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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:borna disease
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Accession:DOID:5154 term browser browse the term
Definition:An encephalomyelitis of horses, sheep and cattle caused by BORNA DISEASE VIRUS.
Synonyms:exact_synonym: enzootic encephalomyelitis
 primary_id: MESH:D001890
 alt_id: RDO:0005035
For additional species annotation, visit the Alliance of Genome Resources.


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borna disease term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoc aldolase, fructose-bisphosphate C IEP mRNA, protein:decreased expression:cerebellum, Purkinje cell RGD PMID:17182680 RGD:2301132 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Atf4 activating transcription factor 4 IEP protein:increased expression:cerebellum RGD PMID:16912310 RGD:32733622 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 IEP protein:increased expression:cerebellum, hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) IEP RGD PMID:16612977 RGD:2289373 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP RGD PMID:12053272 RGD:4891998 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA:increased expression:brain RGD PMID:12053272 RGD:4891998 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP mRNA,protein:increased expression:cerebellum, hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A IEP protein:increased expression:cerebellum,hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068 		JBrowse link
G Gja1 gap junction protein, alpha 1 IEP RGD PMID:18538309 RGD:7364785 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjb6 gap junction protein, beta 6 IEP RGD PMID:18538309 RGD:7364785 NCBI chr15:31,284,562...31,295,010
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Il16 interleukin 16 IEP protein:increased expression:brain RGD PMID:14698845 RGD:1354526 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Mif macrophage migration inhibitory factor IEP protein:increased expression:astrocyte RGD PMID:11870869 RGD:1642006 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mt3 metallothionein 3 IEP RGD PMID:16612977 RGD:2289373 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase IEP mRNA:decreased expression:hippocampus RGD PMID:18057239 RGD:2316738 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IEP mRNA,protein:increased expression,increased activity:neuron, glial cell: RGD PMID:18057239 RGD:2316738 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G S100b S100 calcium binding protein B IEP protein:decreased expression:cerebellum, cerebral cortex RGD PMID:17376896 RGD:5508841 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 IEP protein:increased expression:brain (rat) RGD PMID:12106671 RGD:38549588 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Xbp1 X-box binding protein 1 IEP mRNA,protein:altered expression:cerebellum,hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18030
    Animal Diseases 1686
      borna disease 18
Path 2
Term Annotations click to browse term
  disease 18030
    disease of anatomical entity 17410
      nervous system disease 13079
        central nervous system disease 11253
          Central Nervous System Infections 282
            borna disease 18
paths to the root