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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:panic disorder
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Accession:DOID:594 term browser browse the term
Definition:An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress. (DO)
Synonyms:exact_synonym: Panic Attack;   Panic Attacks;   Panic Disorders;   panic anxiety syndrome
 narrow_synonym: PAND1;   PAND2;   PAND3;   panic disorder 1;   panic disorder 2;   panic disorder 3;   panic disorder with joint laxity;   panic disorder without agoraphobia
 related_synonym: PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 13q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 4q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 9q-RELATED;   catechol-o-methyltransferase polymorphism
 primary_id: MESH:D016584
 alt_id: OMIM:167870;   OMIM:607853;   OMIM:609985
 xref: EFO:0004262;   EFO:1001907;   ICD10CM:F41.0;   NCI:C34890;   OMIM:PS167870
For additional species annotation, visit the Alliance of Genome Resources.



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panic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor IEA GAD PMID:15118671 RGD:1331525 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADORA2A adenosine A2a receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:12825092 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G ADRA2A adrenoceptor alpha 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:14656453 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G CCKBR cholecystokinin B receptor IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:8878350 PMID:15354400 RGD:1358454 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127
JBrowse link
G COMT catechol-O-methyltransferase IAGP
EXP
ClinVar Annotator: match by term: CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:7304673 PMID:7585135 PMID:8807664 PMID:8886163 PMID:8941353 More... NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G CRH corticotropin releasing hormone IAGP RGD PMID:14675801 RGD:1358525 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO
IAGP
RGD PMID:21421022 PMID:20817074 RGD:5683630, RGD:5683631 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
JBrowse link
G INS insulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:12073167 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G MANEA mannosidase endo-alpha susceptibility IAGP associated with substance dependence; DNA:SNP:3'utr: (rs1133503) (Human) RGD PMID:24473444 RGD:401851911 NCBI chr 6:95,577,535...95,609,452
Ensembl chr 6:95,577,485...95,609,470
JBrowse link
G MAOA monoamine oxidase A IAGP RGD PMID:15670397 RGD:1600723 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:polymorphism: : RGD PMID:24856568 RGD:12910826 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G TPH2 tryptophan hydroxylase 2 susceptibility IAGP DNA:SNP:intron: (rs1386494) (human) RGD PMID:17123728 RGD:5686356 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 41189
    disease of anatomical entity 32344
      nervous system disease 26233
        central nervous system disease 23468
          brain disease 21902
            disease of mental health 17210
              cognitive disorder 5504
                anxiety disorder 122
                  panic disorder 12
                    Panic Disorder with Bladder Conditions 0
                    Panic Disorder with Joint Laxity 0
                    panic disorder with agoraphobia + 0
paths to the root