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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:panic disorder
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Accession:DOID:594 term browser browse the term
Definition:A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
Synonyms:exact_synonym: PAND1;   PAND2;   PAND3;   PANIC DISORDER 2;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 4q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 9q-RELATED;   Panic Attack;   Panic Attacks;   Panic Disorders;   panic anxiety syndrome;   panic disorder 1;   panic disorder 3
 primary_id: MESH:D016584
 alt_id: OMIM:167870;   OMIM:607853;   OMIM:609985;   RDO:0006976
 xref: ICD10CM:F41.0;   NCI:C34890
For additional species annotation, visit the Alliance of Genome Resources.

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panic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adra2a adrenoceptor alpha 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:14656453 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8878350, PMID:15354400 RGD:1358454 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Comt catechol-O-methyltransferase ISO ClinVar Annotator: match by term: CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM OMIM
PMID:7304673 PMID:7585135 PMID:8886163 PMID:10459407 PMID:11381111 PMID:11502905 PMID:11925305 PMID:12611827 PMID:12716966 PMID:15457404 PMID:15645182 PMID:15652872 PMID:15821730 PMID:15824744 PMID:16043133 PMID:16395295 PMID:16513880 PMID:16542388 PMID:17156920 PMID:17548664 PMID:18192898 PMID:19094200 PMID:19514130 PMID:21398039 PMID:22695756 PMID:22992668 PMID:23210659 PMID:23302985 PMID:23459442 PMID:23686330 PMID:23773341 PMID:24533707 PMID:25155931 PMID:25185591 PMID:25741868 PMID:26555332 PMID:26902643 PMID:27027462 PMID:28006928 PMID:28346387 PMID:28745577 PMID:29259946 PMID:29474345 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crh corticotropin releasing hormone ISO RGD PMID:14675801 RGD:1358525 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IMP
RGD PMID:21421022, PMID:20817074 RGD:5683630, RGD:5683631 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12073167 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Maoa monoamine oxidase A ISO RGD PMID:15670397 RGD:1600723 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphism: : RGD PMID:24856568 RGD:12910826 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Tph2 tryptophan hydroxylase 2 susceptibility ISO DNA:SNP:intron: (rs1386494) (human) RGD PMID:17123728 RGD:5686356 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link

Term paths to the root
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  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        central nervous system disease 10353
          brain disease 9712
            disease of mental health 7022
              cognitive disorder 1949
                anxiety disorder 166
                  panic disorder 11
                    Panic Disorder with Bladder Conditions 0
                    Panic Disorder with Joint Laxity 0
paths to the root