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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:ovarian hyperstimulation syndrome
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Accession:DOID:5425 term browser browse the term
Definition:An ovarian disease that is characterized by cystic enlargement of the ovaries and a fluid shift from the intravascular to the third space and has_symptom abdominal pain, has_symptom nausea and has_symptom vomiting. This disease is an iatrogenic complication of assisted reproduction technology. (DO)
Synonyms:exact_synonym: OHSS;   Ovarian Hyperstimulation Syndromes;   ovarian hyperstimulation syndrome, familial gestational spontaneous;   ovarian response to FSH stimulation;   secondary Meig's syndrome
 primary_id: MESH:D016471
 alt_id: OMIM:276400;   OMIM:608115
For additional species annotation, visit the Alliance of Genome Resources.


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ovarian hyperstimulation syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 treatment ISO RGD PMID:25217874 RGD:13506956 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G F3 coagulation factor III, tissue factor severity ISO protein:increased expression:plasma RGD PMID:12695751 RGD:11340210 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G FSHR follicle stimulating hormone receptor ISO ClinVar Annotator: match by term: Ovarian hyperstimulation syndrome | ClinVar Annotator: match by term: Ovarian response to FSH stimulation OMIM
ClinVar		 PMID:8894317 PMID:9402264 PMID:9769327 PMID:10022448 PMID:11036902 More... NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum, ascites (human) RGD PMID:9322101 RGD:11062135 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G KDR kinase insert domain receptor treatment ISO RGD PMID:25151950 RGD:126925217 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO OMIM:608115 MouseDO NCBI chr11:47,195,122...47,215,277
Ensembl chr11:47,748,353...47,768,672 		JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO human protein in a mouse model RGD PMID:23295464 RGD:8635395 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568 		JBrowse link
G TFPI tissue factor pathway inhibitor severity ISO protein:decreased expression:plasma RGD PMID:12695751 RGD:11340210 NCBI chr2B:74,744,154...74,834,338
Ensembl chr2B:192,541,881...192,581,384 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO RGD PMID:25151950 RGD:126925217 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17996
    syndrome 10168
      ovarian hyperstimulation syndrome 9
Path 2
Term Annotations click to browse term
  disease 17996
    disease of anatomical entity 15260
      Urogenital Diseases 4727
        Female Urogenital Diseases and Pregnancy Complications 2329
          Female Urogenital Diseases 1917
            female reproductive system disease 1914
              Adnexal Diseases 882
                ovarian disease 873
                  ovarian hyperstimulation syndrome 9
paths to the root