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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:avian influenza
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Accession:DOID:4492 term browser browse the term
Definition:An influenza that results in infection located in respiratory tract of humans, domestic and wild birds, has_material_basis_in Influenza A virus, which is transmitted by contact with infected poultry. Five strains of avian influenza A viruses (H5N1, H7N3, H7N2, H7N7 and H9N2) are known to cause human infections. The infection has_symptom fever, has_symptom cough, has_symptom sore throat, has_symptom muscle aches, has_symptom nausea, has_symptom diarrhea, has_symptom vomiting, has_symptom neurologic changes, has_symptom pneumonia, and has_symptom acute respiratory distress. (DO)
Synonyms:exact_synonym: Avian Flu;   Fowl Plague;   avian influenzas;   bird flu;   influenza in bird;   influenza in birds
 primary_id: MESH:D005585
 xref: EFO:0005222;   ICD10CM:J09.X
For additional species annotation, visit the Alliance of Genome Resources.


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avian influenza term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 treatment
severity
ISO human protein in a mouse model RGD PMID:24800825 RGD:32716391 NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18613795 RGD:5135502 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 ameliorates ISO RGD PMID:28423682 RGD:127229942 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    Animal Diseases 1218
      Bird Diseases 4
        avian influenza 3
Path 2
Term Annotations click to browse term
  disease 16465
    disease by infectious agent 1964
      viral infectious disease 1498
        RNA Virus Infections 1264
          Orthomyxoviridae Infections 115
            influenza 112
              avian influenza 3
paths to the root