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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:panic disorder
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Accession:DOID:594 term browser browse the term
Definition:An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress. (DO)
Synonyms:exact_synonym: Panic Attack;   Panic Attacks;   Panic Disorders;   panic anxiety syndrome
 narrow_synonym: PAND1;   PAND2;   PAND3;   panic disorder 1;   panic disorder 2;   panic disorder 3;   panic disorder with joint laxity;   panic disorder without agoraphobia
 related_synonym: PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 13q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 4q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 9q-RELATED;   catechol-o-methyltransferase polymorphism
 primary_id: MESH:D016584
 alt_id: OMIM:167870;   OMIM:607853;   OMIM:609985
 xref: EFO:0004262;   EFO:1001907;   ICD10CM:F41.0;   NCI:C34890;   OMIM:PS167870
For additional species annotation, visit the Alliance of Genome Resources.

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panic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505 		JBrowse link
G Adra2a adrenoceptor alpha 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:14656453 NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240 		JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:8878350 PMID:15354400 RGD:1358454 NCBI chrNW_004955414:22,001,351...22,011,275
Ensembl chrNW_004955414:22,000,436...22,011,433 		JBrowse link
G Comt catechol-O-methyltransferase ISO ClinVar Annotator: match by term: CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM ClinVar PMID:7304673 PMID:7585135 PMID:8807664 PMID:8886163 PMID:8941353 More... NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412 		JBrowse link
G Crh corticotropin releasing hormone ISO RGD PMID:14675801 RGD:1358525 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:20817074 PMID:21421022 RGD:5683630 RGD:5683631 NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146 		JBrowse link
G Ins insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12073167 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419 		JBrowse link
G Manea mannosidase endo-alpha susceptibility ISO associated with substance dependence; DNA:SNP:3'utr: (rs1133503) (Human) RGD PMID:24473444 RGD:401851911 NCBI chrNW_004955411:21,729,085...21,763,684
Ensembl chrNW_004955411:21,735,550...21,761,750 		JBrowse link
G Maoa amine oxidase [flavin-containing] A ISO RGD PMID:15670397 RGD:1600723 NCBI chrNW_004955516:4,494,133...4,576,317
Ensembl chrNW_004955516:4,493,946...4,576,317 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphism: : RGD PMID:24856568 RGD:12910826 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
G Tph2 tryptophan hydroxylase 2 susceptibility ISO DNA:SNP:intron: (rs1386494) (human) RGD PMID:17123728 RGD:5686356 NCBI chrNW_004955405:11,877,474...11,981,035
Ensembl chrNW_004955405:11,886,206...11,982,550 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16063
    disease of anatomical entity 13820
      nervous system disease 12088
        central nervous system disease 10855
          brain disease 10186
            disease of mental health 7327
              cognitive disorder 1967
                anxiety disorder 108
                  panic disorder 11
                    Panic Disorder with Bladder Conditions 0
                    Panic Disorder with Joint Laxity 0
                    panic disorder with agoraphobia + 0
paths to the root