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ONTOLOGY REPORT - ANNOTATIONS


Term:esophageal cancer
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Accession:DOID:5041 term browser browse the term
Definition:A gastrointestinal system cancer that is located in the esophagus.
Synonyms:exact_synonym: Ca lower third oesophagus;   Ca middle third oesophagus;   esophagus cancer;   malignant neoplasm of distal third of esophagus;   malignant neoplasm of lower third of oesophagus;   malignant neoplasm of middle third of oesophagus;   malignant neoplasm of proximal third of esophagus;   malignant neoplasm of upper third esophagus;   malignant tumor of Distal Third of esophagus;   malignant tumor of Proximal Third of esophagus;   malignant tumor of abdominal esophagus;   malignant tumor of the middle Third of the esophagus
 related_synonym: ESOPHAGEAL CANCER, ALCOHOL-RELATED, SUSCEPTIBILITY TO
 primary_id: OMIM:133239
 alt_id: RDO:9002298
 xref: GARD:6383;   ICD10CM:C15.3;   ICD10CM:C15.4;   ICD10CM:C15.5;   ICD9CM:150.2;   ICD9CM:150.3;   ICD9CM:150.4;   ICD9CM:150.5;   ICD9CM:150.8;   NCI:C3028;   NCI:C3533;   NCI:C3534;   NCI:C3535;   NCI:C4764
For additional species annotation, visit the Alliance of Genome Resources.


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esophageal cancer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:8554872
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:8554872
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:2289811
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:5134997
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:14700950
RGD:11554919
G Dcc DCC netrin 1 receptor JBrowse link 18 66,518,213 67,629,801 RGD:7240710
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700950
RGD:14700969
RGD:14700964
RGD:11554919
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:14700969
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145286
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:5134997
G Lzts1 leucine zipper tumor suppressor 1 JBrowse link 16 22,250,452 22,306,667 RGD:1600104
RGD:7240710
G Maf MAF bZIP transcription factor JBrowse link 19 48,179,826 48,200,995 RGD:8554872
G Mxi1 MAX interactor 1, dimerization protein JBrowse link 1 274,030,748 274,090,071 RGD:1298988
G Rnf6 ring finger protein 6 JBrowse link 12 10,574,168 10,583,196 RGD:7240710
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:7240710
RGD:8554872
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8554872
G Wwox WW domain-containing oxidoreductase JBrowse link 19 46,761,353 47,695,247 RGD:7240710
RGD:8554872
Barrett's adenocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:13782259
esophageal carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:8554872
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:8554872
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:8554872
G Dcc DCC netrin 1 receptor JBrowse link 18 66,518,213 67,629,801 RGD:8554872
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:8554872
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:8554872
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:8554872
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:8554872
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:8554872
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8554872
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:8554872
G Lrrc56 leucine rich repeat containing 56 JBrowse link 1 214,182,232 214,197,184 RGD:8554872
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:8554872
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:8554872
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:8554872
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8554872
esophagus adenocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid1a AT-rich interaction domain 1A JBrowse link 5 151,904,687 151,977,973 RGD:11554173
G Barx1 BARX homeobox 1 JBrowse link 17 14,824,721 14,828,196 RGD:11554173
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11561943
G Cdc5l cell division cycle 5-like JBrowse link 9 17,949,764 17,988,514 RGD:10047052
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:11554173
G Crtc1 CREB regulated transcription coactivator 1 JBrowse link 16 20,740,746 20,798,145 RGD:11554173
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:734853
G Dock2 dedicator of cytokinesis 2 JBrowse link 10 19,181,512 19,603,171 RGD:11554173
G Elmo1 engulfment and cell motility 1 JBrowse link 17 46,352,102 46,888,788 RGD:11554173
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:13207314
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:8662425
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:11554173
RGD:11535321
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:12792242
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:12792242
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207058
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:7207058
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:7207058
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:13204790
G Nell1 neural EGFL like 1 JBrowse link 1 105,348,577 106,218,970 RGD:11554173
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:11554173
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:5687745
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
RGD:13207437
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:2317403
G Spart spartin JBrowse link 2 144,522,382 144,548,968 RGD:11554173
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:11055189
RGD:13432070
esophagus small cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Krt14 keratin 14 JBrowse link 10 88,118,029 88,122,233 RGD:1600174
esophagus squamous cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azin1 antizyme inhibitor 1 JBrowse link 7 77,345,646 77,372,398 RGD:14700707
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:7242413
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:11344913
G Bst2 bone marrow stromal cell antigen 2 JBrowse link 16 19,938,781 19,942,353 RGD:14398496
G Cbx8 chromobox 8 JBrowse link 10 108,148,073 108,150,511 RGD:9587436
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:7248756
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:8554872
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:14700943
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:7829715
G Dcc DCC netrin 1 receptor JBrowse link 18 66,518,213 67,629,801 RGD:734879
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:9589085
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131486
RGD:8554872
G Ehmt1 euchromatic histone lysine methyltransferase 1 JBrowse link 3 1,966,974 2,123,858 RGD:9589143
RGD:9590071
G Ehmt2 euchromatic histone lysine methyltransferase 2 JBrowse link 20 4,576,033 4,592,980 RGD:9590071
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:11252162
G Fanca FA complementation group A JBrowse link 19 56,067,548 56,126,075 RGD:11344913
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700943
RGD:14700982
RGD:14700948
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:14700982
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:14700948
RGD:14700982
G Hoxb7 homeo box B7 JBrowse link 10 84,135,224 84,138,642 RGD:10402177
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:9590307
G Kdm4c lysine demethylase 4C JBrowse link 5 90,800,139 91,012,662 RGD:9587746
RGD:9587752
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:9587776
G Kmt2c lysine methyltransferase 2C JBrowse link 4
4
82,506
6,083,650
109,986
6,294,413
RGD:9588233
G Kmt2d lysine methyltransferase 2D JBrowse link 7 140,507,137 140,542,479 RGD:9588233
G Krt16 keratin 16 JBrowse link 10 88,149,210 88,152,167 RGD:633113
G Lzts1 leucine zipper tumor suppressor 1 JBrowse link 16 22,250,452 22,306,667 RGD:8554872
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase JBrowse link 4 147,744,673 147,756,462 RGD:9588976
RGD:9588980
G Psmb9 proteasome 20S subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:6482249
G Rnf6 ring finger protein 6 JBrowse link 12 10,574,168 10,583,196 RGD:8554872
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:1581448
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:6482249
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:6482249
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:14995932
G Uty ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome JBrowse link Y 1,065,274 1,206,127 RGD:9588233
G Wwox WW domain-containing oxidoreductase JBrowse link 19 46,761,353 47,695,247 RGD:1599874
RGD:8554872
palmoplantar keratoderma-esophageal carcinoma syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rhbdf2 rhomboid 5 homolog 2 JBrowse link 10 105,573,759 105,600,885 RGD:7240710
RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15602
    disease of cellular proliferation 5825
      cancer 4154
        organ system cancer 3966
          gastrointestinal system cancer 1157
            esophageal cancer 80
              esophageal carcinoma + 71
              esophageal neuroendocrine tumor 0
              esophagus lymphoma 0
              esophagus melanoma 0
              esophagus sarcoma + 0
              malignant granular cell esophageal tumor 0
              neurofibroma of the esophagus 0
              palmoplantar keratoderma-esophageal carcinoma syndrome 1
Path 2
Term Annotations click to browse term
  disease 15602
    disease of cellular proliferation 5825
      Neoplasms by Site 5206
        Digestive System Neoplasms 1818
          Gastrointestinal Neoplasms 1677
            Esophageal Neoplasms 142
              esophageal cancer 80
                esophageal carcinoma + 71
                esophageal neuroendocrine tumor 0
                esophagus lymphoma 0
                esophagus melanoma 0
                esophagus sarcoma + 0
                malignant granular cell esophageal tumor 0
                neurofibroma of the esophagus 0
                palmoplantar keratoderma-esophageal carcinoma syndrome 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.