RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: panic disorder
Accession: DOID:594
browse the term
Definition: An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress. (DO)
Synonyms: exact_synonym: Panic Attack; Panic Attacks; Panic Disorders; panic anxiety syndrome
narrow_synonym: PAND1; PAND2; PAND3; panic disorder 1; panic disorder 2; panic disorder 3; panic disorder with joint laxity; panic disorder without agoraphobia
related_synonym: PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 13q-RELATED; PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 4q-RELATED; PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 9q-RELATED; catechol-o-methyltransferase polymorphism
primary_id: MESH:D016584
alt_id: OMIM:167870 ; OMIM:607853 ; OMIM:609985
xref: EFO:0004262 ; EFO:1001907 ; ICD10CM:F41.0 ; NCI:C34890 ; OMIM:PS167870
For additional species annotation, visit the
Alliance of Genome Resources .
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ADORA1
adenosine A1 receptor
IEA
GAD
PMID:15118671
RGD:1331525
NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
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ADORA2A
adenosine A2a receptor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:12825092
NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
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ADRA2A
adrenoceptor alpha 2A
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:14656453
NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
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CCKBR
cholecystokinin B receptor
IAGP EXP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:8878350 PMID:15354400
RGD:1358454
NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127
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COMT
catechol-O-methyltransferase
IAGP EXP
ClinVar Annotator: match by term: CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM CTD Direct Evidence: marker/mechanism
ClinVar CTD
PMID:7304673 PMID:7585135 PMID:8807664 PMID:8886163 PMID:8941353 PMID:9110364 PMID:10395222 PMID:10459407 PMID:11171904 PMID:11381111 PMID:11502905 PMID:11772685 PMID:11925305 PMID:12192614 PMID:12359690 PMID:12402217 PMID:12436243 PMID:12595695 PMID:12611827 PMID:12716966 PMID:12842306 PMID:14966473 PMID:15169701 PMID:15457404 PMID:15457497 PMID:15645182 PMID:15652872 PMID:15821730 PMID:15824744 PMID:15935994 PMID:16043133 PMID:16130008 PMID:16135635 PMID:16275815 PMID:16513880 PMID:16542388 PMID:17504906 PMID:21280081 PMID:25741868 More...
NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
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CRH
corticotropin releasing hormone
IAGP
RGD
PMID:14675801
RGD:1358525
NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
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HTR1A
5-hydroxytryptamine receptor 1A
ISO IAGP
RGD
PMID:21421022 PMID:20817074
RGD:5683630 , RGD:5683631
NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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INS
insulin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:12073167
NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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MANEA
mannosidase endo-alpha
susceptibility
IAGP
associated with substance dependence; DNA:SNP:3'utr: (rs1133503) (Human)
RGD
PMID:24473444
RGD:401851911
NCBI chr 6:95,577,535...95,609,452
Ensembl chr 6:95,577,485...95,609,470
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MAOA
monoamine oxidase A
IAGP
RGD
PMID:15670397
RGD:1600723
NCBI chr X:43,655,006...43,746,817
Ensembl chr X:43,654,907...43,746,817
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MBL2
mannose binding lectin 2
susceptibility
IAGP
DNA:polymorphism: :
RGD
PMID:24856568
RGD:12910826
NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
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TPH2
tryptophan hydroxylase 2
susceptibility
IAGP
DNA:SNP:intron: (rs1386494) (human)
RGD
PMID:17123728
RGD:5686356
NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
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