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Term:ovarian hyperstimulation syndrome
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Accession:DOID:5425 term browser browse the term
Definition:A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.
Synonyms:exact_synonym: OHSS;   Ovarian Hyperstimulation Syndrome, Familial Gestational Spontaneous;   Ovarian Hyperstimulation Syndromes;   Ovarian response to FSH stimulation;   secondary Meig's syndrome
 primary_id: MESH:D016471;   RDO:0006959
 alt_id: OMIM:608115
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ovarian hyperstimulation syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:13506956
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:11340210
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:1601236
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11062135
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:13592920
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:8635395
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:11340210

Term paths to the root
Path 1
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  disease 15553
    syndrome 5224
      ovarian hyperstimulation syndrome 7
Path 2
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  disease 15553
    disease of anatomical entity 14837
      Urogenital Diseases 3998
        Female Urogenital Diseases and Pregnancy Complications 1756
          Female Urogenital Diseases 1466
            female reproductive system disease 1462
              Adnexal Diseases 653
                ovarian disease 647
                  ovarian hyperstimulation syndrome 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.