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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:melioidosis
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Accession:DOID:5052 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain. (DO)
Synonyms:exact_synonym: Nightcliff gardener's disease;   Whitmore's disease;   acute and fulminating melioidosis;   melioidoses;   pseudoglanders;   subacute and chronic melioidosis
 related_synonym: melioidosis, resistance to;   melioidosis, susceptibility to
 primary_id: MESH:D008554
 alt_id: MIM:615557
 xref: GARD:9546;   ICD10CM:A24.9;   ICD9CM:025;   NCI:C128336
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
melioidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNA1 interferon alpha 1 IEP mRNA:increased expression:PBMC RGD PMID:28435890 RGD:36174031 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 IEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:19114913 RGD:36049801 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEP mRNA, protein:increased expression:blood, granulocyte, monocyte RGD PMID:20142364 RGD:6484129 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G SERPINF1 serpin family F member 1 severity IEP
ISO 		protein:increased expression:plasma (human) RGD PMID:23992406 PMID:25370187 PMID:23992406 RGD:36174010, RGD:36174011, RGD:36174010 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G TLR5 toll like receptor 5 susceptibility IEP
IAGP
EXP 		mRNA:increased expression:blood, monocyte, granulocyte (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melioidosis, resistance to 		OMIM
CTD
ClinVar
RGD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:17676990 RGD:5129511 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 severity
treatment 		IEP
ISO 		RGD PMID:18008257 PMID:18008257 PMID:18008257 RGD:126928120, RGD:126928120, RGD:126928120 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 151016
    disease by infectious agent 8266
      Bacterial Infections and Mycoses 2031
        bacterial infectious disease 1646
          primary bacterial infectious disease 514
            melioidosis 6
Path 2
Term Annotations click to browse term
  disease 151016
    disease by infectious agent 8266
      Bacterial Infections and Mycoses 2031
        bacterial infectious disease 1646
          Gram-Negative Bacterial Infections 234
            Burkholderia Infections 6
              melioidosis 6
paths to the root