Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:poliomyelitis
go back to main search page
Accession:DOID:4953 term browser browse the term
Definition:An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
Synonyms:exact_synonym: Epidemic Acute Poliomyelitis;   Infantile Paralysis;   Nonpoliovirus Poliomyelitis;   Polio;   Polio Encephalitis;   acute poliomyelitis;   polios;   preparalytic poliomyelitides;   preparalytic poliomyelitis
 primary_id: MESH:D011051
 xref: GARD:7413;   ICD10CM:A80;   ICD9CM:045;   NCI:C35550
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
poliomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PVR PVR cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:3020560 PMID:28446605 NCBI chr19:41,592,042...41,614,397
Ensembl chr19:50,196,980...50,217,006
JBrowse link
vestibular neuronitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRP C-reactive protein disease_progression ISO RGD PMID:14636287 RGD:9491594 NCBI chr 1:135,062,102...135,064,402 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13850
    disease of anatomical entity 13507
      Immune & Inflammatory Diseases 3378
        Inflammation 1916
          myelitis 26
            poliomyelitis 2
              herpes zoster oticus 0
              nonparalytic poliomyelitis 0
              paralytic poliomyelitis + 0
              postpoliomyelitis syndrome 0
              vestibular neuronitis 1
Path 2
Term Annotations click to browse term
  disease 13850
    disease of anatomical entity 13507
      nervous system disease 11185
        peripheral nervous system disease 2405
          neuropathy 2226
            neuromuscular disease 1755
              motor neuron disease 371
                poliomyelitis 2
                  herpes zoster oticus 0
                  nonparalytic poliomyelitis 0
                  paralytic poliomyelitis + 0
                  postpoliomyelitis syndrome 0
                  vestibular neuronitis 1
paths to the root