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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:endophthalmitis
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Accession:DOID:4692 term browser browse the term
Definition:Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.
Synonyms:exact_synonym: Endophthalmitides;   Infectious Endophthalmitides;   Infectious Endophthalmitis;   Ophthalmia;   Ophthalmias
 primary_id: MESH:D009877
 alt_id: RDO:0006235
 xref: NCI:C34586
For additional species annotation, visit the Alliance of Genome Resources.



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endophthalmitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor IEP protein:increased expression:retinal ganglion cell, bipolar cell of retina, photoreceptor (rat) RGD PMID:19039600 RGD:8662445 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Ifng interferon gamma IEP protein:increased expression:vitreous: RGD PMID:16544114 RGD:7829753 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:vitreous: RGD PMID:16544114 RGD:7829753 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor IEP associated with Staphylococcal Infections;protein:increased expression:cornea, retina, vitreous humor RGD PMID:18274645 RGD:9999421 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:19995266 PMID:22163046 RGD:8552880, RGD:8553060 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:vitreous: RGD PMID:16544114 RGD:7829753 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17286
    sensory system disease 5678
      eye disease 2765
        Eye Infections 59
          endophthalmitis 6
            gonococcal endophthalmia 0
            purulent endophthalmitis + 0
            suppurative uveitis + 0
Path 2
Term Annotations click to browse term
  disease 17286
    disease of anatomical entity 16621
      nervous system disease 12148
        sensory system disease 5678
          eye disease 2765
            globe disease 6
              endophthalmitis 6
                gonococcal endophthalmia 0
                purulent endophthalmitis + 0
                suppurative uveitis + 0
paths to the root