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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:allergic rhinitis
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Accession:DOID:4481 term browser browse the term
Definition:A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites. (DO)
Synonyms:exact_synonym: ALRH;   allergic rhinitides;   atopic rhinitis;   non-seasonal allergic rhinitis;   perenial allergic rhinitis;   pollenosis
 narrow_synonym: hay fever
 primary_id: MESH:D065631
 alt_id: OMIM:607154
 xref: EFO:0005854;   NCI:C34987;   NCI:C79532
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 severity ISO DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 no_association ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CCL11 chemokine (C-C motif) ligand 11 treatment ISO RGD PMID:23089405 RGD:7248414 NCBI chr12:40,779,906...40,782,862
Ensembl chr12:40,779,173...40,782,893 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr 3:10,381,306...10,385,677
Ensembl chr 3:10,381,306...10,385,677 		JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709 		JBrowse link
G CLDN3 claudin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr 3:11,019,073...11,020,102
Ensembl chr 3:11,019,073...11,020,102 		JBrowse link
G CLDN7 claudin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr12:52,612,517...52,628,376
Ensembl chr12:52,612,510...52,628,362 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103 		JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 4:88,948,357...88,956,513 JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr16:69,332,786...69,654,366
Ensembl chr16:69,332,587...69,655,380 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 8:46,078,122...46,247,144
Ensembl chr 8:46,078,276...46,241,914 		JBrowse link
G HRH1 histamine receptor H1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr13:67,209,261...67,411,174
Ensembl chr13:67,209,127...67,411,170 		JBrowse link
G IFNG interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism
associated with Asthma		 RGD
CTD		 PMID:12787306 PMID:18510219 PMID:29871060 RGD:10755770 RGD:7829803 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23253209 PMID:23883806 RGD:7364793 RGD:7364818 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL13 interleukin 13 susceptibility
no_association		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)		 OMIM
CTD
RGD		 PMID:12928861 RGD:8549516 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:94,402,665...94,455,609
Ensembl chr  X:94,402,676...94,439,060 		JBrowse link
G IL17A interleukin 17A susceptibility ISO DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)		 RGD PMID:21535180 PMID:22507625 RGD:5147409 RGD:9068429 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL18 interleukin 18 severity
no_association		 ISO DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)		 RGD PMID:22840759 RGD:8655914 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:8908280 PMID:9893928 PMID:14653048 PMID:24620662 RGD:11522769 RGD:7829796 RGD:7829802 RGD:7829827 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976 RGD:11522769 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212 		JBrowse link
G ITGB2 integrin subunit beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr13:207,514,281...207,544,108
Ensembl chr13:207,512,950...207,544,107 		JBrowse link
G LOC110258578 interleukin-1 beta-like ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199
G MUC1 mucin 1, cell surface associated severity ISO mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 RGD:127345100 NCBI chr 4:94,626,317...94,631,194 JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr 2:757,897...790,321 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G OCLN occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033 		JBrowse link
G PON1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,558,533...98,793,010 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr 2:9,297,282...9,302,204
Ensembl chr 2:9,297,283...9,302,165 		JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility ISO DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr 2:149,120,652...149,124,614
Ensembl chr 2:149,068,946...149,124,983 		JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SLA-8 MHC class I antigen 8 ISO RGD PMID:20487636 RGD:5144132 NCBI chr 7:23,622,352...23,625,818 JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 3:67,839,367...68,021,733
Ensembl chr 3:67,839,411...68,021,724 		JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TLR2 toll like receptor 2 severity ISO DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:		 RGD PMID:18219831 PMID:18381801 PMID:22402138 PMID:22555057 RGD:7800732 RGD:7800742 RGD:8552972 RGD:8552993 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR4 toll like receptor 4 no_association
treatment
susceptibility
severity		 ISO protein:increased expression:nasal lavage,leukocyte, bone marrow:
DNA:polymorphism: :4216G>C(human)
DNA:SNP: :rs1927911(human)
protein:decreased expression:nasal mucosa:
DNA:polymorphism:cds:p.D299G(human)		 RGD PMID:17069098 PMID:19763595 PMID:22402138 PMID:22555057 PMID:22577387 More... RGD:4145354 RGD:7800732 RGD:7800736 RGD:7800738 RGD:7800740 RGD:8552993 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR9 toll like receptor 9 ISO protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C49 cytochrome P450 2C49 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
Perennial Allergic Rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:serum RGD PMID:19725899 RGD:5686851 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19389874 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO protein:increased expression:nasal turbinate RGD PMID:19364335 RGD:5147461 NCBI chr11:7,371,328...7,438,111
Ensembl chr11:7,411,644...7,438,108 		JBrowse link
G CAT catalase ISO protein:decreased expression:plasma RGD PMID:20493834 RGD:5130771 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO protein:increased expression:nasal turbinate, mucosa (human) RGD PMID:9865755 RGD:8548839 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:Nasal Mucosa RGD PMID:17982926 RGD:4145109 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,285,012...29,376,343 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:17982926 RGD:4145109 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20226305 RGD:5132269 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CD86 CD86 molecule ISO protein:increased expression:nasal mucosa, dendritic cell (human) RGD PMID:17088138 RGD:4892343 NCBI chr13:138,427,573...138,504,307
Ensembl chr13:138,427,533...138,504,310 		JBrowse link
G CHIA chitinase acidic ISO mRNA, protein:increased expression:turbinate, mucosa (human) RGD PMID:20422678 RGD:5037226 NCBI chr 4:109,035,323...109,046,499
Ensembl chr 4:109,035,326...109,046,499 		JBrowse link
G EGR1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human) RGD PMID:19833116 RGD:5131984 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:17727088 RGD:4892590 NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858 		JBrowse link
G HMOX1 heme oxygenase 1 ISO mRNA, protein:increased expression: nasal mucosa RGD PMID:16540907 RGD:4145406
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:lung, endothelium (mouse)
protein:increased secretion:nasopharynx (human)		 RGD PMID:19047814 PMID:19968652 RGD:4145464 RGD:4145520 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 RGD:6480431 NCBI chr 1:27,037,151...27,061,095
Ensembl chr 1:27,037,165...27,061,093 		JBrowse link
G IL13 interleukin 13 ISO mRNA, protein:increased expression:nasal mucosa RGD PMID:8520776 RGD:4782826 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093 		JBrowse link
G IL17A interleukin 17A severity ISO protein:increased expression:serum RGD PMID:19226302 RGD:4889151 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL18 interleukin 18 susceptibility ISO DNA:SNP:promoter:c. -607A>C (rs1946518) (human) RGD PMID:16406079 RGD:4889924 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphism:exon:c.4845G>T (human) RGD PMID:14533660 RGD:4142859 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:18637763 RGD:5037238 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,915...52,288,485 		JBrowse link
G IL2 interleukin 2 ISO protein:decreased expression:serum: RGD PMID:17608155 RGD:8662959 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4 interleukin 4 treatment ISO protein:increased expression:serum RGD PMID:9237816 PMID:15329007 PMID:21171297 RGD:5128559 RGD:7829804 RGD:7829817 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL5 interleukin 5 ISO protein: increased levels: sputum RGD PMID:22186238 RGD:5687140 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212 		JBrowse link
G LOC100739508 glutathione S-transferase P-like susceptibility ISO DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:17181111 RGD:4142523 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased expression:nasal mucosa: RGD PMID:19786210 RGD:5130872 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:nasal mucosa: RGD PMID:19786210 RGD:5130872 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:nasal mucosa RGD PMID:14587983 RGD:4892078 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO DNA:snp:promoter:g.-786T>C (human) RGD PMID:18086269 RGD:4892054 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO protein:altered expression:nasal mucosa RGD PMID:20185258 RGD:4892593 NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,939...144,956,451 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO mRNA, protein:increased expression:nasal mucosa (human) RGD PMID:17116814 RGD:8552811 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:respiratory system epithelium RGD PMID:19364335 RGD:5147461 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G TBXA2R thromboxane A2 receptor treatment ISO RGD PMID:15247523 RGD:11059532 NCBI chr 2:75,068,413...75,081,305
Ensembl chr 2:75,068,698...75,087,731 		JBrowse link
Seasonal Allergic Rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:16677242 RGD:5147463 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094 		JBrowse link
G APOA4 apolipoprotein A4 resistance ISO protein:increased expression:blood serum (human) RGD PMID:20810159 RGD:5685642 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G BDNF brain derived neurotrophic factor severity ISO protein:increased expression:blood, nasal cavity epithelium RGD PMID:18266897 RGD:5144117 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:inferior turbinate, epithelium (human) RGD PMID:20459697 RGD:4891379 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118 		JBrowse link
G FGA fibrinogen alpha chain ISO RGD PMID:21887273 RGD:5688767 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO protein:decreased expression;T lymphocyte: RGD PMID:21410266 RGD:5491008 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased secretion:nasopharynx, secretion (human) RGD PMID:20128420 RGD:4145459 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 RGD:6480431 NCBI chr 1:27,037,151...27,061,095
Ensembl chr 1:27,037,165...27,061,093 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:19505388 RGD:7365025 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL18 interleukin 18 susceptibility
no_association		 ISO DNA:SNPs:promoters, exon:multiple
DNA:SNPs:promoters:multiple		 RGD PMID:12532106 RGD:8655871 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL4 interleukin 4 ISO protein:increased expression:serum
mRNA:increased expression:nose:		 RGD PMID:7551298 PMID:9237816 RGD:7829817 RGD:8662960 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 RGD:8551771 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336 		JBrowse link
G MC1R melanocortin 1 receptor no_association ISO RGD PMID:20357480 RGD:5687317 NCBI chr 6:181,225...182,187
Ensembl chr 6:181,225...182,187 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO DNA:SNPs:promoter, intron, cds:-1590C>T, 2127G>T, p.R668Q (rs3918242, rs2274755, rs17577) (human) RGD PMID:22237587 RGD:8547819 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human) RGD PMID:16918516 RGD:5131519 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,264 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:5'UTR/exon, exon:rs5743266, rs2066842 (human) RGD PMID:16008671 RGD:5131477 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:respiratory system epithelium RGD PMID:19364335 RGD:5147461 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA, protein:decreased expression:nasal lavage fluid RGD PMID:15836756 RGD:5144234 NCBI chr 2:9,297,282...9,302,204
Ensembl chr 2:9,297,283...9,302,165 		JBrowse link
G TLR3 toll like receptor 3 ISO protein:decreased expression:bone marrow, blood, eosinophil (human) RGD PMID:19752565 RGD:5129130 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291 		JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:polymorphisms:cds:p.D299G, T399I (human) RGD PMID:18517079 RGD:4144192 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO mRNA,protein:increased expression:nasal biopsies,nasal lavage fluid: RGD PMID:12633568 RGD:7483595 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    disease of anatomical entity 14873
      respiratory system disease 3345
        respiratory allergy 367
          allergic rhinitis 79
            Allergic Rhinoconjunctivitis 1
            Perennial Allergic Rhinitis 32
            Seasonal Allergic Rhinitis + 21
Path 2
Term Annotations click to browse term
  disease 17412
    Pathological Conditions, Signs and Symptoms 11799
      Signs and Symptoms 9738
        Neurologic Manifestations 9418
          sensory system disease 6507
            Otorhinolaryngologic Diseases 1660
              nose disease 216
                nasal cavity disease 178
                  rhinitis 146
                    allergic rhinitis 79
                      Allergic Rhinoconjunctivitis 1
                      Perennial Allergic Rhinitis 32
                      Seasonal Allergic Rhinitis + 21
paths to the root