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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:melioidosis
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Accession:DOID:5052 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain. (DO)
Synonyms:exact_synonym: Nightcliff gardener's disease;   Whitmore's disease;   acute and fulminating melioidosis;   melioidoses;   pseudoglanders;   subacute and chronic melioidosis
 related_synonym: melioidosis, resistance to;   melioidosis, susceptibility to
 primary_id: MESH:D008554
 alt_id: MIM:615557
 xref: GARD:9546;   ICD10CM:A24.9;   ICD9CM:025;   NCI:C128336
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
melioidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifna1 interferon alpha 1 ISO mRNA:increased expression:PBMC RGD PMID:28435890 RGD:36174031 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:19114913 RGD:36049801 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Plaur plasminogen activator, urokinase receptor IMP RGD PMID:20142364 RGD:6484129 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 severity ISO
IMP 		protein:increased expression:plasma (human) RGD PMID:23992406 PMID:23992406 PMID:25370187 RGD:36174010, RGD:36174010, RGD:36174011 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527 		JBrowse link
G Tlr5 toll-like receptor 5 susceptibility ISO mRNA:increased expression:blood, monocyte, granulocyte (human)
ClinVar Annotator: match by term: Melioidosis, resistance to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:17676990 RGD:5129511 NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity
treatment 		ISO
IEP
IDA 		RGD PMID:18008257 PMID:18008257 PMID:18008257 RGD:126928120, RGD:126928120, RGD:126928120 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16271
    disease by infectious agent 2240
      Bacterial Infections and Mycoses 1087
        bacterial infectious disease 832
          primary bacterial infectious disease 197
            melioidosis 6
Path 2
Term Annotations click to browse term
  disease 16271
    disease by infectious agent 2240
      Bacterial Infections and Mycoses 1087
        bacterial infectious disease 832
          Gram-Negative Bacterial Infections 201
            Burkholderia Infections 6
              melioidosis 6
paths to the root