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ONTOLOGY REPORT - ANNOTATIONS
Term:brain edema
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Accession:DOID:4724 term browser browse the term
Definition:Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Synonyms:exact_synonym: Brain Swelling;   Brain Swellings;   Cerebral Edema;   Cerebral Edemas, Vasogenic;   Cytotoxic Brain Edema;   Cytotoxic Cerebral Edema;   Intracranial Edema;   Vasogenic Brain Edema;   Vasogenic Cerebral Edema;   intracranial swelling;   wet brain
 primary_id: MESH:D001929;   RDO:0001851
For additional species annotation, visit the Alliance of Genome Resources.

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brain edema term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:1598635
RGD:12791991
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:5148033
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:5148010
RGD:5490129
RGD:5490126
RGD:5490122
RGD:5148033
RGD:5148020
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:2300375
G C5 complement C5 JBrowse link 3
3		 14,049,993
14,206,466		 14,113,931
14,229,141		 RGD:1600655
G Cp ceruloplasmin JBrowse link 2 104,744,249 104,803,034 RGD:1599627
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:5135068
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:6771363
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:5490126
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:5490126
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:5490129
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10766444
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:4145390
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6771363
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5490126
RGD:11554173
G Myl9 myosin light chain 9 JBrowse link 3 152,857,573 152,863,961 RGD:11554173
G Mylk myosin light chain kinase JBrowse link 11 69,013,060 69,260,039 RGD:11554173
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:11554173
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:6483826
RGD:11554173
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6483826
RGD:11554173
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:5508832
RGD:11554173
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:2317927
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:8554891
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1580557
RGD:5148033
PEHO syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccdc88a coiled coil domain containing 88A JBrowse link 14 113,771,093 113,936,376 RGD:8554872
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:8548849
G Kif1a kinesin family member 1A JBrowse link 9 100,171,851 100,253,626 RGD:8554872
G Znhit3 zinc finger, HIT-type containing 3 JBrowse link 10 72,227,710 72,235,932 RGD:7240710
RGD:8554872
Progressive Encephalopathy, Early-Onset, with Brain Edema and/or Leukoencephalopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Naxe NAD(P)HX epimerase JBrowse link 2 187,424,319 187,426,410 RGD:8554872
Progressive Encephalopathy, Early-Onset, with Brain Edema and/or Leukoencephalopathy 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Naxe NAD(P)HX epimerase JBrowse link 2 187,424,319 187,426,410 RGD:7240710
RGD:8554872
Progressive Encephalopathy, Early-Onset, with Brain Edema and/or Leukoencephalopathy 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Naxd NAD(P)HX dehydratase JBrowse link 16 83,326,228 83,342,711 RGD:7240710
RGD:8554872
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15503
    Pathological Conditions, Signs and Symptoms 8038
      Signs and Symptoms 4692
        Edema 85
          brain edema 32
            PEHO syndrome 4
            Progressive Encephalopathy, Early-Onset, with Brain Edema and/or Leukoencephalopathy + 2
Path 2
Term Annotations click to browse term
  disease 15503
    disease of anatomical entity 14857
      nervous system disease 10273
        central nervous system disease 8410
          brain disease 7763
            brain edema 32
              PEHO syndrome 4
              Progressive Encephalopathy, Early-Onset, with Brain Edema and/or Leukoencephalopathy + 2
paths to the root

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