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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:borna disease
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Accession:DOID:5154 term browser browse the term
Definition:An encephalomyelitis of horses, sheep and cattle caused by BORNA DISEASE VIRUS.
Synonyms:exact_synonym: enzootic encephalomyelitis
 primary_id: MESH:D001890
 alt_id: RDO:0005035
For additional species annotation, visit the Alliance of Genome Resources.

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borna disease term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoc aldolase, fructose-bisphosphate C IEP mRNA, protein:decreased expression:cerebellum, Purkinje cell RGD PMID:17182680 RGD:2301132 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Atf4 activating transcription factor 4 IEP protein:increased expression:cerebellum RGD PMID:16912310 RGD:32733622 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 IEP protein:increased expression:cerebellum, hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Cd44 CD44 molecule (Indian blood group) IEP RGD PMID:16612977 RGD:2289373 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP RGD PMID:12053272 RGD:4891998 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA:increased expression:brain RGD PMID:12053272 RGD:4891998 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP mRNA,protein:increased expression:cerebellum, hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A IEP protein:increased expression:cerebellum,hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Gja1 gap junction protein, alpha 1 IEP RGD PMID:18538309 RGD:7364785 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb6 gap junction protein, beta 6 IEP RGD PMID:18538309 RGD:7364785 NCBI chr15:37,400,888...37,411,656
Ensembl chr15:37,400,889...37,410,848
JBrowse link
G Il16 interleukin 16 IEP protein:increased expression:brain RGD PMID:14698845 RGD:1354526 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Mif macrophage migration inhibitory factor IEP protein:increased expression:astrocyte RGD PMID:11870869 RGD:1642006 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mt3 metallothionein 3 IEP RGD PMID:16612977 RGD:2289373 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase IEP mRNA:decreased expression:hippocampus RGD PMID:18057239 RGD:2316738 NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IEP mRNA,protein:increased expression,increased activity:neuron, glial cell: RGD PMID:18057239 RGD:2316738 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G S100b S100 calcium binding protein B IEP protein:decreased expression:cerebellum, cerebral cortex RGD PMID:17376896 RGD:5508841 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IEP protein:increased expression:brain (rat) RGD PMID:12106671 RGD:38549588 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Xbp1 X-box binding protein 1 IEP mRNA,protein:altered expression:cerebellum,hippocampus RGD PMID:16912310 RGD:32733622 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16158
    Animal Diseases 1653
      borna disease 18
Path 2
Term Annotations click to browse term
  disease 16158
    disease of anatomical entity 15408
      nervous system disease 11007
        central nervous system disease 9126
          Central Nervous System Infections 202
            borna disease 18
paths to the root