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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:renal carcinoma
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Accession:DOID:4451 term browser browse the term
Definition:A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products). (DO)
Synonyms:exact_synonym: carcinoma of kidney;   kidney carcinoma
 primary_id: RDO:9002264
 xref: NCI:C124802;   NCI:C9384
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
renal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOSL1 FOS like 1, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr 2:28,392,855...28,417,317
Ensembl chr 2:28,392,448...28,417,317
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
JBrowse link
G LETMD1 LETM1 domain containing 1 IEP mRNA, protein:increased expression:kidney RGD PMID:12879013 RGD:2314918 NCBI chr12:51,048,220...51,068,958
Ensembl chr12:51,047,962...51,060,424
JBrowse link
G MCPH1 microcephalin 1 IEP protein:decreased expression:kidney (human) RGD PMID:25197360 RGD:9589037 NCBI chr 8:6,406,615...6,648,508
Ensembl chr 8:6,406,596...6,648,508
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Kidney Carcinoma ClinVar PMID:9140397, PMID:9563489, PMID:9731534, PMID:9826708, PMID:10327054, PMID:11750879, PMID:17483355, PMID:18829470, PMID:23213094, PMID:23610116, PMID:24121490, PMID:25157968, PMID:28492532 NCBI chr 7:116,672,196...116,798,386
Ensembl chr 7:116,672,196...116,798,386
JBrowse link
G MTOR mechanistic target of rapamycin kinase IAGP ClinVar Annotator: match by term: Kidney Carcinoma
ClinVar Annotator: match by term: Renal carcinoma
ClinVar PMID:24622468, PMID:24631838, PMID:25741868, PMID:26018084, PMID:26619011, PMID:27159400, PMID:27830187 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Renal carcinoma ClinVar PMID:1654209, PMID:2278970, PMID:2674680, PMID:3122217, PMID:6587382, PMID:8120410, PMID:10821536, PMID:12460918, PMID:12727991, PMID:14508525, PMID:15899789, PMID:16273091, PMID:16291983, PMID:16434492, PMID:17699718, PMID:18390968, PMID:18633438, PMID:18668139, PMID:18948947, PMID:19075190, PMID:19657110, PMID:19880792, PMID:20130576, PMID:20149136, PMID:20179705, PMID:20406486, PMID:20619739, PMID:20736745, PMID:21107323, PMID:21305640, PMID:21576590, PMID:21729679, PMID:21829508, PMID:22407852, PMID:22499344, PMID:22718121, PMID:22761467, PMID:22773810, PMID:23076151, PMID:23392294, PMID:23400451, PMID:23414587, PMID:23515407, PMID:23538902, PMID:23569304, PMID:23614898, PMID:24006476, PMID:24033266, PMID:24148783, PMID:24370118, PMID:24671188, PMID:25157968, PMID:25348872, PMID:25695684, PMID:26619011, PMID:26821351, PMID:27050078, PMID:28492532, PMID:28780248 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Renal carcinoma ClinVar PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:21824802, PMID:22162582, PMID:22162589, PMID:22271473, PMID:22658544, PMID:22729222, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23100325, PMID:23408298, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24782230, PMID:25157968, PMID:25741868, PMID:26266975, PMID:26266985, PMID:26619011, PMID:26822237, PMID:27626068, PMID:27631024, PMID:28492532, PMID:29446767, PMID:31775759 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Renal carcinoma ClinVar PMID:9467011, PMID:9915974, PMID:10866302, PMID:11504908, PMID:11875759, PMID:16773562, PMID:17526801, PMID:17942903, PMID:18767981, PMID:19457929, PMID:20085938, PMID:20300775, PMID:21659347, PMID:21822720, PMID:21824802, PMID:21828076, PMID:22266152, PMID:22320991, PMID:22327138, PMID:22595938, PMID:23335809, PMID:23399955, PMID:23470840, PMID:24778394, PMID:25157968, PMID:25527629, PMID:25741868, PMID:26619011, PMID:26798346, PMID:27477328, PMID:27535533, PMID:28475857, PMID:28492532, PMID:29359449, PMID:29706350 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: Renal carcinoma ClinVar PMID:26619011 NCBI chr11:66,052,361...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Renal carcinoma ClinVar PMID:1349175, PMID:1565143, PMID:1565144, PMID:1644930, PMID:1737852, PMID:7651740, PMID:7707106, PMID:7732013, PMID:7887414, PMID:8023157, PMID:8080050, PMID:8118819, PMID:8401536, PMID:8633021, PMID:8718514, PMID:8829627, PMID:8869100, PMID:9096669, PMID:9242456, PMID:9290701, PMID:9546439, PMID:9572492, PMID:9635828, PMID:9662334, PMID:9667734, PMID:10064694, PMID:10366100, PMID:10432928, PMID:10589545, PMID:10753186, PMID:10761705, PMID:10864200, PMID:10922393, PMID:11370630, PMID:11429705, PMID:11782540, PMID:11793474, PMID:11896595, PMID:11920788, PMID:11920959, PMID:12826609, PMID:12909720, PMID:12917626, PMID:14584079, PMID:15037740, PMID:15161705, PMID:15850016, PMID:15925506, PMID:15977174, PMID:15982667, PMID:16312222, PMID:16494995, PMID:16508005, PMID:16736287, PMID:16818505, PMID:16861262, PMID:17015838, PMID:17390010, PMID:17401428, PMID:17541742, PMID:17572079, PMID:17606709, PMID:18208484, PMID:18307025, PMID:18453682, PMID:18511570, PMID:18555592, PMID:19012332, PMID:19101993, PMID:19147582, PMID:19171880, PMID:19336573, PMID:19468865, PMID:19556618, PMID:19681600, PMID:19850740, PMID:19913028, PMID:20028212, PMID:20118236, PMID:20127978, PMID:20128691, PMID:20234365, PMID:20407015, PMID:20505364, PMID:20506564, PMID:20522432, PMID:20805372, PMID:20972454, PMID:21059199, PMID:21159183, PMID:21232794, PMID:21305319, PMID:21319261, PMID:21343334, PMID:21356188, PMID:21519010, PMID:21626334, PMID:21674059, PMID:21761402, PMID:22090360, PMID:22186996, PMID:22672556, PMID:22710932, PMID:22844452, PMID:22887876, PMID:22915647, PMID:22923379, PMID:22983585, PMID:23031740, PMID:23161690, PMID:23165212, PMID:23175693, PMID:23246812, PMID:23259501, PMID:23315175, PMID:23630318, PMID:23894400, PMID:24033266, PMID:24256616, PMID:24381225, PMID:24384472, PMID:24395441, PMID:24487413, PMID:24573247, PMID:24641375, PMID:24702488, PMID:24728327, PMID:24766216, PMID:25293557, PMID:25503501, PMID:25584008, PMID:25584637, PMID:25619955, PMID:25741868, PMID:25787918, PMID:25896519, PMID:25952993, PMID:25980754, PMID:26014290, PMID:26022348, PMID:26230955, PMID:26270727, PMID:26467025, PMID:26554828, PMID:26556299, PMID:26585234, PMID:26619011, PMID:26659639, PMID:26787237, PMID:26845104, PMID:26878390, PMID:26911350, PMID:26976419, PMID:27022024, PMID:27077130, PMID:27189670, PMID:27276561, PMID:27463065, PMID:27493922, PMID:27533082, PMID:27616075, PMID:27622479, PMID:27680515, PMID:27895058, PMID:27959731, PMID:28135145, PMID:28279309, PMID:28369373, PMID:28472496, PMID:28492532, PMID:28802053, PMID:28861920, PMID:28915717, PMID:28975465, PMID:29070607, PMID:29126202, PMID:29324801, PMID:29489754, PMID:29753700, PMID:29979965, PMID:30128536, PMID:30216591, PMID:30224644, PMID:30297838, PMID:30306255, PMID:30311369, PMID:30327374, PMID:30352134, PMID:30450585, PMID:30720243, PMID:31775759 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
chromophobe renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A IAGP ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:9754819, PMID:15649945, PMID:19929997, PMID:21696527, PMID:22432108, PMID:25741868, PMID:28492532 NCBI chr12:120,977,683...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G HNF1B HNF1 homeobox B IAGP ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:15649945, PMID:16371430, PMID:25536396, PMID:25700310, PMID:25741868 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,105
JBrowse link
clear cell renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor IEP mRNA:increased expression:renal cortex (human) RGD PMID:21947243 RGD:7244181 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 IEP RGD PMID:28672194 RGD:14696810 NCBI chr12:53,665,166...53,677,546
Ensembl chr12:53,632,726...53,677,408
JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b IEP RGD PMID:28672194 RGD:14696810 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773
JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP IEP RGD PMID:28672194 RGD:14696810 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814
JBrowse link
G BAX BCL2 associated X, apoptosis regulator IEP mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G DNMT1 DNA methyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,345...10,231,286
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 disease_progression IEP RGD PMID:23788753 RGD:13506731 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
JBrowse link
G ENG endoglin severity IEP protein:increased expression:tumor, vasculature (human)
protein:decreased expression:kidney, tumor (human)
RGD PMID:22204709, PMID:16536758 RGD:7248775, RGD:7248780 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G EP300 E1A binding protein p300 severity IEP mRNA:altered expression:kidney, tumor (human)
mRNA, protein:increased expression:kidney
RGD PMID:23029358, PMID:28551630 RGD:7296925, RGD:15036804 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:brain RGD PMID:22065054 RGD:6893520 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr 5:180,601,506...180,650,298
Ensembl chr 5:180,601,506...180,649,624
JBrowse link
G GSTP1 glutathione S-transferase pi 1 IAGP RGD PMID:10383153 RGD:6906878 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G HNF1A HNF1 homeobox A IAGP ClinVar Annotator: match by term: Clear cell renal cell carcinoma
ClinVar Annotator: match by term: Clear cell carcinoma of kidney
ClinVar PMID:8866553, PMID:8945470, PMID:9032114, PMID:9045858, PMID:9075818, PMID:9166684, PMID:9313763, PMID:9392505, PMID:9439666, PMID:9754819, PMID:10333057, PMID:10447526, PMID:10754480, PMID:11058894, PMID:11315851, PMID:12050210, PMID:12355088, PMID:12530534, PMID:12574234, PMID:12618559, PMID:15649945, PMID:15928245, PMID:17054605, PMID:17407387, PMID:17440016, PMID:17573900, PMID:17937063, PMID:17989309, PMID:18414213, PMID:18672310, PMID:19929997, PMID:21051477, PMID:21628466, PMID:21696527, PMID:22432108, PMID:23551881, PMID:23607861, PMID:25174781, PMID:25741868, PMID:26467025, PMID:28492532 NCBI chr12:120,977,683...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G IGF1R insulin like growth factor 1 receptor IMP xenograph of human clear cell renal cancer cells in mouse RGD PMID:19509240 RGD:7242921 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G KAT8 lysine acetyltransferase 8 IEP mRNA, protein:decreased expression:kidney (human) RGD PMID:23394073 RGD:9586034 NCBI chr16:31,117,664...31,131,393
Ensembl chr16:31,114,489...31,131,393
JBrowse link
G MMP12 matrix metallopeptidase 12 IEP RGD PMID:11576837 RGD:2290421 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
severity
IAGP DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) RGD PMID:21489764, PMID:20039875 RGD:6893474, RGD:6893632 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity IEP protein:increased expression:kidney (human) RGD PMID:21881486 RGD:7207420 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase IAGP ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:10987279 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 disease_progression IEP RGD PMID:25744653 RGD:13504816 NCBI chr19:39,125,786...39,182,816
Ensembl chr19:39,125,770...39,182,816
JBrowse link
G PAK6 p21 (RAC1) activated kinase 6 disease_progression IDA RGD PMID:24715215 RGD:13506722 NCBI chr15:40,239,063...40,277,487
Ensembl chr15:40,217,428...40,277,487
JBrowse link
G PBRM1 polybromo 1 IAGP ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:25911086 NCBI chr 3:52,545,367...52,685,913
Ensembl chr 3:52,545,352...52,685,917
JBrowse link
G PDGFB platelet derived growth factor subunit B disease_progression IEP
IDA
RGD PMID:25766258, PMID:23879920 RGD:13504817, RGD:13506650 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 IEP mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr17:58,000,919...58,007,273
Ensembl chr17:58,000,919...58,007,346
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 IEP mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,374
Ensembl chr17:76,734,115...76,737,374
JBrowse link
G SRSF4 serine and arginine rich splicing factor 4 IEP mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 1:29,147,743...29,181,900
Ensembl chr 1:29,147,743...29,181,900
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 IEP mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr14:69,767,112...69,772,005
Ensembl chr14:69,726,900...69,772,005
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 IEP mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr20:43,457,893...43,464,243
Ensembl chr20:43,457,893...43,466,046
JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 IEP mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 2:38,743,599...38,751,494
Ensembl chr 2:38,743,599...38,751,494
JBrowse link
G TP53 tumor protein p53 IEP mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
hereditary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE1 deoxyribonuclease 1 IAGP ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr16:3,611,737...3,665,472
Ensembl chr16:3,611,728...3,680,143
JBrowse link
G EGF epidermal growth factor IAGP ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 IAGP ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A IAGP ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar PMID:28492532, PMID:28546994 NCBI chr 5:218,309...264,816
Ensembl chr 5:218,241...257,082
JBrowse link
G TRAP1 TNF receptor associated protein 1 IAGP ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553
JBrowse link
nonpapillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK1 calcium/calmodulin dependent protein kinase I IAGP ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary ClinVar NCBI chr 3:9,757,345...9,769,987
Ensembl chr 3:9,757,347...9,769,992
JBrowse link
G FLCN folliculin IEA
IAGP
ISS
OMIM:144700
ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary
MouseDO
ClinVar
PMID:15805188, PMID:15852235, PMID:18234728, PMID:19457309, PMID:19802896, PMID:20618353, PMID:21937013, PMID:23050938, PMID:24393238, PMID:24728327, PMID:25594584, PMID:25741868, PMID:28492532, PMID:28558743 NCBI chr17:17,206,946...17,237,188
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G HNF1A HNF1 homeobox A IEA OMIM:144700 MouseDO NCBI chr12:120,977,683...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G HNF1B HNF1 homeobox B IEA OMIM:144700 MouseDO NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,105
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase IAGP
IEA
ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary
OMIM:144700
ClinVar
MouseDO
NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G RNF139 ring finger protein 139 IEA OMIM:144700 MouseDO NCBI chr 8:124,474,880...124,488,618
Ensembl chr 8:124,474,738...124,487,914
Ensembl chr 8:124,474,738...124,487,914
JBrowse link
G VHL von Hippel-Lindau tumor suppressor IEA OMIM:144700 MouseDO NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,008...10,152,220
Ensembl chr 3:10,141,008...10,152,220
JBrowse link
papillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma ClinVar PMID:25741868, PMID:28492532 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G ARAF A-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458, PMID:26619011 NCBI chr  X:47,561,205...47,571,908
Ensembl chr  X:47,561,100...47,571,920
JBrowse link
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,363,222...117,427,493
Ensembl chr 7:117,363,222...117,428,123
JBrowse link
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:10571946 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:12068308, PMID:12198537, PMID:12447372, PMID:12460918, PMID:12460919, PMID:12619120, PMID:12644542, PMID:12670889, PMID:12794760, PMID:12960123, PMID:14513361, PMID:14602780, PMID:14679157, PMID:15001635, PMID:15035987, PMID:15126572, PMID:15181070, PMID:15342696, PMID:15356022, PMID:15386408, PMID:15687339, PMID:15998781, PMID:16015629, PMID:16174717, PMID:16187918, PMID:16772349, PMID:17374713, PMID:17488796, PMID:17785355, PMID:18398503, PMID:19001320, PMID:19010912, PMID:19018267, PMID:19238210, PMID:19404918, PMID:19537845, PMID:19561230, PMID:20008640, PMID:20350999, PMID:20413299, PMID:20619739, PMID:20630094, PMID:20818844, PMID:20823850, PMID:20857202, PMID:21107320, PMID:21107323, PMID:21129611, PMID:21156289, PMID:21163703, PMID:21426297, PMID:21483012, PMID:21502544, PMID:21639808, PMID:21641636, PMID:21683865, PMID:21975775, PMID:22038996, PMID:22048237, PMID:22113612, PMID:22180495, PMID:22281684, PMID:22351686, PMID:22356324, PMID:22389471, PMID:22448344, PMID:22536370, PMID:22586120, PMID:22608338, PMID:22649091, PMID:22663011, PMID:22735384, PMID:22743296, PMID:22773810, PMID:22805292, PMID:22972589, PMID:22997239, PMID:23020132, PMID:23031422, PMID:23251002, PMID:23302800, PMID:23325582, PMID:23470635, PMID:23524406, PMID:23549875, PMID:23614898, PMID:23685455, PMID:23812671, PMID:23833300, PMID:23845441, PMID:23918947, PMID:24033266, PMID:24107445, PMID:24112392, PMID:24163374, PMID:24388723, PMID:24446311, PMID:24508103, PMID:24512911, PMID:24576830, PMID:24583796, PMID:24586605, PMID:24594804, PMID:24670642, PMID:24717435, PMID:25024077, PMID:25037139, PMID:25079330, PMID:25157968, PMID:25265492, PMID:25265494, PMID:25370471, PMID:25399551, PMID:25950823, PMID:25989278, PMID:26619011, PMID:26678033, PMID:27404270, PMID:27480103, PMID:28854169, PMID:28891408, PMID:29925953, PMID:31779674, PMID:31891627 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,862,587...116,922,049
Ensembl chr 7:116,811,070...116,922,049
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:25741868, PMID:26619011 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CFTR CF transmembrane conductance regulator IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G COMETT cytosolic oncogenic antisense to MET transcript IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar NCBI chr 7:116,563,594...116,688,027
Ensembl chr 7:116,563,594...116,663,829
JBrowse link
G CTNNB1 catenin beta 1 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26822237 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G ELOC elongin C IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 8:73,945,119...73,972,287
Ensembl chr 8:73,939,169...73,972,287
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839, PMID:22046346, PMID:23220880, PMID:25157968, PMID:26619011 NCBI chr17:39,688,094...39,728,660
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 4:152,320,544...152,536,873
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:8589699, PMID:8845844, PMID:9438390, PMID:9843049, PMID:10471491, PMID:11038465, PMID:11429702, PMID:11879084, PMID:15772091, PMID:17384684, PMID:19088846, PMID:19331127, PMID:19381019, PMID:19749790, PMID:20542753, PMID:21273588, PMID:22869148, PMID:23200862, PMID:24476948, PMID:25157968, PMID:25606676, PMID:25741868, PMID:26619011, PMID:28249712, PMID:28492532, PMID:30311386 NCBI chr 4:1,793,293...1,808,872
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:11150980, PMID:12210337, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17250658, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19371735, PMID:19382114, PMID:19669404, PMID:20660566, PMID:20979192, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22926243, PMID:23751039, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:25157968, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
JBrowse link
G LOC107303340 3p25 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Alu-mediated recombination region IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:7660122, PMID:7728151, PMID:7784063, PMID:7987306, PMID:7987327, PMID:8270255, PMID:8522307, PMID:8592333, PMID:8707293, PMID:8730290, PMID:8956040, PMID:9156047, PMID:9452032, PMID:9829911, PMID:9829912, PMID:10567493, PMID:10900011, PMID:11309459, PMID:11921283, PMID:12000816, PMID:12114495, PMID:14722919, PMID:14973063, PMID:14987375, PMID:15300849, PMID:15574766, PMID:17102069, PMID:17350623, PMID:18446368, PMID:18836774, PMID:19030229, PMID:19252526, PMID:19270817, PMID:19464396, PMID:19602254, PMID:20660572, PMID:21362373, PMID:21715564, PMID:22799452, PMID:23512077, PMID:24206762, PMID:24301059, PMID:25119015, PMID:25157968, PMID:25371412, PMID:25563310, PMID:25720320, PMID:25741868, PMID:25867206, PMID:26822237, PMID:27527340, PMID:27539324, PMID:27617348, PMID:28492532, PMID:28944243, PMID:29616089, PMID:30042107 NCBI chr 3:10,142,339...10,160,352 JBrowse link
G LOC111365177 HNF1 motif-containing MPRA enhancer 7 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,772,624...116,772,768 JBrowse link
G LOC111674463 CFTR promoter region IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,476,071...117,480,094 JBrowse link
G LOC111674464 CFTR intron 1 enhancer IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,489,455...117,492,403 JBrowse link
G LOC111674465 DNase I hypersensitive site -80 kb upstream of CFTR IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,399,495...117,400,694 JBrowse link
G LOC111674466 DNase I hypersensitive site -20.9 kb upstream of CFTR IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,458,800...117,459,399 JBrowse link
G LOC111674476 CFTR -35 kb upstream enhancer IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,444,395...117,445,995 JBrowse link
G LOC111674478 CFTR -44 kb upstream enhancer IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,434,807...117,436,695 JBrowse link
G LOC113219431 greater CFTR locus negative regulatory element CR5 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,704,761...116,705,488 JBrowse link
G LOC113219432 greater CFTR locus negative regulatory element CR8 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,764,110...116,764,598 JBrowse link
G LOC113219433 greater CFTR locus negative regulatory element CR10 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,159,028...117,159,408 JBrowse link
G LOC113219434 greater CFTR locus negative regulatory element NR4 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,088,745...117,089,385 JBrowse link
G LOC113219439 greater CFTR locus negative regulatory element CR6 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,734,066...116,734,517 JBrowse link
G LOC113219440 greater CFTR locus negative regulatory element CR11 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,190,018...117,190,413 JBrowse link
G LOC113219442 greater CFTR locus negative regulatory elements CR12 and CR13 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,286,203...117,286,743 JBrowse link
G LOC113219443 greater CFTR locus negative regulatory element CR15 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,315,946...117,316,585 JBrowse link
G LOC113219444 greater CFTR locus negative regulatory element CR9 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,918,230...116,918,944 JBrowse link
G LOC113219445 greater CFTR locus negative regulatory element CR17 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,324,329...117,324,786 JBrowse link
G LOC113219446 greater CFTR locus negative regulatory element CR18 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,364,729...117,364,917 JBrowse link
G LOC113219447 greater CFTR locus negative regulatory element NR9 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,473,966...117,474,605 JBrowse link
G LOC116186911 CRISPRi-validated cis-regulatory element chr7.4218 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,950,058...116,950,383 JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:11150980, PMID:12210337, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17250658, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19371735, PMID:19382114, PMID:19669404, PMID:20660566, PMID:20979192, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22926243, PMID:23751039, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:25157968, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759 NCBI chr11:518,967...554,916
Ensembl chr11:537,527...554,912
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar
OMIM
PMID:1104268, PMID:9140397, PMID:9326629, PMID:9563489, PMID:9731534, PMID:9826708, PMID:10327054, PMID:10417759, PMID:10433944, PMID:11042681, PMID:11354004, PMID:11750879, PMID:11927612, PMID:12920089, PMID:14559814, PMID:15371818, PMID:15592501, PMID:15735036, PMID:16189274, PMID:17088437, PMID:17483355, PMID:18564920, PMID:19318576, PMID:19723643, PMID:20126411, PMID:20139696, PMID:20670955, PMID:20949619, PMID:21904579, PMID:21970370, PMID:22703879, PMID:22717761, PMID:23213094, PMID:23806086, PMID:24033266, PMID:24061647, PMID:24088041, PMID:24121490, PMID:24658158, PMID:24728327, PMID:25157968, PMID:25605252, PMID:25636233, PMID:25637381, PMID:25736269, PMID:25741868, PMID:25859546, PMID:26173098, PMID:26467025, PMID:26700204, PMID:26718692, PMID:26887047, PMID:27153395, PMID:27666373, PMID:27696107, PMID:28294470, PMID:28476232, PMID:28492532, PMID:28603720, PMID:28619094 NCBI chr 7:116,672,196...116,798,386
Ensembl chr 7:116,672,196...116,798,386
JBrowse link
G MIR6132 microRNA 6132 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,020,211...117,020,319
Ensembl chr 7:117,020,211...117,020,319
JBrowse link
G MSH2 mutS homolog 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:18325052, PMID:21926548, PMID:24506336, PMID:24763289, PMID:25637381, PMID:25741868, PMID:26467025, PMID:26878173, PMID:26951660, PMID:28195393, PMID:28202063, PMID:28492532, PMID:28640387, PMID:29887214 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G MTOR mechanistic target of rapamycin kinase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:24631838, PMID:25741868, PMID:26018084, PMID:26619011, PMID:27159400, PMID:27830187 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:1654209, PMID:2278970, PMID:2674680, PMID:3122217, PMID:6587382, PMID:8120410, PMID:10821536, PMID:12460918, PMID:12727991, PMID:14508525, PMID:15899789, PMID:16273091, PMID:16291983, PMID:16434492, PMID:17699718, PMID:18390968, PMID:18633438, PMID:18668139, PMID:18948947, PMID:19075190, PMID:19657110, PMID:19880792, PMID:20130576, PMID:20149136, PMID:20179705, PMID:20406486, PMID:20619739, PMID:20736745, PMID:21107323, PMID:21305640, PMID:21576590, PMID:21729679, PMID:21829508, PMID:22407852, PMID:22499344, PMID:22718121, PMID:22761467, PMID:22773810, PMID:23076151, PMID:23392294, PMID:23400451, PMID:23414587, PMID:23515407, PMID:23538902, PMID:23569304, PMID:23614898, PMID:24006476, PMID:24033266, PMID:24148783, PMID:24370118, PMID:24671188, PMID:25157968, PMID:25348872, PMID:25695684, PMID:26619011, PMID:26821351, PMID:27050078, PMID:28492532, PMID:28780248 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:16847462, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:21824802, PMID:22162582, PMID:22162589, PMID:22228622, PMID:22271473, PMID:22357840, PMID:22658544, PMID:22729222, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23100325, PMID:23246288, PMID:23408298, PMID:23754335, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24497998, PMID:24559322, PMID:24782230, PMID:25157968, PMID:25557259, PMID:25741868, PMID:26266975, PMID:26266985, PMID:26301495, PMID:26593112, PMID:26619011, PMID:26822237, PMID:26851524, PMID:27426476, PMID:27626068, PMID:27631024, PMID:27870750, PMID:28492532, PMID:28941273, PMID:29446767, PMID:31775759 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PRCC proline rich mitotic checkpoint control factor IAGP OMIM NCBI chr 1:156,767,535...156,800,819
Ensembl chr 1:156,750,610...156,800,815
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:9467011, PMID:9915974, PMID:10866302, PMID:11504908, PMID:11875759, PMID:16773562, PMID:17526801, PMID:17942903, PMID:18767981, PMID:19457929, PMID:20085938, PMID:20300775, PMID:21659347, PMID:21822720, PMID:21824802, PMID:21828076, PMID:22266152, PMID:22320991, PMID:22327138, PMID:22595938, PMID:23335809, PMID:23399955, PMID:23470840, PMID:24778394, PMID:25157968, PMID:25527629, PMID:25741868, PMID:26619011, PMID:26798346, PMID:27477328, PMID:27535533, PMID:28475857, PMID:28492532, PMID:29359449, PMID:29706350 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G RHEB Ras homolog, mTORC1 binding IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120
JBrowse link
G RNU2-1 RNA, U2 small nuclear 1 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr17:43,233,790...43,233,977
Ensembl chr17:43,233,787...43,233,977
JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:18728283, PMID:19184535, PMID:19576851, PMID:22835832, PMID:24055113, PMID:24092654, PMID:25637381, PMID:25741868, PMID:26332594, PMID:28492532 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,722...17,054,032
JBrowse link
G SF3B1 splicing factor 3b subunit 1 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,091
Ensembl chr 2:197,388,515...197,435,091
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr11:66,052,361...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G ST7 suppression of tumorigenicity 7 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,953,501...117,230,176
Ensembl chr 7:116,953,238...117,230,103
JBrowse link
G ST7-AS1 ST7 antisense RNA 1 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,952,446...116,954,334
Ensembl chr 7:116,952,446...116,954,334
JBrowse link
G ST7-AS2 ST7 antisense RNA 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,072,072...117,145,592
Ensembl chr 7:117,072,072...117,146,480
JBrowse link
G ST7-OT3 ST7 overlapping transcript 3 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,182,681...117,209,937
Ensembl chr 7:116,953,238...117,230,103
JBrowse link
G ST7-OT4 ST7 overlapping transcript 4 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:116,953,848...116,959,817
Ensembl chr 7:116,953,899...117,098,806
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:1349175, PMID:1565143, PMID:1565144, PMID:1644930, PMID:1737852, PMID:7651740, PMID:7707106, PMID:7732013, PMID:7887414, PMID:8023157, PMID:8080050, PMID:8118819, PMID:8242631, PMID:8401536, PMID:8633021, PMID:8718514, PMID:8829627, PMID:8869100, PMID:9096669, PMID:9242456, PMID:9290701, PMID:9546439, PMID:9572492, PMID:9627118, PMID:9635828, PMID:9662334, PMID:9667734, PMID:10064694, PMID:10366100, PMID:10432928, PMID:10589545, PMID:10753186, PMID:10761705, PMID:10864200, PMID:10922393, PMID:11370630, PMID:11429705, PMID:11782540, PMID:11793474, PMID:11896595, PMID:11920788, PMID:11920959, PMID:12826609, PMID:12909720, PMID:12917626, PMID:14559903, PMID:14584079, PMID:15037740, PMID:15161705, PMID:15850016, PMID:15925506, PMID:15977174, PMID:15982667, PMID:16312222, PMID:16494995, PMID:16508005, PMID:16736287, PMID:16818505, PMID:16861262, PMID:17015838, PMID:17390010, PMID:17401428, PMID:17541742, PMID:17572079, PMID:17606709, PMID:18208484, PMID:18307025, PMID:18453682, PMID:18511570, PMID:18555592, PMID:19012332, PMID:19101993, PMID:19147582, PMID:19171880, PMID:19336573, PMID:19468865, PMID:19556618, PMID:19681600, PMID:19850740, PMID:19913028, PMID:20028212, PMID:20118236, PMID:20127978, PMID:20128691, PMID:20234365, PMID:20308654, PMID:20407015, PMID:20505364, PMID:20506564, PMID:20522432, PMID:20805372, PMID:20972454, PMID:21056685, PMID:21059199, PMID:21159183, PMID:21232794, PMID:21305319, PMID:21319261, PMID:21343334, PMID:21356188, PMID:21483000, PMID:21514416, PMID:21519010, PMID:21626334, PMID:21674059, PMID:21761402, PMID:22090360, PMID:22186996, PMID:22265402, PMID:22672556, PMID:22710932, PMID:22844452, PMID:22887876, PMID:22915647, PMID:22923379, PMID:22983585, PMID:23031740, PMID:23161690, PMID:23165212, PMID:23175693, PMID:23246812, PMID:23259501, PMID:23315175, PMID:23630318, PMID:23894400, PMID:24033266, PMID:24256616, PMID:24381225, PMID:24384472, PMID:24395441, PMID:24487413, PMID:24573247, PMID:24641375, PMID:24702488, PMID:24728327, PMID:24766216, PMID:25293557, PMID:25503501, PMID:25584008, PMID:25584637, PMID:25619955, PMID:25741868, PMID:25787918, PMID:25896519, PMID:25945745, PMID:25952993, PMID:25980754, PMID:26014290, PMID:26022348, PMID:26230955, PMID:26270727, PMID:26425688, PMID:26467025, PMID:26554828, PMID:26556299, PMID:26585234, PMID:26619011, PMID:26659639, PMID:26787237, PMID:26845104, PMID:26878390, PMID:26911350, PMID:26976419, PMID:27022024, PMID:27077130, PMID:27189670, PMID:27276561, PMID:27463065, PMID:27493922, PMID:27533082, PMID:27616075, PMID:27622479, PMID:27680515, PMID:27895058, PMID:27959731, PMID:28135145, PMID:28279309, PMID:28369373, PMID:28472496, PMID:28476805, PMID:28492532, PMID:28724667, PMID:28802053, PMID:28861920, PMID:28915717, PMID:28975465, PMID:29070607, PMID:29126202, PMID:29324801, PMID:29489754, PMID:29753700, PMID:29979965, PMID:30128536, PMID:30216591, PMID:30224644, PMID:30297838, PMID:30306255, PMID:30311369, PMID:30327374, PMID:30352134, PMID:30450585, PMID:30720243, PMID:31775759 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G VHL von Hippel-Lindau tumor suppressor IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:7660122, PMID:7728151, PMID:7784063, PMID:7987306, PMID:7987327, PMID:8270255, PMID:8522307, PMID:8592333, PMID:8707293, PMID:8730290, PMID:8956040, PMID:9156047, PMID:9452032, PMID:9829911, PMID:9829912, PMID:10567493, PMID:10900011, PMID:11309459, PMID:11921283, PMID:12000816, PMID:12114495, PMID:14722919, PMID:14973063, PMID:14987375, PMID:15300849, PMID:15574766, PMID:17102069, PMID:17350623, PMID:18446368, PMID:18836774, PMID:19030229, PMID:19252526, PMID:19270817, PMID:19464396, PMID:19602254, PMID:20660572, PMID:21362373, PMID:21715564, PMID:22799452, PMID:23512077, PMID:24206762, PMID:24301059, PMID:25119015, PMID:25157968, PMID:25371412, PMID:25563310, PMID:25720320, PMID:25741868, PMID:25867206, PMID:26822237, PMID:27527340, PMID:27539324, PMID:27617348, PMID:28492532, PMID:28944243, PMID:29616089, PMID:30042107 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,008...10,152,220
Ensembl chr 3:10,141,008...10,152,220
JBrowse link
G WNT2 Wnt family member 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:117,275,451...117,323,058
Ensembl chr 7:117,275,451...117,323,152
JBrowse link
renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 disease_progression IEP
IAGP
DNA:polymorphism: :3435C>T (human) RGD PMID:17177989, PMID:12089380 RGD:2315557, RGD:2315559 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) susceptibility IAGP DNA:polymorphism: :p.Q141K (human) RGD PMID:15906349 RGD:2315569 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACY1 aminoacylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 3:51,983,535...51,989,197
Ensembl chr 3:51,983,340...51,989,197
JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 severity IEP RGD PMID:21511296 RGD:13831349 NCBI chr 8:142,449,649...142,545,009
Ensembl chr 8:142,449,430...142,545,009
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:29723618 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G AFP alpha fetoprotein IEP RGD PMID:1714107 RGD:2292042 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AGTR1 angiotensin II receptor type 1 severity IEP protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr 3:148,697,871...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AGTR2 angiotensin II receptor type 2 disease_progression IEP protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G AHNAK AHNAK nucleoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
JBrowse link
G AKAP13 A-kinase anchoring protein 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEP protein:increased serine phosphorylation:kidney RGD PMID:17681738 RGD:1643331 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G AKT3 AKT serine/threonine kinase 3 susceptibility IAGP DNA:missense mutation:exon, intron:multiple RGD PMID:23378641 RGD:13503319 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079
JBrowse link
G ALAD aminolevulinate dehydratase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21799727 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALK ALK receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22743654 NCBI chr 2:29,190,992...29,921,589
Ensembl chr 2:29,192,774...29,921,586
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type IEP protein:increased expression:kidney RGD PMID:14654968 RGD:2315610 NCBI chr17:6,993,791...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type EXP CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:45,374,209...45,446,121
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G AMACR alpha-methylacyl-CoA racemase IEP RGD PMID:14707866 RGD:2315633 NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104
JBrowse link
G ANG angiogenin IEP protein:increased expression:serum RGD PMID:18808740 RGD:2325699 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G ANGPT1 angiopoietin 1 severity IEP mRNA:altered expression:kidney RGD PMID:17505508 RGD:1643335 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:14587099 RGD:7421570 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ANXA2 annexin A2 ISO RGD PMID:14587099 RGD:7421570 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G ANXA4 annexin A4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
JBrowse link
G AP5M1 adaptor related protein complex 5 subunit mu 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr14:57,268,915...57,298,742
Ensembl chr14:57,268,924...57,298,742
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
JBrowse link
G APC APC regulator of WNT signaling pathway onset
disease_progression
severity
ISO
IAGP
DNA,protein:LOH,decreased expression: :
DNA:LOH: :
RGD PMID:16116480, PMID:10426194, PMID:15203750 RGD:7242056, RGD:7242060, RGD:7242059 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G APRT adenine phosphoribosyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator treatment IAGP DNA:missense mutation: :pF446L (human) RGD PMID:27595394 RGD:13503335 NCBI chr 1:150,809,713...150,876,737
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G ASB15 ankyrin repeat and SOCS box containing 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 7:123,567,003...123,639,481
Ensembl chr 7:123,567,010...123,639,481
JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 IDA DNA:hypermethylation:promoter RGD PMID:21132003 RGD:14696812 NCBI chr12:53,665,166...53,677,546
Ensembl chr12:53,632,726...53,677,408
JBrowse link
G AURKA aurora kinase A IEP mRNA, protein:increased expression:kidney RGD PMID:17349527 RGD:1643346 NCBI chr20:56,369,390...56,392,308
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G BAD BCL2 associated agonist of cell death IEP RGD PMID:15851405 RGD:2292677 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAK1 BCL2 antagonist/killer 1 severity IEP RGD PMID:9894249 RGD:2315703 NCBI chr 6:33,572,552...33,580,296
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAP1 BRCA1 associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691, PMID:22683710, PMID:23797736, PMID:25231345 NCBI chr 3:52,401,004...52,410,030
Ensembl chr 3:52,401,008...52,410,008
JBrowse link
G BCHE butyrylcholinesterase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL2 BCL2 apoptosis regulator disease_progression IEP
IMP
RGD PMID:17482919, PMID:18283311 RGD:2293019, RGD:2298896 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 IEP RGD PMID:12025227 RGD:1643483 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BIK BCL2 interacting killer IEP protein:decreased expression:kidney RGD PMID:16322756 RGD:14394818 NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,750...43,129,712
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 disease_progression IEP mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr11:102,347,182...102,378,670
Ensembl chr11:102,347,211...102,378,670
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 IEP mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression IEP
EXP
mRNA:splice variant
CTD Direct Evidence: therapeutic
protein:increased expression:kidney
CTD PMID:16188142, PMID:12115583, PMID:17363528 RGD:2293108, RGD:2293102 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17437058, PMID:25401301 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495
JBrowse link
G BMP4 bone morphogenetic protein 4 severity IEP RGD PMID:17644140 RGD:1643589 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMP6 bone morphogenetic protein 6 IEP mRNA,protein:increased expression:kidney RGD PMID:20016212 RGD:7242419 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BMP7 bone morphogenetic protein 7 disease_progression IEP RGD PMID:17644140 RGD:1643589 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G BSG basigin (Ok blood group) disease_progression IEP protein:increased expression:kidney RGD PMID:17021824 RGD:2289052 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,493
JBrowse link
G BTG2 BTG anti-proliferation factor 2 IEP mRNA:decreased expression:kidney RGD PMID:14996721 RGD:2289069 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G BTG3 BTG anti-proliferation factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19221000 NCBI chr21:17,593,653...17,612,940
Ensembl chr21:17,593,653...17,612,947
Ensembl chr21:17,593,653...17,612,947
JBrowse link
G C4A complement C4A (Rodgers blood group) disease_progression IAGP RGD PMID:19150565 RGD:5688259 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681
JBrowse link
G C4B complement C4B (Chido blood group) disease_progression IAGP RGD PMID:19150565 RGD:5688259 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
JBrowse link
G CA9 carbonic anhydrase 9 disease_progression IDA
IEP
DNA, mRNA:hypomethylation, increased expression:promoter, kidney
protein:increased expression:serum, urine
RGD PMID:11506497, PMID:12966427, PMID:12883698, PMID:18464292 RGD:2293201, RGD:2293198, RGD:2293199, RGD:2293191 NCBI chr 9:35,673,809...35,681,159
Ensembl chr 9:35,673,918...35,681,159
JBrowse link
G CAPG capping actin protein, gelsolin like EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 2:85,394,753...85,418,467
Ensembl chr 2:85,394,753...85,418,432
JBrowse link
G CARD11 caspase recruitment domain family member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,141...3,043,945
JBrowse link
G CASP2 caspase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
JBrowse link
G CASP3 caspase 3 IEP RGD PMID:17513560 RGD:2293308 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CAV1 caveolin 1 disease_progression IEP protein:increased expression:kidney RGD PMID:15247769 RGD:2289107 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CCNB1 cyclin B1 disease_progression IEP protein:increased expression:kidney RGD PMID:16557593 RGD:2315941 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CCND1 cyclin D1 IAGP
IEP
DNA:polymorphism RGD PMID:15538282, PMID:17924468 RGD:2289130, RGD:2289127 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND3 cyclin D3 disease_progression IEP RGD PMID:18679818 RGD:2316007 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCNE1 cyclin E1 IEP mRNA, protein:increased expression:kidney RGD PMID:17726548 RGD:2289228 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:15282531, PMID:12594303, PMID:20426873 RGD:7248440, RGD:11522744, RGD:7248724 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CD44 CD44 molecule (Indian blood group) disease_progression
severity
IEP protein:increased expression:kidney RGD PMID:12833185, PMID:17284111 RGD:2289360, RGD:2289351 NCBI chr11:35,139,168...35,232,402
Ensembl chr11:35,138,882...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD46 CD46 molecule IEP protein:decreased expression:tumor:expression associated with presence of complement C3d on tumor cells (p<0.02) and with tumor stage (p<0.04) RGD PMID:10744069 RGD:2293550 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,057...207,795,513
Ensembl chr 1:207,752,057...207,795,513
JBrowse link
G CDC14B cell division cycle 14B severity IEP mRNA:decreased expression:kidney: RGD PMID:24619757 RGD:10059341 NCBI chr 9:96,492,743...96,619,843
Ensembl chr 9:96,490,241...96,619,843
JBrowse link
G CDH1 cadherin 1 disease_progression
onset
IDA
IAGP
protein:decreased expression, altered localization:kidney, nucleus
DNA:LOH: :
RGD PMID:17906660, PMID:15203750 RGD:2289489, RGD:7242059 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,541
JBrowse link
G CDK2 cyclin dependent kinase 2 IMP RGD PMID:16740772 RGD:2293561 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK4 cyclin dependent kinase 4 IEP protein:increased expression:kidney RGD PMID:15991006 RGD:2293579 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B disease_progression IEP protein:decreased expression:kidney
mRNA, protein:increased expression:kidney
RGD PMID:17924468, PMID:18425369, PMID:18495610 RGD:2289127, RGD:2293590, RGD:2293589 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,715,058...12,722,369
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO
IDA
DNA:gene instability
DNA, protein:hypermethylation, increased expression:promoter, kidney
DNA:deletion
RGD PMID:11839561, PMID:15232742, PMID:17201148 RGD:1298747, RGD:2289699, RGD:2289680 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO DNA:loss of heterozygosity, deletion RGD PMID:10391689 RGD:7248758 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CNN2 calponin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr19:1,026,608...1,039,065
Ensembl chr19:1,026,586...1,039,068
JBrowse link
G COMT catechol-O-methyltransferase susceptibility IAGP DNA:polymorphism:exon RGD PMID:17220335 RGD:2289716 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,733...19,969,975
Ensembl chr22:19,941,733...19,969,975
JBrowse link
G CPQ carboxypeptidase Q EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16254461 NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225
JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain EXP CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr12:93,677,342...93,894,840
Ensembl chr12:93,677,375...93,894,840
JBrowse link
G CRP C-reactive protein disease_progression IEP RGD PMID:22958305 RGD:6904212 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CRYAB crystallin alpha B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CSF1R colony stimulating factor 1 receptor IEP
IMP
mRNA:increased expression:kidney RGD PMID:18592004, PMID:22052465 RGD:2299092, RGD:7257566 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSMD3 CUB and Sushi multiple domains 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691, PMID:23797736 NCBI chr 8:112,222,928...113,437,499
Ensembl chr 8:112,222,928...113,436,939
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP DNA:SNPs:exons:rs3087243, rs231775 (human) RGD PMID:17678726 RGD:7204723 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G CTNNA1 catenin alpha 1 disease_progression IEP protein:decreased expression:kidney RGD PMID:9355975 RGD:2289799 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CTNNB1 catenin beta 1 disease_progression IEP protein:increased expression:kidney RGD PMID:15330191, PMID:11831984 RGD:2289794, RGD:2289835 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTSB cathepsin B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,448
JBrowse link
G CTSD cathepsin D EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CUL7 cullin 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 6:43,037,617...43,053,945
Ensembl chr 6:43,037,617...43,053,945
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:16210641 RGD:7257682 NCBI chr 2:218,125,294...218,137,253
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association IAGP
ISO
IEP
DNA:polymorphism: :p.I462V (human)
DNA:SNPs: :6235T>C, 4889A>G, 4887C>A (human)
RGD PMID:22296350, PMID:11115552, PMID:9631944, PMID:22000673 RGD:7257729, RGD:7296938, RGD:7296939, RGD:7296937 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G DAPK1 death associated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634
JBrowse link
G DNHD1 dynein heavy chain domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr11:6,497,280...6,572,020
Ensembl chr11:6,497,260...6,593,758
JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 disease_progression ISO RGD PMID:15867365 RGD:2289852 NCBI chr 8:109,539,702...109,565,996
Ensembl chr 8:109,539,711...109,565,996
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
JBrowse link
G EGFR epidermal growth factor receptor IEP protein:increased expression:tumor RGD PMID:18467719 RGD:2293730 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 IDA protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr 1:231,363,756...231,422,332
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EGLN2 egl-9 family hypoxia inducible factor 2 IDA protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr19:40,799,191...40,808,434
Ensembl chr19:40,798,996...40,808,434
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 IDA protein:increased expression:serum RGD PMID:20676679 RGD:13506732 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
JBrowse link
G ELOC elongin C EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 8:73,945,119...73,972,287
Ensembl chr 8:73,939,169...73,972,287
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:21131975, PMID:12750296 RGD:10395373 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEP
EXP
IDA
mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:10897039, PMID:15360049, PMID:17296437 RGD:2289987, RGD:2289930 NCBI chr17:39,688,094...39,728,660
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 IEP mRNA, protein:decreased expression:kidney RGD PMID:15360049 RGD:2289987 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G FAAH2 fatty acid amide hydrolase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr  X:57,121,861...57,489,196
Ensembl chr  X:57,286,706...57,489,196
JBrowse link
G FAM111B FAM111 trypsin like peptidase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr11:59,107,237...59,127,412
Ensembl chr11:59,107,185...59,127,412
JBrowse link
G FAS Fas cell surface death receptor ISO
IEP
IAGP
protein:increased expression:serum
DNA:missense mutations:exon
RGD PMID:11435457, PMID:10654915, PMID:17031406, PMID:12460460 RGD:2290132, RGD:2290133, RGD:2290099, RGD:2290131 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand ISO RGD PMID:11435457, PMID:17641033 RGD:2290132, RGD:2290051 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FGF2 fibroblast growth factor 2 disease_progression IEP protein:increased expression:serum RGD PMID:1718278 RGD:2290303 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 disease_progression IEP RGD PMID:25900027 RGD:11352663 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FH fumarate hydratase TAS RGD PMID:17211469 RGD:6907135 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,603...241,519,761
Ensembl chr 1:241,497,603...241,519,761
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase IEP
IAGP
protein:decreased expression::reduced or negative expression in 78% of clear cell RCCs
DNA:translocation::t(3;8)(p14;q24.1) results in disruption of FHIT and TRC8/RNF139 genes
RGD PMID:10530564, PMID:17539022 RGD:2289903, RGD:2289870 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459
JBrowse link
G FLCN folliculin treatment IAGP
ISO
EXP
ClinVar Annotator: match by term: HYPERNEPHROMA
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12204536, PMID:15805188, PMID:15852235, PMID:18234728, PMID:19457309, PMID:19802896, PMID:20618353, PMID:21937013, PMID:23050938, PMID:24393238, PMID:24728327, PMID:25594584, PMID:25741868, PMID:28492532, PMID:28558743, PMID:16369488, PMID:14769940 RGD:13605606, RGD:1302869 NCBI chr17:17,206,946...17,237,188
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IEP
EXP
protein:increased expression:kidney, blood, myeloid cell
CTD Direct Evidence: therapeutic
mRNA:increased expression:tumor:expression significantly higher in tumors than corresponding normal tissue (p=0.01), significantly correlated with VEGF expression
CTD PMID:16596207, PMID:18566400, PMID:11846206 RGD:2301250, RGD:2289960 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G FMN2 formin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:240,091,883...240,475,187
Ensembl chr 1:240,014,348...240,475,187
JBrowse link
G FN1 fibronectin 1 severity IEP RGD PMID:20860816 RGD:7205637 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FPGT fucose-1-phosphate guanylyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 1:74,198,242...74,208,702
Ensembl chr 1:74,198,212...74,234,086
JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 disease_progression IEP RGD PMID:25900027 RGD:11352663 NCBI chr12:69,470,371...69,579,793
Ensembl chr12:69,470,349...69,579,789
JBrowse link
G GHRH growth hormone releasing hormone IMP RGD PMID:10962030 RGD:2301426 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,082...37,261,835
JBrowse link
G GJB1 gap junction protein beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18264126 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G GRB7 growth factor receptor bound protein 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291
JBrowse link
G GSR glutathione-disulfide reductase IEP protein:decreased expression:kidney: RGD PMID:18312938 RGD:7257550 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:18566013, PMID:26656529, PMID:14504370 RGD:2293845 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 IEP
EXP
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:15108329, PMID:20464042 RGD:8547946 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:18566013, PMID:26656529, PMID:14504370 RGD:2293845
G HARS1 histidyl-tRNA synthetase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 5:140,673,905...140,691,370
Ensembl chr 5:140,673,035...140,691,537
Ensembl chr 5:140,673,035...140,691,537
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression IEP RGD PMID:23352434 RGD:7245470 NCBI chr 5:157,028,383...157,069,633
Ensembl chr 5:157,029,413...157,059,119
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 susceptibility IAGP DNA:polymorphisms: :-574G>T, +4259T>G (human) RGD PMID:22472081 RGD:7245505 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,832...157,142,869
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha disease_progression IEP RGD PMID:19302703 RGD:2306222 NCBI chr14:61,695,513...61,748,259
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility
disease_progression
IAGP RGD PMID:9044854, PMID:12771724, PMID:10895068 RGD:2314704, RGD:2314695, RGD:2314701 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HNF1A HNF1 homeobox A IAGP OMIM NCBI chr12:120,977,683...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G HNF1B HNF1 homeobox B IAGP OMIM NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,105
JBrowse link
G HOXB13 homeobox B13 disease_progression IDA DNA:hypermethylation RGD PMID:16278676 RGD:2314729 NCBI chr17:48,724,763...48,728,750
Ensembl chr17:48,724,763...48,729,178
Ensembl chr17:48,724,763...48,729,178
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:8886046 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:17952403 RGD:7242846 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 IEP mRNA,protein:increased expression:tumor:27/43 (63%) by cDNA microarray, 43/58 (74%) by immunohistochemistry RGD PMID:18076934 RGD:2290003 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO mRNA:decreased expression:kidney RGD PMID:10854235 RGD:1626565 NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385
JBrowse link
G IL13 interleukin 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22317767 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL1RN interleukin 1 receptor antagonist IDA RGD PMID:17031403 RGD:6907413 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL2 interleukin 2 IDA RGD PMID:21812652 RGD:5147871 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4R interleukin 4 receptor susceptibility
disease_progression
IAGP
EXP
DNA:polymorphism:cds:p.I50V (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:22317767, PMID:30472377, PMID:22317767, PMID:12171893 RGD:7207066, RGD:7207070 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 4:142,023,160...142,846,535
Ensembl chr 4:142,023,160...142,847,432
JBrowse link
G INSR insulin receptor IEP mRNA:increased expression:tumor:isoform A RGD PMID:15753986 RGD:2290462 NCBI chr19:7,112,257...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IEP protein:increased activation:tumor:associated with early carcinogenesis--10/18 (55.5%) of pT1a cases vs 11/44 (25%) of pT1b or greater cases RGD PMID:16006965 RGD:1549443 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G JUP junction plakoglobin IEP
IDA
protein:decreased expression:tumor:relative to normal kidney (p<0.001), higher expression associated with better survival rate (p<0.05)
DNA:increased methylation:promoter:significantly increased methylation vs normal kidney (p < 0.01)
RGD PMID:9891472, PMID:15701841 RGD:2291890, RGD:2291866 NCBI chr17:41,754,608...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 IEP DNA, mRNA, protein:hypermethylation, decreased expression:kidney RGD PMID:12133830 RGD:2315654 NCBI chr 9:470,295...746,104
Ensembl chr 9:470,291...746,106
JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 IEP protein:increased expression:kidney (human) RGD PMID:18777199 RGD:9693695 NCBI chr 1:210,678,314...211,134,148
Ensembl chr 1:210,676,823...211,134,165
JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:76,869,602...77,637,969
Ensembl chr10:76,869,601...77,638,369
JBrowse link
G KDM4C lysine demethylase 4C IAGP DNA:deletion:cds (human) RGD PMID:22483639 RGD:9587741 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648
JBrowse link
G KDM5C lysine demethylase 5C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,191,321...53,225,422
JBrowse link
G KDM6A lysine demethylase 6A TAS
IEP
mRNA, protein:increased expression:kidney (human) RGD PMID:21654818, PMID:23057811 RGD:6907137, RGD:9587837 NCBI chr  X:44,873,182...45,112,779
Ensembl chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KDM6B lysine demethylase 6B IEP mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr17:7,834,210...7,854,796
Ensembl chr17:7,839,904...7,854,796
JBrowse link
G KDR kinase insert domain receptor ISO RGD PMID:17653245, PMID:17332933 RGD:2301756, RGD:8552363 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KEAP1 kelch like ECH associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IAGP
IEP
papillary RCC only; DNA:mutation:intron:heterozygous T>A mutation in intron 17 found in 94% of cases, also protein found to be cytoplasmic not membrane-bound in 100% of cases
chromophobe RCC only; mRNA:increased expression:tumor:positive in 6/7 chromophobe RCCs, but 0/15 clear cell RCCs and 1/15 papillary RCCs
RGD PMID:15073597, PMID:15780567 RGD:2292421, RGD:2292414 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,918...54,740,715
JBrowse link
G KLK6 kallikrein related peptidase 6 IEP protein:decreased expression:kidney RGD PMID:16340244 RGD:2314864 NCBI chr19:50,958,631...50,969,598
Ensembl chr19:50,958,631...50,969,673
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IEP mRNA:increased expression:kidney RGD PMID:11851621 RGD:2314914 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G KRT32 keratin 32 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:41,459,513...41,469,252
Ensembl chr17:41,459,811...41,467,429
JBrowse link
G KRT7 keratin 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329, PMID:16927643 NCBI chr12:52,233,243...52,252,667
Ensembl chr12:52,232,520...52,252,186
JBrowse link
G KRT8 keratin 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G L1CAM L1 cell adhesion molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:21097529 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173
JBrowse link
G LDHB lactate dehydrogenase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr12:21,635,342...21,657,971
Ensembl chr12:21,635,342...21,757,857
JBrowse link
G LEP leptin resistance IEP RGD PMID:19278051 RGD:6907119 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LMAN2L lectin, mannose binding 2 like EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 2:96,705,929...96,740,072
Ensembl chr 2:96,705,929...96,740,064
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase IEP RGD PMID:17692401 RGD:2314919 NCBI chr 5:96,934,859...97,037,513
Ensembl chr 5:96,935,394...97,037,513
JBrowse link
G LOC107303340 3p25 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Alu-mediated recombination region IAGP ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis ClinVar PMID:11986208, PMID:15607616, PMID:19270817, PMID:28492532, PMID:29124493 NCBI chr 3:10,142,339...10,160,352 JBrowse link
G LRP1B LDL receptor related protein 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 2:140,231,423...142,132,463
Ensembl chr 2:140,231,423...142,131,016
Ensembl chr 2:140,231,423...142,131,016
JBrowse link
G LRRK2 leucine rich repeat kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr12:40,224,890...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G LTF lactotransferrin IDA RGD PMID:23201854 RGD:7243106 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
JBrowse link
G M6PR mannose-6-phosphate receptor, cation dependent EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr12:8,940,361...8,949,645
Ensembl chr12:8,940,361...8,949,761
JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor susceptibility IAGP RGD PMID:8649854 RGD:1599220 NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 IEP
IDA
protein:increased expression:tumor:13/25 cases (52%)
inhibition suppressed tumor growth and vascularization in an RCC xenograft model
RGD PMID:7664295, PMID:18172299 RGD:2292629, RGD:2292630 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,817...66,492,312
Ensembl chr15:66,386,817...66,492,312
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 susceptibility IAGP DNA:missense mutation: :multiple RGD PMID:22517515 RGD:13504815 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:25401301, PMID:9140397 RGD:1600122 NCBI chr 7:116,672,196...116,798,386
Ensembl chr 7:116,672,196...116,798,386
JBrowse link
G MGP matrix Gla protein disease_progression IEP mRNA:increased expression:tumor:inversely related to tumor size (0.025 RGD PMID:1399132 RGD:2293578 NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
JBrowse link
G MITF melanocyte inducing transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:22012259 NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,464...69,968,336
Ensembl chr 3:69,739,464...69,968,336
JBrowse link
G MLH1 mutL homolog 1 IEP protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr 3:36,993,487...37,050,846
Ensembl chr 3:36,993,350...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:21,524,616...21,743,630
Ensembl chr10:21,524,646...21,743,630
JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility
no_association
IAGP DNA:insertion:promoter:g.-1607insG (human) RGD PMID:12845675, PMID:17980059 RGD:7207023, RGD:7207082 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,919...102,798,160
JBrowse link
G MMP2 matrix metallopeptidase 2 disease_progression IEP protein:increased expression:kidney
mRNA:decreased expression:kidney
RGD PMID:17572184, PMID:18035688 RGD:2290359, RGD:2290358 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 IAGP DNA:missense mutation:cds:p.E45K rs679620 (human) RGD PMID:15319295, PMID:19551141 RGD:7207067, RGD:7241233 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP mRNA:increased expression:kidney RGD PMID:18035688 RGD:2290358 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MOK MOK protein kinase IEP mRNA:increased expression:kidney RGD PMID:15900605 RGD:7243170 NCBI chr14:102,224,441...102,305,191
Ensembl chr14:102,224,500...102,305,190
JBrowse link
G MSGN1 mesogenin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 2:17,816,460...17,817,798
Ensembl chr 2:17,816,460...17,817,798
JBrowse link
G MSH2 mutS homolog 2 IEP protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP DNA:missense mutation:cds:p.A222V (rs1801133) (human) RGD PMID:18098291 RGD:6893654 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTOR mechanistic target of rapamycin kinase IEP
IAGP
EXP
ClinVar Annotator: match by term: Renal cell cancer
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar
CTD
PMID:23797736, PMID:24631838, PMID:25741868, PMID:26018084, PMID:26619011, PMID:27159400, PMID:27830187, PMID:21881486 RGD:7207420 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MUC1 mucin 1, cell surface associated disease_progression IEP RGD PMID:10390012 RGD:7245968 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G MUC4 mucin 4, cell surface associated EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor IEP
ISO
mRNA:increased expression:kidney (human)
protein:increased expression:kidney (rat)
RGD PMID:21982273, PMID:18055543 RGD:7207793, RGD:7207841 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAV3 neuron navigator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr12:77,571,856...78,213,010
Ensembl chr12:77,324,641...78,213,010
JBrowse link
G NDRG1 N-myc downstream regulated 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022
Ensembl chr 8:133,237,175...133,302,022
JBrowse link
G NF2 neurofibromin 2 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:25401301, PMID:19487675 RGD:2315000 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598
JBrowse link
G NLRP12 NLR family pyrin domain containing 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr19:53,793,584...53,824,403
Ensembl chr19:53,793,603...53,824,394
Ensembl chr19:53,793,603...53,824,394
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 disease_progression IEP RGD PMID:9663430 RGD:2299059 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
Ensembl chr17:51,153,559...51,162,428
JBrowse link
G NNMT nicotinamide N-methyltransferase IEP mRNA:increased expression:kidney RGD PMID:17070307 RGD:2299120 NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536
Ensembl chr11:114,257,787...114,313,536
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 severity
treatment
IEP
IDA
RGD PMID:21531004, PMID:18181043 RGD:7174727, RGD:7174733 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma, somatic
ClinVar PMID:1654209, PMID:2278970, PMID:2674680, PMID:3122217, PMID:6587382, PMID:8120410, PMID:10821536, PMID:12460918, PMID:12727991, PMID:14508525, PMID:15899789, PMID:16273091, PMID:16291983, PMID:16434492, PMID:17699718, PMID:18390968, PMID:18633438, PMID:18668139, PMID:18948947, PMID:19075190, PMID:19657110, PMID:19880792, PMID:20130576, PMID:20149136, PMID:20179705, PMID:20406486, PMID:20619739, PMID:20736745, PMID:21107323, PMID:21305640, PMID:21576590, PMID:21729679, PMID:21829508, PMID:22407852, PMID:22499344, PMID:22718121, PMID:22761467, PMID:22773810, PMID:23076151, PMID:23392294, PMID:23400451, PMID:23414587, PMID:23515407, PMID:23538902, PMID:23569304, PMID:23614898, PMID:24006476, PMID:24033266, PMID:24148783, PMID:24370118, PMID:24671188, PMID:25157968, PMID:25348872, PMID:25695684, PMID:26619011, PMID:26821351, PMID:27050078, PMID:28492532, PMID:28780248 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO
IAGP
OMIM PMID:18218111, PMID:10987279 RGD:2317140, RGD:1600295 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G OR4C13 olfactory receptor family 4 subfamily C member 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr11:49,952,391...49,953,419
Ensembl chr11:49,952,391...49,953,419
JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 IEP
EXP
IMP
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:17621631, PMID:17621631, PMID:17621631 RGD:2299159, RGD:2299159 NCBI chr11:77,322,017...77,514,957
Ensembl chr11:77,321,707...77,474,635
Ensembl chr11:77,321,707...77,474,635
JBrowse link
G PBRM1 polybromo 1 TAS
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:22138691, PMID:23797736, PMID:21654818 RGD:6907137 NCBI chr 3:52,545,367...52,685,913
Ensembl chr 3:52,545,352...52,685,917
JBrowse link
G PCNA proliferating cell nuclear antigen severity IEP RGD PMID:11369057 RGD:2315008 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PDCD1 programmed cell death 1 disease_progression IEP RGD PMID:17363529 RGD:7248680 NCBI chr 2:241,849,881...241,858,908
Ensembl chr 2:241,849,884...241,858,894
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha disease_progression IEP protein:increased expression:kidney RGD PMID:12866380 RGD:2292157 NCBI chr 4:54,229,127...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
G PDGFRB platelet derived growth factor receptor beta IMP
IEP
mRNA:increased expression:kidney RGD PMID:15994946, PMID:16865223 RGD:2292198, RGD:2290496 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 3:58,427,630...58,433,832
Ensembl chr 3:58,427,630...58,433,857
JBrowse link
G PDPN podoplanin disease_progression IEP RGD PMID:18291512 RGD:2292239 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
JBrowse link
G PDXDC1 pyridoxal dependent decarboxylase domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr16:14,974,591...15,153,343
Ensembl chr16:14,974,591...15,139,339
JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25329396 NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584
JBrowse link
G PGF placental growth factor disease_progression IEP protein:increased expression:plasma RGD PMID:14981951 RGD:13506645 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G PGK1 phosphoglycerate kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295
JBrowse link
G PIDD1 p53-induced death domain protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr11:799,179...809,867
Ensembl chr11:799,179...809,753
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP
EXP
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal cell cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:21824802, PMID:22162582, PMID:22162589, PMID:22271473, PMID:22658544, PMID:22729222, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23100325, PMID:23408298, PMID:23797736, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24782230, PMID:25157968, PMID:25741868, PMID:26266975, PMID:26266985, PMID:26619011, PMID:26822237, PMID:27626068, PMID:27631024, PMID:28492532, PMID:29446767, PMID:31775759 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression IEP RGD PMID:25757764 RGD:13504823 NCBI chr 5:68,215,737...68,301,821
Ensembl chr 5:68,215,756...68,301,821
JBrowse link
G PLAU plasminogen activator, urokinase severity IEP mRNA:increased expression:kidney (human) RGD PMID:20544684 RGD:7241133 NCBI chr10:73,909,182...73,917,497
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLD2 phospholipase D2 IEP protein:increased expression:kidney RGD PMID:11185526 RGD:2299898 NCBI chr17:4,807,152...4,823,432
Ensembl chr17:4,807,152...4,823,434
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 IEP mRNA:increased expression:kidney RGD PMID:11568975 RGD:2315108 NCBI chr20:57,648,396...57,711,472
Ensembl chr20:57,648,392...57,711,536
JBrowse link
G PNKD PNKD metallo-beta-lactamase domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 2:218,270,485...218,346,793
Ensembl chr 2:218,270,392...218,346,793
JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: marker/mechanism CTD PMID:2844640 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:tumor (rat) RGD PMID:476627 RGD:5135050 NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:16179254 NCBI chr22:22,547,701...22,559,294
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PRCC proline rich mitotic checkpoint control factor EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 1:156,767,535...156,800,819
Ensembl chr 1:156,750,610...156,800,815
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 IAGP DNA:snp:promoter:g.-151G>T (human) RGD PMID:11788900 RGD:9999148 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
JBrowse link
G PTEN phosphatase and tensin homolog disease_progression IEP
IAGP
EXP
ISO
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma
CTD Direct Evidence: marker/mechanism
protein:decreased expression:kidney (rat)
ClinVar
CTD
PMID:9467011, PMID:9915974, PMID:10866302, PMID:11504908, PMID:11875759, PMID:16773562, PMID:17526801, PMID:17942903, PMID:18767981, PMID:19457929, PMID:20085938, PMID:20300775, PMID:21659347, PMID:21822720, PMID:21824802, PMID:21828076, PMID:22266152, PMID:22320991, PMID:22327138, PMID:22595938, PMID:23335809, PMID:23399955, PMID:23470840, PMID:24778394, PMID:25157968, PMID:25401301, PMID:25527629, PMID:25741868, PMID:26619011, PMID:26798346, PMID:27477328, PMID:27535533, PMID:28475857, PMID:28492532, PMID:29359449, PMID:29706350, PMID:15821467, PMID:22737271, PMID:17681738, PMID:17886097 RGD:2292513, RGD:12802360, RGD:1643331, RGD:2292500 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA:increased expression:kidney RGD PMID:12708469 RGD:2300212 NCBI chr 9:122,369,906...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression IEP
EXP
ISO
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:kidney
CTD PMID:12664575, PMID:17899436, PMID:12708469 RGD:2300204, RGD:2300212 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G PVALB parvalbumin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16927643 NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479
JBrowse link
G RASSF1 Ras association domain family member 1 IDA
TAS
DNA:hypermethylation:promoter RGD PMID:17645803, PMID:12222680 RGD:2299866, RGD:2291977 NCBI chr 3:50,329,786...50,340,836
Ensembl chr 3:50,329,782...50,340,980
JBrowse link
G RB1 RB transcriptional corepressor 1 disease_progression IEP RGD PMID:11549509 RGD:2299893 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IMP
EXP
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney
CTD PMID:18089796, PMID:17290398, PMID:12663495 RGD:2298755, RGD:2298771 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RNF139 ring finger protein 139 IAGP DNA:translocation::t(3;8)(p14;q24.1) results in disruption of FHIT and TRC8/RNF139 genes OMIM PMID:9689122, PMID:17539022 RGD:1599629, RGD:2289870 NCBI chr 8:124,474,880...124,488,618
Ensembl chr 8:124,474,738...124,487,914
Ensembl chr 8:124,474,738...124,487,914
JBrowse link
G RPL14 ribosomal protein L14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 3:40,457,339...40,468,587
Ensembl chr 3:40,457,292...40,468,587
JBrowse link
G RYR1 ryanodine receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,587,564
JBrowse link
G SCARB1 scavenger receptor class B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21131975 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B TAS RGD PMID:21771581 RGD:6907134 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,722...17,054,032
JBrowse link
G SDHD succinate dehydrogenase complex subunit D TAS RGD PMID:21771581 RGD:6907134 NCBI chr11:112,086,873...112,095,794
Ensembl chr11:112,086,824...112,120,016
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase TAS
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:22138691, PMID:23797736, PMID:21654818 RGD:6907137 NCBI chr 3:47,016,431...47,164,113
Ensembl chr 3:47,016,429...47,164,113
Ensembl chr 3:47,016,429...47,164,113
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:26619011 NCBI chr11:66,052,361...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G SFRP1 secreted frizzled related protein 1 IEP mRNA:decreased expression:kidney RGD PMID:20420713 RGD:4107084 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473
JBrowse link
G SFRP2 secreted frizzled related protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18404682 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
G SHANK1 SH3 and multiple ankyrin repeat domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr19:50,659,255...50,719,802
Ensembl chr19:50,661,827...50,719,450
JBrowse link
G SKP2 S-phase kinase associated protein 2 disease_progression IEP RGD PMID:18922157 RGD:2315038 NCBI chr 5:36,152,067...36,184,319
Ensembl chr 5:36,151,989...36,184,319
JBrowse link
G SLC2A1 solute carrier family 2 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7921415 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC49A4 solute carrier family 49 member 4 susceptibility IAGP DNA:translocation:intron:t(2;3)(q35;q21) RGD PMID:11912179 RGD:1601072 NCBI chr 3:122,795,058...122,892,157
Ensembl chr 3:122,795,069...122,881,139
JBrowse link
G SLC5A3 solute carrier family 5 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260
JBrowse link
G SMAD2 SMAD family member 2 severity IEP protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD4 SMAD family member 4 severity IEP protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPARC secreted protein acidic and cysteine rich IEP mRNA, protein:increased expression:kidney RGD PMID:11679940 RGD:2300025 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 disease_progression IEP protein:increased expression:serum
protein:decreased expression:kidney
RGD PMID:11176522, PMID:10508484 RGD:2300387, RGD:2300388 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,568...147,831,786
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr19:40,467,001...40,576,464
Ensembl chr19:40,466,241...40,576,464
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase IEP protein:increased expression:kidney RGD PMID:16501837 RGD:2315090 NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
JBrowse link
G STAT3 signal transducer and activator of transcription 3 disease_progression IEP
IAGP
protein:increased phosphorylation:kidney
DNA:snp
RGD PMID:12131365, PMID:17602083 RGD:2291917, RGD:2291913 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
JBrowse link
G SYNE2 spectrin repeat containing nuclear envelope protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr14:63,761,904...64,226,449
Ensembl chr14:63,761,899...64,226,433
Ensembl chr14:63,761,899...64,226,433
JBrowse link
G TAGLN2 transgelin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:159,918,111...159,925,507
Ensembl chr 1:159,918,107...159,925,732
Ensembl chr 1:159,918,107...159,925,732
JBrowse link
G TERC telomerase RNA component IEP RNA:decreased expression:kidney RGD PMID:11156238 RGD:2291972 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047
JBrowse link
G TERT telomerase reverse transcriptase IEP mRNA, protein:increased expression:kidney RGD PMID:18250061 RGD:2291980 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:12917640 RGD:1599384 NCBI chr  X:49,028,726...49,043,357
Ensembl chr  X:49,028,726...49,043,410
JBrowse link
G TFRC transferrin receptor IEP mRNA:decreased expression:kidney, T cell
protein:increased expression:kidney, T cell
RGD PMID:8050820, PMID:12394762 RGD:2292025, RGD:2292024 NCBI chr 3:196,018,694...196,082,123
Ensembl chr 3:196,027,183...196,082,096
JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression IEP
IDA
protein:increased expression:peripheral blood RGD PMID:26749573, PMID:25499257, PMID:26631499 RGD:11560966, RGD:13506175, RGD:13506173 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGM2 transglutaminase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr20:38,127,385...38,166,508
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G THRA thyroid hormone receptor alpha IAGP DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
JBrowse link
G THRB thyroid hormone receptor beta IAGP DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 disease_progression IEP protein:increased expression:kidney RGD PMID:11595703 RGD:2290350 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 disease_progression IEP protein:increased expression:kidney
mRNA:decreased expression:kidney
RGD PMID:17572184, PMID:18035688 RGD:2290359, RGD:2290358 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 IEP mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 IEP mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912
JBrowse link
G TLR9 toll like receptor 9 severity IEP protein:decreased expression:tumor, cytoplasm (human) RGD PMID:21929816 RGD:7246915 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,226,163
JBrowse link
G TNF tumor necrosis factor IMP
IEP
RGD PMID:19384924, PMID:19904265 RGD:2315119, RGD:2315113 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a IEP
IMP
mRNA:increased expression:kidney RGD PMID:16865223, PMID:17184908 RGD:2290496, RGD:2290491 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A IEP protein:increased expression:serum (human) RGD PMID:7912320 RGD:5131437 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B IEP RGD PMID:20566746 RGD:7245512 NCBI chr 1:12,166,948...12,209,222
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: therapeutic CTD PMID:20403343 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TP53 tumor protein p53 disease_progression IEP
IAGP
EXP
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Renal cell carcinoma, somatic
ClinVar
CTD
PMID:1349175, PMID:1565143, PMID:1565144, PMID:1644930, PMID:1737852, PMID:7651740, PMID:7707106, PMID:7732013, PMID:7887414, PMID:8023157, PMID:8080050, PMID:8118819, PMID:8401536, PMID:8633021, PMID:8718514, PMID:8829627, PMID:8869100, PMID:9096669, PMID:9242456, PMID:9290701, PMID:9546439, PMID:9572492, PMID:9635828, PMID:9662334, PMID:9667734, PMID:10064694, PMID:10366100, PMID:10432928, PMID:10589545, PMID:10753186, PMID:10761705, PMID:10864200, PMID:10922393, PMID:11370630, PMID:11429705, PMID:11782540, PMID:11793474, PMID:11896595, PMID:11920788, PMID:11920959, PMID:12826609, PMID:12909720, PMID:12917626, PMID:14584079, PMID:15037740, PMID:15161705, PMID:15850016, PMID:15925506, PMID:15977174, PMID:15982667, PMID:16312222, PMID:16494995, PMID:16508005, PMID:16736287, PMID:16818505, PMID:16861262, PMID:17015838, PMID:17275163, PMID:17390010, PMID:17401428, PMID:17541742, PMID:17572079, PMID:17606709, PMID:18208484, PMID:18307025, PMID:18453682, PMID:18511570, PMID:18555592, PMID:19012332, PMID:19101993, PMID:19147582, PMID:19171880, PMID:19336573, PMID:19468865, PMID:19556618, PMID:19681600, PMID:19850740, PMID:19913028, PMID:20028212, PMID:20118236, PMID:20127978, PMID:20128691, PMID:20234365, PMID:20407015, PMID:20505364, PMID:20506564, PMID:20522432, PMID:20805372, PMID:20972454, PMID:21059199, PMID:21159183, PMID:21232794, PMID:21305319, PMID:21319261, PMID:21343334, PMID:21356188, PMID:21519010, PMID:21626334, PMID:21674059, PMID:21761402, PMID:22090360, PMID:22138691, PMID:22186996, PMID:22672556, PMID:22710932, PMID:22844452, PMID:22887876, PMID:22915647, PMID:22923379, PMID:22983585, PMID:23031740, PMID:23161690, PMID:23165212, PMID:23175693, PMID:23246812, PMID:23259501, PMID:23315175, PMID:23630318, PMID:23797736, PMID:23894400, PMID:24033266, PMID:24256616, PMID:24381225, PMID:24384472, PMID:24395441, PMID:24487413, PMID:24573247, PMID:24641375, PMID:24702488, PMID:24728327, PMID:24766216, PMID:25293557, PMID:25401301, PMID:25503501, PMID:25584008, PMID:25584637, PMID:25619955, PMID:25741868, PMID:25787918, PMID:25896519, PMID:25952993, PMID:25980754, PMID:26014290, PMID:26022348, PMID:26230955, PMID:26270727, PMID:26467025, PMID:26554828, PMID:26556299, PMID:26585234, PMID:26619011, PMID:26659639, PMID:26787237, PMID:26845104, PMID:26878390, PMID:26911350, PMID:26976419, PMID:27022024, PMID:27077130, PMID:27189670, PMID:27276561, PMID:27463065, PMID:27493922, PMID:27533082, PMID:27616075, PMID:27622479, PMID:27680515, PMID:27895058, PMID:27959731, PMID:28135145, PMID:28279309, PMID:28369373, PMID:28472496, PMID:28492532, PMID:28802053, PMID:28861920, PMID:28915717, PMID:28975465, PMID:29070607, PMID:29126202, PMID:29324801, PMID:29489754, PMID:29753700, PMID:29979965, PMID:30128536, PMID:30216591, PMID:30224644, PMID:30297838, PMID:30306255, PMID:30311369, PMID:30327374, PMID:30352134, PMID:30450585, PMID:30720243, PMID:31775759, PMID:17094408 RGD:2290544 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TP73 tumor protein p73 IAGP RGD PMID:9796703 RGD:2291837 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G TSC1 TSC complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 9:132,891,349...132,945,269
Ensembl chr 9:132,891,348...132,946,874
JBrowse link
G TSC2 TSC complex subunit 2 treatment ISO DNA:nonsense mutations;missense mutations; splice-site mutation:multiple RGD PMID:10096549, PMID:10029074, PMID:18695678 RGD:11568655, RGD:68666, RGD:11568661 NCBI chr16:2,047,804...2,089,491
Ensembl chr16:2,047,967...2,089,491
JBrowse link
G TXNIP thioredoxin interacting protein ISO DNA, mRNA, protein:hypermethylation, decreased expression:promoter, kidney RGD PMID:15834431 RGD:1642756 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
G TYMP thymidine phosphorylase severity IEP protein:increased expression:kidney RGD PMID:16861722, PMID:12614261 RGD:2293717, RGD:2293723 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
JBrowse link
G UNC5C unc-5 netrin receptor C EXP CTD Direct Evidence: marker/mechanism CTD PMID:21600761 NCBI chr 4:95,162,504...95,549,210
Ensembl chr 4:95,162,504...95,549,206
JBrowse link
G VDR vitamin D receptor IEA GAD PMID:15118671 RGD:1331525 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression IEP RGD PMID:19755989 RGD:2315455 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VEGFC vascular endothelial growth factor C IEP RGD PMID:19500329 RGD:2315476 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922
JBrowse link
G VHL von Hippel-Lindau tumor suppressor IAGP
EXP
ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:9137812, PMID:10340905, PMID:11171960, PMID:11986208, PMID:15177666, PMID:15607616, PMID:19270817, PMID:19473641, PMID:21097529, PMID:22138691, PMID:23797736, PMID:24755467, PMID:28492532, PMID:29124493, PMID:15932632 RGD:1580369 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,008...10,152,220
Ensembl chr 3:10,141,008...10,152,220
JBrowse link
G VMO1 vitelline membrane outer layer 1 homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:4,785,285...4,786,364
Ensembl chr17:4,785,285...4,786,433
JBrowse link
G VWF von Willebrand factor disease_progression IEP protein:increased expression:plasma RGD PMID:21953673 RGD:7207032 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
Ensembl chr12:5,948,877...6,124,770
JBrowse link
G WIF1 WNT inhibitory factor 1 IDA DNA:hypermethylation:promoter RGD PMID:17145819 RGD:2291869 NCBI chr12:65,050,626...65,121,305
Ensembl chr12:65,050,626...65,121,305
JBrowse link
G WNT11 Wnt family member 11 IEP mRNA:increased expression:tumor:increased in a single case RGD PMID:11712081 RGD:2299947 NCBI chr11:76,186,325...76,210,842
Ensembl chr11:76,186,325...76,210,736
JBrowse link
G XIAP X-linked inhibitor of apoptosis disease_progression IEP protein:increased expression:kidney RGD PMID:17332931 RGD:2315854 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,724...123,913,976
Ensembl chr  X:123,859,724...123,913,976
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility IAGP DNA:SNP: :p.R399Q RGD PMID:16510122 RGD:2302577 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,040...43,580,473
Ensembl chr19:43,543,040...43,580,473
JBrowse link
G YIPF3 Yip1 domain family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 6:43,511,832...43,516,926
Ensembl chr 6:43,511,832...43,516,985
JBrowse link
G ZNF536 zinc finger protein 536 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr19:30,224,236...30,713,586
Ensembl chr19:30,228,290...30,713,538
JBrowse link
G ZNF765 zinc finger protein 765 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr19:53,395,149...53,427,321
Ensembl chr19:53,389,793...53,430,413
JBrowse link
G ZNF804A zinc finger protein 804A EXP CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 2:184,598,529...184,939,492
Ensembl chr 2:184,598,529...184,939,492
JBrowse link
Renal Cell Carcinoma 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTOR mechanistic target of rapamycin kinase IAGP ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:24631838, PMID:25741868, PMID:26018084, PMID:26619011, PMID:27159400, PMID:27830187 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1654209, PMID:2278970, PMID:2674680, PMID:3122217, PMID:6587382, PMID:8120410, PMID:10821536, PMID:12460918, PMID:12727991, PMID:14508525, PMID:15899789, PMID:16273091, PMID:16291983, PMID:16434492, PMID:17699718, PMID:18390968, PMID:18633438, PMID:18668139, PMID:18948947, PMID:19075190, PMID:19657110, PMID:19880792, PMID:20130576, PMID:20149136, PMID:20179705, PMID:20406486, PMID:20619739, PMID:20736745, PMID:21107323, PMID:21305640, PMID:21576590, PMID:21729679, PMID:21829508, PMID:22407852, PMID:22499344, PMID:22718121, PMID:22761467, PMID:22773810, PMID:23076151, PMID:23392294, PMID:23400451, PMID:23414587, PMID:23515407, PMID:23538902, PMID:23569304, PMID:23614898, PMID:24006476, PMID:24033266, PMID:24148783, PMID:24370118, PMID:24671188, PMID:25157968, PMID:25348872, PMID:25695684, PMID:26619011, PMID:26821351, PMID:27050078, PMID:28492532, PMID:28780248 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:21824802, PMID:22162582, PMID:22162589, PMID:22271473, PMID:22658544, PMID:22729222, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23100325, PMID:23408298, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24782230, PMID:25157968, PMID:25741868, PMID:26266975, PMID:26266985, PMID:26619011, PMID:26822237, PMID:27626068, PMID:27631024, PMID:28492532, PMID:29446767, PMID:31775759 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:9467011, PMID:9915974, PMID:10866302, PMID:11504908, PMID:11875759, PMID:16773562, PMID:17526801, PMID:17942903, PMID:18767981, PMID:19457929, PMID:20085938, PMID:20300775, PMID:21659347, PMID:21822720, PMID:21824802, PMID:21828076, PMID:22266152, PMID:22320991, PMID:22327138, PMID:22595938, PMID:23335809, PMID:23399955, PMID:23470840, PMID:24778394, PMID:25157968, PMID:25527629, PMID:25741868, PMID:26619011, PMID:26798346, PMID:27477328, PMID:27535533, PMID:28475857, PMID:28492532, PMID:29359449, PMID:29706350 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26619011 NCBI chr11:66,052,361...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1349175, PMID:1565143, PMID:1565144, PMID:1644930, PMID:1737852, PMID:7651740, PMID:7707106, PMID:7732013, PMID:7887414, PMID:8023157, PMID:8080050, PMID:8118819, PMID:8401536, PMID:8633021, PMID:8718514, PMID:8829627, PMID:8869100, PMID:9096669, PMID:9242456, PMID:9290701, PMID:9546439, PMID:9572492, PMID:9635828, PMID:9662334, PMID:9667734, PMID:10064694, PMID:10366100, PMID:10432928, PMID:10589545, PMID:10753186, PMID:10761705, PMID:10864200, PMID:10922393, PMID:11370630, PMID:11429705, PMID:11782540, PMID:11793474, PMID:11896595, PMID:11920788, PMID:11920959, PMID:12826609, PMID:12909720, PMID:12917626, PMID:14584079, PMID:15037740, PMID:15161705, PMID:15850016, PMID:15925506, PMID:15977174, PMID:15982667, PMID:16312222, PMID:16494995, PMID:16508005, PMID:16736287, PMID:16818505, PMID:16861262, PMID:17015838, PMID:17390010, PMID:17401428, PMID:17541742, PMID:17572079, PMID:17606709, PMID:18208484, PMID:18307025, PMID:18453682, PMID:18511570, PMID:18555592, PMID:19012332, PMID:19101993, PMID:19147582, PMID:19171880, PMID:19336573, PMID:19468865, PMID:19556618, PMID:19681600, PMID:19850740, PMID:19913028, PMID:20028212, PMID:20118236, PMID:20127978, PMID:20128691, PMID:20234365, PMID:20407015, PMID:20505364, PMID:20506564, PMID:20522432, PMID:20805372, PMID:20972454, PMID:21059199, PMID:21159183, PMID:21232794, PMID:21305319, PMID:21319261, PMID:21343334, PMID:21356188, PMID:21519010, PMID:21626334, PMID:21674059, PMID:21761402, PMID:22090360, PMID:22186996, PMID:22672556, PMID:22710932, PMID:22844452, PMID:22887876, PMID:22915647, PMID:22923379, PMID:22983585, PMID:23031740, PMID:23161690, PMID:23165212, PMID:23175693, PMID:23246812, PMID:23259501, PMID:23315175, PMID:23630318, PMID:23894400, PMID:24033266, PMID:24256616, PMID:24381225, PMID:24384472, PMID:24395441, PMID:24487413, PMID:24573247, PMID:24641375, PMID:24702488, PMID:24728327, PMID:24766216, PMID:25293557, PMID:25503501, PMID:25584008, PMID:25584637, PMID:25619955, PMID:25741868, PMID:25787918, PMID:25896519, PMID:25952993, PMID:25980754, PMID:26014290, PMID:26022348, PMID:26230955, PMID:26270727, PMID:26467025, PMID:26554828, PMID:26556299, PMID:26585234, PMID:26619011, PMID:26659639, PMID:26787237, PMID:26845104, PMID:26878390, PMID:26911350, PMID:26976419, PMID:27022024, PMID:27077130, PMID:27189670, PMID:27276561, PMID:27463065, PMID:27493922, PMID:27533082, PMID:27616075, PMID:27622479, PMID:27680515, PMID:27895058, PMID:27959731, PMID:28135145, PMID:28279309, PMID:28369373, PMID:28472496, PMID:28492532, PMID:28802053, PMID:28861920, PMID:28915717, PMID:28975465, PMID:29070607, PMID:29126202, PMID:29324801, PMID:29489754, PMID:29753700, PMID:29979965, PMID:30128536, PMID:30216591, PMID:30224644, PMID:30297838, PMID:30306255, PMID:30311369, PMID:30327374, PMID:30352134, PMID:30450585, PMID:30720243, PMID:31775759 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
Renal Cell Carcinoma, Xp11-Associated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TFE3 transcription factor binding to IGHM enhancer 3 IAGP OMIM NCBI chr  X:49,028,726...49,043,357
Ensembl chr  X:49,028,726...49,043,410
JBrowse link
Sporadic Papillary Renal Cell Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458, PMID:26619011 NCBI chr  X:47,561,205...47,571,908
Ensembl chr  X:47,561,100...47,571,920
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:12068308, PMID:12198537, PMID:12447372, PMID:12460918, PMID:12460919, PMID:12619120, PMID:12644542, PMID:12670889, PMID:12794760, PMID:12960123, PMID:14513361, PMID:14602780, PMID:14679157, PMID:15001635, PMID:15035987, PMID:15126572, PMID:15181070, PMID:15342696, PMID:15356022, PMID:15386408, PMID:15687339, PMID:15998781, PMID:16015629, PMID:16174717, PMID:16187918, PMID:16772349, PMID:17374713, PMID:17488796, PMID:17785355, PMID:18398503, PMID:19001320, PMID:19010912, PMID:19018267, PMID:19238210, PMID:19404918, PMID:19537845, PMID:19561230, PMID:20008640, PMID:20350999, PMID:20413299, PMID:20619739, PMID:20630094, PMID:20818844, PMID:20823850, PMID:20857202, PMID:21107320, PMID:21107323, PMID:21129611, PMID:21156289, PMID:21163703, PMID:21426297, PMID:21483012, PMID:21502544, PMID:21639808, PMID:21641636, PMID:21683865, PMID:21975775, PMID:22038996, PMID:22048237, PMID:22113612, PMID:22180495, PMID:22281684, PMID:22351686, PMID:22356324, PMID:22389471, PMID:22448344, PMID:22536370, PMID:22586120, PMID:22608338, PMID:22649091, PMID:22663011, PMID:22735384, PMID:22743296, PMID:22773810, PMID:22805292, PMID:22972589, PMID:22997239, PMID:23020132, PMID:23031422, PMID:23251002, PMID:23302800, PMID:23325582, PMID:23470635, PMID:23524406, PMID:23549875, PMID:23614898, PMID:23685455, PMID:23812671, PMID:23833300, PMID:23845441, PMID:23918947, PMID:24033266, PMID:24107445, PMID:24112392, PMID:24163374, PMID:24388723, PMID:24446311, PMID:24508103, PMID:24512911, PMID:24576830, PMID:24583796, PMID:24586605, PMID:24594804, PMID:24670642, PMID:24717435, PMID:25024077, PMID:25037139, PMID:25079330, PMID:25157968, PMID:25265492, PMID:25265494, PMID:25370471, PMID:25399551, PMID:25950823, PMID:25989278, PMID:26619011, PMID:26678033, PMID:27404270, PMID:27480103, PMID:28854169, PMID:28891408, PMID:29925953, PMID:31779674, PMID:31891627 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:25741868, PMID:26619011 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839, PMID:22046346, PMID:23220880, PMID:25157968, PMID:26619011 NCBI chr17:39,688,094...39,728,660
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 4:152,320,544...152,536,873
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:8589699, PMID:8845844, PMID:9438390, PMID:9843049, PMID:10471491, PMID:11038465, PMID:11429702, PMID:11879084, PMID:15772091, PMID:17384684, PMID:19088846, PMID:19331127, PMID:19381019, PMID:19749790, PMID:20542753, PMID:21273588, PMID:22869148, PMID:23200862, PMID:24476948, PMID:25157968, PMID:25606676, PMID:25741868, PMID:26619011, PMID:28249712, PMID:28492532, PMID:30311386 NCBI chr 4:1,793,293...1,808,872
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980, PMID:12210337, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17250658, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19371735, PMID:19382114, PMID:19669404, PMID:20660566, PMID:20979192, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22926243, PMID:23751039, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:25157968, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980, PMID:12210337, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17250658, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19371735, PMID:19382114, PMID:19669404, PMID:20660566, PMID:20979192, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22926243, PMID:23751039, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:25157968, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:31775759 NCBI chr11:518,967...554,916
Ensembl chr11:537,527...554,912
JBrowse link
G MTOR mechanistic target of rapamycin kinase IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24631838, PMID:26018084, PMID:26619011, PMID:27159400, PMID:27830187 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity IEP mRNA:increased expression:renal cortex (human)
protein:increased expression:kidney (human)
RGD PMID:19384955, PMID:17409424 RGD:7240562, RGD:7240563 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:16847462, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:22162582, PMID:22162589, PMID:22228622, PMID:22271473, PMID:22357840, PMID:22658544, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23246288, PMID:23408298, PMID:23754335, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24497998, PMID:24559322, PMID:25157968, PMID:25557259, PMID:25741868, PMID:26301495, PMID:26593112, PMID:26619011, PMID:26851524, PMID:27426476, PMID:27631024, PMID:27870750, PMID:28941273, PMID:29446767, PMID:31775759 NCBI chr 3:179,148,114...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G RHEB Ras homolog, mTORC1 binding IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:1565143, PMID:7887414, PMID:8023157, PMID:8118819, PMID:8242631, PMID:8401536, PMID:8633021, PMID:9242456, PMID:9627118, PMID:9662334, PMID:10432928, PMID:10589545, PMID:10922393, PMID:12826609, PMID:14559903, PMID:15037740, PMID:15977174, PMID:16312222, PMID:16861262, PMID:17015838, PMID:17390010, PMID:17606709, PMID:18307025, PMID:19101993, PMID:19556618, PMID:20028212, PMID:20128691, PMID:20234365, PMID:20308654, PMID:20407015, PMID:20805372, PMID:21056685, PMID:21343334, PMID:21356188, PMID:21483000, PMID:21514416, PMID:21761402, PMID:22265402, PMID:22887876, PMID:22923379, PMID:23031740, PMID:23259501, PMID:23315175, PMID:23630318, PMID:24381225, PMID:24395441, PMID:24487413, PMID:24641375, PMID:24702488, PMID:25584008, PMID:25741868, PMID:25945745, PMID:26425688, PMID:26467025, PMID:26585234, PMID:26619011, PMID:26911350, PMID:27189670, PMID:28279309, PMID:28369373, PMID:28476805, PMID:28492532, PMID:28724667, PMID:28975465, PMID:29979965, PMID:30224644, PMID:30297838, PMID:30720243, PMID:31775759 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18864
    disease of cellular proliferation 6853
      Neoplasms by Histologic Type 4078
        cell type cancer 3455
          carcinoma 2217
            renal carcinoma 373
              kidney carcinoma in situ 0
              renal cell carcinoma + 367
              renal pelvis carcinoma + 0
Path 2
Term Annotations click to browse term
  disease 18864
    disease of anatomical entity 17349
      Urogenital Diseases 4645
        urinary system disease 1894
          kidney disease 1679
            Kidney Neoplasms 459
              kidney cancer 432
                renal carcinoma 373
                  kidney carcinoma in situ 0
                  renal cell carcinoma + 367
                  renal pelvis carcinoma + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.