28939262 PMID:23778495 RGD:1598465, RGD:14975271, RGD:7365020 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il17a interleukin 17A ISO protein:increased expression:heart RGD PMID:19909738 PMID:19527710 RGD:2325816, RGD:4831836 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15135663 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 ISO associated with Hypertension;mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental; protein:increased expression:extracellular space (rat)		 CTD
RGD		 PMID:15135663 PMID:16360360 PMID:18280594 PMID:28939262 PMID:18999900 RGD:5128682, RGD:14975271, RGD:2307285 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6ra interleukin 6 receptor, alpha ISO protein:increased expression:paraventricular hypothalamic nucleus RGD PMID:17095650 RGD:1625433 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Inhba inhibin beta-A severity ISO mRNA, protein:increased expression:PBMC, Tcells, serum (human)
protein:increased expression:heart (rat)		 RGD PMID:14993131 PMID:22884154 RGD:1580888, RGD:329849007 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206 		JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:15628829 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Irx1 Iroquois homeobox 1 treatment ISO RGD PMID:31640472 RGD:329950496 NCBI chr13:72,106,351...72,111,842
Ensembl chr13:72,106,040...72,111,842 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884376 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Kat8 K(lysine) acetyltransferase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27768893 NCBI chr 7:127,511,689...127,525,010
Ensembl chr 7:127,511,688...127,525,009 		JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 ISO associated with Myocardial Infarction (RDO:0006167); mRNA:increased expression:heart left ventricle, septum (rat)
mRNA:increased expression:endocardium of right ventricle:		 RGD PMID:16497176 PMID:17384445 RGD:1642301, RGD:12910696 NCBI chr16:92,142,889...92,156,356
Ensembl chr16:92,142,870...92,156,356 		JBrowse link
G Kcnk2 potassium channel, subfamily K, member 2 ISO associated with Hypertension, Pulmonary:mRNA:decreased expression:heart right ventricle (rat) RGD PMID:25016242 RGD:9831185 NCBI chr 1:188,940,127...189,134,951
Ensembl chr 1:188,940,127...189,134,470 		JBrowse link
G Kdm2a lysine (K)-specific demethylase 2A IEP protein:altered localization:promoter (mouse) RGD PMID:25181347 RGD:9588275 NCBI chr19:4,366,172...4,448,749
Ensembl chr19:4,364,447...4,448,313 		JBrowse link
G Lep leptin IMP RGD PMID:18006469 RGD:5128823 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lepr leptin receptor IEP
ISO		 protein:increased phosphorylation:heart
DNA:mutations:cds: : (rat)		 RGD PMID:18006469 PMID:32710530 RGD:5128823, RGD:401960103 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO RGD PMID:15520318 RGD:9685214 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Lif leukemia inhibitory factor ISO RGD PMID:20051627 RGD:2326058 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514 		JBrowse link
G Lrrc10 leucine rich repeat containing 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr10:116,881,246...116,882,673
Ensembl chr10:116,881,246...116,882,673 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO associated with dyspnea;protein:increased expression:plasma (human)
mRNA:increased expression:heart (human)		 RGD PMID:22587491 PMID:32478206 RGD:156451376, RGD:213230162 NCBI chr12:84,829,986...84,923,581
Ensembl chr12:84,829,986...84,923,306 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP protein:increased activity:heart: RGD PMID:17562954 RGD:10412331 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 treatment IMP
IEP		 RGD PMID:25278099 PMID:10802712 PMID:26706286 RGD:11534146, RGD:155804285, RGD:155791673 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mapk10 mitogen-activated protein kinase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200 		JBrowse link
G Mas1 MAS1 oncogene ISO mRNA, protein:decreased expression:heart RGD PMID:21963897 RGD:8549482 NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030 		JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) ISO RGD PMID:16786185 RGD:1582470 NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252 		JBrowse link
G Med1 mediator complex subunit 1 IAGP MouseDO NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119 		JBrowse link
G Mir106b microRNA 106b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 5:138,163,999...138,164,080
Ensembl chr 5:138,163,999...138,164,080 		JBrowse link
G Mir107 microRNA 107 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr19:34,798,087...34,798,173
Ensembl chr19:34,798,087...34,798,173 		JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141 		JBrowse link
G Mir126a microRNA 126a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 2:26,481,369...26,481,441
Ensembl chr 2:26,481,369...26,481,441 		JBrowse link
G Mir133a-2 microRNA 133a-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 2:180,040,172...180,040,275
Ensembl chr 2:180,040,172...180,040,275 		JBrowse link
G Mir140 microRNA 140 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945 		JBrowse link
G Mir143 microRNA 143 severity ISO RGD PMID:29728596 RGD:155882581 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329 		JBrowse link
G Mir144 microRNA 144 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896 		JBrowse link
G Mir145a microRNA 145a disease_progression
treatment		 ISO associated with acute myocardial infarction; miRNA:decreased expression:blood plasma (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:36071497 PMID:28051023 PMID:32554856 RGD:155260283, RGD:155260293 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965 		JBrowse link
G Mir148a microRNA 148a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890 		JBrowse link
G Mir150 microRNA 150 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 7:44,771,181...44,771,245
Ensembl chr 7:44,771,181...44,771,245 		JBrowse link
G Mir151 microRNA 151 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr15:73,126,664...73,126,731
Ensembl chr15:73,126,664...73,126,731 		JBrowse link
G Mir15a microRNA 15a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:61,869,476...61,869,559
Ensembl chr14:61,869,476...61,869,559 		JBrowse link
G Mir15b microRNA 15b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168 		JBrowse link
G Mir17 microRNA 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186 		JBrowse link
G Mir18 microRNA 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:115,281,283...115,281,378
Ensembl chr14:115,281,283...115,281,378 		JBrowse link
G Mir18b microRNA 18b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr  X:51,831,208...51,831,290
Ensembl chr  X:51,831,208...51,831,290 		JBrowse link
G Mir191 microRNA 191 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 9:108,445,518...108,445,591
Ensembl chr 9:108,445,518...108,445,591 		JBrowse link
G Mir193b microRNA 193b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr16:13,267,387...13,267,465
Ensembl chr16:13,267,387...13,267,465 		JBrowse link
G Mir195a microRNA 195a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr11:70,125,868...70,125,961
Ensembl chr11:70,125,868...70,125,961 		JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:115,281,432...115,281,513
Ensembl chr14:115,281,432...115,281,513 		JBrowse link
G Mir20a microRNA 20a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:115,281,589...115,281,695
Ensembl chr14:115,281,589...115,281,695 		JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069 		JBrowse link
G Mir210 microRNA 210 severity ISO associated with Dyspnea; miRNA:increased expression:blood serum (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:36071497 PMID:33783502 RGD:155269041 NCBI chr 7:140,801,297...140,801,406
Ensembl chr 7:140,801,297...140,801,406 		JBrowse link
G Mir21a microRNA 21a disease_progression
treatment		 IEP
ISO
IMP		 CTD Direct Evidence: marker/mechanism
RNA:increased expression:left ventricular myocardium
RNA:increased expression:heart, myofibroblast:		 CTD
RGD		 PMID:36071497 PMID:19043405 PMID:19043405 PMID:19043405 PMID:19043405 RGD:41404712, RGD:41404712, RGD:41404712, RGD:41404712 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir23a microRNA 23a ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Mir26b microRNA 26b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 1:74,433,469...74,433,553
Ensembl chr 1:74,433,469...74,433,553 		JBrowse link
G Mir27a microRNA 27a ISO RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387 		JBrowse link
G Mir28a microRNA 28a ISO RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr16:24,646,605...24,646,690
Ensembl chr16:24,646,605...24,646,690 		JBrowse link
G Mir29c microRNA 29c ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 1:194,719,855...194,719,942
Ensembl chr 1:194,719,855...194,719,942 		JBrowse link
G Mir301 microRNA 301 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr11:87,003,830...87,003,915
Ensembl chr11:87,003,830...87,003,915 		JBrowse link
G Mir30b microRNA 30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr15:68,209,264...68,209,359
Ensembl chr15:68,209,264...68,209,359 		JBrowse link
G Mir30e microRNA 30e ISO miRNA:decreased expression:heart (rat) RGD PMID:25950484 RGD:11541106 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894 		JBrowse link
G Mir326 microRNA 326 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 7:99,201,476...99,201,570
Ensembl chr 7:99,201,476...99,201,570 		JBrowse link
G Mir342 microRNA 342 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr12:108,624,879...108,624,977
Ensembl chr12:108,624,879...108,624,977 		JBrowse link
G Mir34a microRNA 34a ISO RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012 		JBrowse link
G Mir361 microRNA 361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr  X:111,984,521...111,984,590
Ensembl chr  X:111,984,521...111,984,590 		JBrowse link
G Mir409 microRNA 409 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr12:109,709,592...109,709,670
Ensembl chr12:109,709,592...109,709,670 		JBrowse link
G Mir423 microRNA 423 ISO miRNA:increased expression:plasma RGD PMID:20185794 RGD:158014892 NCBI chr11:76,968,890...76,968,998
Ensembl chr11:76,968,890...76,968,998 		JBrowse link
G Mir484 microRNA 484 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr16:13,977,490...13,977,556
Ensembl chr16:13,977,490...13,977,556 		JBrowse link
G Mir494 microRNA 494 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr  X:7,114,641...7,114,736
Ensembl chr  X:7,114,641...7,114,736 		JBrowse link
G Mir574 microRNA 574 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 5:65,127,661...65,127,738
Ensembl chr 5:65,127,661...65,127,738 		JBrowse link
G Mir664 microRNA 664 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 1:184,975,172...184,975,240
Ensembl chr 1:184,975,172...184,975,240 		JBrowse link
G Mir93 microRNA 93 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 5:138,163,785...138,163,872
Ensembl chr 5:138,163,785...138,163,872 		JBrowse link
G Mir96 microRNA 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550 		JBrowse link
G Mir98 microRNA 98 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317 		JBrowse link
G Mir99b microRNA 99b ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr17:18,050,450...18,050,519
Ensembl chr17:18,050,450...18,050,519 		JBrowse link
G Mirlet7g microRNA let7g ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 9:106,056,039...106,056,126
Ensembl chr 9:106,056,039...106,056,126 		JBrowse link
G Mirlet7i microRNA let7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr10:122,821,545...122,821,629
Ensembl chr10:122,821,545...122,821,629 		JBrowse link
G Mme membrane metallo endopeptidase ISO RGD PMID:12383878 RGD:13801043 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451 		JBrowse link
G Mmp13 matrix metallopeptidase 13 disease_progression ISO protein:increased expression:left ventricle (rat)
associated with Hypertension		 RGD PMID:10773235 PMID:10773234 RGD:1582587, RGD:2290467 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) disease_progression ISO protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) ISO RGD PMID:12892382 PMID:21866669 RGD:1582539, RGD:7207282 NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO RGD PMID:12892382 PMID:21866669 RGD:1582539 RGD:7207282 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO mRNA:increased expression:heart left ventricle
protein:increased expression:heart left ventricle, plasma		 RGD PMID:10773234 PMID:20606426 PMID:16169329 RGD:2290467, RGD:8694112, RGD:1582574 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein:increased expression:heart left ventricle, plasma RGD PMID:20606426 RGD:8694112 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp8 matrix metallopeptidase 8 disease_progression ISO protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chr 9:7,558,430...7,568,487
Ensembl chr 9:7,558,457...7,568,486 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO associated with Hypertension, Pulmonary; protein:increased expression:heart
protein:increased expression:heart left ventricle, plasma		 RGD PMID:17913382 PMID:20606426 PMID:11342481 PMID:16952784 RGD:5130174, RGD:8694112, RGD:7207137, RGD:1582647 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mstn myostatin ISO mRNA, protein:increased expression:myocardium
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16968467 PMID:16968467 RGD:2303554 NCBI chr 1:53,100,799...53,107,238
Ensembl chr 1:53,100,799...53,107,238 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO mRNA, protein:increased expression:heart RGD PMID:20861467 RGD:10003169 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Mtpn myotrophin IAGP MouseDO NCBI chr 6:35,485,759...35,516,823
Ensembl chr 6:35,485,841...35,516,823 		JBrowse link
G Mx1 MX dynamin-like GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha treatment ISO mRNA:decreased expression:heart left ventricle
ClinVar Annotator: match by term: Congestive heart failure | ClinVar Annotator: match by term: Heart failure
associated with Myocardial Infarction		 ClinVar
RGD		 PMID:20656787 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 More... RGD:1580923, RGD:12792974 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta treatment ISO associated with Myocardial Infarction RGD PMID:18088389 RGD:12792974 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:12404107 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535 		JBrowse link
G Myoc myocilin ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 1:162,466,719...162,477,263
Ensembl chr 1:162,466,724...162,477,262 		JBrowse link
G Myocd myocardin IMP RGD PMID:19850880 RGD:11251948 NCBI chr11:65,064,434...65,160,821
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Myod1 myogenic differentiation 1 treatment ISO associated with Aortic Valve Stenosis RGD PMID:20060348 RGD:9686081 NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523 		JBrowse link
G Myot myotilin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:19240791 PMID:25741868 PMID:26257771 PMID:26467025 PMID:28492532 More... NCBI chr18:44,467,126...44,488,795
Ensembl chr18:44,467,141...44,488,791 		JBrowse link
G Mypn myopalladin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:22286171 PMID:23299917 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr10:62,951,574...63,039,731
Ensembl chr10:62,951,574...63,039,731 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO mRNA, protein:increased expression:heart RGD PMID:19853610 RGD:2325979 NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:28373008 PMID:29373037 RGD:26923905 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) ISO associated with Myocardial Infarction;mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Nisch nischarin ISO RGD PMID:12021582 RGD:1581128 NCBI chr14:30,892,885...30,928,783
Ensembl chr14:30,892,887...30,938,903 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO protein:increased expression:heart, left ventricle, sarcolemma (human) RGD PMID:11121795 RGD:5132888 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO RGD PMID:15466641 PMID:23832698 RGD:1581144, RGD:7257598 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos1ap nitric oxide synthase 1 (neuronal) adaptor protein ISO mRNA:increased expression:brain RGD PMID:21831995 RGD:7327163 NCBI chr 1:170,143,039...170,417,371
Ensembl chr 1:170,130,237...170,417,430 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD PMID:19168511 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19168511 PMID:20304815 PMID:29351461 RGD:13504746 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nox1 NADPH oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr  X:132,987,170...133,038,455
Ensembl chr  X:132,987,170...133,122,705 		JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Nppa natriuretic peptide precursor type A treatment
severity		 ISO mRNA,protein:increased expression:heart,plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma		 CTD
RGD		 PMID:1647690 PMID:8112904 PMID:11136700 PMID:16101196 PMID:11421854 More... RGD:1580139, RGD:7297049, RGD:7247714, RGD:1580140 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nppb natriuretic peptide type B severity ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus;protein:increased expression:plasma
mRNA,protein:increased expression:heart,plasma		 CTD
RGD		 PMID:11136700 PMID:11279304 PMID:12628948 PMID:15732037 PMID:15860969 More... RGD:1580140, RGD:7247316, RGD:1642196, RGD:1580139 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP
ISO
IEP		 associated with Hypertension
CTD Direct Evidence: marker/mechanism
protein:decreased expression:kidney		 CTD
RGD		 PMID:20881240 PMID:9405681 PMID:17264312 RGD:737701, RGD:7247730 NCBI chr 3:90,357,898...90,373,235
Ensembl chr 3:90,357,898...90,373,173 		JBrowse link
G Nptxr neuronal pentraxin receptor ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr15:79,670,552...79,688,910
Ensembl chr15:79,670,552...79,688,967 		JBrowse link
G Npy neuropeptide Y ISO RGD PMID:17804485 RGD:7175103 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment ISO RGD PMID:21737535 RGD:7174712 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15722665 PMID:21321305 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641 		JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19801490 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715 		JBrowse link
G Ogdhl oxoglutarate dehydrogenase-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr14:32,043,941...32,070,108
Ensembl chr14:32,043,976...32,070,108 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) ISO protein:increased expression:heart left ventricle (rat) RGD PMID:22128088 RGD:9590202 NCBI chr  X:100,683,617...100,727,957
Ensembl chr  X:100,683,666...100,727,957 		JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase ISO protein:decreased expression:heart RGD PMID:19493956 RGD:7800717 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702 		JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO mRNA, protein:increased expression:left heart ventricle RGD PMID:26365878 RGD:401900132 NCBI chr 1:5,658,673...5,676,357
Ensembl chr 1:5,658,689...5,676,354 		JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801 		JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 2:102,380,325...102,473,386
Ensembl chr 2:102,380,357...102,473,386 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 treatment ISO associated with Hypertension RGD PMID:19443425 RGD:11074236 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IEP protein:decreased expression:heart: RGD PMID:23647599 RGD:10448278 NCBI chr10:7,503,608...7,556,922
Ensembl chr10:7,505,137...7,556,900 		JBrowse link
G Pde9a phosphodiesterase 9A severity
treatment		 ISO mRNA:increased expression:heart, peripheral blood mononuclear cell RGD PMID:33787083 PMID:28649129 RGD:240191787, RGD:241060360 NCBI chr17:31,605,079...31,695,284
Ensembl chr17:31,605,184...31,695,284 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19429709 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898 		JBrowse link
G Pdyn prodynorphin ISO mRNA, protein:increased expression:left heart ventricle RGD PMID:26365878 RGD:401900132 NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:19327525 RGD:6483590 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Phf6 PHD finger protein 6 disease_progression ISO DNA:mutations: : RGD PMID:33779075 RGD:155630627 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12963636 PMID:15936620 RGD:6482699 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ISO RGD PMID:16952920 RGD:6482778 NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092 		JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plcd1 phospholipase C, delta 1 ISO RGD PMID:11181012 RGD:2300431 NCBI chr 9:118,900,595...118,922,570
Ensembl chr 9:118,900,595...118,922,570 		JBrowse link
G Pld2 phospholipase D2 ISO protein:increased expression:heart left ventricle RGD PMID:15601581 RGD:2299908 NCBI chr11:70,430,318...70,448,936
Ensembl chr11:70,430,890...70,448,936 		JBrowse link
G Pln phospholamban treatment ISO associated with Hypertension
associated with Myocardial Infarction		 RGD PMID:22970977 PMID:22947202 RGD:7327181, RGD:7327182 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35218467 NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:3026683 PMID:8277081 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Postn periostin, osteoblast specific factor treatment ISO mRNA:increased expression:heart RGD PMID:16414453 PMID:15381649 RGD:10040951, RGD:10040999 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha onset IDA
IAGP
ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:heart (mouse)		 MouseDO
CTD
RGD		 PMID:19808358 PMID:22503866 PMID:23342071 PMID:23297372 RGD:7241838, RGD:7241843 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Ppm1k protein phosphatase 1K (PP2C domain containing) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:57,483,487...57,512,537
Ensembl chr 6:57,483,487...57,512,453 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha IMP RGD PMID:12024026 RGD:737728 NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO protein:increased expression:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chr 5:122,296,338...122,313,336
Ensembl chr 5:122,296,341...122,313,336 		JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A ISO CTD Direct Evidence: therapeutic CTD PMID:20071777 NCBI chr15:103,438,706...103,446,465
Ensembl chr15:103,438,706...103,446,430 		JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform ISO mRNA:increased expression:vastus lateralis muscle (human) RGD PMID:14567976 RGD:8693707 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605 		JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072 		JBrowse link
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit ISO ClinVar Annotator: match by term: Congestive heart failure | ClinVar Annotator: match by term: Heart failure ClinVar PMID:21409595 PMID:24033266 PMID:25741868 PMID:27532257 PMID:28492532 NCBI chr 5:25,067,733...25,311,576
Ensembl chr 5:25,067,742...25,305,640 		JBrowse link
G Prkar2a protein kinase, cAMP dependent regulatory, type II alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chr 9:108,569,342...108,627,643
Ensembl chr 9:108,566,513...108,627,635 		JBrowse link
G Prkar2b protein kinase, cAMP dependent regulatory, type II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr12:32,008,468...32,111,639
Ensembl chr12:32,008,475...32,111,295 		JBrowse link
G Prkca protein kinase C, alpha ISO protein:increased expression, increased phosphorylation:heart left ventricle RGD PMID:17556659 RGD:2292480 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754 		JBrowse link
G Prkcb protein kinase C, beta ISO associated with hypertension RGD PMID:12392998 RGD:1625516 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18926768 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188 		JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase treatment ISO RGD PMID:27802898 RGD:401960097 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17162251 PMID:21939825 RGD:7242422 NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777 		JBrowse link
G Ptprf protein tyrosine phosphatase receptor type F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16155095 PMID:12642504 RGD:1581295 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Ramp2 receptor (calcitonin) activity modifying protein 2 ISO associated with Hypertension RGD PMID:12623952 RGD:704370 NCBI chr11:101,137,160...101,139,076
Ensembl chr11:101,136,854...101,150,372 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 ISO mRNA, protein:increased expression:left ventricle myocardium (human) RGD PMID:18323524 RGD:9835356 NCBI chr15:97,637,886...97,666,300
Ensembl chr15:97,642,651...97,665,853 		JBrowse link
G Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 IEP protein:decreased expression:heart (mouse) RGD PMID:25753418 RGD:329845877 NCBI chr15:76,963,190...77,193,058
Ensembl chr15:76,963,190...77,191,204 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO protein:decreased expression:heart RGD PMID:30257214 RGD:151667449 NCBI chr  X:20,483,596...20,517,128
Ensembl chr  X:20,483,742...20,517,140 		JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868 PMID:28492532 PMID:31376648 NCBI chr19:53,649,422...53,855,514
Ensembl chr19:53,665,737...53,855,511 		JBrowse link
G Rbp4 retinol binding protein 4, plasma treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26670611 PMID:22785609 RGD:329845590 NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729 		JBrowse link
G Ren1 renin 1 structural exacerbates ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:blood plasma (human)		 CTD
RGD		 PMID:1647690 PMID:7034517 PMID:20811386 PMID:17526990 RGD:126908011 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
G Retn resistin ISO associated with Coronary Disease
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:26670611 PMID:22240747 RGD:7207075 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110 		JBrowse link
G Rmst rhabdomyosarcoma 2 associated transcript (non-coding RNA) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr10:91,917,608...92,001,040
Ensembl chr10:91,906,899...92,001,132 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO RGD PMID:21297953 RGD:7327162 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824 		JBrowse link
G Rpph1 ribonuclease P RNA component H1 severity ISO associated with ischemic cardiomyopathy; RNA:increased expression:heart left ventricle (human) RGD PMID:27317124 RGD:243048444 NCBI chr14:51,044,904...51,045,228
Ensembl chr14:51,044,906...51,045,224 		JBrowse link
G Rrad Ras-related associated with diabetes ISO mRNA, protein:decreased expression:heart RGD PMID:18056528 RGD:2311701 NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451 		JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle ISO
IDA		 RGD PMID:29593014 PMID:29593014 RGD:329813079, RGD:329813079 NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604 		JBrowse link
G Ryr2 ryanodine receptor 2, cardiac ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar
RGD		 PMID:25741868 PMID:28404607 PMID:28492532 PMID:16483256 RGD:1599251 NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831 		JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318 		JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO mRNA:decreased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chr 9:119,312,470...119,408,096
Ensembl chr 9:119,312,474...119,408,082 		JBrowse link
G Scn8a sodium channel, voltage-gated, type VIII, alpha ISO mRNA:increased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chr15:100,766,600...100,943,819
Ensembl chr15:100,767,739...100,943,819 		JBrowse link
G Selp selectin, platelet ISO RGD PMID:19193626 RGD:2312309 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24535859 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sirt3 sirtuin 3 ISO protein:decreased expression:heart left ventricle RGD PMID:22155497 RGD:9586040 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222 		JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 treatment ISO RGD PMID:22796714 RGD:401901592 NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 severity ISO protein:decreased expression:skeletal muscle RGD PMID:18778861 RGD:2313624 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 ISO DNA:repeat:promoter (human) RGD PMID:17307423 RGD:4889438 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166 		JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 ISO protein:increased expression:cardiac muscle cell RGD PMID:17536604 RGD:1642720 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19027022 PMID:18776042 RGD:6771337 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A disease_progression ISO DNA:mutations: : RGD PMID:33779075 RGD:155630627 NCBI chr  X:150,799,386...150,844,969
Ensembl chr  X:150,799,424...150,845,690 		JBrowse link
G Snca synuclein, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839 		JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO
IAGP		 CTD Direct Evidence: marker/mechanism CTD
MouseDO		 PMID:16105639 PMID:16155095 PMID:20304815 PMID:21195081 PMID:21284947 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760 		JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 ISO RGD PMID:34321385 RGD:155882552 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610 		JBrowse link
G Sox2ot SOX2 overlapping transcript (non-protein coding) severity ISO CTD Direct Evidence: marker/mechanism
associated with ischemic cardiomyopathy; RNA:increased expression:heart left ventricle (human)		 CTD
RGD		 PMID:27317124 PMID:36071497 RGD:243048444 NCBI chr 3:34,614,530...34,732,142
Ensembl chr 3:34,158,419...34,736,768 		JBrowse link
G Sox4 SRY (sex determining region Y)-box 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr13:29,132,902...29,137,682
Ensembl chr13:29,132,902...29,137,696 		JBrowse link
G Sphkap SPHK1 interactor, AKAP domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 1:83,233,163...83,385,853
Ensembl chr 1:83,231,860...83,385,921 		JBrowse link
G Sra1 steroid receptor RNA activator 1 severity ISO associated with ischemic cardiomyopathy; RNA:increased expression:heart left ventricle (human) RGD PMID:27317124 RGD:243048444 NCBI chr18:36,800,240...36,803,364
Ensembl chr18:36,799,734...36,803,868 		JBrowse link
G Srf serum response factor ISO mRNA, protein:splice variant:heart RGD PMID:11893590 RGD:1581426 NCBI chr17:46,857,764...46,869,194
Ensembl chr17:46,859,255...46,867,101 		JBrowse link
G Sri sorcin ISO protein:decreased expression:cardiac muscle cell
associated with Hypertension		 RGD PMID:20945956 PMID:12754254 RGD:7327198, RGD:7327200 NCBI chr 5:8,096,078...8,119,314
Ensembl chr 5:8,096,078...8,119,379 		JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 disease_progression ISO DNA:mutations: : RGD PMID:33779075 RGD:155630627 NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tbx20 T-box 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 9:24,632,108...24,685,580
Ensembl chr 9:24,629,434...24,685,599 		JBrowse link
G Th tyrosine hydroxylase ISO
IMP		 protein:increased expression:paraventricular thalamic nucleus (rat) RGD PMID:21287352 PMID:7715703 RGD:5128674, RGD:737737 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 ISO protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 ISO protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566 		JBrowse link
G Timp4 tissue inhibitor of metalloproteinase 4 ISO protein:decreased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr 6:115,221,405...115,229,166
Ensembl chr 6:115,218,853...115,229,166 		JBrowse link
G Tlr2 toll-like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tmem71 transmembrane protein 71 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr15:66,398,061...66,433,085
Ensembl chr15:66,398,061...66,432,952 		JBrowse link
G Tnf tumor necrosis factor treatment
severity		 ISO
IAGP		 CTD Direct Evidence: marker/mechanism
associated with Myocardial Infarction;		 MouseDO
CTD
RGD		 PMID:15135663 PMID:15231041 PMID:17337591 PMID:18034274 PMID:29959987 More... RGD:1580213, RGD:14975271, RGD:7401242, RGD:7401241 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) ISO mRNA, protein:incereased expression:myocardium RGD PMID:15883214 RGD:1624176 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO human protein in rat model RGD PMID:21135513 RGD:5131262 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tnnt2 troponin T2, cardiac ISO CTD Direct Evidence: marker/mechanism CTD PMID:12322705 PMID:17698733 NCBI chr 1:135,763,933...135,780,006
Ensembl chr 1:135,764,092...135,779,998 		JBrowse link
G Tomm70a translocase of outer mitochondrial membrane 70A ISO mRNA:decreased expression:heart
protein:increased serine phosphorylation:heart, mitochondrion		 RGD PMID:25022898 PMID:24395194 RGD:13464131, RGD:13464132 NCBI chr16:56,942,077...56,974,893
Ensembl chr16:56,942,066...56,977,068 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment ISO RGD PMID:33495812 RGD:127229929 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Trp53 transformation related protein 53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33594499 NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204 		JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Congestive heart failure | ClinVar Annotator: match by term: Heart failure ClinVar PMID:15802564 PMID:17344846 PMID:23396983 PMID:23486992 PMID:23861362 More... NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891 		JBrowse link
G Ttr transthyretin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:1355416 PMID:1850190 PMID:1997217 PMID:2174830 PMID:2590199 More... NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Tubb5 tubulin, beta 5 class I EXP CTD Direct Evidence: marker/mechanism CTD PMID:16155095 NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198 		JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Ucn urocortin ISO protein:increased secretion:plasma (human) RGD PMID:19808377 RGD:5490589 NCBI chr 5:31,295,333...31,296,239
Ensembl chr 5:31,295,407...31,296,173 		JBrowse link
G Ucn2 urocortin 2 ISO mRNA, protein:increased expression:myocardium (human)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:16330704 PMID:12076554 RGD:5508210 NCBI chr 9:108,815,231...108,816,232
Ensembl chr 9:108,815,078...108,816,232 		JBrowse link
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 8:84,016,977...84,025,085
Ensembl chr 8:84,016,981...84,025,081 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) ISO protein:decreased expression:heart, mitochondria RGD PMID:20809120 PMID:20193183 RGD:7204424, RGD:7204426 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) ISO protein:decreased expression:heart, mitochondria RGD PMID:20809120 RGD:7204424 NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639 		JBrowse link
G Uts2 urotensin 2 severity ISO protein:increased expression:plasma RGD PMID:16364499 PMID:12791592 RGD:2306804, RGD:1580809 NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267 		JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:24033266 PMID:25741868 PMID:28492532 PMID:33500567 NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15732037 PMID:15880336 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vwf Von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
G Xaf1 XIAP associated factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559 		JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19933411 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Yy1 YY1 transcription factor ISO RGD PMID:12754214 RGD:1580831 NCBI chr12:108,758,841...108,786,074
Ensembl chr12:108,758,899...108,786,074 		JBrowse link
G Zeb2os zinc finger E-box binding homeobox 2, opposite strand ISO CTD Direct Evidence: marker/mechanism CTD PMID:36071497 NCBI chr 2:45,001,150...45,004,099
Ensembl chr 2:45,000,719...45,004,099 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 exacerbates IDA RGD PMID:18658259 RGD:155882484 NCBI chr15:40,518,438...40,967,988
Ensembl chr15:40,518,431...40,967,988 		JBrowse link
Alcohol-Induced Sudden Cardiac Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 pyrophosphatase (inorganic) 2 ISO ClinVar Annotator: match by term: Sudden cardiac failure, alcohol-induced OMIM
ClinVar		 PMID:24033266 PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 More... NCBI chr 3:133,015,842...133,083,996
Ensembl chr 3:133,015,871...133,083,996 		JBrowse link
cardiac arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 treatment ISO RGD PMID:26010685 RGD:12791997 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr 5:3,977,410...4,130,204
Ensembl chr 5:3,978,054...4,131,310 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 IMP RGD PMID:20363892 RGD:5509101 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Ank2 ankyrin 2, brain ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 PMID:28600387 PMID:36413997 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999 		JBrowse link
G Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:20817017 PMID:21383000 PMID:22840528 PMID:25527503 PMID:25741868 More... NCBI chr 5:16,139,390...16,579,509
Ensembl chr 5:16,139,786...16,579,502 		JBrowse link
G Cacnb2 calcium channel, voltage-dependent, beta 2 subunit ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 PMID:28600387 NCBI chr 2:14,608,672...14,993,622
Ensembl chr 2:14,607,899...14,992,719 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:hippocampus (rat) RGD PMID:19756023 RGD:4889980 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cep85l centrosomal protein 85-like ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 More... NCBI chr10:53,149,537...53,256,765
Ensembl chr10:53,149,539...53,256,043 		JBrowse link
G Dpp6 dipeptidylpeptidase 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr 5:27,022,355...27,932,498
Ensembl chr 5:27,022,201...27,932,503 		JBrowse link
G Dsc2 desmocollin 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:18678517 PMID:23861362 PMID:24033266 PMID:24704780 PMID:25637381 More... NCBI chr18:20,163,690...20,192,611
Ensembl chr18:20,163,690...20,192,611 		JBrowse link
G Dsg2 desmoglein 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:20400443 PMID:23861362 PMID:24070718 PMID:25741868 PMID:28492532 More... NCBI chr18:20,691,247...20,737,583
Ensembl chr18:20,691,131...20,737,578 		JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:20716751 PMID:21606390 PMID:22240500 PMID:24503780 PMID:25227139 More... NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO RGD PMID:9522364 RGD:13208524 NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058 		JBrowse link
G Ep300 E1A binding protein p300 ISO associated with Diabetes Mellitus; mRNA:increased expression:blood (human) RGD PMID:19577077 RGD:2312286 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic IMP RGD PMID:17728042 RGD:5688386 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Gas5 growth arrest specific 5 ameliorates ISO RNA:increased expression:hippocampus, cortex; RGD PMID:30824348 PMID:30824348 RGD:155882547, RGD:155882547 NCBI chr 1:160,862,171...160,866,109
Ensembl chr 1:160,861,992...160,866,116 		JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:58,730,232...58,770,458
Ensembl chr 9:58,730,695...58,770,458 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:9806674 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:18679114 RGD:4889454 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: therapeutic CTD PMID:17449947 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 ISO protein:increased expression:cerebellum (rat) RGD PMID:21859719 RGD:6480675 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532 NCBI chr 6:142,510,563...142,517,340
Ensembl chr 6:142,510,563...142,517,340 		JBrowse link
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 ISO CTD Direct Evidence: therapeutic CTD PMID:33887967 NCBI chr18:45,401,754...45,818,954
Ensembl chr18:45,401,927...45,818,950 		JBrowse link
G Mir23a microRNA 23a ISO RNA:decreased expression:hippocampus, cortex; RGD PMID:30824348 RGD:155882547 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Mybpc3 myosin binding protein C, cardiac ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:14563344 PMID:15519027 PMID:16352453 PMID:20624503 PMID:22361390 More... NCBI chr 2:90,948,459...90,966,862
Ensembl chr 2:90,948,489...90,966,861 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr17:71,326,455...71,433,851
Ensembl chr17:71,309,628...71,433,851 		JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 More... NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:22004663 PMID:24033266 PMID:24503780 PMID:25637381 PMID:25741868 More... NCBI chr19:53,649,422...53,855,514
Ensembl chr19:53,665,737...53,855,511 		JBrowse link
G Ryr2 ryanodine receptor 2, cardiac ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831 		JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12354768 PMID:12820704 PMID:15466642 PMID:15840476 PMID:16540748 More... NCBI chr 9:119,312,470...119,408,096
Ensembl chr 9:119,312,474...119,408,082 		JBrowse link
G Slmap sarcolemma associated protein ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr14:26,134,323...26,256,103
Ensembl chr14:26,134,323...26,256,086 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IDA RGD PMID:15843790 RGD:1581221 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9806674 PMID:18679114 RGD:4889454 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 treatment ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar
RGD		 PMID:28492532 PMID:26010685 RGD:12791997 NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204 		JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744 		JBrowse link
Cardiac Edema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22865611 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540 		JBrowse link
G Ift122 intraflagellar transport 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20493458 NCBI chr 6:115,830,340...115,903,660
Ensembl chr 6:115,830,431...115,903,660 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23533172 NCBI chr 4:148,518,952...148,529,217
Ensembl chr 4:148,518,952...148,529,228 		JBrowse link
Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO protein:increased expression:kidney tubule: RGD PMID:23220287 PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Mir21a microRNA 21a ameliorates ISO RGD PMID:28760335 RGD:41410821 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Myocd myocardin ameliorates ISO mRNA,protein:increased expression:left ventricle RGD PMID:30971740 PMID:30971740 RGD:401793740, RGD:401793740 NCBI chr11:65,064,434...65,160,821
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
Cor pulmonale term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21450080 RGD:6767563 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:20669672 RGD:4143386 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Il27 interleukin 27 disease_progression ISO associated with hand, foot and mouth disease;protein:altered expression:blood��serum (human) RGD PMID:27403033 RGD:126790503 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:20669672 RGD:4143386 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
diastolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme severity
treatment
susceptibility		 ISO DNS:insertion/deletion:intron: (rs1799752)
DNA:insertion/deletion:intron 16:		 RGD PMID:19752885 PMID:14757777 PMID:19021695 RGD:40400704, RGD:40400723, RGD:40400906 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Adra1d adrenergic receptor, alpha 1d ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 2:131,387,277...131,404,417
Ensembl chr 2:131,387,770...131,404,203 		JBrowse link
G Akip1 A kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:109,302,885...109,311,393
Ensembl chr 7:109,302,897...109,311,396 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:36,569,269...36,578,380
Ensembl chr 1:36,569,269...36,575,964
Ensembl chr 1:36,569,269...36,575,964 		JBrowse link
G Apln apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:47,114,023...47,123,730
Ensembl chr  X:47,114,023...47,123,730 		JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 2:131,028,356...131,040,431
Ensembl chr 2:131,028,869...131,040,417 		JBrowse link
G Col4a1 collagen, type IV, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Col6a1 collagen, type VI, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002 		JBrowse link
G Col8a1 collagen, type VIII, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr16:57,444,619...57,575,100
Ensembl chr16:57,444,621...57,575,100 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:165,591,327...165,602,878
Ensembl chr 1:165,591,315...165,602,877 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr15:63,800,943...63,932,627
Ensembl chr15:63,800,946...63,932,327 		JBrowse link
G Elk3 ELK3, member of ETS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:93,083,277...93,147,021
Ensembl chr10:93,083,276...93,146,997 		JBrowse link
G Epn3 epsin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:94,380,425...94,390,800
Ensembl chr11:94,380,425...94,390,800 		JBrowse link
G Fhl1 four and a half LIM domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706 		JBrowse link
G Fibin fin bud initiation factor homolog (zebrafish) ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 2:110,191,270...110,193,338
Ensembl chr 2:110,191,262...110,193,528 		JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:30,769,960...30,776,122
Ensembl chr 7:30,767,597...30,776,129 		JBrowse link
G Hamp hepcidin antimicrobial peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457 		JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 9:21,678,069...21,709,842
Ensembl chr 9:21,678,080...21,710,040 		JBrowse link
G Klf9 Kruppel-like transcription factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr19:23,118,590...23,145,493
Ensembl chr19:23,118,590...23,145,498 		JBrowse link
G Lepr leptin receptor treatment ISO DNA:mutations:cds: : (rat) RGD PMID:33568522 RGD:401965412 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr19:11,446,718...11,464,433
Ensembl chr19:11,446,730...11,459,556 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Nppa natriuretic peptide precursor type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nupr1 nuclear protein transcription regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:3,280,731...3,292,971
Ensembl chr11:3,280,401...3,292,971 		JBrowse link
G Plxnd1 plexin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 6:115,931,772...115,972,300
Ensembl chr 6:115,931,772...115,971,966 		JBrowse link
G Ptp4a2 protein tyrosine phosphatase 4a2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:129,704,982...129,743,800
Ensembl chr 4:129,705,012...129,743,796 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:57,190,841...57,339,036
Ensembl chr 4:57,190,841...57,301,837 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648 		JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr12:82,216,138...82,498,560
Ensembl chr12:82,216,094...82,498,560 		JBrowse link
G Trdn triadin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:32,959,479...33,352,705
Ensembl chr10:32,956,550...33,352,705 		JBrowse link
G Wdr45 WD repeat domain 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:7,588,212...7,594,439
Ensembl chr  X:7,580,572...7,594,445 		JBrowse link
G Zfp532 zinc finger protein 532 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr18:65,713,301...65,822,514
Ensembl chr18:65,712,983...65,822,514 		JBrowse link
Neonatal Pulmonary Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cps1 carbamoyl-phosphate synthetase 1 susceptibility ISO ClinVar Annotator: match by term: Pulmonary hypertension, neonatal, susceptibility to ClinVar
OMIM		 PMID:8486760 PMID:9536098 PMID:9686343 PMID:9711878 PMID:11388595 More... NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418 		JBrowse link
Paroxysmal Dyspnea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:21388992 RGD:5129099 NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,963...134,163,169 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO ClinVar Annotator: match by term: Asthma, nocturnal, susceptibility to ClinVar PMID:7706471 PMID:9399946 PMID:9399966 PMID:9522789 PMID:11739457 More... NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
primary pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,444,927...60,521,104
Ensembl chr 1:60,448,778...60,520,317 		JBrowse link
G Acadl acyl-Coenzyme A dehydrogenase, long-chain ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436 		JBrowse link
G Acvrl1 activin A receptor, type II-like 1 ISO ClinVar Annotator: match by term: Heritable pulmonary arterial hypertension ClinVar PMID:25741868 PMID:28492532 PMID:31727138 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Adam23 a disintegrin and metallopeptidase domain 23 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,484,880...63,635,263
Ensembl chr 1:63,485,050...63,635,435 		JBrowse link
G Adora2a adenosine A2a receptor IAGP OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618 		JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 1:59,201,915...59,276,390
Ensembl chr 1:59,202,085...59,276,390 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor, type 1B ISO ClinVar Annotator: match by term: Idiopathic pulmonary arterial hypertension ClinVar PMID:22374147 PMID:25741868 PMID:25758993 PMID:28492532 NCBI chr 3:141,540,230...141,875,335
Ensembl chr 3:141,542,897...141,875,186 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension | ClinVar Annotator: match by term: Primary pulmonary hypertension | ClinVar Annotator: match by term: Pulmonary hypertension, primary, dexfenfluramine-associated | ClinVar Annotator: match by term: Pulmonary hypertension, primary, fenfluramine-associated
OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344		 CTD
ClinVar
MouseDO		 PMID:3291115 PMID:9536098 PMID:10903931 PMID:10973254 PMID:11015450 More... NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173 		JBrowse link
G Carf calcium response factor ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,137,380...60,193,112
Ensembl chr 1:60,137,406...60,193,112 		JBrowse link
G Cav1 caveolin 1, caveolae protein ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Ccnyl1 cyclin Y-like 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:64,729,963...64,764,805
Ensembl chr 1:64,729,614...64,764,803 		JBrowse link
G Cd28 CD28 antigen ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cdk15 cyclin dependent kinase 15 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 1:59,296,029...59,391,656
Ensembl chr 1:59,296,065...59,392,152 		JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,221,737...63,253,714
Ensembl chr 1:63,221,850...63,253,702 		JBrowse link
G Cps1 carbamoyl-phosphate synthetase 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707 		JBrowse link
G Cryga crystallin, gamma A ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,139,552...65,142,532
Ensembl chr 1:65,139,548...65,142,532 		JBrowse link
G Crygb crystallin, gamma B ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,119,381...65,121,449
Ensembl chr 1:65,119,378...65,121,447 		JBrowse link
G Crygc crystallin, gamma C ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,110,684...65,112,691
Ensembl chr 1:65,110,684...65,112,848 		JBrowse link
G Crygd crystallin, gamma D ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,101,001...65,102,598
Ensembl chr 1:65,101,031...65,102,611 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Cyp20a1 cytochrome P450, family 20, subfamily a, polypeptide 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,382,459...60,427,219
Ensembl chr 1:60,382,482...60,427,219 		JBrowse link
G D630023F18Rik RIKEN cDNA D630023F18 gene ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,144,443...65,162,509
Ensembl chr 1:65,144,444...65,162,373 		JBrowse link
G Dytn dystrotelin ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,662,010...63,726,086
Ensembl chr 1:63,662,010...63,726,086 		JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,215,990...63,219,645
Ensembl chr 1:63,215,984...63,219,645 		JBrowse link
G Fam117b family with sequence similarity 117, member B ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:59,952,165...60,024,507
Ensembl chr 1:59,952,165...60,024,505 		JBrowse link
G Fastkd2 FAST kinase domains 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,769,758...63,792,544
Ensembl chr 1:63,769,773...63,793,814 		JBrowse link
G Fbxo32 F-box protein 32 ISO mRNA:increased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO protein:increased expression:lung (human) RGD PMID:29722558 RGD:155791445 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Foxf1 forkhead box F1 ISO ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension ClinVar PMID:19500772 PMID:19592680 PMID:19812545 PMID:20425831 PMID:22766610 More... NCBI chr 8:121,811,100...121,814,883
Ensembl chr 8:121,811,125...121,814,883 		JBrowse link
G Fzd5 frizzled class receptor 5 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910 		JBrowse link
G Fzd7 frizzled class receptor 7 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114 		JBrowse link
G Gm13754 predicted gene 13754 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,957,040...63,973,947
Ensembl chr 1:63,957,007...63,975,091 		JBrowse link
G Hdac1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421 		JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992 		JBrowse link
G Ica1l islet cell autoantigen 1-like ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,024,955...60,082,646
Ensembl chr 1:60,021,649...60,082,343 		JBrowse link
G Icos inducible T cell co-stimulator ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO protein:decreased expression:lung, wall of arteriole (human) RGD PMID:20522807 RGD:9686087 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Idh1 isocitrate dehydrogenase 1 (NADP+), soluble ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,197,775...65,225,638
Ensembl chr 1:65,197,775...65,225,659 		JBrowse link
G Ino80d INO80 complex subunit D ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,086,960...63,153,693
Ensembl chr 1:62,997,577...63,153,849 		JBrowse link
G Kansl1l KAT8 regulatory NSL complex subunit 1-like ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:66,758,402...66,856,754
Ensembl chr 1:66,758,407...66,856,721 		JBrowse link
G Kcnk3 potassium channel, subfamily K, member 3 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 5:30,745,514...30,782,614
Ensembl chr 5:30,745,514...30,782,615 		JBrowse link
G Klf7 Kruppel-like transcription factor 7 (ubiquitous) ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:64,068,607...64,161,504
Ensembl chr 1:64,068,606...64,161,441 		JBrowse link
G Lancl1 LanC (bacterial lantibiotic synthetase component C)-like 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:67,039,676...67,078,049
Ensembl chr 1:67,039,676...67,078,031 		JBrowse link
G Map2 microtubule-associated protein 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742 		JBrowse link
G Mdh1b malate dehydrogenase 1B, NAD (soluble) ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,726,732...63,769,707
Ensembl chr 1:63,737,978...63,769,477 		JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:64,645,632...64,661,926
Ensembl chr 1:64,645,632...64,656,401 		JBrowse link
G Mfn1 mitofusin 1 ISO protein:decreased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388 		JBrowse link
G Mfn2 mitofusin 2 ISO protein:decreased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Mir23a microRNA 23a ISO RNA:increased expression:serum RGD PMID:25815108 RGD:155882560 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Myl1 myosin, light polypeptide 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:66,963,454...66,987,091
Ensembl chr 1:66,963,454...66,984,563 		JBrowse link
G Nbeal1 neurobeachin like 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,217,910...60,377,487
Ensembl chr 1:60,219,758...60,377,487 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,182,751...63,215,981
Ensembl chr 1:63,182,755...63,215,992 		JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 1:59,724,165...59,751,352
Ensembl chr 1:59,724,130...59,758,203 		JBrowse link
G Nrp2 neuropilin 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854 		JBrowse link
G Pard3b par-3 family cell polarity regulator beta ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:61,677,825...62,681,443
Ensembl chr 1:61,677,983...62,681,443 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,225,796...65,317,855
Ensembl chr 1:65,225,842...65,317,854 		JBrowse link
G Plekhm3 pleckstrin homology domain containing, family M, member 3 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:64,828,279...64,995,983
Ensembl chr 1:64,825,142...64,995,983 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma IAGP OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase ISO DNA:SNP, missense mutations:intron 4, CDS:c.521+1G>A, p.R252Q (c.755G>A), p.A447T (c.1339G>A) (, rs759344518, rs146531327) (human) RGD PMID:32236489 RGD:401901150 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
G Pth2r parathyroid hormone 2 receptor ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:65,317,921...65,428,784
Ensembl chr 1:65,321,215...65,428,403 		JBrowse link
G Raph1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,509,997...60,606,233
Ensembl chr 1:60,521,451...60,606,263 		JBrowse link
G Rfc1 replication factor C (activator 1) 1 ISO mRNA:increased expression:lung (human) RGD PMID:37410515 RGD:401940160 NCBI chr 5:65,419,195...65,492,988
Ensembl chr 5:65,419,193...65,493,013 		JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:66,739,957...66,758,964
Ensembl chr 1:66,739,990...66,758,964 		JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle ISO protein:increased phosphorylation:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604 		JBrowse link
G Smad9 SMAD family member 9 ISO
IAGP		 CTD Direct Evidence: marker/mechanism
OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344		 CTD
MouseDO		 NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678 		JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 ISO protein:decreased expression:pulmonary artery (human) RGD PMID:36919784 RGD:329853737 NCBI chr 1:4,561,154...4,567,624
Ensembl chr 1:4,561,154...4,567,577 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993 		JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 IAGP OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981 		JBrowse link
G Trim63 tripartite motif-containing 63 ISO mRNA, protein:increased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 4:134,042,431...134,056,940
Ensembl chr 4:134,042,431...134,056,940 		JBrowse link
G Unc80 unc-80, NALCN activator ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:66,507,093...66,738,309
Ensembl chr 1:66,507,526...66,738,307 		JBrowse link
G Vip vasoactive intestinal polypeptide IAGP OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617 		JBrowse link
G Wdr12 WD repeat domain 12 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:60,110,520...60,137,659
Ensembl chr 1:60,108,944...60,137,804 		JBrowse link
G Zdbf2 zinc finger, DBF-type containing 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 1:63,239,517...63,353,735
Ensembl chr 1:63,312,424...63,353,735 		JBrowse link
primary pulmonary hypertension 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:9245985 PMID:12700602 PMID:14684682 PMID:15024723 PMID:15879500 More... NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO ClinVar Annotator: match by term: BMPR2-related disorder | ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 | ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia OMIM
ClinVar		 PMID:3291115 PMID:9536098 PMID:10903931 PMID:10973254 PMID:11015450 More... NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173 		JBrowse link
G Eng endoglin ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:16690726 PMID:16754821 PMID:18498373 PMID:23298310 PMID:24033266 More... NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Gm26287 predicted gene, 26287 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 1:59,743,417...59,743,497
Ensembl chr 1:59,743,417...59,743,497 		JBrowse link
G Gm26293 predicted gene, 26293 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 1:59,731,668...59,731,751
Ensembl chr 1:59,731,668...59,731,751 		JBrowse link
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:20018952 PMID:21685056 PMID:23861362 PMID:24068186 PMID:25076992 More... NCBI chr 6:126,509,514...126,512,518
Ensembl chr 6:126,509,514...126,512,375 		JBrowse link
G Kcnk3 potassium channel, subfamily K, member 3 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23883380 NCBI chr 5:30,745,514...30,782,614
Ensembl chr 5:30,745,514...30,782,615 		JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 1:59,724,165...59,751,352
Ensembl chr 1:59,724,130...59,758,203 		JBrowse link
G Pah phenylalanine hydroxylase ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:1301187 PMID:1682234 PMID:1769645 PMID:2044609 PMID:2574153 More... NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998 		JBrowse link
G Smad1 SMAD family member 1 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:21898662 NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:21898662 PMID:24728327 PMID:25502805 PMID:25741868 PMID:28492532 More... NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678 		JBrowse link
G Snord11 small nucleolar RNA, C/D box 11 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 1:59,743,967...59,744,029
Ensembl chr 1:59,743,949...59,744,032 		JBrowse link
G Snord70 small nucleolar RNA, C/D box 70 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 1:59,731,117...59,731,169
Ensembl chr 1:59,731,093...59,731,179 		JBrowse link
G Tbx4 T-box 4 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:9536098 PMID:15106123 PMID:16199547 PMID:17576681 PMID:23592887 More... NCBI chr11:85,777,193...85,806,923
Ensembl chr11:85,777,248...85,806,923 		JBrowse link
primary pulmonary hypertension 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 2 OMIM
ClinVar		 PMID:9536098 PMID:16199547 PMID:17576681 PMID:19211612 PMID:19419974 More... NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678 		JBrowse link
primary pulmonary hypertension 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor, type 1B ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 3 ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:141,540,230...141,875,335
Ensembl chr 3:141,542,897...141,875,186 		JBrowse link
G Cav1 caveolin 1, caveolae protein ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 3 OMIM
ClinVar		 PMID:22474227 PMID:25741868 PMID:28492532 PMID:29231014 PMID:31727138 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
primary pulmonary hypertension 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium channel, subfamily K, member 3 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 4 OMIM
ClinVar		 PMID:9536098 PMID:17576681 PMID:23883380 PMID:24033266 PMID:25741868 More... NCBI chr 5:30,745,514...30,782,614
Ensembl chr 5:30,745,514...30,782,615 		JBrowse link
primary pulmonary hypertension 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a3 ATPase type 13A3 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, autosomal recessive OMIM
ClinVar		 PMID:25741868 PMID:28492532 PMID:30679663 PMID:31727138 PMID:34493544 More... NCBI chr16:30,131,241...30,207,674
Ensembl chr16:30,131,241...30,224,793 		JBrowse link
primary pulmonary hypertension 6 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capns1 calpain, small subunit 1 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 6 ClinVar
OMIM		 PMID:21972389 PMID:38230350 NCBI chr 7:29,886,359...29,898,308
Ensembl chr 7:29,886,361...29,898,236 		JBrowse link
Sudden Cardiac Death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 disease_progression ISO RGD PMID:22661490 RGD:13831296 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460 		JBrowse link
G Adra2b adrenergic receptor, alpha 2b ISO RGD PMID:12535806 RGD:1559314 NCBI chr 2:127,205,099...127,209,141
Ensembl chr 2:127,205,128...127,209,141 		JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr 5:3,977,410...4,130,204
Ensembl chr 5:3,978,054...4,131,310 		JBrowse link
G Ank2 ankyrin 2, brain ISO ClinVar Annotator: match by term: Sudden cardiac arrest | ClinVar Annotator: match by term: Sudden cardiac death ClinVar
RGD		 PMID:25741868 PMID:28492532 PMID:12571597 RGD:734572 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999 		JBrowse link
G Apob apolipoprotein B ISO RGD PMID:17045270 RGD:1601197 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851 		JBrowse link
G Cep85l centrosomal protein 85-like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 More... NCBI chr10:53,149,537...53,256,765
Ensembl chr10:53,149,539...53,256,043 		JBrowse link
G Dpp6 dipeptidylpeptidase 6 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 5:27,022,355...27,932,498
Ensembl chr 5:27,022,201...27,932,503 		JBrowse link
G Dsg2 desmoglein 2 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chr18:20,691,247...20,737,583
Ensembl chr18:20,691,131...20,737,578 		JBrowse link
G Dsp desmoplakin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20435227 NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553 		JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP RGD PMID:22093512 RGD:12910124 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362 PMID:25741868 PMID:27930701 PMID:28492532 NCBI chr 9:114,728,407...114,763,055
Ensembl chr 9:114,728,409...114,763,055 		JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:21615589 PMID:23623143 PMID:23861362 PMID:24033266 PMID:25145517 More... NCBI chr 9:58,730,232...58,770,458
Ensembl chr 9:58,730,695...58,770,458 		JBrowse link
G Il6 interleukin 6 susceptibility ISO RGD PMID:23906927 RGD:12792237 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itgb3 integrin beta 3 ISO associated with arteriosclerosis; DNA:polymorphism:exon RGD PMID:20846430 RGD:5128476 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 ISO ClinVar Annotator: match by term: Sudden cardiac arrest | ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:18508782 PMID:19716085 PMID:22581653 PMID:25417810 PMID:25741868 More... NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602 		JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chr 7:142,660,614...142,980,787
Ensembl chr 7:142,660,099...142,980,779 		JBrowse link
G Kcnq1ot1 KCNQ1 overlapping transcript 1 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chr 7:142,766,848...142,850,284
Ensembl chr 7:142,731,562...142,850,286 		JBrowse link
G Kng1 kininogen 1 susceptibility ISO DNA:SNPs: : RGD PMID:19716087 RGD:10411885 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Kng2 kininogen 2 susceptibility ISO DNA:SNPs: : RGD PMID:19716087 RGD:10411885 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232 		JBrowse link
G Lmna lamin A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Family history of sudden cardiac death		 CTD
ClinVar		 PMID:15996213 PMID:17711925 PMID:24623722 PMID:25741868 PMID:28492532 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263 		JBrowse link
G mt-Tt tRNA threonine, mitochondrial ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:1379415 PMID:1645537 PMID:8511015 PMID:22638997 PMID:25741868 More... NCBI chr MT:15,289...15,355
Ensembl chr MT:15,289...15,355 		JBrowse link
G Mybpc3 myosin binding protein C, cardiac ISO CTD Direct Evidence: marker/mechanism CTD PMID:20435227 NCBI chr 2:90,948,459...90,966,862
Ensembl chr 2:90,948,489...90,966,861 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24033266 PMID:28492532 NCBI chr17:71,326,455...71,433,851
Ensembl chr17:71,309,628...71,433,851 		JBrowse link
G Nebl nebulette ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 2:17,347,484...17,740,634
Ensembl chr 2:17,348,720...17,736,275 		JBrowse link
G Pkp2 plakophilin 2 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 PMID:27532257 PMID:28492532 PMID:29802319 PMID:31402444 NCBI chr16:16,031,209...16,090,576
Ensembl chr16:16,031,182...16,090,576 		JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 More... NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
G Ryr2 ryanodine receptor 2, cardiac ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac arrest | ClinVar Annotator: match by term: Sudden cardiac death		 CTD
ClinVar		 PMID:12459180 PMID:22787013 PMID:23861362 PMID:24033266 PMID:25650408 More... NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831 		JBrowse link
G Scn3b sodium channel, voltage-gated, type III, beta ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 9:40,180,512...40,202,914
Ensembl chr 9:40,180,513...40,202,914 		JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO ClinVar Annotator: match by term: Sudden cardiac arrest | ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:14985827 PMID:15851227 PMID:16712702 PMID:18378609 PMID:18508782 More... NCBI chr 9:119,312,470...119,408,096
Ensembl chr 9:119,312,474...119,408,082 		JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 ISO ClinVar Annotator: match by term: Family history of sudden cardiac death ClinVar PMID:25741868 PMID:28492532 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321 		JBrowse link
G Sp4 trans-acting transcription factor 4 IAGP RGD PMID:11007485 RGD:1580019 NCBI chr12:118,195,421...118,265,211
Ensembl chr12:118,198,668...118,265,175 		JBrowse link
G Tmem43 transmembrane protein 43 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac arrest		 CTD
ClinVar		 PMID:20435227 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 6:91,450,689...91,465,445
Ensembl chr 6:91,450,685...91,465,445 		JBrowse link
G Tnni3 troponin I, cardiac 3 ISO ClinVar Annotator: match by term: Sudden cardiac arrest ClinVar PMID:21839045 PMID:25741868 NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228 		JBrowse link
G Tnnt2 troponin T2, cardiac ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death		 CTD
ClinVar		 PMID:17556660 PMID:23233322 PMID:24033266 PMID:24503780 PMID:25741868 More... NCBI chr 1:135,763,933...135,780,006
Ensembl chr 1:135,764,092...135,779,998 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 ISO ClinVar Annotator: match by term: Family history of sudden cardiac death | ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:20562447 PMID:21887725 PMID:23382873 PMID:24019741 PMID:25416190 More... NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204 		JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Sudden cardiac arrest | ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:19608031 PMID:24033266 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891 		JBrowse link
Sudden Cardiac Failure, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 pyrophosphatase (inorganic) 2 ISO ClinVar Annotator: match by term: PPA2-Related Disorders | ClinVar Annotator: match by term: Sudden cardiac failure, infantile OMIM
ClinVar		 PMID:24033266 PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 More... NCBI chr 3:133,015,842...133,083,996
Ensembl chr 3:133,015,871...133,083,996 		JBrowse link
systolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 ISO ClinVar Annotator: match by term: Systolic heart failure ClinVar PMID:19525294 PMID:23299917 PMID:23861362 PMID:24033266 PMID:25741868 More... NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499 		JBrowse link
G Bmp10 bone morphogenetic protein 10 ISO CTD Direct Evidence: therapeutic CTD PMID:31712309 NCBI chr 6:87,405,976...87,411,494
Ensembl chr 6:87,405,976...87,414,659 		JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Systolic heart failure ClinVar PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553 		JBrowse link
G Hspa1a heat shock protein 1A disease_progression ISO protein:increased expression:serum: RGD PMID:23564583 RGD:7257646 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Nppb natriuretic peptide type B ISO associated with Renal Insufficiency;protein:increased expression:plasma: RGD PMID:23725445 PMID:23122795 RGD:7246908, RGD:7247627 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Systolic heart failure ClinVar PMID:23861362 PMID:24033266 PMID:25163546 PMID:25741868 PMID:26467025 More... NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16193
    disease of anatomical entity 15759
      cardiovascular system disease 4717
        heart disease 3331
          congestive heart failure 565
            Cardiac Edema 3
            Cardio-Renal Syndrome 3
            Cor pulmonale + 91
            Paroxysmal Dyspnea 2
            cardiac arrest + 62
            diastolic heart failure 35
            rheumatic congestive heart failure 0
            systolic heart failure 6
paths to the root