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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:congestive heart failure
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Accession:DOID:6000 term browser browse the term
Definition:A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Synonyms:exact_synonym: CHF;   Cardiac Failure;   Cardiac Failure Congestive;   Congestive heart disease;   Heart Decompensation;   Heart Failure;   Left Sided Heart Failure;   Myocardial Failure;   Right Sided Heart Failure;   Weak heart
 narrow_synonym: Chronic Heart Failure
 related_synonym: Beta-2-adrenoreceptor agonist, reduced response to;   Congestive heart failure and beta-blocker response, modifier of;   Congestive heart failure, modifier of
 primary_id: MESH:D006333;   RDO:0005421
 xref: ICD10CM:I50;   ICD10CM:I50.9;   ICD9CM:428;   ICD9CM:428.0;   NCI:C3080;   NCI:C50577
For additional species annotation, visit the Alliance of Genome Resources.


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congestive heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1b acetyl-Coenzyme A acyltransferase 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 9:119,148,043...119,157,093
Ensembl chr 9:119,148,023...119,157,093
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr11:84,129,635...84,401,651
Ensembl chr11:84,129,672...84,401,651
JBrowse link
G Acads acyl-Coenzyme A dehydrogenase, short chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30827304 NCBI chr 5:115,110,299...115,119,346
Ensembl chr 5:115,110,299...115,119,346
JBrowse link
G Acan aggrecan ISO mRNA:increased expression:myocardium RGD PMID:24595230 RGD:11570548 NCBI chr 7:79,053,226...79,115,099
Ensembl chr 7:79,053,483...79,115,099
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 treatment ISO associated with Myocardial Infarction
CTD Direct Evidence: marker/mechanism
associated with Hypertension
CTD PMID:18586661, PMID:19620082, PMID:15894569, PMID:22123369 RGD:2325224, RGD:12859272, RGD:6893472 NCBI chr11:105,967,948...105,989,964
Ensembl chr11:105,967,945...105,989,964
JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 IEA
ISO
mRNA, protein:increased expression:heart (human)
CTD Direct Evidence: marker/mechanism
MouseDO
CTD
PMID:25973029, PMID:32227090 RGD:40818416 NCBI chr  X:164,139,342...164,188,418
Ensembl chr  X:164,139,332...164,188,420
JBrowse link
G Acly ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr11:100,476,352...100,528,000
Ensembl chr11:100,476,353...100,528,000
JBrowse link
G Actn2 actinin alpha 2 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 NCBI chr13:12,269,426...12,340,732
Ensembl chr13:12,269,426...12,340,760
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 treatment ISO associated with pulmonary hypertension RGD PMID:22628376 RGD:13703064 NCBI chr12:21,323,509...21,373,632
Ensembl chr12:21,323,509...21,373,632
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with cardiovascular disease; protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:19367012 PMID:26670611, PMID:22032915, PMID:18192035 RGD:5686388, RGD:5686806 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Adm adrenomedullin ISO RGD PMID:12623952 RGD:704370 NCBI chr 7:110,627,657...110,629,820
Ensembl chr 7:110,627,661...110,629,820
JBrowse link
G Adra2c adrenergic receptor, alpha 2c ISO DNA:deletion: :322_325del(human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of
CTD
ClinVar
PMID:12374873 PMID:17496726, PMID:12374873 RGD:1300355 NCBI chr 5:35,278,566...35,281,763
Ensembl chr 5:35,278,319...35,281,763
JBrowse link
G Adrb1 adrenergic receptor, beta 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of
DNA:polymorphism: :p.R389G (human)
CTD
ClinVar
PMID:7586371 PMID:10212248 PMID:12374873 PMID:14502278 PMID:15816327 PMID:16844790 PMID:17496726 PMID:21516734, PMID:19587314, PMID:14502278 RGD:5129119, RGD:737774 NCBI chr19:56,722,117...56,725,150
Ensembl chr19:56,722,199...56,733,113
JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
protein:altered localization:cardiac muscle cell
ClinVar PMID:8383511 PMID:15284533 PMID:16596417, PMID:19587314, PMID:20185685 RGD:5129119, RGD:4144900 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
G Adrb3 adrenergic receptor, beta 3 ISO protein:increased expression:left ventricle, myocardium (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart ventricle (rat)
CTD PMID:15009959 PMID:17440824, PMID:11273992, PMID:21549119 RGD:5684398, RGD:5684917 NCBI chr 8:27,225,776...27,230,845
Ensembl chr 8:27,225,776...27,250,616
JBrowse link
G Ager advanced glycosylation end product-specific receptor severity ISO protein:increased expression:plasma (human) RGD PMID:20685687 RGD:7244134 NCBI chr17:34,597,460...34,600,937
Ensembl chr17:34,597,862...34,600,936
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) onset
severity
treatment
ISO DNA:polymorphisms: :p.M235T, p.T174M (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD PMID:1330361 PMID:12025466 PMID:20811386, PMID:17145981, PMID:24465706, PMID:21963897 RGD:1601140, RGD:11039412, RGD:8549482 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr1a angiotensin II receptor, type 1a treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:17208988 PMID:18214293 PMID:18586661, PMID:21963897 RGD:8549482 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA, protein:decreased expression:heart RGD PMID:18768398, PMID:21963897 RGD:6903846, RGD:8549482 NCBI chr  X:21,484,624...21,488,833
Ensembl chr  X:21,484,544...21,489,164
JBrowse link
G Akap6 A kinase (PRKA) anchor protein 6 IMP RGD PMID:24812305 RGD:11251930 NCBI chr12:52,698,588...53,155,568
Ensembl chr12:52,699,383...53,155,599
JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr 5:3,927,736...4,080,204
Ensembl chr 5:3,928,054...4,081,310
JBrowse link
G Alb albumin disease_progression ISO CTD Direct Evidence: marker/mechanism CTD PMID:11771600, PMID:22158777 RGD:11036096 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr19:20,692,953...20,727,556
Ensembl chr19:20,692,953...20,727,562
JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO RGD PMID:15623566 RGD:5509787 NCBI chr11:70,241,457...70,255,380
Ensembl chr11:70,241,457...70,255,353
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO
IDA
associated with Myocardial Infarction; mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176, PMID:19546247 RGD:1642301, RGD:5509627 NCBI chr11:70,344,147...70,390,538
Ensembl chr11:70,344,152...70,352,031
JBrowse link
G Ank2 ankyrin 2, brain ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 NCBI chr 3:126,921,607...127,500,347
Ensembl chr 3:126,921,612...127,499,350
JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO associated with Cardiomyopathy, Congestive RGD PMID:15238456 RGD:2314858 NCBI chr 1:36,530,193...36,536,556
Ensembl chr 1:36,530,193...36,539,429
Ensembl chr 1:36,530,193...36,539,429
JBrowse link
G Aoc3 amine oxidase, copper containing 3 severity ISO protein:increased expression:plasma RGD PMID:11052858 RGD:2313827 NCBI chr11:101,330,606...101,339,430
Ensembl chr11:101,330,605...101,341,938
JBrowse link
G Apcs serum amyloid P-component ISO CTD Direct Evidence: marker/mechanism CTD PMID:16129801 NCBI chr 1:172,893,961...172,895,054
Ensembl chr 1:172,893,961...172,895,041
JBrowse link
G Apln apelin ISO protein:increased expression:ventricle myocardium
protein:decreased expression:plasma
associated with Hypertension, Pulmonary
RGD PMID:17119870, PMID:16263185, PMID:17055480 RGD:1626186, RGD:1626175, RGD:1626171 NCBI chr  X:48,025,146...48,034,853
Ensembl chr  X:48,025,146...48,034,853
JBrowse link
G Apoa1 apolipoprotein A-I ISO protein: decreased expression: serum RGD PMID:17517342 RGD:5508219 NCBI chr 9:46,228,630...46,230,469
Ensembl chr 9:46,228,580...46,230,466
JBrowse link
G Apoc1 apolipoprotein C-I ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 7:19,689,480...19,692,659
Ensembl chr 7:19,689,481...19,692,660
JBrowse link
G Apoe apolipoprotein E ISO associated with Beta-Thalassemia RGD PMID:9787187 RGD:11039487 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Arrb1 arrestin, beta 1 treatment ISO RGD PMID:21232674 RGD:5509888 NCBI chr 7:99,535,147...99,606,772
Ensembl chr 7:99,535,466...99,606,771
JBrowse link
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18418421 NCBI chr 7:24,978,167...25,006,077
Ensembl chr 7:24,978,167...25,005,958
JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19776660 NCBI chr 7:126,445,858...126,463,103
Ensembl chr 7:126,445,858...126,463,108
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19776660, PMID:21691940 RGD:6903963 NCBI chr 5:122,453,513...122,502,225
Ensembl chr 5:122,453,513...122,502,225
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18179782 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554
JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12145768 NCBI chr  X:73,891,765...73,894,428
Ensembl chr  X:73,892,102...73,895,502
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:18097624, PMID:29746994 RGD:10054097, RGD:13792577 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:18097624, PMID:29746994 RGD:10054097, RGD:13792577 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Becn1 beclin 1, autophagy related treatment ISO RGD PMID:18619688 RGD:11560532 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO associated with Hypertension;protein:decreased expression:cardiac muscle cell RGD PMID:16257070 RGD:2293134 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 treatment ISO RGD PMID:23508759 RGD:11561982 NCBI chr 7:138,890,836...138,909,506
Ensembl chr 7:138,890,836...138,909,519
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:118,587,240...119,197,384
Ensembl chr 6:118,587,240...119,196,890
Ensembl chr 6:118,587,240...119,196,890
JBrowse link
G Calr calreticulin IEA MouseDO NCBI chr 8:84,842,088...84,846,931
Ensembl chr 8:84,841,850...84,846,934
JBrowse link
G Casp1 caspase 1 IEP mRNA, protein:increased expression:heart left ventricle RGD PMID:17303764 RGD:2315913 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp12 caspase 12 treatment ISO associated with Hypertension
associated with myocardial infarction
RGD PMID:18787714, PMID:27346262 RGD:2311453, RGD:13782169 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:29746994 RGD:13792577 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casq2 calsequestrin 2 ISO mRNA:increased expression:sinoatrial node RGD PMID:21565973 RGD:6771208 NCBI chr 3:102,086,415...102,146,514
Ensembl chr 3:102,086,415...102,146,514
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16105639, PMID:10618301 RGD:1581151 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cbl Casitas B-lineage lymphoma ISO protein:increased expression:left ventricle myocardium, muscle cell (human) RGD PMID:24583314 RGD:11251947 NCBI chr 9:44,142,976...44,234,259
Ensembl chr 9:44,142,976...44,234,049
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO mRNA:increased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism
CTD PMID:29959987, PMID:12950323 RGD:1581156 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17229371 NCBI chr10:24,595,442...24,598,683
Ensembl chr10:24,595,442...24,598,683
JBrowse link
G Ccna2 cyclin A2 IMP RGD PMID:16820573 RGD:2293348 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnt1 cyclin T1 IMP RGD PMID:15297879 RGD:1556509 NCBI chr15:98,538,690...98,567,736
Ensembl chr15:98,538,689...98,570,923
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 ISO RGD PMID:12719858 RGD:1581177 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:15716285 RGD:2314219 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Cdk9 cyclin-dependent kinase 9 (CDC2-related kinase) ISO
IEP
protein:increased activity:ventricle:
protein:increased activity:heart:
RGD PMID:15297879, PMID:15297879 RGD:1556509, RGD:1556509 NCBI chr 2:32,705,782...32,712,784
Ensembl chr 2:32,705,784...32,713,076
JBrowse link
G Cfd complement factor D (adipsin) ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr10:79,890,853...79,892,655
Ensembl chr10:79,890,853...79,892,655
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO mRNA,protein:increased expression:cardiomyocyte: RGD PMID:11033112 RGD:11341730 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Chek2 checkpoint kinase 2 ISO protein:increased phosphorylation:heart myocardium RGD PMID:12702777 RGD:2289708 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Chil1 chitinase-like 1 ISO protein:increased secretion:plasma (human) RGD PMID:19961288 RGD:4892629 NCBI chr 1:134,182,156...134,190,031
Ensembl chr 1:134,182,176...134,190,181
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr 2:91,922,189...91,929,835
Ensembl chr 2:91,927,249...91,928,688
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr 2:181,022,311...181,043,579
Ensembl chr 2:181,018,380...181,043,546
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr18:67,343,564...67,367,794
Ensembl chr18:67,343,604...67,367,785
JBrowse link
G Corin corin, serine peptidase ISO mRNA:increased expression:heart (rat)
mRNA:decreased expression:left atrium, right atrium (rat)
RGD PMID:15191894, PMID:15155264 RGD:1581217, RGD:1581218 NCBI chr 5:72,299,948...72,504,540
Ensembl chr 5:72,300,025...72,504,473
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Cryab crystallin, alpha B ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:1560021 PMID:16483541 PMID:16793013 PMID:17116488 PMID:20171888 PMID:21920752 PMID:22106715 PMID:22995991 PMID:23194663 PMID:23299917 PMID:24033266 PMID:25208129 PMID:25741868 PMID:26694549 PMID:26961874 PMID:28492532 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636
JBrowse link
G Cs citrate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8922916 NCBI chr10:128,337,727...128,362,482
Ensembl chr10:128,337,734...128,362,479
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) ISO CTD Direct Evidence: marker/mechanism CTD PMID:11732872 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585077 NCBI chr11:98,700,183...98,703,631
Ensembl chr11:98,701,263...98,703,629
JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 IEA MouseDO NCBI chr 7:48,830,398...48,848,051
Ensembl chr 7:48,830,398...48,848,033
JBrowse link
G Cst3 cystatin C susceptibility ISO protein:increased expression:serum (human) RGD PMID:19539088 RGD:2314311 NCBI chr 2:148,871,722...148,875,512
Ensembl chr 2:148,871,722...148,875,692
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 ISO mRNA, protein:increased expression: paraventricular nucleus of hypothalamus RGD PMID:24036597 RGD:9491792 NCBI chr 9:120,048,683...120,068,296
Ensembl chr 9:119,901,616...120,069,879
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Cybb cytochrome b-245, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr  X:9,435,252...9,487,766
Ensembl chr  X:9,435,252...9,487,771
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 ISO protein:increased expression:heart (rat) RGD PMID:19571523 RGD:4891162 NCBI chr15:74,850,618...74,856,231
Ensembl chr15:74,851,010...74,856,318
JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr17:32,536,545...32,551,798
Ensembl chr17:32,536,558...32,551,798
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr17:35,681,567...35,704,741
Ensembl chr17:35,681,567...35,704,621
JBrowse link
G Dio3 deiodinase, iodothyronine type III ISO associated with Hypertrophy, Right Ventricular;mRNA, protein:increased expression:heart right ventricle RGD PMID:18259611 RGD:2303417 NCBI chr12:110,279,230...110,281,097
Ensembl chr12:110,279,068...110,281,097
JBrowse link
G Dmd dystrophin, muscular dystrophy ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 ISO protein:increased expression:atrium: RGD PMID:23573917 RGD:9588286 NCBI chr 9:20,907,206...20,959,888
Ensembl chr 9:20,907,209...20,959,888
JBrowse link
G Dstn destrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 2:143,915,331...143,943,324
Ensembl chr 2:143,915,320...143,943,324
JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO protein:increased expression:paraventricular nucleus RGD PMID:23832698 RGD:7257598 NCBI chr 5:115,297,110...115,300,990
Ensembl chr 5:115,297,110...115,300,999
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO mRNA,protein:increased expression:kidney:
associated with myocardial ischemia
RGD PMID:11145756, PMID:9595392, PMID:19596829 RGD:1580911, RGD:7244244, RGD:7243876 NCBI chr 4:137,862,237...137,965,229
Ensembl chr 4:137,862,237...137,965,229
JBrowse link
G Edn1 endothelin 1 severity
treatment
ISO protein:increased secretion:plasma (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart:
CTD PMID:7967349 PMID:7969316 PMID:9861300 PMID:11136700 PMID:11707688 PMID:16360360 PMID:16762801, PMID:8149524, PMID:10973842, PMID:10199843 RGD:4144845, RGD:8661798, RGD:7244167 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Ednra endothelin receptor type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464
JBrowse link
G Ednrb endothelin receptor type B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chr14:103,814,615...103,844,508
Ensembl chr14:103,814,625...103,844,402
JBrowse link
G Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 3:129,532,386...129,638,495
Ensembl chr 3:129,532,355...129,638,495
JBrowse link
G Endog endonuclease G ISO mRNa:decreased expression:heart: RGD PMID:17292393 RGD:9685393 NCBI chr 2:30,171,408...30,174,069
Ensembl chr 2:30,171,493...30,174,069
JBrowse link
G Eng endoglin treatment ISO protein:increased expression:heart left ventricle (rat) RGD PMID:20156938, PMID:20156938 RGD:7257540, RGD:7257540 NCBI chr 2:32,646,595...32,682,669
Ensembl chr 2:32,646,595...32,682,669
JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chr15:81,586,209...81,652,077
Ensembl chr15:81,585,351...81,652,077
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic ISO CTD Direct Evidence: marker/mechanism CTD PMID:18443590 NCBI chr14:66,084,372...66,124,522
Ensembl chr14:66,084,374...66,124,500
JBrowse link
G Epo erythropoietin treatment ISO associated with Myocardial Infarction RGD PMID:20139114 RGD:10401073 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:10421602 RGD:1580989 NCBI chr11:98,412,484...98,437,716
Ensembl chr11:98,412,470...98,437,716
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO associated with Aortic Valve Stenosis;mRNA, protein:decreased expression:heart myocardium RGD PMID:10421602 RGD:1580989 NCBI chr 1:68,031,884...69,108,576
Ensembl chr 1:68,032,186...69,108,059
JBrowse link
G Esrra estrogen related receptor, alpha ISO protein:decreased expression:heart: RGD PMID:21825219 RGD:10401867 NCBI chr19:6,910,977...6,922,048
Ensembl chr19:6,910,977...6,921,813
Ensembl chr19:6,910,977...6,921,813
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 ISO DNA:deletion:introns, exon (human)
ClinVar Annotator: match by term: Congestive heart failure
ClinVar PMID:25741868 PMID:28492532, PMID:15735644 RGD:1598455 NCBI chr10:23,102,962...23,350,838
Ensembl chr10:23,102,963...23,350,786
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO mRNA:splice variant:heart left ventricle (human) RGD PMID:9367848, PMID:29746994 RGD:8686420, RGD:13792577 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) treatment ISO RGD PMID:29746994 RGD:13792577 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fbln5 fibulin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189163 NCBI chr12:101,746,565...101,819,119
Ensembl chr12:101,746,565...101,819,055
JBrowse link
G Fip1l1 FIP1 like 1 (S. cerevisiae) ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chr 5:74,535,438...74,598,790
Ensembl chr 5:74,535,449...74,598,800
JBrowse link
G Fkbp1b FK506 binding protein 1b ISO associated with Shock, Septic RGD PMID:17637193 RGD:2302075 NCBI chr12:4,833,176...4,841,573
Ensembl chr12:4,833,174...4,841,591
JBrowse link
G Fos FBJ osteosarcoma oncogene ISO RGD PMID:15623567 RGD:2293777 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosl1 fos-like antigen 1 ISO RGD PMID:15623567 RGD:2293777 NCBI chr19:5,447,698...5,455,938
Ensembl chr19:5,447,547...5,455,946
JBrowse link
G Foxc1 forkhead box C1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr13:31,806,646...31,810,635
Ensembl chr13:31,806,633...31,812,476
JBrowse link
G Foxc2 forkhead box C2 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 8:121,116,171...121,118,895
Ensembl chr 8:121,116,171...121,118,895
JBrowse link
G Foxo1 forkhead box O1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 3:52,268,337...52,350,109
Ensembl chr 3:52,268,336...52,353,221
JBrowse link
G Foxp1 forkhead box P1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 6:98,925,342...99,522,746
Ensembl chr 6:98,925,338...99,522,721
JBrowse link
G Foxp4 forkhead box P4 ISO RGD PMID:16952980 RGD:1582564 NCBI chr17:47,867,133...47,924,632
Ensembl chr17:47,867,133...47,924,645
JBrowse link
G Fth1 ferritin heavy polypeptide 1 ISO protein:decreased expression:heart RGD PMID:18992754 RGD:2315110 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 ISO protein:increased serine phosphorylation:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chr 7:31,051,678...31,055,873
Ensembl chr 7:31,051,678...31,057,199
JBrowse link
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16820567 NCBI chr 2:122,594,473...122,611,277
Ensembl chr 2:122,594,467...122,611,303
JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:7608802 NCBI chr 2:62,474,530...62,483,653
Ensembl chr 2:62,474,530...62,483,650
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr 8:70,629,393...70,632,470
Ensembl chr 8:70,629,393...70,632,456
JBrowse link
G Ghrl ghrelin ISO CTD Direct Evidence: therapeutic CTD PMID:20572026 NCBI chr 6:113,716,119...113,719,911
Ensembl chr 6:113,716,119...113,719,880
JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide IEA MouseDO NCBI chr19:16,132,684...16,388,520
Ensembl chr19:16,132,831...16,387,463
JBrowse link
G Gpx4 glutathione peroxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr10:80,047,166...80,056,439
Ensembl chr10:80,047,166...80,056,439
JBrowse link
G Grk1 G protein-coupled receptor kinase 1 ISO RGD PMID:12456492 RGD:1600002 NCBI chr 8:13,405,081...13,421,951
Ensembl chr 8:13,405,081...13,421,951
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IAGP
ISO
mRNA:decreased expression:peripheral blood mononuclear cell (human)
CTD Direct Evidence: marker/mechanism
associated with Hypertrophy, Left Ventricular and Hypertension;protein:increased expression, increased activity:heart left ventricle, cytosol (rat)
CTD PMID:26670611, PMID:11331748, PMID:26248277, PMID:29247373, PMID:9931137 RGD:737776, RGD:11535540, RGD:13506830, RGD:1625790 NCBI chr19:4,285,999...4,306,222
Ensembl chr19:4,286,001...4,306,222
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 severity ISO mRNA:decreased expression:heart left ventricle (human) RGD PMID:22685168 RGD:13506835 NCBI chr 5:112,910,478...113,015,660
Ensembl chr 5:112,910,482...113,015,791
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 severity ISO mRNA:decreased expression:heart left ventricle (human)
mRNA:decreased expression:peripheral blood mononuclear cell (human)
RGD PMID:22685168, PMID:26248277 RGD:13506835, RGD:11535540 NCBI chr19:60,889,560...61,095,968
Ensembl chr19:60,889,749...61,095,968
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901358 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:serum, urine RGD PMID:21080339 RGD:11041621 NCBI chr 7:30,942,368...30,944,029
Ensembl chr 7:30,942,368...30,944,032
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 8:57,320,983...57,324,517
Ensembl chr 8:57,320,983...57,324,633
JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:58,822,949...58,863,175
Ensembl chr 9:58,823,412...58,863,175
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO protein:increased expression:heart right ventricle (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:15732037, PMID:17582388 RGD:9068910 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO protein:decreased expression:heart RGD PMID:23708738, PMID:24204700 RGD:10402070, RGD:10402081 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330, PMID:23592614 RGD:10755584 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hp haptoglobin treatment ISO RGD PMID:23494325 RGD:11041812 NCBI chr 8:109,575,128...109,579,172
Ensembl chr 8:109,575,128...109,579,172
JBrowse link
G Hrh2 histamine receptor H2 susceptibility IMP RGD PMID:24655024 RGD:9685523 NCBI chr13:54,191,970...54,236,182
Ensembl chr13:54,192,129...54,236,180
JBrowse link
G Hsf1 heat shock factor 1 ISO protein:altered localization:heart left ventricle (rat) RGD PMID:24285117 RGD:10402754 NCBI chr15:76,477,362...76,501,155
Ensembl chr15:76,477,422...76,501,913
JBrowse link
G Hspb1 heat shock protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17481944 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO mRNA:increased expression:heart left ventricle RGD PMID:16002744 RGD:1600503 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B ISO mRNA:increased expression:left ventricle cardiac muscle (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:19023134, PMID:17936780 RGD:9698457 NCBI chr 1:86,097,546...86,116,231
Ensembl chr 1:86,099,026...86,111,970
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:3091246 PMID:20938210 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:12835956 RGD:1598415 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Il10 interleukin 10 disease_progression
treatment
IEP
ISO
RGD PMID:16461369, PMID:28939262, PMID:23778495 RGD:1598465, RGD:14975271, RGD:7365020 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il17a interleukin 17A ISO protein:increased expression:heart RGD PMID:19909738, PMID:19527710 RGD:2325816, RGD:4831836 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15135663 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 ISO associated with Hypertension;mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental; protein:increased expression:extracellular space (rat)
CTD PMID:15135663 PMID:16360360, PMID:18280594, PMID:28939262, PMID:18999900 RGD:5128682, RGD:14975271, RGD:2307285 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Il6ra interleukin 6 receptor, alpha ISO protein:increased expression:paraventricular hypothalamic nucleus RGD PMID:17095650 RGD:1625433 NCBI chr 3:89,869,324...89,913,196
Ensembl chr 3:89,864,059...89,913,196
JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:15628829 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884376 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200
JBrowse link
G Kat8 K(lysine) acetyltransferase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27768893 NCBI chr 7:127,912,517...127,925,838
Ensembl chr 7:127,912,516...127,925,837
JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 ISO associated with Myocardial Infarction (RDO:0006167); mRNA:increased expression:heart left ventricle, septum (rat)
mRNA:increased expression:endocardium of right ventricle:
RGD PMID:16497176, PMID:17384445 RGD:1642301, RGD:12910696 NCBI chr16:92,346,001...92,359,468
Ensembl chr16:92,345,982...92,359,468
JBrowse link
G Kcnk2 potassium channel, subfamily K, member 2 ISO associated with Hypertension, Pulmonary:mRNA:decreased expression:heart right ventricle (rat) RGD PMID:25016242 RGD:9831185 NCBI chr 1:189,207,930...189,402,782
Ensembl chr 1:189,207,930...189,402,273
JBrowse link
G Kdm2a lysine (K)-specific demethylase 2A IEP protein:altered localization:promoter (mouse) RGD PMID:25181347 RGD:9588275 NCBI chr19:4,316,144...4,398,721
Ensembl chr19:4,314,419...4,398,285
JBrowse link
G Lep leptin IMP RGD PMID:18006469 RGD:5128823 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lepr leptin receptor IEP protein:increased phosphorylation:heart RGD PMID:18006469 RGD:5128823 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO RGD PMID:15520318 RGD:9685214 NCBI chr14:47,373,860...47,386,167
Ensembl chr14:47,367,751...47,386,160
JBrowse link
G Lif leukemia inhibitory factor ISO RGD PMID:20051627 RGD:2326058 NCBI chr11:4,257,568...4,272,514
Ensembl chr11:4,257,557...4,272,514
JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chr 8:4,238,740...4,247,897
Ensembl chr 8:4,238,740...4,247,897
Ensembl chr 8:4,238,740...4,247,897
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP protein:increased activity:heart: RGD PMID:17562954 RGD:10412331 NCBI chr10:19,934,101...20,142,750
Ensembl chr10:19,934,472...20,142,753
JBrowse link
G Mas1 MAS1 oncogene ISO mRNA, protein:decreased expression:heart RGD PMID:21963897 RGD:8549482 NCBI chr17:12,838,841...12,868,150
Ensembl chr17:12,841,079...12,868,143
JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) ISO RGD PMID:16786185 RGD:1582470 NCBI chr 5:135,778,649...135,790,386
Ensembl chr 5:135,778,480...135,790,398
JBrowse link
G Med1 mediator complex subunit 1 IEA MouseDO NCBI chr11:98,152,154...98,193,313
Ensembl chr11:98,152,154...98,193,293
JBrowse link
G Mir133a-2 microRNA 133a-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 2:180,398,379...180,398,482
Ensembl chr 2:180,398,379...180,398,482
JBrowse link
G Mir27a microRNA 27a ISO RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr 8:84,208,672...84,208,758
Ensembl chr 8:84,208,672...84,208,758
JBrowse link
G Mir28a microRNA 28a ISO RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr16:24,827,855...24,827,940
Ensembl chr16:24,827,855...24,827,940
JBrowse link
G Mir34a microRNA 34a ISO RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr 4:150,068,454...150,068,555
Ensembl chr 4:150,068,454...150,068,555
JBrowse link
G Mme membrane metallo endopeptidase ISO RGD PMID:12383878 RGD:13801043 NCBI chr 3:63,295,211...63,383,713
Ensembl chr 3:63,241,537...63,386,030
JBrowse link
G Mmp13 matrix metallopeptidase 13 disease_progression ISO protein:increased expression:left ventricle (rat)
associated with Hypertension
RGD PMID:10773235, PMID:10773234 RGD:1582587, RGD:2290467 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) disease_progression ISO protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chr14:54,431,598...54,442,456
Ensembl chr14:54,431,612...54,445,364
JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) ISO RGD PMID:12892382, PMID:21866669 RGD:1582539, RGD:7207282 NCBI chr 9:7,464,141...7,476,869
Ensembl chr 9:7,464,141...7,476,869
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO RGD PMID:12892382 RGD:1582539 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO mRNA:increased expression:heart left ventricle
protein:increased expression:heart left ventricle, plasma
RGD PMID:10773234, PMID:20606426, PMID:16169329 RGD:2290467, RGD:8694112, RGD:1582574 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein:increased expression:heart left ventricle, plasma RGD PMID:20606426 RGD:8694112 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp8 matrix metallopeptidase 8 disease_progression ISO protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chr 9:7,558,429...7,568,486
Ensembl chr 9:7,558,456...7,568,485
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO associated with Hypertension, Pulmonary; protein:increased expression:heart
protein:increased expression:heart left ventricle, plasma
RGD PMID:17913382, PMID:20606426, PMID:11342481, PMID:16952784 RGD:5130174, RGD:8694112, RGD:7207137, RGD:1582647 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mstn myostatin ISO mRNA, protein:increased expression:myocardium
CTD Direct Evidence: marker/mechanism
CTD PMID:16968467, PMID:16968467 RGD:2303554 NCBI chr 1:53,061,640...53,068,079
Ensembl chr 1:53,061,640...53,068,079
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO mRNA, protein:increased expression:heart RGD PMID:20861467 RGD:10003169 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Mtpn myotrophin IEA MouseDO NCBI chr 6:35,508,824...35,539,888
Ensembl chr 6:35,508,906...35,539,888
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha treatment ISO mRNA:decreased expression:heart left ventricle
ClinVar Annotator: match by term: Heart failure
ClinVar Annotator: match by term: Congestive heart failure
associated with Myocardial Infarction
ClinVar PMID:20656787 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532, PMID:9410916, PMID:18088389 RGD:1580923, RGD:12792974 NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta treatment ISO associated with Myocardial Infarction RGD PMID:18088389 RGD:12792974 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626
JBrowse link
G Myod1 myogenic differentiation 1 treatment ISO associated with Aortic Valve Stenosis RGD PMID:20060348 RGD:9686081 NCBI chr 7:46,376,474...46,379,092
Ensembl chr 7:46,376,474...46,379,099
JBrowse link
G Myot myotilin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr18:44,334,053...44,355,740
Ensembl chr18:44,334,074...44,355,724
JBrowse link
G Mypn myopalladin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:22286171 PMID:23299917 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr10:63,115,795...63,203,952
Ensembl chr10:63,115,795...63,203,952
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO mRNA, protein:increased expression:heart RGD PMID:19853610 RGD:2325979 NCBI chr 9:49,502,129...49,799,393
Ensembl chr 9:49,502,136...49,798,925
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 ISO CTD Direct Evidence: therapeutic CTD PMID:28373008, PMID:29373037 RGD:26923905 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) ISO associated with Myocardial Infarction;mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr11:95,568,818...95,587,698
Ensembl chr11:95,568,818...95,587,735
JBrowse link
G Nisch nischarin ISO RGD PMID:12021582 RGD:1581128 NCBI chr14:31,170,928...31,206,826
Ensembl chr14:31,170,930...31,216,946
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO protein:increased expression:heart, left ventricle, sarcolemma (human) RGD PMID:11121795 RGD:5132888 NCBI chr11:93,949,814...93,956,256
Ensembl chr11:93,949,814...93,956,259
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO RGD PMID:15466641, PMID:23832698 RGD:1581144, RGD:7257598 NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840
JBrowse link
G Nos1ap nitric oxide synthase 1 (neuronal) adaptor protein ISO mRNA:increased expression:brain RGD PMID:21831995 RGD:7327163 NCBI chr 1:170,315,467...170,589,849
Ensembl chr 1:170,302,668...170,589,861
JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD PMID:19168511 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:19168511 PMID:20304815, PMID:29351461 RGD:13504746 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Nox1 NADPH oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr  X:134,086,421...134,137,711
Ensembl chr  X:134,086,421...134,221,956
JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 7:87,244,430...87,398,710
Ensembl chr 7:87,246,096...87,398,710
JBrowse link
G Nppa natriuretic peptide type A treatment
severity
ISO mRNA,protein:increased expression:heart,plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
CTD PMID:1647690 PMID:8112904 PMID:11136700 PMID:16101196, PMID:11421854, PMID:23931972, PMID:23566312, PMID:2143809 RGD:1580139, RGD:7297049, RGD:7247714, RGD:1580140 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079
JBrowse link
G Nppb natriuretic peptide type B severity ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus;protein:increased expression:plasma
mRNA,protein:increased expression:heart,plasma
CTD PMID:11136700 PMID:11279304 PMID:12628948 PMID:15732037 PMID:15860969 PMID:16101196 PMID:16333235 PMID:16360360 PMID:16762801 PMID:16777915 PMID:19650993 PMID:24535859 PMID:29959987, PMID:2143809, PMID:1831369, PMID:17257273, PMID:11421854 RGD:1580140, RGD:7247316, RGD:1642196, RGD:1580139 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205
JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP
ISO
IEP
associated with Hypertension
CTD Direct Evidence: marker/mechanism
protein:decreased expression:kidney
CTD PMID:20881240, PMID:9405681, PMID:17264312 RGD:737701, RGD:7247730 NCBI chr 3:90,450,591...90,465,928
Ensembl chr 3:90,450,591...90,465,866
JBrowse link
G Nptxr neuronal pentraxin receptor ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr15:79,786,351...79,804,709
Ensembl chr15:79,786,351...79,804,766
JBrowse link
G Npy neuropeptide Y ISO RGD PMID:17804485 RGD:7175103 NCBI chr 6:49,822,710...49,829,507
Ensembl chr 6:49,822,710...49,829,507
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment ISO RGD PMID:21737535 RGD:7174712 NCBI chr18:39,410,545...39,519,421
Ensembl chr18:39,410,545...39,519,421
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15722665 PMID:21321305 NCBI chr 8:76,898,083...77,245,012
Ensembl chr 8:76,899,442...77,245,012
JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19801490 NCBI chr 8:31,807,452...32,891,609
Ensembl chr 8:31,814,551...32,884,797
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr16:76,287,403...76,373,827
Ensembl chr16:76,287,400...76,373,827
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) ISO protein:increased expression:heart left ventricle (rat) RGD PMID:22128088 RGD:9590202 NCBI chr  X:101,640,011...101,684,351
Ensembl chr  X:101,640,060...101,684,351
JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 6:129,479,150...129,507,350
Ensembl chr 6:129,485,244...129,507,165
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase ISO protein:decreased expression:heart RGD PMID:19493956 RGD:7800717 NCBI chr16:29,579,281...29,663,127
Ensembl chr16:29,579,334...29,654,884
JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 ISO associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr 5:122,707,518...122,729,739
Ensembl chr 5:122,707,544...122,729,738
JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 2:102,549,939...102,643,041
Ensembl chr 2:102,550,012...102,643,041
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 treatment ISO associated with Hypertension RGD PMID:19443425 RGD:11074236 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 2:173,153,073...173,159,274
Ensembl chr 2:173,153,048...173,159,273
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IEP protein:decreased expression:heart: RGD PMID:23647599 RGD:10448278 NCBI chr10:7,627,845...7,681,337
Ensembl chr10:7,629,373...7,681,136
JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chr 5:75,151,322...75,198,206
Ensembl chr 5:75,152,292...75,198,215
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19429709 NCBI chr17:24,073,680...24,155,619
Ensembl chr17:24,073,680...24,150,924
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 5:117,282,651...117,287,564
Ensembl chr 5:117,282,654...117,287,625
JBrowse link
G Pgf placental growth factor ISO RGD PMID:19327525 RGD:6483590 NCBI chr12:85,166,637...85,177,785
Ensembl chr12:85,166,635...85,177,790
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:12963636, PMID:15936620 RGD:6482699 NCBI chr12:32,173,397...32,208,677
Ensembl chr12:32,173,473...32,208,659
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ISO RGD PMID:16952920 RGD:6482778 NCBI chr17:43,567,994...43,612,202
Ensembl chr17:43,568,098...43,612,201
JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 8:22,757,722...22,782,848
Ensembl chr 8:22,757,727...22,782,844
JBrowse link
G Plcd1 phospholipase C, delta 1 ISO RGD PMID:11181012 RGD:2300431 NCBI chr 9:119,071,527...119,093,502
Ensembl chr 9:119,071,527...119,093,502
JBrowse link
G Pld2 phospholipase D2 ISO protein:increased expression:heart left ventricle RGD PMID:15601581 RGD:2299908 NCBI chr11:70,539,492...70,558,110
Ensembl chr11:70,540,064...70,558,110
JBrowse link
G Pln phospholamban treatment ISO associated with Hypertension
associated with Myocardial Infarction
RGD PMID:22970977, PMID:22947202 RGD:7327181, RGD:7327182 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987
JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:3026683 PMID:8277081 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Postn periostin, osteoblast specific factor treatment ISO mRNA:increased expression:heart RGD PMID:16414453, PMID:15381649 RGD:10040951, RGD:10040999 NCBI chr 3:54,359,267...54,391,041
Ensembl chr 3:54,361,109...54,391,037
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha onset IDA
IEA
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:heart (mouse)
MouseDO
CTD
PMID:19808358 PMID:22503866, PMID:23342071, PMID:23297372 RGD:7241838, RGD:7241843 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha IMP RGD PMID:12024026 RGD:737728 NCBI chr19:4,192,174...4,195,419
Ensembl chr19:4,192,065...4,195,420
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO protein:increased expression:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chr 5:122,154,967...122,175,273
Ensembl chr 5:122,158,278...122,175,273
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A ISO CTD Direct Evidence: therapeutic CTD PMID:20071777 NCBI chr15:103,530,279...103,538,027
Ensembl chr15:103,530,279...103,538,003
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform ISO mRNA:increased expression:vastus lateralis muscle (human) RGD PMID:14567976 RGD:8693707 NCBI chr11:52,098,824...52,122,749
Ensembl chr11:52,098,681...52,127,778
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chr 8:83,972,978...83,996,444
Ensembl chr 8:83,972,993...83,996,443
JBrowse link
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit ISO ClinVar Annotator: match by term: Congestive heart failure
ClinVar Annotator: match by term: Heart failure
ClinVar PMID:21409595 PMID:24033266 PMID:25741868 PMID:27532257 PMID:28492532 NCBI chr 5:24,862,735...25,106,282
Ensembl chr 5:24,862,744...25,100,642
JBrowse link
G Prkar2a protein kinase, cAMP dependent regulatory, type II alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chr 9:108,692,143...108,750,444
Ensembl chr 9:108,689,314...108,750,436
JBrowse link
G Prkar2b protein kinase, cAMP dependent regulatory, type II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr12:31,958,450...32,061,648
Ensembl chr12:31,958,476...32,061,296
JBrowse link
G Prkca protein kinase C, alpha ISO protein:increased expression, increased phosphorylation:heart left ventricle RGD PMID:17556659 RGD:2292480 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928
JBrowse link
G Prkcb protein kinase C, beta ISO associated with hypertension RGD PMID:12392998 RGD:1625516 NCBI chr 7:122,289,104...122,634,402
Ensembl chr 7:122,288,751...122,634,402
JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18926768 NCBI chr13:27,057,570...27,065,204
Ensembl chr13:27,057,570...27,065,205
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:17162251, PMID:21939825 RGD:7242422 NCBI chr 7:113,385,576...113,388,672
Ensembl chr 7:113,385,580...113,388,570
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 4:118,208,213...118,291,405
Ensembl chr 4:118,208,213...118,291,405
JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16155095, PMID:12642504 RGD:1581295 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Ramp2 receptor (calcitonin) activity modifying protein 2 ISO associated with Hypertension RGD PMID:12623952 RGD:704370 NCBI chr11:101,246,334...101,248,250
Ensembl chr11:101,246,028...101,259,546
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 ISO mRNA, protein:increased expression:left ventricle myocardium (human) RGD PMID:18323524 RGD:9835356 NCBI chr15:97,744,770...97,768,419
Ensembl chr15:97,744,770...97,767,972
JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868 PMID:28492532 NCBI chr19:53,660,989...53,867,083
Ensembl chr19:53,677,306...53,867,080
JBrowse link
G Rbp4 retinol binding protein 4, plasma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr19:38,116,620...38,125,321
Ensembl chr19:38,116,629...38,125,281
JBrowse link
G Ren1 renin 1 structural ISO CTD Direct Evidence: marker/mechanism CTD PMID:1647690 PMID:7034517 PMID:20811386 NCBI chr 1:133,350,674...133,360,320
Ensembl chr 1:133,350,510...133,360,325
JBrowse link
G Retn resistin ISO associated with Coronary Disease
CTD Direct Evidence: marker/mechanism
CTD PMID:26670611, PMID:22240747 RGD:7207075 NCBI chr 8:3,655,770...3,659,818
Ensembl chr 8:3,655,770...3,660,110
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO RGD PMID:21297953 RGD:7327162 NCBI chr19:33,137,740...33,392,295
Ensembl chr19:33,137,747...33,392,295
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr12:16,894,978...16,988,274
Ensembl chr12:16,894,895...16,987,823
JBrowse link
G Rrad Ras-related associated with diabetes ISO mRNA, protein:decreased expression:heart RGD PMID:18056528 RGD:2311701 NCBI chr 8:104,628,070...104,631,350
Ensembl chr 8:104,628,070...104,631,327
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868, PMID:16483256 RGD:1599251 NCBI chr13:11,553,099...12,106,945
Ensembl chr13:11,553,102...12,106,945
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO mRNA:decreased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chr 9:119,483,404...119,579,030
Ensembl chr 9:119,483,408...119,579,016
JBrowse link
G Scn8a sodium channel, voltage-gated, type VIII, alpha ISO mRNA:increased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chr15:100,869,863...101,045,938
Ensembl chr15:100,869,858...101,045,938
JBrowse link
G Selp selectin, platelet ISO RGD PMID:19193626 RGD:2312309 NCBI chr 1:164,115,264...164,150,026
Ensembl chr 1:164,115,264...164,150,026
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24535859 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Sirt3 sirtuin 3 ISO protein:decreased expression:heart left ventricle RGD PMID:22155497 RGD:9586040 NCBI chr 7:140,863,663...140,882,309
Ensembl chr 7:140,863,666...140,882,309
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 severity ISO protein:decreased expression:skeletal muscle RGD PMID:18778861 RGD:2313624 NCBI chr11:69,942,286...69,948,216
Ensembl chr11:69,942,539...69,948,188
JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 ISO DNA:repeat:promoter (human) RGD PMID:17307423 RGD:4889438 NCBI chr11:76,998,597...77,032,343
Ensembl chr11:76,998,603...77,032,340
JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 ISO protein:increased expression:cardiac muscle cell RGD PMID:17536604 RGD:1642720 NCBI chr17:81,373,105...81,738,387
Ensembl chr17:81,373,105...81,738,377
JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027022, PMID:18776042 RGD:6771337 NCBI chr 4:133,369,711...133,423,702
Ensembl chr 4:133,369,706...133,423,702
JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO
IEA
CTD Direct Evidence: marker/mechanism CTD
MouseDO
PMID:16105639 PMID:16155095 PMID:20304815 PMID:21195081 PMID:21284947 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sod3 superoxide dismutase 3, extracellular ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418
JBrowse link
G Sox4 SRY (sex determining region Y)-box 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr13:28,948,919...28,953,699
Ensembl chr13:28,948,919...28,953,713
JBrowse link
G Srf serum response factor ISO mRNA, protein:splice variant:heart RGD PMID:11893590 RGD:1581426 NCBI chr17:46,546,838...46,558,267
Ensembl chr17:46,548,329...46,556,175
JBrowse link
G Sri sorcin ISO protein:decreased expression:cardiac muscle cell
associated with Hypertension
RGD PMID:20945956, PMID:12754254 RGD:7327198, RGD:7327200 NCBI chr 5:8,046,078...8,069,314
Ensembl chr 5:8,046,078...8,069,379
JBrowse link
G Tbx20 T-box 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 9:24,720,812...24,774,303
Ensembl chr 9:24,718,138...24,774,303
JBrowse link
G Th tyrosine hydroxylase ISO
IMP
protein:increased expression:paraventricular thalamic nucleus (rat) RGD PMID:21287352, PMID:7715703 RGD:5128674, RGD:737737 NCBI chr 7:142,892,779...142,899,995
Ensembl chr 7:142,892,752...142,931,128
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 ISO protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 ISO protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr11:118,301,061...118,355,411
Ensembl chr11:118,301,069...118,355,740
JBrowse link
G Timp4 tissue inhibitor of metalloproteinase 4 ISO protein:decreased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr 6:115,244,444...115,252,205
Ensembl chr 6:115,241,892...115,252,205
JBrowse link
G Tlr2 toll-like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 3:83,836,272...83,841,824
Ensembl chr 3:83,836,272...83,841,767
JBrowse link
G Tnf tumor necrosis factor treatment
severity
ISO
IEA
CTD Direct Evidence: marker/mechanism
associated with Myocardial Infarction;
CTD
MouseDO
PMID:15135663 PMID:15231041 PMID:17337591 PMID:18034274 PMID:29959987, PMID:15210453, PMID:28939262, PMID:11668085, PMID:11100001 RGD:1580213, RGD:14975271, RGD:7401242, RGD:7401241 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) ISO mRNA, protein:incereased expression:myocardium RGD PMID:15883214 RGD:1624176 NCBI chr15:54,250,619...54,278,484
Ensembl chr15:54,250,619...54,278,484
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO human protein in rat model RGD PMID:21135513 RGD:5131262 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link
G Tnnt2 troponin T2, cardiac ISO CTD Direct Evidence: marker/mechanism CTD PMID:12322705 PMID:17698733 NCBI chr 1:135,836,315...135,852,268
Ensembl chr 1:135,836,354...135,852,260
JBrowse link
G Tomm70a translocase of outer mitochondrial membrane 70A ISO mRNA:decreased expression:heart
protein:increased serine phosphorylation:heart, mitochondrion
RGD PMID:25022898, PMID:24395194 RGD:13464131, RGD:13464132 NCBI chr16:57,121,714...57,154,530
Ensembl chr16:57,121,703...57,156,705
JBrowse link
G Trp53 transformation related protein 53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Congestive heart failure
ClinVar Annotator: match by term: Heart failure
ClinVar Annotator: match by term: CHF
ClinVar PMID:15802564 PMID:23396983 PMID:23486992 PMID:23861362 PMID:24033266 PMID:24055113 PMID:24231549 PMID:24271327 PMID:24503780 PMID:24569025 PMID:24578547 PMID:25589632 PMID:25741868 PMID:26272908 PMID:26383259 PMID:26467025 PMID:26498160 PMID:26516846 PMID:27194543 PMID:27843123 PMID:28256728 PMID:28492532 PMID:29361395 NCBI chr 2:76,703,980...76,982,557
Ensembl chr 2:76,703,980...76,982,547
JBrowse link
G Ttr transthyretin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:1355416 PMID:1850190 PMID:1997217 PMID:2174830 PMID:2590199 PMID:6736244 PMID:7923855 PMID:8102146 PMID:9090525 PMID:14640030 PMID:15185492 PMID:19428025 PMID:22332999 PMID:24033266 PMID:24955979 PMID:25741868 PMID:28492532 NCBI chr18:20,664,209...20,674,326
Ensembl chr18:20,665,280...20,674,321
JBrowse link
G Tubb5 tubulin, beta 5 class I EXP CTD Direct Evidence: marker/mechanism CTD PMID:16155095 NCBI chr17:35,833,920...35,838,301
Ensembl chr17:35,833,921...35,838,306
JBrowse link
G Ucn urocortin ISO protein:increased secretion:plasma (human) RGD PMID:19808377 RGD:5490589 NCBI chr 5:31,137,989...31,138,895
Ensembl chr 5:31,138,063...31,138,829
JBrowse link
G Ucn2 urocortin 2 ISO mRNA, protein:increased expression:myocardium (human)
CTD Direct Evidence: therapeutic
CTD PMID:16330704, PMID:12076554 RGD:5508210 NCBI chr 9:108,986,163...108,987,164
Ensembl chr 9:108,986,010...108,987,164
JBrowse link
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 8:83,290,348...83,298,456
Ensembl chr 8:83,290,352...83,298,452
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) ISO protein:decreased expression:heart, mitochondria RGD PMID:20809120, PMID:20193183 RGD:7204424, RGD:7204426 NCBI chr 7:100,493,337...100,499,629
Ensembl chr 7:100,493,337...100,502,020
JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) ISO protein:decreased expression:heart, mitochondria RGD PMID:20809120 RGD:7204424 NCBI chr 7:100,472,991...100,486,432
Ensembl chr 7:100,472,990...100,486,432
JBrowse link
G Uts2 urotensin 2 severity ISO protein:increased expression:plasma RGD PMID:16364499, PMID:12791592 RGD:2306804, RGD:1580809 NCBI chr 4:150,997,097...151,001,810
Ensembl chr 4:150,997,097...151,001,810
JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:24033266 PMID:28492532 NCBI chr14:20,929,383...21,033,676
Ensembl chr14:20,929,398...21,033,676
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15732037 PMID:15880336 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vwf Von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 6:125,552,948...125,686,679
Ensembl chr 6:125,546,774...125,686,679
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16436767 NCBI chr 2:164,579,519...164,585,784
Ensembl chr 2:164,579,519...164,585,447
JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19933411 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
G Yy1 YY1 transcription factor ISO RGD PMID:12754214 RGD:1580831 NCBI chr12:108,792,945...108,820,148
Ensembl chr12:108,792,973...108,820,148
JBrowse link
Alcohol-Induced Sudden Cardiac Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 pyrophosphatase (inorganic) 2 ISO ClinVar Annotator: match by term: Sudden cardiac failure, alcohol-induced ClinVar
OMIM
PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 PMID:30384889 NCBI chr 3:133,310,059...133,378,235
Ensembl chr 3:133,310,110...133,378,235
JBrowse link
cardiac arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 treatment ISO RGD PMID:26010685 RGD:12791997 NCBI chr 7:46,104,523...46,180,039
Ensembl chr 7:46,104,523...46,180,033
JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr 5:3,927,736...4,080,204
Ensembl chr 5:3,928,054...4,081,310
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 IMP RGD PMID:20363892 RGD:5509101 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Ank2 ankyrin 2, brain ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532 PMID:28600387 NCBI chr 3:126,921,607...127,500,347
Ensembl chr 3:126,921,612...127,499,350
JBrowse link
G Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:21383000 PMID:22840528 PMID:25527503 PMID:28492532 NCBI chr 5:15,934,264...16,374,511
Ensembl chr 5:15,934,691...16,374,511
JBrowse link
G Cacnb2 calcium channel, voltage-dependent, beta 2 subunit ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:14,603,861...14,988,811
Ensembl chr 2:14,603,088...14,987,908
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO protein:increased expression:hippocampus (rat) RGD PMID:19756023 RGD:4889980 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cep85l centrosomal protein 85-like ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 PMID:22137083 PMID:23861362 PMID:24033266 PMID:25611685 PMID:25741868 PMID:26535225 PMID:27532257 PMID:28492532 PMID:28600387 NCBI chr10:53,273,441...53,379,883
Ensembl chr10:53,273,443...53,379,947
JBrowse link
G Dpp6 dipeptidylpeptidase 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr 5:26,817,357...27,727,500
Ensembl chr 5:26,817,203...27,727,505
JBrowse link
G Dsc2 desmocollin 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:18678517 PMID:23861362 PMID:24033266 PMID:24704780 PMID:25637381 PMID:25741868 PMID:27153395 PMID:28492532 NCBI chr18:20,030,633...20,059,554
Ensembl chr18:20,030,633...20,059,554
JBrowse link
G Dsg2 desmoglein 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:20400443 PMID:23861362 PMID:24070718 PMID:25741868 PMID:28492532 PMID:28600387 NCBI chr18:20,558,074...20,604,526
Ensembl chr18:20,558,074...20,604,521
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:21606390 PMID:25525159 PMID:25741868 PMID:28492532 NCBI chr13:38,151,294...38,198,577
Ensembl chr13:38,151,294...38,198,577
JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO RGD PMID:9522364 RGD:13208524 NCBI chr 5:115,297,110...115,300,990
Ensembl chr 5:115,297,110...115,300,999
JBrowse link
G Ep300 E1A binding protein p300 ISO associated with Diabetes Mellitus; mRNA:increased expression:blood (human) RGD PMID:19577077 RGD:2312286 NCBI chr15:81,586,209...81,652,077
Ensembl chr15:81,585,351...81,652,077
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic IMP RGD PMID:17728042 RGD:5688386 NCBI chr14:66,084,372...66,124,522
Ensembl chr14:66,084,374...66,124,500
JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532 NCBI chr 9:58,822,949...58,863,175
Ensembl chr 9:58,823,412...58,863,175
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:9806674 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il18 interleukin 18 ISO RGD PMID:18679114 RGD:4889454 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Ins2 insulin II ISO CTD Direct Evidence: therapeutic CTD PMID:17449947 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 ISO protein:increased expression:cerebellum (rat) RGD PMID:21859719 RGD:6480675 NCBI chr 6:108,213,083...108,551,116
Ensembl chr 6:108,213,096...108,551,109
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr 6:142,564,837...142,571,614
Ensembl chr 6:142,564,837...142,571,614
JBrowse link
G Mybpc3 myosin binding protein C, cardiac ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:14563344 PMID:15519027 PMID:16352453 PMID:20624503 PMID:22361390 PMID:23140321 PMID:23299917 PMID:23785128 PMID:24033266 PMID:24503780 PMID:24510615 PMID:25163546 PMID:25741868 PMID:28492532 NCBI chr 2:91,118,114...91,136,516
Ensembl chr 2:91,118,144...91,136,516
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927
JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr17:71,003,332...71,126,856
Ensembl chr17:71,002,633...71,126,856
JBrowse link
G Nsun6 NOL1/NOP2/Sun domain family member 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:14,990,444...15,055,144
Ensembl chr 2:14,995,131...15,055,069
JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 PMID:22137083 PMID:23861362 PMID:24033266 PMID:25611685 PMID:25741868 PMID:26535225 PMID:27532257 PMID:28492532 PMID:28600387 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987
JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:22004663 PMID:24033266 PMID:24503780 PMID:25637381 PMID:25741868 PMID:27896284 PMID:28492532 NCBI chr19:53,660,989...53,867,083
Ensembl chr19:53,677,306...53,867,080
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr13:11,553,099...12,106,945
Ensembl chr13:11,553,102...12,106,945
JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12354768 PMID:12820704 PMID:15466642 PMID:15840476 PMID:16540748 PMID:17161064 PMID:17210839 PMID:18071069 PMID:18452873 PMID:19412328 PMID:20403459 PMID:20875080 PMID:22378279 PMID:22581653 PMID:23008441 PMID:23098067 PMID:24033266 PMID:24653702 PMID:25741868 PMID:26209461 PMID:26467025 PMID:26749013 PMID:27287068 PMID:28265756 PMID:28492532 PMID:28781330 PMID:29032884 NCBI chr 9:119,483,404...119,579,030
Ensembl chr 9:119,483,408...119,579,016
JBrowse link
G Slmap sarcolemma associated protein ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr14:26,413,168...26,534,624
Ensembl chr14:26,413,168...26,534,931
JBrowse link
G Sod1 superoxide dismutase 1, soluble IDA RGD PMID:15843790 RGD:1581221 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9806674, PMID:18679114 RGD:4889454 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 treatment ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:26010685 RGD:12791997 NCBI chr 7:45,303,155...45,334,071
Ensembl chr 7:45,302,632...45,333,780
JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868 PMID:28492532 NCBI chr14:20,929,383...21,033,676
Ensembl chr14:20,929,398...21,033,676
JBrowse link
Cardiac Edema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22865611 NCBI chr 6:55,336,299...55,348,555
Ensembl chr 6:55,336,432...55,348,555
JBrowse link
G Ift122 intraflagellar transport 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20493458 NCBI chr 6:115,853,379...115,926,699
Ensembl chr 6:115,853,470...115,926,699
JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23533172 NCBI chr 4:148,434,495...148,444,760
Ensembl chr 4:148,434,495...148,444,771
JBrowse link
Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO protein:increased expression:kidney tubule: RGD PMID:23220287, PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr11:46,739,822...46,779,578
Ensembl chr11:46,735,080...46,779,578
JBrowse link
Cor pulmonale term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21450080 RGD:6767563 NCBI chr17:34,597,460...34,600,937
Ensembl chr17:34,597,862...34,600,936
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 ISO RGD PMID:20669672 RGD:4143386 NCBI chr 8:94,772,180...94,782,427
Ensembl chr 8:94,772,009...94,782,427
JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:20669672 RGD:4143386 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
diastolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 severity
susceptibility
treatment
ISO DNS:insertion/deletion:intron: (rs1799752)
DNA:insertion/deletion:intron 16:
RGD PMID:19752885, PMID:19021695, PMID:14757777 RGD:40400704, RGD:40400906, RGD:40400723 NCBI chr11:105,967,948...105,989,964
Ensembl chr11:105,967,945...105,989,964
JBrowse link
G Adra1d adrenergic receptor, alpha 1d ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 2:131,545,357...131,562,497
Ensembl chr 2:131,545,850...131,562,283
JBrowse link
G Akip1 A kinase (PRKA) interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:109,703,678...109,712,186
Ensembl chr 7:109,703,690...109,712,189
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:70,344,147...70,390,538
Ensembl chr11:70,344,152...70,352,031
JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:36,530,193...36,536,556
Ensembl chr 1:36,530,193...36,539,429
Ensembl chr 1:36,530,193...36,539,429
JBrowse link
G Apln apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:48,025,146...48,034,853
Ensembl chr  X:48,025,146...48,034,853
JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 2:131,186,436...131,198,511
Ensembl chr 2:131,186,949...131,198,497
JBrowse link
G Col4a1 collagen, type IV, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 8:11,198,423...11,312,889
Ensembl chr 8:11,198,423...11,312,826
JBrowse link
G Col6a1 collagen, type VI, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:76,708,792...76,726,044
Ensembl chr10:76,708,792...76,726,168
JBrowse link
G Col8a1 collagen, type VIII, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr16:57,624,256...57,754,737
Ensembl chr16:57,624,258...57,754,737
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:165,763,758...165,775,309
Ensembl chr 1:165,763,746...165,775,308
JBrowse link
G Cyrib CYFIP related Rac1 interactor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr15:63,929,094...64,060,778
Ensembl chr15:63,929,097...64,060,478
JBrowse link
G Elk3 ELK3, member of ETS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:93,247,415...93,311,159
Ensembl chr10:93,247,414...93,311,135
JBrowse link
G Epn3 epsin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:94,489,599...94,499,974
Ensembl chr11:94,489,599...94,499,974
JBrowse link
G Fhl1 four and a half LIM domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:56,731,209...56,793,346
Ensembl chr  X:56,731,787...56,793,346
JBrowse link
G Fibin fin bud initiation factor homolog (zebrafish) ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 2:110,360,925...110,362,993
Ensembl chr 2:110,360,917...110,363,183
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:31,070,535...31,076,697
Ensembl chr 7:31,068,172...31,076,704
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:30,942,368...30,944,029
Ensembl chr 7:30,942,368...30,944,032
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 9:21,766,773...21,798,546
Ensembl chr 9:21,766,784...21,798,744
JBrowse link
G Klf9 Kruppel-like factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr19:23,141,226...23,168,129
Ensembl chr19:23,141,226...23,168,134
JBrowse link
G Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr19:11,469,353...11,487,182
Ensembl chr19:11,469,366...11,482,192
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626
JBrowse link
G Nppa natriuretic peptide type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:126,623,246...126,625,470
Ensembl chr 7:126,623,249...126,630,861
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:3,319,241...3,342,971
Ensembl chr11:3,330,401...3,342,971
JBrowse link
G Plxnd1 plexin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 6:115,954,811...115,995,339
Ensembl chr 6:115,954,811...115,995,005
JBrowse link
G Ptp4a2 protein tyrosine phosphatase 4a2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:129,811,165...129,850,003
Ensembl chr 4:129,811,219...129,850,003
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:57,190,841...57,339,040
Ensembl chr 4:57,190,841...57,301,837
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 8:23,411,383...23,449,632
Ensembl chr 8:23,411,502...23,449,632
JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr12:82,169,377...82,451,786
Ensembl chr12:82,169,320...82,451,786
JBrowse link
G Trdn triadin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:33,083,483...33,476,709
Ensembl chr10:33,080,554...33,476,709
JBrowse link
G Wdr45 WD repeat domain 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:7,721,987...7,728,201
Ensembl chr  X:7,714,333...7,728,206
JBrowse link
G Zfp532 zinc finger protein 532 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr18:65,580,230...65,689,443
Ensembl chr18:65,579,912...65,689,443
JBrowse link
Neonatal Pulmonary Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cps1 carbamoyl-phosphate synthetase 1 susceptibility ISO ClinVar Annotator: match by term: Pulmonary hypertension, neonatal, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11407344 PMID:14718356 PMID:15465784 PMID:16708072 PMID:17310273 PMID:20154341 PMID:21120950 PMID:21767969 PMID:25741868 PMID:28492532 NCBI chr 1:67,122,426...67,231,267
Ensembl chr 1:67,123,026...67,231,259
JBrowse link
Paroxysmal Dyspnea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:21388992 RGD:5129099 NCBI chr 1:134,199,215...134,235,457
Ensembl chr 1:134,199,223...134,235,431
JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO ClinVar Annotator: match by term: Asthma, nocturnal, susceptibility to ClinVar PMID:7706471 PMID:9399946 PMID:9399966 PMID:9522789 PMID:11739457 PMID:14557466 PMID:15500895 PMID:15867853 PMID:16596417 PMID:28492532 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
primary pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IEA OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr10:75,316,877...75,334,792
Ensembl chr10:75,316,877...75,334,784
JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) ISO
IEA
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Pulmonary hypertension, primary, dexfenfluramine-associated
ClinVar Annotator: match by term: Pulmonary hypertension, primary, fenfluramine-associated
ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension
OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344
CTD
ClinVar
MouseDO
PMID:11015450 PMID:11115378 PMID:12358323 PMID:16429395 PMID:16429403 PMID:16717148 PMID:16728714 PMID:19324947 PMID:19555857 PMID:20096498 PMID:20534176 PMID:21801371 PMID:24033266 PMID:25460361 PMID:25741868 PMID:26387786 PMID:26820968 PMID:28492532 PMID:32581362 NCBI chr 1:59,764,279...59,878,081
Ensembl chr 1:59,763,400...59,879,014
JBrowse link
G Cav1 caveolin 1, caveolae protein ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Foxf1 forkhead box F1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:19500772 PMID:19592680 PMID:19812545 PMID:20425831 PMID:22766610 PMID:23034409 PMID:23074687 PMID:23335808 PMID:23505205 PMID:23943206 PMID:24033266 PMID:24842713 PMID:26462560 NCBI chr 8:121,084,386...121,088,154
Ensembl chr 8:121,084,386...121,088,144
JBrowse link
G Hdac1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 4:129,516,104...129,542,646
Ensembl chr 4:129,516,104...129,542,713
JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 1:91,928,779...92,195,702
Ensembl chr 1:91,928,779...92,195,699
JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr11:102,195,747...102,230,172
Ensembl chr11:102,194,432...102,230,166
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO protein:decreased expression:lung, wall of arteriole (human) RGD PMID:20522807 RGD:9686087 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Kcnk3 potassium channel, subfamily K, member 3 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 5:30,588,170...30,625,270
Ensembl chr 5:30,588,170...30,625,271
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma IEA OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Smad9 SMAD family member 9 ISO
IEA
CTD Direct Evidence: marker/mechanism
OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344
CTD
MouseDO
NCBI chr 3:54,755,455...54,801,662
Ensembl chr 3:54,755,582...54,801,257
JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 IEA OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 1:161,395,438...161,418,206
Ensembl chr 1:161,395,409...161,418,410
JBrowse link
G Vip vasoactive intestinal polypeptide IEA OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr10:5,639,193...5,647,617
Ensembl chr10:5,639,218...5,647,617
JBrowse link
Primary Pulmonary Hypertension, 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:9245985 PMID:12700602 PMID:14684682 PMID:15024723 PMID:15879500 PMID:15880681 PMID:16429404 PMID:16470787 PMID:16540754 PMID:16705692 PMID:18159113 PMID:19555857 PMID:20414677 PMID:20501893 PMID:21158752 PMID:22632830 PMID:23298310 PMID:23722869 PMID:24753439 PMID:25741868 PMID:26387786 PMID:27316748 PMID:28492532 PMID:29449337 PMID:32581362 NCBI chr15:101,128,522...101,145,336
Ensembl chr15:101,128,522...101,145,336
JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia
ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1
ClinVar
OMIM
PMID:3291115 PMID:10903931 PMID:10973254 PMID:11015450 PMID:11115378 PMID:11502704 PMID:12045205 PMID:12139571 PMID:12358323 PMID:12446270 PMID:12821254 PMID:14516151 PMID:14583445 PMID:14985116 PMID:15055271 PMID:15059534 PMID:15146475 PMID:15170098 PMID:15358693 PMID:15591269 PMID:15687131 PMID:15775752 PMID:15965979 PMID:16429395 PMID:16429403 PMID:16717148 PMID:16728714 PMID:18159113 PMID:18221724 PMID:18356561 PMID:18364108 PMID:18386374 PMID:18503968 PMID:18792970 PMID:19206171 PMID:19223935 PMID:19324947 PMID:19555857 PMID:19844076 PMID:20002458 PMID:20095988 PMID:20096498 PMID:20496075 PMID:20534176 PMID:21070126 PMID:21228398 PMID:21737554 PMID:21801371 PMID:22632830 PMID:22995991 PMID:23139147 PMID:23298310 PMID:23579436 PMID:23592887 PMID:23675998 PMID:24033266 PMID:24591673 PMID:24853021 PMID:24936649 PMID:25429696 PMID:25612240 PMID:25688877 PMID:25741868 PMID:25917481 PMID:26387786 PMID:27453251 PMID:27630060 PMID:27884767 PMID:28388887 PMID:28492532 PMID:28507310 PMID:29631995 PMID:29650961 PMID:29743074 PMID:29843651 PMID:30029678 PMID:30578397 PMID:32581362 NCBI chr 1:59,764,279...59,878,081
Ensembl chr 1:59,763,400...59,879,014
JBrowse link
G Eng endoglin ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:18498373 PMID:23298310 PMID:24033266 PMID:25741868 PMID:26167679 PMID:26387786 PMID:28492532 PMID:30029678 NCBI chr 2:32,646,595...32,682,669
Ensembl chr 2:32,646,595...32,682,669
JBrowse link
G Gm26287 predicted gene, 26287 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:23579436 PMID:26387786 NCBI chr 1:59,704,258...59,704,338
Ensembl chr 1:59,704,258...59,704,338
JBrowse link
G Gm26293 predicted gene, 26293 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:23579436 PMID:26387786 NCBI chr 1:59,692,509...59,692,592
Ensembl chr 1:59,692,509...59,692,592
JBrowse link
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:20018952 PMID:21685056 PMID:23861362 PMID:24068186 PMID:25076992 PMID:28492532 NCBI chr 6:126,532,551...126,535,555
Ensembl chr 6:126,532,551...126,535,412
JBrowse link
G Kcnk3 potassium channel, subfamily K, member 3 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:23883380 NCBI chr 5:30,588,170...30,625,270
Ensembl chr 5:30,588,170...30,625,271
JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:23579436 PMID:26387786 NCBI chr 1:59,684,961...59,711,510
Ensembl chr 1:59,684,971...59,719,044
JBrowse link
G Smad1 SMAD family member 1 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:21898662 PMID:26387786 NCBI chr 8:79,338,395...79,399,428
Ensembl chr 8:79,338,395...79,399,518
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:21898662 PMID:24728327 PMID:25502805 PMID:25741868 PMID:26387786 PMID:28492532 NCBI chr18:73,634,790...73,703,791
Ensembl chr18:73,639,009...73,703,780
JBrowse link
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar NCBI chr 3:54,755,455...54,801,662
Ensembl chr 3:54,755,582...54,801,257
JBrowse link
G Snord11 small nucleolar RNA, C/D box 11 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:23579436 PMID:26387786 NCBI chr 1:59,704,808...59,704,870
Ensembl chr 1:59,704,790...59,704,873
JBrowse link
G Snord70 small nucleolar RNA, C/D box 70 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:23579436 PMID:26387786 NCBI chr 1:59,691,958...59,692,010
Ensembl chr 1:59,691,934...59,692,020
JBrowse link
G Tbx4 T-box 4 ISO ClinVar Annotator: match by term: Pulmonary Hypertension, Primary, 1 ClinVar PMID:25741868 PMID:31151956 NCBI chr11:85,886,367...85,916,097
Ensembl chr11:85,886,422...85,916,097
JBrowse link
Primary Pulmonary Hypertension, 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 2
ClinVar Annotator: match by OMIM:615342
OMIM
ClinVar
PMID:19211612 PMID:21898662 PMID:21920918 PMID:24033266 PMID:28492532 NCBI chr 3:54,755,455...54,801,662
Ensembl chr 3:54,755,582...54,801,257
JBrowse link
Primary Pulmonary Hypertension, 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor, type 1B ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 3 ClinVar PMID:25741868 NCBI chr 3:141,837,135...142,169,585
Ensembl chr 3:141,837,136...142,169,425
JBrowse link
G Cav1 caveolin 1, caveolae protein ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 3
ClinVar Annotator: match by OMIM:615343
OMIM
ClinVar
PMID:22474227 PMID:25741868 PMID:26387786 PMID:28492532 PMID:29231014 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
Primary Pulmonary Hypertension, 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium channel, subfamily K, member 3 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 4
ClinVar Annotator: match by OMIM:615344
OMIM
ClinVar
PMID:23883380 PMID:25741868 PMID:26387786 PMID:28492532 NCBI chr 5:30,588,170...30,625,270
Ensembl chr 5:30,588,170...30,625,271
JBrowse link
Sudden Cardiac Death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 disease_progression ISO RGD PMID:22661490 RGD:13831296 NCBI chr 1:78,657,825...78,707,743
Ensembl chr 1:78,657,825...78,707,743
JBrowse link
G Adra2b adrenergic receptor, alpha 2b ISO RGD PMID:12535806 RGD:1559314 NCBI chr 2:127,363,179...127,367,221
Ensembl chr 2:127,363,208...127,367,221
JBrowse link
G Akap9 A kinase (PRKA) anchor protein (yotiao) 9 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr 5:3,927,736...4,080,204
Ensembl chr 5:3,928,054...4,081,310
JBrowse link
G Ank2 ankyrin 2, brain ISO ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
ClinVar PMID:25741868 PMID:28492532, PMID:12571597 RGD:734572 NCBI chr 3:126,921,607...127,500,347
Ensembl chr 3:126,921,612...127,499,350
JBrowse link
G Apob apolipoprotein B ISO RGD PMID:17045270 RGD:1601197 NCBI chr12:7,977,629...8,016,839
Ensembl chr12:7,977,648...8,016,835
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 6:118,587,240...119,197,384
Ensembl chr 6:118,587,240...119,196,890
Ensembl chr 6:118,587,240...119,196,890
JBrowse link
G Cep85l centrosomal protein 85-like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 PMID:22137083 PMID:23861362 PMID:24033266 PMID:25611685 PMID:25741868 PMID:26535225 PMID:27532257 PMID:28492532 PMID:28600387 NCBI chr10:53,273,441...53,379,883
Ensembl chr10:53,273,443...53,379,947
JBrowse link
G Dpp6 dipeptidylpeptidase 6 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 5:26,817,357...27,727,500
Ensembl chr 5:26,817,203...27,727,505
JBrowse link
G Dsp desmoplakin ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:20435227 PMID:25741868 NCBI chr13:38,151,294...38,198,577
Ensembl chr13:38,151,294...38,198,577
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP RGD PMID:22093512 RGD:12910124 NCBI chr10:56,377,300...56,390,419
Ensembl chr10:56,377,330...56,402,513
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362 PMID:27930701 PMID:28492532 NCBI chr 9:114,899,339...114,933,987
Ensembl chr 9:114,899,341...114,933,987
JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:21615589 PMID:23623143 PMID:23861362 PMID:24033266 PMID:24569893 PMID:25145517 PMID:25467552 PMID:25642760 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 9:58,822,949...58,863,175
Ensembl chr 9:58,823,412...58,863,175
JBrowse link
G Il6 interleukin 6 susceptibility ISO RGD PMID:23906927 RGD:12792237 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itgb3 integrin beta 3 ISO associated with arteriosclerosis; DNA:polymorphism:exon RGD PMID:20846430 RGD:5128476 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar PMID:18508782 PMID:19716085 PMID:22581653 PMID:25417810 PMID:25741868 PMID:26704558 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Kng2 kininogen 2 susceptibility ISO DNA:SNPs: : RGD PMID:19716087 RGD:10411885 NCBI chr16:22,985,852...23,029,101
Ensembl chr16:22,985,854...23,029,482
JBrowse link
G Lmna lamin A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15996213 NCBI chr 3:88,481,148...88,509,932
Ensembl chr 3:88,480,147...88,509,956
JBrowse link
G mt-Tp tRNA proline, mitochondrial ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:1379415 PMID:1645537 PMID:8511015 PMID:22638997 PMID:25741868 PMID:29760464 PMID:30236074 NCBI chr MT:15,356...15,422
Ensembl chr MT:15,356...15,422
JBrowse link
G mt-Tt tRNA threonine, mitochondrial ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:1379415 PMID:1645537 PMID:8511015 PMID:22638997 PMID:25741868 PMID:29760464 PMID:30236074 NCBI chr MT:15,289...15,355
Ensembl chr MT:15,289...15,355
JBrowse link
G Mybpc3 myosin binding protein C, cardiac ISO CTD Direct Evidence: marker/mechanism CTD PMID:20435227 NCBI chr 2:91,118,114...91,136,516
Ensembl chr 2:91,118,144...91,136,516
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:15998695 PMID:20215591 PMID:22194935 PMID:22361390 PMID:23299917 PMID:23861362 PMID:24033266 PMID:24119082 PMID:25741868 PMID:27194543 PMID:28088328 PMID:28492532 NCBI chr14:54,941,921...54,968,017
Ensembl chr14:54,941,921...54,966,927
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626
JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24033266 PMID:28492532 NCBI chr17:71,003,332...71,126,856
Ensembl chr17:71,002,633...71,126,856
JBrowse link
G Nebl nebulette ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 2:17,342,673...17,734,949
Ensembl chr 2:17,343,909...17,731,464
JBrowse link
G Pkp2 plakophilin 2 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 PMID:27532257 PMID:28492532 NCBI chr16:16,213,345...16,272,712
Ensembl chr16:16,213,318...16,272,712
JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993 PMID:16235537 PMID:17655857 PMID:21167350 PMID:21332051 PMID:22137083 PMID:23861362 PMID:24033266 PMID:25611685 PMID:25741868 PMID:26535225 PMID:27532257 PMID:28492532 PMID:28600387 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:23861362 PMID:24033266 PMID:25650408 PMID:25741868 PMID:26656175 PMID:27054166 PMID:27930701 PMID:28492532 PMID:31913406 NCBI chr13:11,553,099...12,106,945
Ensembl chr13:11,553,102...12,106,945
JBrowse link
G Scn3b sodium channel, voltage-gated, type III, beta ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 9:40,269,216...40,291,618
Ensembl chr 9:40,269,217...40,291,618
JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar PMID:15851227 PMID:16712702 PMID:18378609 PMID:18508782 PMID:19564561 PMID:19841300 PMID:20129283 PMID:22581653 PMID:22984773 PMID:23631430 PMID:23671135 PMID:23861362 PMID:24033266 PMID:24055113 PMID:25741868 PMID:25904541 PMID:28492532 PMID:30254039 PMID:32533946 NCBI chr 9:119,483,404...119,579,030
Ensembl chr 9:119,483,408...119,579,016
JBrowse link
G Sp4 trans-acting transcription factor 4 IAGP RGD PMID:11007485 RGD:1580019 NCBI chr12:118,231,686...118,301,440
Ensembl chr12:118,234,933...118,301,440
JBrowse link
G Tmem43 transmembrane protein 43 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac arrest
CTD
ClinVar
PMID:20435227 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 6:91,473,707...91,488,463
Ensembl chr 6:91,473,703...91,488,463
JBrowse link
G Tnni3 troponin I, cardiac 3 ISO ClinVar Annotator: match by term: Sudden cardiac arrest ClinVar PMID:21839045 PMID:25741868 NCBI chr 7:4,518,305...4,522,718
Ensembl chr 7:4,518,305...4,524,229
JBrowse link
G Tnnt2 troponin T2, cardiac ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:17556660 PMID:23233322 PMID:24033266 PMID:24503780 PMID:25741868 PMID:28492532 NCBI chr 1:135,836,315...135,852,268
Ensembl chr 1:135,836,354...135,852,260
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24019741 PMID:28492532 NCBI chr 7:45,303,155...45,334,071
Ensembl chr 7:45,302,632...45,333,780
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
ClinVar PMID:19608031 PMID:24033266 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 2:76,703,980...76,982,557
Ensembl chr 2:76,703,980...76,982,547
JBrowse link
Sudden Cardiac Failure, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 pyrophosphatase (inorganic) 2 ISO ClinVar Annotator: match by term: Sudden cardiac failure, infantile ClinVar
OMIM
PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 PMID:30384889 NCBI chr 3:133,310,059...133,378,235
Ensembl chr 3:133,310,110...133,378,235
JBrowse link
systolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 (cardiac muscle) ISO ClinVar Annotator: match by term: Heart failure, systolic ClinVar PMID:19525294 PMID:23299917 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr19:36,111,965...36,119,844
Ensembl chr19:36,111,961...36,120,099
JBrowse link
G Bmp10 bone morphogenetic protein 10 ISO CTD Direct Evidence: therapeutic CTD PMID:31712309 NCBI chr 6:87,428,994...87,434,512
Ensembl chr 6:87,428,994...87,437,677
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Systolic heart failure ClinVar PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr13:38,151,294...38,198,577
Ensembl chr13:38,151,294...38,198,577
JBrowse link
G Hspa1a heat shock protein 1A disease_progression ISO protein:increased expression:serum: RGD PMID:23564583 RGD:7257646 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Nppb natriuretic peptide type B ISO associated with Renal Insufficiency;protein:increased expression:plasma: RGD PMID:23725445, PMID:23122795 RGD:7246908, RGD:7247627 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Heart failure, systolic ClinVar PMID:23861362 PMID:24033266 PMID:25163546 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 2:76,703,980...76,982,557
Ensembl chr 2:76,703,980...76,982,547
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13465
    disease of anatomical entity 12944
      cardiovascular system disease 3551
        heart disease 2536
          congestive heart failure 391
            Cardiac Edema 3
            Cardio-Renal Syndrome 1
            Cor pulmonale + 29
            Paroxysmal Dyspnea 2
            cardiac arrest + 57
            diastolic heart failure 34
            rheumatic congestive heart failure 0
            systolic heart failure 6
paths to the root