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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:large cell carcinoma
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Accession:DOID:4552 term browser browse the term
Definition:A tumor of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (From Dorland, 27th ed)
Synonyms:exact_synonym: Large Cell Carcinomas
 primary_id: MESH:D018287;   RDO:0007163
 xref: NCI:C3780
For additional species annotation, visit the Alliance of Genome Resources.


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large cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase severity ISO RGD PMID:20019837 RGD:2317441 NCBI chrNW_004955432:22,440,671...22,519,592
Ensembl chrNW_004955432:22,440,637...22,517,647
JBrowse link
G Prkca protein kinase C alpha ISO RGD PMID:9474241 RGD:2292463 NCBI chrNW_004955478:5,686,639...6,090,356
Ensembl chrNW_004955478:5,686,640...6,083,967
JBrowse link
G Strap serine/threonine kinase receptor associated protein ISO RGD PMID:16778189 RGD:1581429 NCBI chrNW_004955413:12,533,422...12,558,138
Ensembl chrNW_004955413:12,533,423...12,559,288
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12757
    disease of cellular proliferation 6160
      cancer 4460
        cell type cancer 3017
          carcinoma 2566
            large cell carcinoma 3
              Giant Cell Carcinoma + 0
              breast large cell neuroendocrine carcinoma 0
              cervical large cell neuroendocrine carcinoma 0
              large cell carcinoma with rhabdoid phenotype 0
              large cell neuroendocrine carcinoma + 0
              lung large cell carcinoma + 0
              ovarian large-cell neuroendocrine carcinoma 0
              thymus large cell carcinoma 0
paths to the root