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ONTOLOGY REPORT - ANNOTATIONS


Term:esophageal cancer
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Accession:DOID:5041 term browser browse the term
Definition:A gastrointestinal system cancer that is located in the esophagus.
Synonyms:exact_synonym: Ca lower third oesophagus;   Ca middle third oesophagus;   esophagus cancer;   malignant neoplasm of distal third of esophagus;   malignant neoplasm of lower third of oesophagus;   malignant neoplasm of middle third of oesophagus;   malignant neoplasm of proximal third of esophagus;   malignant neoplasm of upper third esophagus;   malignant tumor of Distal Third of esophagus;   malignant tumor of Proximal Third of esophagus;   malignant tumor of abdominal esophagus;   malignant tumor of the middle Third of the esophagus
 related_synonym: ESOPHAGEAL CANCER, ALCOHOL-RELATED, SUSCEPTIBILITY TO
 primary_id: OMIM:133239
 alt_id: RDO:9002298
 xref: GARD:6383;   ICD10CM:C15.3;   ICD10CM:C15.4;   ICD10CM:C15.5;   ICD9CM:150.2;   ICD9CM:150.3;   ICD9CM:150.4;   ICD9CM:150.5;   ICD9CM:150.8;   NCI:C3028;   NCI:C3533;   NCI:C3534;   NCI:C3535;   NCI:C4764
For additional species annotation, visit the Alliance of Genome Resources.


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esophageal cancer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh2 aldehyde dehydrogenase 2, mitochondrial JBrowse link 5 121,566,027 121,593,824 RGD:8554872
G Brca2 breast cancer 2, early onset JBrowse link 5 150,522,297 150,570,147 RGD:8554872
G Ctnna1 catenin (cadherin associated protein), alpha 1 JBrowse link 18 35,118,902 35,254,776 RGD:2289811
G Cxcl1 chemokine (C-X-C motif) ligand 1 JBrowse link 5 90,891,245 90,893,121 RGD:5134997
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:14700950
RGD:11554919
G Dcc deleted in colorectal carcinoma JBrowse link 18 71,253,613 72,351,228 RGD:7240710
G Gstm1 glutathione S-transferase, mu 1 JBrowse link 3 108,012,250 108,017,979 RGD:14700950
RGD:14700969
RGD:14700964
RGD:11554919
G Gstt1 glutathione S-transferase, theta 1 JBrowse link 10 75,783,813 75,798,584 RGD:14700969
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:4145286
G Il5 interleukin 5 JBrowse link 11 53,720,794 53,725,103 RGD:5134997
G Lzts1 leucine zipper, putative tumor suppressor 1 JBrowse link 8 69,132,659 69,184,249 RGD:1600104
RGD:7240710
G Maf avian musculoaponeurotic fibrosarcoma oncogene homolog JBrowse link 8 115,703,253 115,706,894 RGD:8554872
G Mxi1 MAX interactor 1, dimerization protein JBrowse link 19 53,310,128 53,373,293 RGD:1298988
G Rnf6 ring finger protein (C3H2C3 type) 6 JBrowse link 5 146,209,193 146,221,457 RGD:7240710
G Tgfbr2 transforming growth factor, beta receptor II JBrowse link 9 116,087,695 116,175,363 RGD:7240710
RGD:8554872
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:8554872
G Wwox WW domain-containing oxidoreductase JBrowse link 8 114,439,635 115,352,712 RGD:7240710
RGD:8554872
Barrett's adenocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 19 37,697,738 37,701,536 RGD:13782259
esophageal carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 breast cancer 2, early onset JBrowse link 5 150,522,297 150,570,147 RGD:8554872
G Cdkn2a cyclin dependent kinase inhibitor 2A JBrowse link 4 89,274,473 89,294,619 RGD:8554872
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:8554872
G Dcc deleted in colorectal carcinoma JBrowse link 18 71,253,613 72,351,228 RGD:8554872
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:8554872
G Ep300 E1A binding protein p300 JBrowse link 15 81,586,209 81,652,077 RGD:8554872
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 11 98,412,484 98,437,716 RGD:8554872
G Fbxw7 F-box and WD-40 domain protein 7 JBrowse link 3 84,814,990 84,979,198 RGD:8554872
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 7 130,162,451 130,266,808 RGD:8554872
G Hras Harvey rat sarcoma virus oncogene JBrowse link 7 141,189,934 141,194,019 RGD:8554872
G Kras Kirsten rat sarcoma viral oncogene homolog JBrowse link 6 145,216,699 145,250,420 RGD:8554872
G Lrrc56 leucine rich repeat containing 56 JBrowse link 7 141,194,111 141,210,055 RGD:8554872
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,059 32,468,486 RGD:8554872
G Rhoa ras homolog family member A JBrowse link 9 108,306,160 108,337,943 RGD:8554872
G Smad4 SMAD family member 4 JBrowse link 18 73,634,790 73,703,791 RGD:8554872
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:8554872
esophagus adenocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid1a AT rich interactive domain 1A (SWI-like) JBrowse link 4 133,679,008 133,756,769 RGD:11554173
G Barx1 BarH-like homeobox 1 JBrowse link 13 48,663,036 48,666,507 RGD:11554173
G Becn1 beclin 1, autophagy related JBrowse link 11 101,288,258 101,302,286 RGD:11561943
G Cdc5l cell division cycle 5-like (S. pombe) JBrowse link 17 45,391,887 45,433,707 RGD:10047052
G Cdkn2a cyclin dependent kinase inhibitor 2A JBrowse link 4 89,274,473 89,294,619 RGD:11554173
G Crtc1 CREB regulated transcription coactivator 1 JBrowse link 8 70,382,352 70,439,702 RGD:11554173
G Ctsb cathepsin B JBrowse link 14 63,122,462 63,145,923 RGD:734853
G Dock2 dedicator of cyto-kinesis 2 JBrowse link 11 34,226,815 34,783,905 RGD:11554173
G Elmo1 engulfment and cell motility 1 JBrowse link 13 20,090,507 20,608,353 RGD:11554173
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 JBrowse link 7 19,344,067 19,356,524 RGD:13207314
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:8662425
G Foxp1 forkhead box P1 JBrowse link 6 98,925,342 99,522,746 RGD:11554173
RGD:11535321
G Gstm1 glutathione S-transferase, mu 1 JBrowse link 3 108,012,250 108,017,979 RGD:12792242
G Gstt1 glutathione S-transferase, theta 1 JBrowse link 10 75,783,813 75,798,584 RGD:12792242
G Mmp12 matrix metallopeptidase 12 JBrowse link 9 7,344,397 7,360,461 RGD:7207058
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) JBrowse link 9 7,464,141 7,476,869 RGD:7207058
G Mmp3 matrix metallopeptidase 3 JBrowse link 9 7,445,822 7,455,975 RGD:7207058
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:13204790
G Nell1 NEL-like 1 JBrowse link 7 49,975,350 50,863,289 RGD:11554173
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,059 32,468,486 RGD:11554173
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 2 36,216,742 36,258,593 RGD:5687745
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:11554173
RGD:13207437
G Smad4 SMAD family member 4 JBrowse link 18 73,634,790 73,703,791 RGD:11554173
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:2317403
G Spg20 spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) JBrowse link 3 55,112,108 55,137,332 RGD:11554173
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:11554173
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:11554173
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor JBrowse link 15 97,854,427 97,908,296 RGD:11055189
RGD:13432070
esophagus small cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Krt14 keratin 14 JBrowse link 11 100,203,162 100,207,510 RGD:1600174
esophagus squamous cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azin1 antizyme inhibitor 1 JBrowse link 15 38,487,430 38,519,294 RGD:14700707
G Bmp6 bone morphogenetic protein 6 JBrowse link 13 38,345,716 38,500,314 RGD:7242413
G Brca2 breast cancer 2, early onset JBrowse link 5 150,522,297 150,570,147 RGD:11344913
G Bst2 bone marrow stromal cell antigen 2 JBrowse link 8 71,534,255 71,537,472 RGD:14398496
G Cbx8 chromobox 8 JBrowse link 11 119,036,303 119,040,913 RGD:9587436
G Cdkn2b cyclin dependent kinase inhibitor 2B JBrowse link 4 89,306,289 89,311,032 RGD:7248756
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:8554872
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:14700943
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:7829715
G Dcc deleted in colorectal carcinoma JBrowse link 18 71,253,613 72,351,228 RGD:734879
G Dnmt3b DNA methyltransferase 3B JBrowse link 2 153,649,411 153,687,730 RGD:9589085
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:5131486
RGD:8554872
G Ehmt1 euchromatic histone methyltransferase 1 JBrowse link 2 24,790,769 24,919,643 RGD:9589143
RGD:9590071
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 JBrowse link 17 34,898,463 34,914,073 RGD:9590071
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 JBrowse link 7 19,344,067 19,356,524 RGD:11252162
G Fanca Fanconi anemia, complementation group A JBrowse link 8 123,266,294 123,318,651 RGD:11344913
G Gstm1 glutathione S-transferase, mu 1 JBrowse link 3 108,012,250 108,017,979 RGD:14700943
RGD:14700982
RGD:14700948
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:14700982
G Gstt1 glutathione S-transferase, theta 1 JBrowse link 10 75,783,813 75,798,584 RGD:14700948
RGD:14700982
G Hoxb7 homeobox B7 JBrowse link 11 96,285,604 96,290,163 RGD:10402177
G Kat2b K(lysine) acetyltransferase 2B JBrowse link 17 53,566,774 53,672,721 RGD:9590307
G Kdm4c lysine (K)-specific demethylase 4C JBrowse link 4 74,242,497 74,405,864 RGD:9587746
RGD:9587752
G Kdm5b lysine (K)-specific demethylase 5B JBrowse link 1 134,560,178 134,632,878 RGD:9587776
G Kdm6a lysine (K)-specific demethylase 6A JBrowse link X 18,160,862 18,279,936 RGD:9588233
G Kmt2c lysine (K)-specific methyltransferase 2C JBrowse link 5 25,271,795 25,498,855 RGD:9588233
G Kmt2d lysine (K)-specific methyltransferase 2D JBrowse link 15 98,831,669 98,874,077 RGD:9588233
G Krt16 keratin 16 JBrowse link 11 100,246,091 100,248,902 RGD:633113
G Lzts1 leucine zipper, putative tumor suppressor 1 JBrowse link 8 69,132,659 69,184,249 RGD:8554872
G Mbd4 methyl-CpG binding domain protein 4 JBrowse link 6 115,840,697 115,853,400 RGD:9588976
RGD:9588980
G Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) JBrowse link 17 34,182,030 34,187,330 RGD:6482249
G Rnf6 ring finger protein (C3H2C3 type) 6 JBrowse link 5 146,209,193 146,221,457 RGD:8554872
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 JBrowse link 7 126,672,865 126,690,443 RGD:1581448
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) JBrowse link 17 34,187,556 34,197,225 RGD:6482249
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) JBrowse link 17 34,204,479 34,216,321 RGD:6482249
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:14995932
G Wwox WW domain-containing oxidoreductase JBrowse link 8 114,439,635 115,352,712 RGD:1599874
RGD:8554872
palmoplantar keratoderma-esophageal carcinoma syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rhbdf2 rhomboid 5 homolog 2 JBrowse link 11 116,598,148 116,627,019 RGD:7240710
RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12616
    disease of cellular proliferation 5637
      cancer 4074
        organ system cancer 3899
          gastrointestinal system cancer 1137
            esophageal cancer 80
              esophageal carcinoma + 71
              esophageal neuroendocrine tumor 0
              esophagus lymphoma 0
              esophagus melanoma 0
              esophagus sarcoma + 0
              malignant granular cell esophageal tumor 0
              neurofibroma of the esophagus 0
              palmoplantar keratoderma-esophageal carcinoma syndrome 1
Path 2
Term Annotations click to browse term
  disease 12616
    disease of cellular proliferation 5637
      Neoplasms by Site 5003
        Digestive System Neoplasms 1770
          Gastrointestinal Neoplasms 1628
            Esophageal Neoplasms 142
              esophageal cancer 80
                esophageal carcinoma + 71
                esophageal neuroendocrine tumor 0
                esophagus lymphoma 0
                esophagus melanoma 0
                esophagus sarcoma + 0
                malignant granular cell esophageal tumor 0
                neurofibroma of the esophagus 0
                palmoplantar keratoderma-esophageal carcinoma syndrome 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.