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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:melioidosis
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Accession:DOID:5052 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain. (DO)
Synonyms:exact_synonym: Nightcliff gardener's disease;   Whitmore's disease;   acute and fulminating melioidosis;   melioidoses;   pseudoglanders;   subacute and chronic melioidosis
 related_synonym: melioidosis, resistance to;   melioidosis, susceptibility to
 primary_id: MESH:D008554
 alt_id: MIM:615557
 xref: GARD:9546;   ICD10CM:A24.9;   ICD9CM:025;   NCI:C128336
For additional species annotation, visit the Alliance of Genome Resources.


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melioidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRAK3 interleukin 1 receptor associated kinase 3 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:19114913 RGD:36049801 NCBI chr12:22,661,613...22,721,203
Ensembl chr12:23,168,346...23,227,148 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO mRNA, protein:increased expression:blood, granulocyte, monocyte RGD PMID:20142364 RGD:6484129 NCBI chr19:40,588,100...40,616,479
Ensembl chr19:49,197,341...49,222,561
Ensembl chr19:49,197,341...49,222,561 		JBrowse link
G SERPINF1 serpin family F member 1 severity ISO protein:increased expression:plasma (human) RGD PMID:23992406 PMID:25370187 RGD:36174010 RGD:36174011 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568 		JBrowse link
G TLR5 toll like receptor 5 susceptibility ISO ClinVar Annotator: match by term: Melioidosis, resistance to ClinVar
OMIM		 PMID:14623910 PMID:16027372 PMID:23447684 NCBI chr 1:198,787,046...198,819,537
Ensembl chr 1:203,798,767...203,801,343 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 severity
treatment 		ISO RGD PMID:18008257 RGD:126928120 NCBI chr 6:40,861,283...40,874,446
Ensembl chr 6:42,163,337...42,183,091 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15838
    disease by infectious agent 2147
      Bacterial Infections and Mycoses 1055
        bacterial infectious disease 801
          primary bacterial infectious disease 186
            melioidosis 5
Path 2
Term Annotations click to browse term
  disease 15838
    disease by infectious agent 2147
      Bacterial Infections and Mycoses 1055
        bacterial infectious disease 801
          Gram-Negative Bacterial Infections 187
            Burkholderia Infections 5
              melioidosis 5
paths to the root