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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:renal carcinoma
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Accession:DOID:4451 term browser browse the term
Definition:A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products). (DO)
Synonyms:exact_synonym: carcinoma of kidney;   kidney carcinoma
 primary_id: RDO:9002264
 xref: NCI:C124802;   NCI:C9384
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
renal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOSL1 FOS like 1, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr11:61,252,513...61,261,032
Ensembl chr11:64,581,841...64,589,304
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr2A:28,392,328...28,416,838
Ensembl chr2A:28,485,613...28,498,397
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr19:12,353,760...12,355,598
Ensembl chr19:13,097,931...13,098,974
JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO mRNA:increased expression:kidney RGD PMID:9405228 RGD:2293758 NCBI chr19:17,755,331...17,757,164 JBrowse link
G LETMD1 LETM1 domain containing 1 ISO mRNA, protein:increased expression:kidney RGD PMID:12879013 RGD:2314918 NCBI chr12:37,685,741...37,705,104
Ensembl chr12:38,597,728...38,609,810
JBrowse link
G MCPH1 microcephalin 1 ISO protein:decreased expression:kidney (human) RGD PMID:25197360 RGD:9589037 NCBI chr 8:624,877...877,839
Ensembl chr 8:6,409,072...6,646,394
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Kidney Carcinoma ClinVar PMID:9140397 PMID:9563489 PMID:9731534 PMID:9826708 PMID:10327054 More... NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Kidney Carcinoma
ClinVar Annotator: match by term: Renal carcinoma
ClinVar PMID:24622468 PMID:24631838 PMID:26018084 PMID:26619011 PMID:27159400 More... NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
chromophobe renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:9392505 PMID:9754819 PMID:10966642 PMID:11393552 PMID:15649945 More... NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911
JBrowse link
G HNF1B HNF1 homeobox B ISO ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:15649945 PMID:16371430 PMID:25536396 PMID:25700310 PMID:25741868 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863
JBrowse link
clear cell renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO mRNA:increased expression:renal cortex (human) RGD PMID:21947243 RGD:7244181 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 ISO RGD PMID:28672194 RGD:14696810 NCBI chr12:35,078,290...35,089,480 JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b ISO RGD PMID:28672194 RGD:14696810 NCBI chr 1:114,110,749...114,122,715
Ensembl chr 1:126,224,725...126,235,897
JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP ISO RGD PMID:28672194 RGD:14696810 NCBI chr21:20,270,442...20,282,865 JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 disease_progression ISO RGD PMID:23788753 RGD:13506731 NCBI chr14:14,689,398...14,716,301
Ensembl chr14:32,880,324...32,907,241
JBrowse link
G ENG endoglin severity ISO protein:increased expression:tumor, vasculature (human)
protein:decreased expression:kidney, tumor (human)
RGD PMID:16536758 PMID:22204709 RGD:7248775 RGD:7248780 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G EP300 E1A binding protein p300 severity ISO mRNA, protein:increased expression:kidney
mRNA:altered expression:kidney, tumor (human)
RGD PMID:23029358 PMID:28551630 RGD:15036804 RGD:7296925 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:brain RGD PMID:22065054 RGD:6893520 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr 5:175,804,728...175,852,703
Ensembl chr 5:183,115,856...183,149,006
JBrowse link
G GATA1 GATA binding protein 1 disease_progression ISO RGD PMID:25230694 RGD:149735195 NCBI chr  X:41,088,724...41,092,190
Ensembl chr  X:48,945,394...48,953,126
JBrowse link
G GATA2 GATA binding protein 2 disease_progression ISO RGD PMID:25230694 RGD:149735195 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035
JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:10383153 RGD:6906878 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:8866553 PMID:8945470 PMID:9032114 PMID:9045858 PMID:9075818 More... NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO xenograph of human clear cell renal cancer cells in mouse RGD PMID:19509240 RGD:7242921 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G KAT8 lysine acetyltransferase 8 ISO mRNA, protein:decreased expression:kidney (human) RGD PMID:23394073 RGD:9586034 NCBI chr16:23,837,540...23,851,376
Ensembl chr16:31,486,098...31,500,185
JBrowse link
G MMP12 matrix metallopeptidase 12 ISO RGD PMID:11576837 RGD:2290421 NCBI chr11:97,809,644...97,822,063
Ensembl chr11:101,294,475...101,306,762
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
severity
ISO DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) RGD PMID:20039875 PMID:21489764 RGD:6893474 RGD:6893632 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity ISO protein:increased expression:kidney (human) RGD PMID:21881486 RGD:7207420 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:10987279 NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335
JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 disease_progression ISO RGD PMID:25744653 RGD:13504816 NCBI chr19:36,224,442...36,278,371
Ensembl chr19:44,816,601...44,825,827
JBrowse link
G PAK6 p21 (RAC1) activated kinase 6 disease_progression ISO RGD PMID:24715215 RGD:13506722 NCBI chr15:19,173,171...19,211,572
Ensembl chr15:37,453,802...37,465,119
JBrowse link
G PBRM1 polybromo 1 ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:25911086 NCBI chr 3:52,487,083...52,626,418
Ensembl chr 3:53,718,051...53,850,146
JBrowse link
G PDGFB platelet derived growth factor subunit B disease_progression ISO RGD PMID:23879920 PMID:25766258 RGD:13504817 RGD:13506650 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PML PML nuclear body scaffold ISO protein:decreased expression:kidney (human) RGD PMID:25293974 RGD:41404694 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase severity ISO DNA:mutations:multiple (human)
DNA:SNPs,loss of heterozygosity:multiple (human)
RGD PMID:26864202 PMID:26891804 RGD:150429635 RGD:150429640 NCBI chr 3:46,916,615...47,064,046
Ensembl chr 3:48,018,517...48,163,999
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr17:52,083,676...52,087,454
Ensembl chr17:56,937,295...56,944,425
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr17:70,809,931...70,813,191
Ensembl chr17:76,375,957...76,379,759
JBrowse link
G SRSF4 serine and arginine rich splicing factor 4 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 1:28,418,297...28,452,595
Ensembl chr 1:29,444,269...29,478,035
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr14:50,320,820...50,365,650
Ensembl chr14:69,230,730...69,236,596
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr20:39,795,659...39,801,864
Ensembl chr20:40,888,560...40,891,853
JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr2A:38,780,879...38,787,470
Ensembl chr2A:39,536,731...39,545,562
JBrowse link
G TP53 tumor protein p53 ISO mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
hereditary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE1 deoxyribonuclease 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr16:2,532,281...2,583,408
Ensembl chr16:3,708,189...3,758,615
JBrowse link
G EGF epidermal growth factor ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar PMID:28492532 PMID:28546994 NCBI chr 5:192,786...234,089 JBrowse link
G TRAP1 TNF receptor associated protein 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr16:2,578,483...2,637,996
Ensembl chr16:3,753,799...3,786,429
JBrowse link
nonpapillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK1 calcium/calmodulin dependent protein kinase I ISO ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary ClinVar NCBI chr 3:9,708,782...9,721,433
Ensembl chr 3:9,945,609...9,959,560
JBrowse link
G FLCN folliculin ISO ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary ClinVar PMID:15805188 PMID:15852235 PMID:16199547 PMID:18234728 PMID:19457309 More... NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary ClinVar PMID:25741868 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary ClinVar NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335
JBrowse link
papillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:39,997,026...40,007,783
Ensembl chr  X:47,893,153...47,904,643
JBrowse link
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:109,330,983...109,397,864
Ensembl chr 7:122,025,611...122,091,923
JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:10571946 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:108,835,083...108,889,112
Ensembl chr 7:121,551,401...121,584,566
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CFTR CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26822237 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G ELOC elongin C ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 8:70,479,805...70,506,142
Ensembl chr 8:72,121,035...72,151,085
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:8589699 PMID:8845844 PMID:9438390 PMID:9843049 PMID:10471491 More... NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:514,227...559,838
Ensembl chr11:575,495...588,750
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO OMIM NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G MSH2 mutS homolog 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:18325052 PMID:21926548 PMID:24506336 PMID:24763289 PMID:25637381 More... NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar PMID:24631838 PMID:25741868 PMID:26018084 PMID:26619011 PMID:27159400 More... NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G PRCC proline rich mitotic checkpoint control factor ISO OMIM NCBI chr 1:132,110,795...132,144,039
Ensembl chr 1:135,933,269...135,966,483
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G RHEB Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 7:143,054,747...143,108,011 JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:18728283 PMID:19576851 PMID:22835832 PMID:24055113 PMID:24092654 More... NCBI chr 1:15,962,383...15,998,056
Ensembl chr 1:17,018,542...17,054,509
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr2B:84,633,272...84,678,602
Ensembl chr2B:202,530,200...202,573,346
JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr11:61,416,764...61,433,334
Ensembl chr11:64,743,629...64,759,772
JBrowse link
G ST7 suppression of tumorigenicity 7 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:108,922,652...109,197,805
Ensembl chr 7:121,680,200...121,896,175
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar PMID:1349175 PMID:1565143 PMID:1565144 PMID:1644930 PMID:1737852 More... NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:7660122 PMID:7728151 PMID:7784063 PMID:7987306 PMID:7987327 More... NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234
JBrowse link
G WNT2 Wnt family member 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862
JBrowse link
renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 disease_progression ISO DNA:polymorphism: :3435C>T (human) RGD PMID:12089380 PMID:17177989 RGD:2315557 RGD:2315559 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) susceptibility ISO DNA:polymorphism: :p.Q141K (human) RGD PMID:15906349 RGD:2315569 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
G ACY1 aminoacylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 3:51,924,889...51,930,638
Ensembl chr 3:53,144,802...53,158,941
JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 severity ISO RGD PMID:21511296 RGD:13831349 NCBI chr 8:139,154,065...139,251,115
Ensembl chr 8:142,220,827...142,301,070
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:29723618 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:1714107 RGD:2292042 NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391
JBrowse link
G AGTR1 angiotensin II receptor type 1 severity ISO protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380
JBrowse link
G AGTR2 angiotensin II receptor type 2 disease_progression ISO protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685
JBrowse link
G AHNAK AHNAK nucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr11:57,791,927...57,904,277
Ensembl chr11:61,149,485...61,249,137
JBrowse link
G AKAP13 A-kinase anchoring protein 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:kidney RGD PMID:17681738 RGD:1643331 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G AKT3 AKT serine/threonine kinase 3 susceptibility ISO DNA:missense mutation:exon, intron:multiple RGD PMID:23378641 RGD:13503319 NCBI chr 1:219,107,482...219,463,140
Ensembl chr 1:224,480,784...224,824,838
JBrowse link
G ALAD aminolevulinate dehydratase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21799727 NCBI chr 9:84,488,339...84,503,360
Ensembl chr 9:112,859,171...112,873,784
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 9:51,737,305...51,916,648
Ensembl chr 9:71,680,890...71,814,085
JBrowse link
G ALK ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22743654 NCBI chr2A:29,196,195...29,930,062
Ensembl chr2A:29,276,041...30,006,735
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:kidney RGD PMID:14654968 RGD:2315610 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr17:43,569,858...43,588,039
Ensembl chr17:48,302,450...48,317,029
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G AMACR alpha-methylacyl-CoA racemase ISO RGD PMID:14707866 RGD:2315633 NCBI chr 5:76,336,631...76,358,724
Ensembl chr 5:81,687,891...81,742,003
JBrowse link
G ANG angiogenin ISO protein:increased expression:serum RGD PMID:18808740 RGD:2325699 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393
JBrowse link
G ANGPT1 angiopoietin 1 severity ISO mRNA:altered expression:kidney RGD PMID:17505508 RGD:1643335 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783
JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:14587099 RGD:7421570 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G ANXA2 annexin A2 ISO RGD PMID:14587099 RGD:7421570 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250
JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr2A:69,686,651...69,869,340
Ensembl chr2A:70,902,260...70,986,917
JBrowse link
G AP5M1 adaptor related protein complex 5 subunit mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr14:37,839,766...37,869,926
Ensembl chr14:56,110,452...56,131,921
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939
JBrowse link
G APC APC regulator of WNT signaling pathway severity
disease_progression
onset
ISO DNA:LOH: :
DNA,protein:LOH,decreased expression: :
RGD PMID:10426194 PMID:15203750 PMID:16116480 RGD:7242056 RGD:7242059 RGD:7242060 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G APRT adenine phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr16:69,522,628...69,525,138
Ensembl chr16:89,179,020...89,181,504
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator treatment ISO DNA:missense mutation: :pF446L (human) RGD PMID:27595394 RGD:13503335 NCBI chr 1:126,160,017...126,226,222
Ensembl chr 1:129,809,431...129,875,629
JBrowse link
G ASB15 ankyrin repeat and SOCS box containing 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 7:115,595,751...115,631,803
Ensembl chr 7:128,285,366...128,314,610
JBrowse link
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 7:109,330,983...109,397,864
Ensembl chr 7:122,025,611...122,091,923
JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 ISO DNA:hypermethylation:promoter RGD PMID:21132003 RGD:14696812 NCBI chr12:35,078,290...35,089,480 JBrowse link
G AURKA aurora kinase A ISO mRNA, protein:increased expression:kidney RGD PMID:17349527 RGD:1643346 NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339
JBrowse link
G BAD BCL2 associated agonist of cell death ISO RGD PMID:15851405 RGD:2292677 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAK1 BCL2 antagonist/killer 1 severity ISO RGD PMID:9894249 RGD:2315703 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAP1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:22683710 PMID:23797736 PMID:25231345 NCBI chr 3:52,344,067...52,352,187
Ensembl chr 3:53,573,785...53,581,943
JBrowse link
G BCHE butyrylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr 3:162,794,184...162,858,574
Ensembl chr 3:170,845,494...170,911,481
JBrowse link
G BCL2 BCL2 apoptosis regulator disease_progression ISO RGD PMID:17482919 PMID:18283311 RGD:2293019 RGD:2298896 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:12025227 RGD:1643483 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G BIK BCL2 interacting killer ISO protein:decreased expression:kidney RGD PMID:16322756 RGD:14394818 NCBI chr22:23,994,256...24,014,244
Ensembl chr22:42,207,149...42,213,022
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 disease_progression ISO mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr11:97,298,736...97,324,966
Ensembl chr11:100,793,036...100,822,421
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ISO mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr11:97,269,778...97,290,112
Ensembl chr11:100,763,274...100,785,194
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression ISO mRNA:splice variant
CTD Direct Evidence: therapeutic
protein:increased expression:kidney
RGD
CTD
PMID:12115583 PMID:16188142 PMID:17363528 RGD:2293102 RGD:2293108 NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159
JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17437058 PMID:25401301 NCBI chr20:59,618,530...59,623,612
Ensembl chr20:61,157,302...61,161,932
JBrowse link
G BMP4 bone morphogenetic protein 4 severity ISO RGD PMID:17644140 RGD:1643589 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO mRNA,protein:increased expression:kidney RGD PMID:20016212 RGD:7242419 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G BMP7 bone morphogenetic protein 7 disease_progression ISO RGD PMID:17644140 RGD:1643589 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G BTG2 BTG anti-proliferation factor 2 ISO mRNA:decreased expression:kidney RGD PMID:14996721 RGD:2289069 NCBI chr 1:178,907,317...178,911,410
Ensembl chr 1:183,201,297...183,205,404
JBrowse link
G BTG3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19221000 NCBI chr21:4,327,813...4,347,053
Ensembl chr21:17,693,067...17,712,280
JBrowse link
G CA9 carbonic anhydrase 9 disease_progression ISO DNA, mRNA:hypomethylation, increased expression:promoter, kidney
protein:increased expression:serum, urine
RGD PMID:11506497 PMID:12883698 PMID:12966427 PMID:18464292 RGD:2293191 RGD:2293198 RGD:2293199 RGD:2293201 NCBI chr 9:35,525,877...35,533,159
Ensembl chr 9:36,328,303...36,335,340
JBrowse link
G CAPG capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr2A:85,447,296...85,466,677
Ensembl chr2A:86,997,891...87,016,263
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 7:108,835,083...108,889,112
Ensembl chr 7:121,551,401...121,584,566
JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999
JBrowse link
G CASP2 caspase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958
JBrowse link
G CASP3 caspase 3 ISO RGD PMID:17513560 RGD:2293308 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CAV1 caveolin 1 disease_progression ISO protein:increased expression:kidney
ClinVar Annotator: match by term: Renal cell carcinoma
RGD
ClinVar
PMID:15247769 PMID:28492532 RGD:2289107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CCNB1 cyclin B1 disease_progression ISO protein:increased expression:kidney RGD PMID:16557593 RGD:2315941 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G CCND1 cyclin D1 ISO DNA:polymorphism RGD PMID:15538282 PMID:17924468 RGD:2289127 RGD:2289130 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CCND3 cyclin D3 disease_progression ISO RGD PMID:18679818 RGD:2316007 NCBI chr 6:41,518,421...41,630,103
Ensembl chr 6:42,820,569...42,827,498
JBrowse link
G CCNE1 cyclin E1 ISO mRNA, protein:increased expression:kidney RGD PMID:17726548 RGD:2289228 NCBI chr19:26,739,285...26,751,630
Ensembl chr19:35,496,700...35,510,295
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:12594303 PMID:15282531 PMID:20426873 RGD:11522744 RGD:7248440 RGD:7248724 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G CD44 CD44 molecule (Indian blood group) severity
disease_progression
ISO protein:increased expression:kidney RGD PMID:12833185 PMID:17284111 RGD:2289351 RGD:2289360 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009
JBrowse link
G CD46 CD46 molecule ISO protein:decreased expression:tumor:expression associated with presence of complement C3d on tumor cells (p<0.02) and with tumor stage (p<0.04) RGD PMID:10744069 RGD:2293550 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G CDC14B cell division cycle 14B severity ISO mRNA:decreased expression:kidney: RGD PMID:24619757 RGD:10059341 NCBI chr 9:67,596,037...67,715,668 JBrowse link
G CDH1 cadherin 1 onset
disease_progression
ISO DNA:LOH: :
protein:decreased expression, altered localization:kidney, nucleus
RGD PMID:15203750 PMID:17906660 RGD:2289489 RGD:7242059 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488
JBrowse link
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:16740772 RGD:2293561 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945
JBrowse link
G CDK4 cyclin dependent kinase 4 ISO protein:increased expression:kidney RGD PMID:15991006 RGD:2293579 NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B disease_progression ISO protein:decreased expression:kidney
mRNA, protein:increased expression:kidney
RGD PMID:17924468 PMID:18425369 PMID:18495610 RGD:2289127 RGD:2293589 RGD:2293590 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO DNA:gene instability
DNA:deletion
DNA, protein:hypermethylation, increased expression:promoter, kidney
RGD PMID:11839561 PMID:15232742 PMID:17201148 RGD:1298747 RGD:2289680 RGD:2289699 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO DNA:loss of heterozygosity, deletion RGD PMID:10391689 RGD:7248758 NCBI chr 9:21,838,902...21,845,355
Ensembl chr 9:22,455,662...22,462,156
JBrowse link
G CFTR CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864
JBrowse link
G COMT catechol-O-methyltransferase susceptibility ISO DNA:polymorphism:exon RGD PMID:17220335 RGD:2289716 NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387
JBrowse link
G CPQ carboxypeptidase Q ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 8:93,264,536...93,883,201
Ensembl chr 8:95,599,177...95,974,029
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16254461 NCBI chr15:57,269,794...57,277,697
Ensembl chr15:76,234,401...76,242,311
JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr12:91,220,813...91,593,799 JBrowse link
G CRP C-reactive protein disease_progression ISO RGD PMID:22958305 RGD:6904212 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CRYAB crystallin alpha B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr11:106,795,406...106,800,019
Ensembl chr11:110,639,442...110,644,272
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO mRNA:increased expression:kidney RGD PMID:18592004 PMID:22052465 RGD:2299092 RGD:7257566 NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415
JBrowse link
G CSMD3 CUB and Sushi multiple domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:23797736 NCBI chr 8:108,866,817...110,077,727
Ensembl chr 8:111,423,262...112,630,306
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO DNA:SNPs:exons:rs3087243, rs231775 (human) RGD PMID:17678726 RGD:7204723 NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498
JBrowse link
G CTNNA1 catenin alpha 1 disease_progression ISO protein:decreased expression:kidney RGD PMID:9355975 RGD:2289799 NCBI chr 5:134,134,944...134,313,239
Ensembl chr 5:140,261,883...140,438,547
JBrowse link
G CTNNB1 catenin beta 1 disease_progression ISO protein:increased expression:kidney RGD PMID:11831984 PMID:15330191 RGD:2289794 RGD:2289835 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G CTSB cathepsin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:7,333,498...7,359,264 JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr11:1,789,326...1,800,524 JBrowse link
G CUL7 cullin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 6:42,629,158...42,646,279
Ensembl chr 6:43,924,408...43,942,768
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:16210641 RGD:7257682 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association ISO DNA:polymorphism: :p.I462V (human)
DNA:SNPs: :6235T>C, 4889A>G, 4887C>A (human)
RGD PMID:9631944 PMID:11115552 PMID:22000673 PMID:22296350 RGD:7257729 RGD:7296937 RGD:7296938 RGD:7296939 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr 9:58,628,872...58,836,205
Ensembl chr 9:86,681,953...86,887,958
JBrowse link
G DNHD1 dynein heavy chain domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr11:6,628,568...6,703,994
Ensembl chr11:6,312,254...6,386,993
JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 disease_progression ISO RGD PMID:15867365 RGD:2289852 NCBI chr 8:106,190,208...106,216,402
Ensembl chr 8:108,335,590...108,361,475
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr19:3,000,608...3,009,918
Ensembl chr19:3,950,772...3,960,172
JBrowse link
G EGFR epidermal growth factor receptor ISO protein:increased expression:tumor RGD PMID:18467719 RGD:2293730 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr 1:206,915,541...206,976,656 JBrowse link
G EGLN2 egl-9 family hypoxia inducible factor 2 ISO protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr19:37,842,460...37,851,465
Ensembl chr19:46,349,131...46,357,875
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 ISO protein:increased expression:serum RGD PMID:20676679 RGD:13506732 NCBI chr14:14,689,398...14,716,301
Ensembl chr14:32,880,324...32,907,241
JBrowse link
G ELOC elongin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 8:70,479,805...70,506,142
Ensembl chr 8:72,121,035...72,151,085
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12750296 PMID:21131975 RGD:10395373 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10897039 PMID:15360049 PMID:17296437 RGD:2289930 RGD:2289987 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO mRNA, protein:decreased expression:kidney RGD PMID:15360049 RGD:2289987 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006
JBrowse link
G FAAH2 fatty acid amide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr  X:49,571,209...49,781,436
Ensembl chr  X:57,734,870...57,944,524
JBrowse link
G FAM111B FAM111 trypsin like peptidase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr11:54,324,217...54,344,439
Ensembl chr11:57,779,138...57,795,819
JBrowse link
G FAS Fas cell surface death receptor ISO DNA:missense mutations:exon
protein:increased expression:serum
RGD PMID:10654915 PMID:11435457 PMID:12460460 PMID:17031406 RGD:2290099 RGD:2290131 RGD:2290132 RGD:2290133 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand ISO RGD PMID:11435457 PMID:17641033 RGD:2290051 RGD:2290132 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G FGF2 fibroblast growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:1718278 RGD:2290303 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 disease_progression ISO RGD PMID:25900027 RGD:11352663 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO DNA:translocation::t(3;8)(p14;q24.1) results in disruption of FHIT and TRC8/RNF139 genes
protein:decreased expression::reduced or negative expression in 78% of clear cell RCCs
RGD PMID:10530564 PMID:17539022 RGD:2289870 RGD:2289903 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G FLCN folliculin treatment ISO OMIM
RGD
PMID:16369488 RGD:13605606 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic
protein:increased expression:kidney, blood, myeloid cell
mRNA:increased expression:tumor:expression significantly higher in tumors than corresponding normal tissue (p=0.01), significantly correlated with VEGF expression
CTD
RGD
PMID:11846206 PMID:16596207 PMID:18566400 RGD:2289960 RGD:2301250 NCBI chr13:9,584,850...9,779,542 JBrowse link
G FMN2 formin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:215,626,889...216,023,590 JBrowse link
G FN1 fibronectin 1 severity ISO RGD PMID:20860816 RGD:7205637 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003
JBrowse link
G FPGT fucose-1-phosphate guanylyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 1:73,427,299...73,437,847
Ensembl chr 1:75,403,555...75,747,240
JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 disease_progression ISO RGD PMID:25900027 RGD:11352663 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293
JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:10962030 RGD:2301426 NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240
JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18264126 NCBI chr  X:60,490,579...60,492,606
Ensembl chr  X:70,547,110...70,547,961
JBrowse link
G GRB7 growth factor receptor bound protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:17,541,771...17,551,049
Ensembl chr17:17,758,992...17,768,290
JBrowse link
G GSR glutathione-disulfide reductase ISO protein:decreased expression:kidney: RGD PMID:18312938 RGD:7257550 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:14504370 PMID:18566013 PMID:26656529 RGD:2293845 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney
CTD
RGD
PMID:15108329 PMID:20464042 RGD:8547946 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HARS1 histidyl-tRNA synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 5:136,038,575...136,056,400
Ensembl chr 5:142,154,552...142,172,371
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression ISO RGD PMID:23352434 RGD:7245470 NCBI chr 5:152,429,337...152,459,800
Ensembl chr 5:158,413,073...158,442,481
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 susceptibility ISO DNA:polymorphisms: :-574G>T, +4259T>G (human) RGD PMID:22472081 RGD:7245505 NCBI chr 5:152,486,125...152,514,004
Ensembl chr 5:159,108,915...159,131,007
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha disease_progression ISO RGD PMID:19302703 RGD:2306222 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HNF1A HNF1 homeobox A ISO OMIM NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911
JBrowse link
G HNF1B HNF1 homeobox B ISO OMIM NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863
JBrowse link
G HOXB13 homeobox B13 disease_progression ISO DNA:hypermethylation RGD PMID:16278676 RGD:2314729 NCBI chr17:8,807,988...8,810,362
Ensembl chr17:8,994,224...8,996,598
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 5:133,934,859...133,955,048
Ensembl chr 5:140,064,207...140,084,551
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:17952403 RGD:7242846 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA,protein:increased expression:tumor:27/43 (63%) by cDNA microarray, 43/58 (74%) by immunohistochemistry RGD PMID:18076934 RGD:2290003 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO mRNA:decreased expression:kidney RGD PMID:10854235 RGD:1626565 NCBI chr 4:66,808,845...66,888,301
Ensembl chr 4:73,382,745...73,462,087
JBrowse link
G IL13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22317767 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G IL2 interleukin 2 ISO RGD PMID:21812652 RGD:5147871 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4R interleukin 4 receptor disease_progression
susceptibility
ISO DNA:polymorphism:cds:p.I50V (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12171893 PMID:22317767 PMID:30472377 RGD:7207066 RGD:7207070 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 4:134,405,934...135,213,851
Ensembl chr 4:145,706,307...146,141,029
JBrowse link
G INSR insulin receptor ISO mRNA:increased expression:tumor:isoform A RGD PMID:15753986 RGD:2290462 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO protein:increased activation:tumor:associated with early carcinogenesis--10/18 (55.5%) of pT1a cases vs 11/44 (25%) of pT1b or greater cases RGD PMID:16006965 RGD:1549443 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G JUP junction plakoglobin ISO protein:decreased expression:tumor:relative to normal kidney (p<0.001), higher expression associated with better survival rate (p<0.05)
DNA:increased methylation:promoter:significantly increased methylation vs normal kidney (p < 0.01)
RGD PMID:9891472 PMID:15701841 RGD:2291866 RGD:2291890 NCBI chr17:15,527,115...15,559,251
Ensembl chr17:15,747,163...15,777,479
JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 ISO DNA, mRNA, protein:hypermethylation, decreased expression:kidney RGD PMID:12133830 RGD:2315654 NCBI chr 9:550,713...556,230 JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 ISO protein:increased expression:kidney (human) RGD PMID:18777199 RGD:9693695 NCBI chr 1:186,233,881...186,696,509
Ensembl chr 1:191,107,256...191,562,766
JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:73,391,297...74,158,488
Ensembl chr10:76,062,047...76,820,644
JBrowse link
G KDM4C lysine demethylase 4C ISO DNA:deletion:cds (human) RGD PMID:22483639 RGD:9587741 NCBI chr 9:6,568,569...6,978,741
Ensembl chr 9:6,746,265...7,155,298
JBrowse link
G KDM5C lysine demethylase 5C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr  X:45,377,609...45,440,025
Ensembl chr  X:53,515,886...53,548,785
JBrowse link
G KDM6A lysine demethylase 6A ISO mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr  X:37,313,000...37,548,630
Ensembl chr  X:45,127,382...45,362,029
JBrowse link
G KDM6B lysine demethylase 6B ISO mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr17:7,878,783...7,889,372
Ensembl chr17:7,866,973...7,874,937
JBrowse link
G KDR kinase insert domain receptor treatment ISO RGD PMID:16763608 PMID:17332933 PMID:17653245 RGD:126925190 RGD:2301756 RGD:8552363 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr19:10,037,544...10,055,091
Ensembl chr19:10,701,303...10,717,604
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO papillary RCC only; DNA:mutation:intron:heterozygous T>A mutation in intron 17 found in 94% of cases, also protein found to be cytoplasmic not membrane-bound in 100% of cases
chromophobe RCC only; mRNA:increased expression:tumor:positive in 6/7 chromophobe RCCs, but 0/15 clear cell RCCs and 1/15 papillary RCCs
RGD PMID:15073597 PMID:15780567 RGD:2292414 RGD:2292421 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473
JBrowse link
G KLK6 kallikrein related peptidase 6 ISO protein:decreased expression:kidney RGD PMID:16340244 RGD:2314864 NCBI chr19:47,925,017...47,936,314
Ensembl chr19:56,815,073...56,826,689
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO mRNA:increased expression:kidney RGD PMID:11851621 RGD:2314914 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335
JBrowse link
G KRT32 keratin 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:15,847,992...15,857,334
Ensembl chr17:16,066,796...16,074,742
JBrowse link
G KRT7 keratin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 PMID:16927643 NCBI chr12:36,514,021...36,529,721
Ensembl chr12:37,291,244...37,307,341
JBrowse link
G KRT8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr12:35,855,367...35,863,248
Ensembl chr12:36,634,582...36,642,564
JBrowse link
G L1CAM L1 cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21097529 NCBI chr  X:143,412,303...143,437,090
Ensembl chr  X:153,298,690...153,324,228
JBrowse link
G LDHB lactate dehydrogenase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr12:64,640,994...64,663,418
Ensembl chr12:67,245,130...67,267,487
JBrowse link
G LEP leptin resistance ISO RGD PMID:19278051 RGD:6907119 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G LMAN2L lectin, mannose binding 2 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr2A:102,573,894...102,608,066
Ensembl chr2A:97,628,021...97,661,745
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:17692401 RGD:2314919 NCBI chr 5:92,247,060...92,348,900
Ensembl chr 5:97,842,110...97,893,876
JBrowse link
G LOC100971374 thioredoxin-interacting protein ISO DNA, mRNA, protein:hypermethylation, decreased expression:promoter, kidney RGD PMID:15834431 RGD:1642756 NCBI chr 1:90,007,878...90,012,055 JBrowse link
G LOC100972354 interferon alpha-2 ISO CTD Direct Evidence: therapeutic CTD PMID:8886046 NCBI chr 9:21,245,017...21,246,210
Ensembl chr 9:21,863,062...21,863,736
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein ISO RGD PMID:17031403 RGD:6907413 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LRP1B LDL receptor related protein 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr2B:17,702,178...19,611,567
Ensembl chr2B:144,382,759...146,221,243
JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G LTF lactotransferrin ISO RGD PMID:23201854 RGD:7243106 NCBI chr 3:46,337,738...46,367,476
Ensembl chr 3:47,442,440...47,471,532
JBrowse link
G M6PR mannose-6-phosphate receptor, cation dependent ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr12:9,025,394...9,034,768
Ensembl chr12:9,256,706...9,266,428
JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor susceptibility ISO RGD PMID:8649854 RGD:1599220 NCBI chr 3:51,315,948...51,320,022
Ensembl chr 3:52,548,933...52,554,343
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO protein:increased expression:tumor:13/25 cases (52%)
inhibition suppressed tumor growth and vascularization in an RCC xenograft model
RGD PMID:7664295 PMID:18172299 RGD:2292629 RGD:2292630 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 susceptibility ISO DNA:missense mutation: :multiple RGD PMID:22517515 RGD:13504815 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More... RGD:1600122 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G MGP matrix Gla protein disease_progression ISO mRNA:increased expression:tumor:inversely related to tumor size (0.025 RGD PMID:1399132 RGD:2293578 NCBI chr12:14,887,806...14,891,796
Ensembl chr12:15,284,883...15,288,523
JBrowse link
G MITF melanocyte inducing transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22012259 NCBI chr 3:69,674,064...69,902,078
Ensembl chr 3:71,037,665...71,265,445
JBrowse link
G MLH1 mutL homolog 1 ISO protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:21,686,507...21,907,247
Ensembl chr10:21,994,975...22,282,737
JBrowse link
G MMP1 matrix metallopeptidase 1 no_association
susceptibility
ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:12845675 PMID:17980059 RGD:7207023 RGD:7207082 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G MMP2 matrix metallopeptidase 2 disease_progression ISO protein:increased expression:kidney
mRNA:decreased expression:kidney
RGD PMID:17572184 PMID:18035688 RGD:2290358 RGD:2290359 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO DNA:missense mutation:cds:p.E45K rs679620 (human) RGD PMID:15319295 PMID:19551141 RGD:7207067 RGD:7241233 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA:increased expression:kidney RGD PMID:18035688 RGD:2290358 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MOK MOK protein kinase ISO mRNA:increased expression:kidney RGD PMID:15900605 RGD:7243170 NCBI chr14:82,842,769...82,925,263
Ensembl chr14:102,665,543...102,741,546
JBrowse link
G MSGN1 mesogenin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr2A:17,797,769...17,799,243
Ensembl chr2A:17,926,027...17,926,608
JBrowse link
G MSH2 mutS homolog 2 ISO protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility ISO DNA:missense mutation:cds:p.A222V (rs1801133) (human) RGD PMID:18098291 RGD:6893654 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Renal cell carcinoma
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:21881486 PMID:23797736 PMID:24631838 PMID:26018084 PMID:26619011 More... RGD:7207420 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MUC1 mucin 1, cell surface associated disease_progression ISO RGD PMID:10390012 RGD:7245968 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G MUC4 mucin 4, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 3:193,050,895...193,114,931 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO mRNA:increased expression:kidney (human)
protein:increased expression:kidney (rat)
RGD PMID:18055543 PMID:21982273 RGD:7207793 RGD:7207841 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NAV3 neuron navigator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr12:74,835,566...75,724,859
Ensembl chr12:78,192,076...78,573,746
JBrowse link
G NDRG1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:129,891,918...129,952,489
Ensembl chr 8:132,866,245...132,926,514
JBrowse link
G NF2 neurofibromin 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:19487675 PMID:25401301 RGD:2315000 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013
JBrowse link
G NLRP12 NLR family pyrin domain containing 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr19:50,735,124...50,765,556
Ensembl chr19:59,582,005...59,614,436
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 disease_progression ISO RGD PMID:9663430 RGD:2299059 NCBI chr17:45,243,588...45,252,135
Ensembl chr17:50,113,622...50,131,636
JBrowse link
G NNMT nicotinamide N-methyltransferase ISO mRNA:increased expression:kidney RGD PMID:17070307 RGD:2299120 NCBI chr11:109,174,490...109,186,758
Ensembl chr11:113,016,613...113,029,581
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 severity
treatment
ISO RGD PMID:18181043 PMID:21531004 RGD:7174727 RGD:7174733 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma, somatic
ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO OMIM NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335
JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17621631 RGD:2299159 NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197
JBrowse link
G PBRM1 polybromo 1 ISO OMIM NCBI chr 3:52,487,083...52,626,418
Ensembl chr 3:53,718,051...53,850,146
JBrowse link
G PCNA proliferating cell nuclear antigen severity ISO RGD PMID:11369057 RGD:2315008 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G PDCD1 programmed cell death 1 disease_progression ISO RGD PMID:17363529 RGD:7248680 NCBI chr2B:129,111,509...129,121,127 JBrowse link
G PDGFRA platelet derived growth factor receptor alpha disease_progression ISO protein:increased expression:kidney RGD PMID:12866380 RGD:2292157 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO mRNA:increased expression:kidney RGD PMID:15994946 PMID:16865223 RGD:2290496 RGD:2292198 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 3:58,359,753...58,366,094
Ensembl chr 3:59,776,618...59,782,411
JBrowse link
G PDPN podoplanin disease_progression ISO RGD PMID:18291512 RGD:2292239 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584
JBrowse link
G PDXDC1 pyridoxal dependent decarboxylase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr16:13,722,703...13,785,674 JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25329396 NCBI chr12:115,716,953...115,726,412
Ensembl chr12:119,093,952...119,105,054
JBrowse link
G PGF placental growth factor disease_progression ISO protein:increased expression:plasma RGD PMID:14981951 RGD:13506645 NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964
JBrowse link
G PGK1 phosphoglycerate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr  X:67,280,269...67,302,307
Ensembl chr  X:77,391,805...77,414,459
JBrowse link
G PIDD1 p53-induced death domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Renal cell carcinoma
CTD
ClinVar
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression ISO RGD PMID:25757764 RGD:13504823 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G PLAU plasminogen activator, urokinase severity ISO mRNA:increased expression:kidney (human) RGD PMID:20544684 RGD:7241133 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136
JBrowse link
G PLD2 phospholipase D2 ISO protein:increased expression:kidney RGD PMID:11185526 RGD:2299898 NCBI chr17:4,853,919...4,870,254
Ensembl chr17:4,843,217...4,858,425
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 ISO mRNA:increased expression:kidney RGD PMID:11568975 RGD:2315108 NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347
JBrowse link
G PNKD PNKD metallo-beta-lactamase domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr2B:105,529,775...105,606,207
Ensembl chr2B:224,127,504...224,204,046
JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2844640 NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706
JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:tumor (rat) RGD PMID:476627 RGD:5135050 NCBI chr 4:67,491,407...67,533,822
Ensembl chr 4:74,059,966...74,102,002
JBrowse link
G PRCC proline rich mitotic checkpoint control factor ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 1:132,110,795...132,144,039
Ensembl chr 1:135,933,269...135,966,483
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 ISO DNA:snp:promoter:g.-151G>T (human) RGD PMID:11788900 RGD:9999148 NCBI chr 6:32,423,614...32,429,062
Ensembl chr 6:33,539,060...33,564,402
JBrowse link
G PTEN phosphatase and tensin homolog disease_progression ISO ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Renal cell carcinoma
CTD Direct Evidence: marker/mechanism
protein:decreased expression:kidney
protein:decreased expression:kidney (rat)
RGD
ClinVar
CTD
PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... RGD:12802360 RGD:1643331 RGD:2292500 RGD:2292513 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA:increased expression:kidney RGD PMID:12708469 RGD:2300212 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:kidney
CTD
RGD
PMID:12664575 PMID:12708469 PMID:17899436 RGD:2300204 RGD:2300212 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PVALB parvalbumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16927643 NCBI chr22:17,715,109...17,731,587
Ensembl chr22:35,551,448...35,568,316
JBrowse link
G RASSF1 Ras association domain family member 1 ISO DNA:hypermethylation:promoter RGD PMID:17645803 RGD:2299866 NCBI chr 3:50,255,897...50,267,042
Ensembl chr 3:51,491,548...51,502,392
JBrowse link
G RB1 RB transcriptional corepressor 1 disease_progression ISO RGD PMID:11549509 RGD:2299893 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney
CTD
RGD
PMID:12663495 PMID:17290398 PMID:18089796 RGD:2298755 RGD:2298771 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RNF139 ring finger protein 139 ISO OMIM NCBI chr 8:121,158,715...121,172,069
Ensembl chr 8:123,912,589...123,924,720
JBrowse link
G RPL14 ribosomal protein L14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 3:40,362,235...40,367,349
Ensembl chr 3:40,632,762...40,637,697
JBrowse link
G RYR1 ryanodine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr19:35,527,466...35,685,446
Ensembl chr19:44,106,036...44,256,327
JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21131975 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:23797736 NCBI chr 3:46,916,615...47,064,046
Ensembl chr 3:48,018,517...48,163,999
JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO mRNA:decreased expression:kidney RGD PMID:20420713 RGD:4107084 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18404682 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SHANK1 SH3 and multiple ankyrin repeat domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr19:47,623,474...47,684,476
Ensembl chr19:56,526,577...56,580,442
JBrowse link
G SKP2 S-phase kinase associated protein 2 disease_progression ISO RGD PMID:18922157 RGD:2315038 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7921415 NCBI chr 1:42,224,273...42,257,184
Ensembl chr 1:43,600,733...43,634,143
JBrowse link
G SLC49A4 solute carrier family 49 member 4 susceptibility ISO DNA:translocation:intron:t(2;3)(q35;q21) RGD PMID:11912179 RGD:1601072 NCBI chr 3:119,883,252...119,968,881
Ensembl chr 3:126,782,782...126,872,936
JBrowse link
G SLC5A3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr21:20,441,434...20,474,101 JBrowse link
G SMAD2 SMAD family member 2 severity ISO protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530
JBrowse link
G SMAD4 SMAD family member 4 severity ISO protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359
JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 disease_progression ISO RGD PMID:33532313 RGD:127285652 NCBI chr 3:47,487,948...47,683,623
Ensembl chr 3:48,590,221...48,781,248
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA, protein:increased expression:kidney RGD PMID:11679940 RGD:2300025 NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 disease_progression ISO protein:decreased expression:kidney
protein:increased expression:serum
RGD PMID:10508484 PMID:11176522 RGD:2300387 RGD:2300388 NCBI chr 5:143,273,137...143,287,745 JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr19:37,515,420...37,621,473
Ensembl chr19:46,042,387...46,127,429
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:kidney RGD PMID:16501837 RGD:2315090 NCBI chr11:125,001,771...125,021,371
Ensembl chr11:128,888,124...128,913,559
JBrowse link
G ST7 suppression of tumorigenicity 7 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 7:108,922,652...109,197,805
Ensembl chr 7:121,680,200...121,896,175
JBrowse link
G STAT3 signal transducer and activator of transcription 3 disease_progression ISO DNA:snp
protein:increased phosphorylation:kidney
RGD PMID:12131365 PMID:17602083 RGD:2291913 RGD:2291917 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G SYNE2 spectrin repeat containing nuclear envelope protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr14:44,438,851...44,807,710
Ensembl chr14:62,751,560...63,064,136
JBrowse link
G TAGLN2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:135,269,954...135,277,421 JBrowse link
G TERT telomerase reverse transcriptase ISO mRNA, protein:increased expression:kidney RGD PMID:18250061 RGD:2291980 NCBI chr 5:1,542,217...1,586,775
Ensembl chr 5:1,300,960...1,338,872
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 4:97,612,439...97,745,544
Ensembl chr 4:108,269,082...108,358,400
JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12917640 RGD:1599384 NCBI chr  X:41,326,802...41,341,574
Ensembl chr  X:49,182,795...49,197,194
JBrowse link
G TFRC transferrin receptor ISO protein:increased expression:kidney, T cell
mRNA:decreased expression:kidney, T cell
RGD PMID:8050820 PMID:12394762 RGD:2292024 RGD:2292025 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998
JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression ISO protein:increased expression:peripheral blood RGD PMID:25499257 PMID:26631499 PMID:26749573 RGD:11560966 RGD:13506173 RGD:13506175 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGM2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr20:34,450,845...34,488,106
Ensembl chr20:35,561,819...35,599,042
JBrowse link
G THRA thyroid hormone receptor alpha ISO DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr17:17,196,459...17,226,263 JBrowse link
G THRB thyroid hormone receptor beta ISO DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 disease_progression ISO protein:increased expression:kidney RGD PMID:11595703 RGD:2290350 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 disease_progression ISO mRNA:decreased expression:kidney
protein:increased expression:kidney
RGD PMID:17572184 PMID:18035688 RGD:2290358 RGD:2290359 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 ISO mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr 3:12,079,195...12,087,485
Ensembl chr 3:12,425,429...12,433,192
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:19384924 PMID:19904265 RGD:2315113 RGD:2315119 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO mRNA:increased expression:kidney RGD PMID:16865223 PMID:17184908 RGD:2290491 RGD:2290496 NCBI chr 8:22,440,502...22,476,790
Ensembl chr 8:19,378,547...19,414,724
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:serum (human) RGD PMID:7912320 RGD:5131437 NCBI chr12:6,457,617...6,470,969
Ensembl chr12:6,374,257...6,387,613
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO RGD PMID:20566746 RGD:7245512 NCBI chr 1:10,915,743...10,957,765
Ensembl chr 1:12,130,663...12,172,646
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:20403343 NCBI chr 3:169,512,491...169,530,706
Ensembl chr 3:177,694,021...177,712,137
JBrowse link
G TP53 tumor protein p53 disease_progression ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma, somatic
CTD
ClinVar
RGD
PMID:1349175 PMID:1565143 PMID:1565144 PMID:1644930 PMID:1737852 More... RGD:2290544 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TP73 tumor protein p73 ISO RGD PMID:9796703 RGD:2291837 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link
G TSC1 TSC complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 9:104,007,708...104,060,938
Ensembl chr 9:132,638,003...132,675,759
JBrowse link
G TSC2 TSC complex subunit 2 treatment ISO DNA:nonsense mutations;missense mutations; splice-site mutation:multiple RGD PMID:10029074 PMID:10096549 PMID:18695678 RGD:11568655 RGD:11568661 RGD:68666 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
G TYMP thymidine phosphorylase severity ISO protein:increased expression:kidney RGD PMID:12614261 PMID:16861722 RGD:2293717 RGD:2293723 NCBI chr22:30,772,088...30,776,618 JBrowse link
G UNC5C unc-5 netrin receptor C ISO CTD Direct Evidence: marker/mechanism CTD PMID:21600761 NCBI chr 4:87,527,262...87,921,351
Ensembl chr 4:98,205,554...98,587,888
JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO RGD PMID:19755989 RGD:2315455 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
G VEGFC vascular endothelial growth factor C ISO RGD PMID:19500329 RGD:2315476 NCBI chr 4:168,870,941...168,999,160
Ensembl chr 4:181,104,737...181,236,030
JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO OMIM NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234
JBrowse link
G VMO1 vitelline membrane outer layer 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:4,832,104...4,834,669
Ensembl chr17:4,821,474...4,822,623
JBrowse link
G VWF von Willebrand factor disease_progression ISO protein:increased expression:plasma RGD PMID:21953673 RGD:7207032 NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153
JBrowse link
G WIF1 WNT inhibitory factor 1 ISO DNA:hypermethylation:promoter RGD PMID:17145819 RGD:2291869 NCBI chr12:23,795,280...23,866,666
Ensembl chr12:24,299,351...24,370,807
JBrowse link
G WNT11 Wnt family member 11 ISO mRNA:increased expression:tumor:increased in a single case RGD PMID:11712081 RGD:2299947 NCBI chr11:71,239,781...71,263,915
Ensembl chr11:74,540,169...74,560,024
JBrowse link
G WNT2 Wnt family member 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862
JBrowse link
G XIAP X-linked inhibitor of apoptosis disease_progression ISO protein:increased expression:kidney RGD PMID:17332931 RGD:2315854 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:SNP: :p.R399Q RGD PMID:16510122 RGD:2302577 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
G YIPF3 Yip1 domain family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 6:43,103,900...43,109,033 JBrowse link
G ZNF536 zinc finger protein 536 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr19:27,145,499...27,634,609
Ensembl chr19:35,904,282...36,387,805
JBrowse link
G ZNF804A zinc finger protein 804A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr2B:71,872,807...72,216,720
Ensembl chr2B:189,942,181...190,019,736
JBrowse link
Renal Cell Carcinoma 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:24631838 PMID:26018084 PMID:26619011 PMID:27159400 PMID:27830187 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1349175 PMID:1565143 PMID:1565144 PMID:1644930 PMID:1737852 More... NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
Renal Cell Carcinoma, Xp11-Associated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TFE3 transcription factor binding to IGHM enhancer 3 ISO OMIM NCBI chr  X:41,326,802...41,341,574
Ensembl chr  X:49,182,795...49,197,194
JBrowse link
Sporadic Papillary Renal Cell Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:39,997,026...40,007,783
Ensembl chr  X:47,893,153...47,904,643
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:8589699 PMID:8845844 PMID:9438390 PMID:9843049 PMID:10471491 More... NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:514,227...559,838
Ensembl chr11:575,495...588,750
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24631838 PMID:26018084 PMID:26619011 PMID:27159400 PMID:27830187 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity ISO mRNA:increased expression:renal cortex (human)
protein:increased expression:kidney (human)
RGD PMID:17409424 PMID:19384955 RGD:7240562 RGD:7240563 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G RHEB Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 7:143,054,747...143,108,011 JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:1565143 PMID:7887414 PMID:8023157 PMID:8118819 PMID:8242631 More... NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13850
    disease of cellular proliferation 6609
      Neoplasms by Histologic Type 4547
        cell type cancer 3249
          carcinoma 2772
            renal carcinoma 335
              kidney carcinoma in situ 0
              renal cell carcinoma + 329
              renal pelvis carcinoma + 0
Path 2
Term Annotations click to browse term
  disease 13850
    disease of anatomical entity 13507
      Urogenital Diseases 3838
        urinary system disease 1685
          kidney disease 1482
            Kidney Neoplasms 416
              kidney cancer 389
                renal carcinoma 335
                  kidney carcinoma in situ 0
                  renal cell carcinoma + 329
                  renal pelvis carcinoma + 0
paths to the root