Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:renal cell carcinoma
go back to main search page
Accession:DOID:4450 term browser browse the term
Definition:A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney. (DO)
Synonyms:exact_synonym: Grawitz tumor;   RCC;   adenocarcinoma of kidney;   chromophil renal cell carcinoma;   hypernephroid carcinoma;   hypernephroid carcinomas;   hypernephroma;   hypernephromas;   nephroid carcinoma;   nephroid carcinomas;   renal adenocarcinoma;   renal cell adenocarcinoma;   renal cell adenocarcinomas;   renal cell cancer;   renal cell cancers;   renal cell carcinomas;   renal collecting duct carcinoma
 narrow_synonym: ADENOCARCINOMA OF KIDNEY NONPAPILLARY RENAL CARCINOMA 1 LOCUS;   NRC1;   renal cell carcinoma with paraneoplastic erythrocytosis;   renal cell carcinoma, somatic
 primary_id: MESH:D002292
 alt_id: OMIM:144700
 xref: GARD:13215;   NCI:C9385;   ORDO:217071
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A disease_progression ISO DNA:polymorphism: :3435C>T (human) RGD PMID:17177989 PMID:12089380 RGD:2315557, RGD:2315559 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 susceptibility ISO DNA:polymorphism: :p.Q141K (human) RGD PMID:15906349 RGD:2315569 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Ache acetylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acy1 aminoacylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 severity ISO RGD PMID:21511296 RGD:13831349 NCBI chr 7:106,404,844...106,476,902
Ensembl chr 7:106,404,958...106,476,902
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:29723618 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Afp alpha-fetoprotein ISO RGD PMID:1714107 RGD:2292042 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agtr1a angiotensin II receptor, type 1a severity ISO protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 disease_progression ISO protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Ahnak AHNAK nucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:205,882,223...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Akap13 A-kinase anchoring protein 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:kidney RGD PMID:17681738 RGD:1643331 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt3 AKT serine/threonine kinase 3 susceptibility ISO DNA:missense mutation:exon, intron:multiple RGD PMID:23378641 RGD:13503319 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Alad aminolevulinate dehydratase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21799727 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22743654 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:kidney RGD PMID:14654968 RGD:2315610 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amacr alpha-methylacyl-CoA racemase ISO RGD PMID:14707866 RGD:2315633 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Ang angiogenin ISO protein:increased expression:serum RGD PMID:18808740 RGD:2325699 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Angpt1 angiopoietin 1 severity ISO mRNA:altered expression:kidney RGD PMID:17505508 RGD:1643335 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Anxa1 annexin A1 IEP RGD PMID:14587099 RGD:7421570 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 IEP RGD PMID:14587099 RGD:7421570 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apc APC regulator of WNT signaling pathway onset
disease_progression
severity
ISO DNA,protein:LOH,decreased expression: :
DNA:LOH: :
RGD PMID:16116480 PMID:10426194 PMID:15203750 RGD:7242056, RGD:7242060, RGD:7242059 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Aprt adenine phosphoribosyl transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator treatment ISO DNA:missense mutation: :pF446L (human) RGD PMID:27595394 RGD:13503335 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Asb15 ankyrin repeat and SOCS box containing 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 4:53,021,553...53,050,846
Ensembl chr 4:53,031,692...53,049,928
JBrowse link
G Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 4:46,400,485...46,456,085
Ensembl chr 4:46,400,485...46,456,085
JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 ISO DNA:hypermethylation:promoter RGD PMID:21132003 RGD:14696812 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733
JBrowse link
G Aurka aurora kinase A ISO mRNA, protein:increased expression:kidney RGD PMID:17349527 RGD:1643346 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bad BCL2-associated agonist of cell death ISO RGD PMID:15851405 RGD:2292677 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 severity ISO RGD PMID:9894249 RGD:2315703 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:22683710 PMID:23797736 PMID:25231345 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Bche butyrylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator disease_progression ISO RGD PMID:17482919 PMID:18283311 RGD:2293019, RGD:2298896 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 ISO RGD PMID:12025227 RGD:1643483 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bik BCL2-interacting killer ISO protein:decreased expression:kidney RGD PMID:16322756 RGD:14394818 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 disease_progression ISO mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ISO mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO mRNA:splice variant
CTD Direct Evidence: therapeutic
protein:increased expression:kidney
CTD
RGD
PMID:16188142 PMID:12115583 PMID:17363528 RGD:2293108, RGD:2293102 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17437058 PMID:25401301 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606
JBrowse link
G Bmp4 bone morphogenetic protein 4 severity ISO RGD PMID:17644140 RGD:1643589 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO mRNA,protein:increased expression:kidney RGD PMID:20016212 RGD:7242419 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmp7 bone morphogenetic protein 7 disease_progression ISO RGD PMID:17644140 RGD:1643589 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bsg basigin (Ok blood group) disease_progression ISO protein:increased expression:kidney RGD PMID:17021824 RGD:2289052 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO mRNA:decreased expression:kidney RGD PMID:14996721 RGD:2289069 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Btg3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19221000 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
JBrowse link
G C4a complement C4A disease_progression ISO RGD PMID:19150565 RGD:5688259 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
JBrowse link
G C4b complement C4B (Chido blood group) disease_progression ISO RGD PMID:19150565 RGD:5688259 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Ca9 carbonic anhydrase 9 disease_progression ISO DNA, mRNA:hypomethylation, increased expression:promoter, kidney
protein:increased expression:serum, urine
RGD PMID:11506497 PMID:12966427 PMID:18464292 PMID:12883698 RGD:2293201, RGD:2293198, RGD:2293191, RGD:2293199 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP RGD PMID:7053379 RGD:10755426 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Capg capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
JBrowse link
G Card11 caspase recruitment domain family, member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Casp2 caspase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 ISO RGD PMID:17513560 RGD:2293308 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cav1 caveolin 1 disease_progression ISO protein:increased expression:kidney
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar
RGD
PMID:28492532 PMID:15247769 RGD:2289107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccnb1 cyclin B1 disease_progression ISO protein:increased expression:kidney RGD PMID:16557593 RGD:2315941 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 ISO DNA:polymorphism RGD PMID:15538282 PMID:17924468 RGD:2289130, RGD:2289127 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 disease_progression ISO RGD PMID:18679818 RGD:2316007 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 ISO mRNA, protein:increased expression:kidney RGD PMID:17726548 RGD:2289228 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:15282531 PMID:12594303 PMID:20426873 RGD:7248440, RGD:11522744, RGD:7248724 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd44 CD44 molecule (Indian blood group) disease_progression
severity
ISO protein:increased expression:kidney RGD PMID:12833185 PMID:17284111 RGD:2289360, RGD:2289351 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd46 CD46 molecule ISO RGD PMID:10744069 RGD:2293550 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Cdc14b cell division cycle 14B severity ISO mRNA:decreased expression:kidney: RGD PMID:24619757 RGD:10059341 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdh1 cadherin 1 disease_progression
onset
ISO protein:decreased expression, altered localization:kidney, nucleus
DNA:LOH: :
RGD PMID:17906660 PMID:15203750 RGD:2289489, RGD:7242059 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk2 cyclin dependent kinase 2 ISO RGD PMID:16740772 RGD:2293561 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:kidney RGD PMID:15991006 RGD:2293579 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B disease_progression ISO protein:decreased expression:kidney
mRNA, protein:increased expression:kidney
RGD PMID:17924468 PMID:18425369 PMID:18495610 RGD:2289127, RGD:2293590, RGD:2293589 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A IAGP
ISO
DNA:gene instability
DNA:deletion
DNA, protein:hypermethylation, increased expression:promoter, kidney
RGD PMID:11839561 PMID:17201148 PMID:15232742 RGD:1298747, RGD:2289680, RGD:2289699 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 ISO DNA:deletion
DNA:hypermethylation:promoter
RGD PMID:17201148 PMID:15232742 RGD:2289680, RGD:2289699
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 ISO DNA, protein:hypermethylation, increased expression:promoter, kidney
DNA:deletion
RGD PMID:15232742 PMID:17201148 RGD:2289699, RGD:2289680
G Cdkn2b cyclin-dependent kinase inhibitor 2B IAGP DNA:loss of heterozygosity, deletion RGD PMID:10391689 RGD:7248758 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cftr CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cnn2 calponin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 7:9,712,505...9,719,711
Ensembl chr 7:9,712,516...9,719,656
JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO DNA:polymorphism:exon RGD PMID:17220335 RGD:2289716 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cpq carboxypeptidase Q ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16254461 NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:22958305 RGD:6904212 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cryab crystallin, alpha B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO mRNA:increased expression:kidney RGD PMID:18592004 PMID:22052465 RGD:2299092, RGD:7257566 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csmd3 CUB and Sushi multiple domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:23797736 NCBI chr 7:78,747,322...80,066,466
Ensembl chr 7:78,748,480...80,066,369
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNPs:exons:rs3087243, rs231775 (human) RGD PMID:17678726 RGD:7204723 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctnna1 catenin alpha 1 disease_progression ISO protein:decreased expression:kidney RGD PMID:9355975 RGD:2289799 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 disease_progression ISO protein:increased expression:kidney RGD PMID:11831984 PMID:15330191 RGD:2289835, RGD:2289794 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cul7 cullin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:16210641 RGD:7257682 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 no_association ISO
IEP
DNA:polymorphism: :p.I462V (human)
DNA:SNPs: :6235T>C, 4889A>G, 4887C>A (human)
RGD PMID:22296350 PMID:11115552 PMID:9631944 PMID:22000673 RGD:7257729, RGD:7296938, RGD:7296939, RGD:7296937 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dnhd1 dynein heavy chain domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 1:159,990,785...160,077,990
Ensembl chr 1:159,990,438...160,074,858
JBrowse link
G Ebag9 estrogen receptor binding site associated, antigen, 9 disease_progression ISO RGD PMID:15867365 RGD:2289852 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egfr epidermal growth factor receptor ISO protein:increased expression:tumor RGD PMID:18467719 RGD:2293730 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISO protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr19:52,867,914...52,907,169 JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 ISO protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO protein:increased expression:serum RGD PMID:20676679 RGD:13506732 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Eloc elongin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21131975 PMID:12750296 RGD:10395373 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:kidney
CTD
RGD
PMID:10897039 PMID:17296437 PMID:15360049 RGD:2289930, RGD:2289987 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO mRNA, protein:decreased expression:kidney RGD PMID:15360049 RGD:2289987 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Fas Fas cell surface death receptor ISO DNA:missense mutations:exon
protein:increased expression:serum
RGD PMID:11435457 PMID:12460460 PMID:10654915 PMID:17031406 RGD:2290132, RGD:2290131, RGD:2290133, RGD:2290099 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand ISO RGD PMID:17641033 PMID:11435457 RGD:2290051, RGD:2290132 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:1718278 RGD:2290303 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 disease_progression ISO RGD PMID:25900027 RGD:11352663 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fh fumarate hydratase ISO RGD PMID:17211469 RGD:6907135 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO RGD PMID:10530564 PMID:17539022 RGD:2289903, RGD:2289870 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Flcn folliculin treatment IAGP
IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:12204536 PMID:14769940 PMID:16369488 RGD:1302869, RGD:13605606 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic
protein:increased expression:kidney, blood, myeloid cell
CTD
RGD
PMID:16596207 PMID:11846206 PMID:18566400 RGD:2289960, RGD:2301250 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fmn2 formin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr13:86,454,256...86,771,437 JBrowse link
G Fn1 fibronectin 1 severity ISO RGD PMID:20860816 RGD:7205637 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 2:244,099,031...244,119,967
Ensembl chr 2:244,099,076...244,119,899
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 disease_progression ISO RGD PMID:25900027 RGD:11352663 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743
JBrowse link
G Ghrh growth hormone releasing hormone ISO RGD PMID:10962030 RGD:2301426 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18264126 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Grb7 growth factor receptor bound protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:decreased expression:kidney: RGD PMID:18312938 RGD:7257550 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18566013 PMID:26656529 PMID:14504370 RGD:2293845 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15108329 PMID:20464042 RGD:8547946 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18566013 PMID:26656529 PMID:14504370 RGD:2293845 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 disease_progression ISO RGD PMID:23352434 RGD:7245470 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 susceptibility ISO DNA:polymorphisms: :-574G>T, +4259T>G (human) RGD PMID:22472081 RGD:7245505 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha disease_progression ISO RGD PMID:19302703 RGD:2306222 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hnf1a HNF1 homeobox A ISO OMIM NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf1b HNF1 homeobox B ISO OMIM NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
JBrowse link
G Hoxb13 homeo box B13 disease_progression ISO DNA:hypermethylation RGD PMID:16278676 RGD:2314729 NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP RGD PMID:17952403 RGD:7242846 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:18076934 RGD:2290003 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 IEP mRNA:decreased expression:kidney RGD PMID:10854235 RGD:1626565 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
JBrowse link
G Il13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22317767 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO RGD PMID:17031403 RGD:6907413 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:21812652 RGD:5147871 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4r interleukin 4 receptor susceptibility
disease_progression
ISO DNA:polymorphism:cds:p.I50V (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22317767 PMID:30472377 PMID:22317767 PMID:12171893 RGD:7207066, RGD:7207070 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Insr insulin receptor ISO RGD PMID:15753986 RGD:2290462 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:16006965 RGD:1549443 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jup junction plakoglobin ISO RGD PMID:15701841 PMID:9891472 RGD:2291866, RGD:2291890 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 ISO DNA, mRNA, protein:hypermethylation, decreased expression:kidney RGD PMID:12133830 RGD:2315654 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 ISO protein:increased expression:kidney (human) RGD PMID:18777199 RGD:9693695 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kdm4c lysine demethylase 4C ISO DNA:deletion:cds (human) RGD PMID:22483639 RGD:9587741 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818
JBrowse link
G Kdm5c lysine demethylase 5C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870
JBrowse link
G Kdm6a lysine demethylase 6A ISO mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kdm6b lysine demethylase 6B ISO mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kdr kinase insert domain receptor treatment ISO RGD PMID:17653245 PMID:16763608 PMID:17332933 RGD:2301756, RGD:126925190, RGD:8552363 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO chromophobe RCC only
papillary RCC only
RGD PMID:15780567 PMID:15073597 RGD:2292414, RGD:2292421 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Klk6 kallikrein related-peptidase 6 ISO protein:decreased expression:kidney RGD PMID:16340244 RGD:2314864 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO mRNA:increased expression:kidney RGD PMID:11851621 RGD:2314914 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt32 keratin 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:85,013,555...85,020,534
Ensembl chr10:85,013,554...85,020,534
JBrowse link
G Krt7 keratin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 PMID:16927643 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G L1cam L1 cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21097529 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Ldhb lactate dehydrogenase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Lep leptin resistance ISO RGD PMID:19278051 RGD:6907119 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lman2l lectin, mannose-binding 2-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 9:38,683,174...38,685,249
Ensembl chr 9:38,661,712...38,685,337
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO RGD PMID:17692401 RGD:2314919 NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
JBrowse link
G LOC102552284 zinc finger protein 420-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301
G Lrp1b LDL receptor related protein 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 3:24,594,302...26,715,037 JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Ltf lactotransferrin ISO RGD PMID:23201854 RGD:7243106 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G M6pr mannose-6-phosphate receptor, cation dependent ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 4:155,501,080...155,510,219
Ensembl chr 4:155,500,921...155,510,216
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor susceptibility ISO RGD PMID:8649854 RGD:1599220 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO RGD PMID:7664295 PMID:18172299 RGD:2292629, RGD:2292630 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 susceptibility ISO DNA:missense mutation: :multiple RGD PMID:22517515 RGD:13504815 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More... RGD:1600122 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mgp matrix Gla protein disease_progression ISO RGD PMID:1399132 RGD:2293578 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mitf melanocyte inducing transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22012259 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mlh1 mutL homolog 1 ISO protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mllt10 MLLT10, histone lysine methyltransferase DOT1L cofactor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:80,821,870...80,949,349
Ensembl chr17:80,822,556...80,949,345
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility
no_association
ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:12845675 PMID:17980059 RGD:7207023, RGD:7207082 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO protein:increased expression:kidney
mRNA:decreased expression:kidney
RGD PMID:17572184 PMID:18035688 RGD:2290359, RGD:2290358 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO DNA:missense mutation:cds:p.E45K rs679620 (human) RGD PMID:15319295 PMID:19551141 RGD:7207067, RGD:7241233 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO mRNA:increased expression:kidney RGD PMID:18035688 RGD:2290358 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mok MOK protein kinase ISO mRNA:increased expression:kidney RGD PMID:15900605 RGD:7243170 NCBI chr 6:129,823,794...129,854,669
Ensembl chr 6:129,823,795...129,854,700
JBrowse link
G Msgn1 mesogenin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 6:33,912,787...33,913,427
Ensembl chr 6:33,912,787...33,913,427
JBrowse link
G Msh2 mutS homolog 2 ISO protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:missense mutation:cds:p.A222V (rs1801133) (human) RGD PMID:18098291 RGD:6893654 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal cell cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:20190810 PMID:22729223 PMID:23797736 PMID:24631838 PMID:25599672 More... RGD:7207420 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO RGD PMID:10390012 RGD:7245968 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc4 mucin 4, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO
IEP
mRNA:increased expression:kidney (human)
protein:increased expression:kidney (rat)
RGD PMID:21982273 PMID:18055543 RGD:7207793, RGD:7207841 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nav3 neuron navigator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:25401301 PMID:19487675 RGD:2315000 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 disease_progression ISO RGD PMID:9663430 RGD:2299059 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nnmt nicotinamide N-methyltransferase ISO mRNA:increased expression:kidney RGD PMID:17070307 RGD:2299120 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 severity
treatment
ISO RGD PMID:21531004 PMID:18181043 RGD:7174727, RGD:7174733 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma, somatic
ClinVar Annotator: match by term: Hypernephroma
ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP
ISO
OMIM
RGD
PMID:18218111 PMID:10987279 RGD:2317140, RGD:1600295 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Olr659 olfactory receptor 659 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 3:74,582,417...74,583,346
Ensembl chr 3:74,579,912...74,593,375
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17621631 PMID:17621631 RGD:2299159 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pbrm1 polybromo 1 ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
RGD
PMID:22138691 PMID:23797736 PMID:21654818 RGD:6907137 NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Pcna proliferating cell nuclear antigen severity ISO RGD PMID:11369057 RGD:2315008 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdcd1 programmed cell death 1 disease_progression ISO RGD PMID:17363529 RGD:7248680 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha disease_progression ISO protein:increased expression:kidney RGD PMID:12866380 RGD:2292157 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO mRNA:increased expression:kidney RGD PMID:15994946 PMID:16865223 RGD:2292198, RGD:2290496 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdpn podoplanin disease_progression ISO RGD PMID:18291512 RGD:2292239 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr10:2,025,056...2,113,712
Ensembl chr10:2,025,360...2,113,520
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25329396 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase ISO RGD PMID:6722784 RGD:5135276 NCBI chr10:53,690,301...53,711,811
Ensembl chr10:53,691,626...53,708,420
JBrowse link
G Pgf placental growth factor disease_progression ISO protein:increased expression:plasma RGD PMID:14981951 RGD:13506645 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pgk1 phosphoglycerate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pidd1 p53-induced death domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal cell carcinoma, somatic
CTD
ClinVar
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression ISO RGD PMID:25757764 RGD:13504823 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plau plasminogen activator, urokinase severity ISO mRNA:increased expression:kidney (human) RGD PMID:20544684 RGD:7241133 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pld2 phospholipase D2 ISO protein:increased expression:kidney RGD PMID:11185526 RGD:2299898 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 ISO mRNA:increased expression:kidney RGD PMID:11568975 RGD:2315108 NCBI chr 3:162,011,884...162,060,137
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2844640 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IEP protein:increased activity:tumor (rat) RGD PMID:476627 RGD:5135050 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16179254 NCBI chr  X:98,567,994...98,574,654
Ensembl chr  X:98,569,415...98,572,096
JBrowse link
G Prcc proline rich mitotic checkpoint control factor ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 2:173,326,261...173,351,799
Ensembl chr 2:173,326,259...173,351,825
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 ISO DNA:snp:promoter:g.-151G>T (human) RGD PMID:11788900 RGD:9999148 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Pten phosphatase and tensin homolog disease_progression ISO
IEP
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma
protein:decreased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... RGD:1643331, RGD:12802360, RGD:2292513, RGD:2292500 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP mRNA:increased expression:kidney RGD PMID:12708469 RGD:2300212 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 disease_progression IEP
ISO
mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12664575 PMID:12708469 PMID:17899436 RGD:2300212, RGD:2300204 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pvalb parvalbumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16927643 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Rassf1 Ras association domain family member 1 ISO DNA:hypermethylation:promoter RGD PMID:17645803 PMID:12222680 RGD:2299866, RGD:2291977 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164
JBrowse link
G Rb1 RB transcriptional corepressor 1 disease_progression ISO RGD PMID:11549509 RGD:2299893 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney
CTD
RGD
PMID:18089796 PMID:17290398 PMID:12663495 RGD:2298755, RGD:2298771 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rnf139 ring finger protein 139 ISO OMIM
RGD
PMID:9689122 PMID:17539022 RGD:1599629, RGD:2289870 NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009
JBrowse link
G Rpl14 ribosomal protein L14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 8:120,286,035...120,288,912
Ensembl chr 8:120,284,645...120,289,064
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility
disease_progression
ISO RGD PMID:9044854 PMID:10895068 PMID:12771724 RGD:2314704, RGD:2314701, RGD:2314695 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Ryr1 ryanodine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21131975 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO RGD PMID:21771581 RGD:6907134 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D ISO RGD PMID:21771581 RGD:6907134 NCBI chr 8:50,944,717...50,954,298
Ensembl chr 8:50,944,704...50,954,238
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22138691 PMID:23797736 PMID:21654818 RGD:6907137 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO mRNA:decreased expression:kidney RGD PMID:20420713 RGD:4107084 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18404682 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824
JBrowse link
G Skp2 S-phase kinase associated protein 2 disease_progression ISO RGD PMID:18922157 RGD:2315038 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7921415 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc49a4 solute carrier family 49 member 4 susceptibility ISO DNA:translocation:intron:t(2;3)(q35;q21) RGD PMID:11912179 RGD:1601072 NCBI chr11:64,995,629...65,068,929
Ensembl chr11:64,995,679...65,068,926
JBrowse link
G Slc5a3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Smad2 SMAD family member 2 severity ISO protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad4 SMAD family member 4 severity ISO protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 disease_progression ISO RGD PMID:33532313 RGD:127285652 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO mRNA, protein:increased expression:kidney RGD PMID:11679940 RGD:2300025 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 disease_progression ISO protein:decreased expression:kidney
protein:increased expression:serum
RGD PMID:10508484 PMID:11176522 RGD:2300388, RGD:2300387 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:kidney RGD PMID:16501837 RGD:2315090 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G ST7 suppression of tumorigenicity 7 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 4:46,041,655...46,289,745
Ensembl chr 4:46,042,236...46,289,740
JBrowse link
G Stat3 signal transducer and activator of transcription 3 disease_progression ISO DNA:snp
protein:increased phosphorylation:kidney
RGD PMID:17602083 PMID:12131365 RGD:2291913, RGD:2291917 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 6:94,537,088...94,848,085 JBrowse link
G Tagln2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
JBrowse link
G Terc telomerase RNA component ISO RNA:decreased expression:kidney RGD PMID:11156238 RGD:2291972 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA, protein:increased expression:kidney RGD PMID:18250061 RGD:2291980 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12917640 RGD:1599384 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571
JBrowse link
G Tfrc transferrin receptor ISO protein:increased expression:kidney, T cell
mRNA:decreased expression:kidney, T cell
RGD PMID:12394762 PMID:8050820 RGD:2292024, RGD:2292025 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO protein:increased expression:peripheral blood RGD PMID:26749573 PMID:25499257 PMID:26631499 RGD:11560966, RGD:13506175, RGD:13506173 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thra thyroid hormone receptor alpha ISO DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta ISO DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 disease_progression ISO protein:increased expression:kidney RGD PMID:11595703 RGD:2290350 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 disease_progression ISO protein:increased expression:kidney
mRNA:decreased expression:kidney
RGD PMID:17572184 PMID:18035688 RGD:2290359, RGD:2290358 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Tlr9 toll-like receptor 9 severity ISO protein:decreased expression:tumor, cytoplasm (human) RGD PMID:21929816 RGD:7246915 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:19384924 PMID:19904265 RGD:2315119, RGD:2315113 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b ISO mRNA:increased expression:kidney RGD PMID:16865223 PMID:17184908 RGD:2290496, RGD:2290491 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:serum (human) RGD PMID:7912320 RGD:5131437 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO RGD PMID:20566746 RGD:7245512 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:20403343 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 disease_progression ISO ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal cell cancer
ClinVar Annotator: match by term: Hypernephroma
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Renal cell carcinoma, somatic
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:1349175 PMID:1565143 PMID:1565144 PMID:1644930 PMID:1737852 More... RGD:2290544 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp73 tumor protein p73 ISO RGD PMID:9796703 RGD:2291837 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tsc1 TSC complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
G Tsc2 TSC complex subunit 2 treatment ISO
IAGP
IMP
DNA:nonsense mutations;missense mutations; splice-site mutation:multiple RGD PMID:10096549 PMID:10029074 PMID:18695678 RGD:11568655, RGD:68666, RGD:11568661 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Txnip thioredoxin interacting protein IDA DNA, mRNA, protein:hypermethylation, decreased expression:promoter, kidney RGD PMID:15834431 RGD:1642756 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Tymp thymidine phosphorylase severity ISO protein:increased expression:kidney RGD PMID:12614261 PMID:16861722 RGD:2293723, RGD:2293717 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Unc5c unc-5 netrin receptor C ISO CTD Direct Evidence: marker/mechanism CTD PMID:21600761 NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked ISO mRNA, protein:increased expression:kidney (human) RGD PMID:21654818 PMID:23057811 RGD:6907137, RGD:9587837 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422
JBrowse link
G Vdr vitamin D receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO RGD PMID:19755989 RGD:2315455 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C ISO RGD PMID:19500329 RGD:2315476 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
RGD
PMID:9137812 PMID:10340905 PMID:11171960 PMID:11986208 PMID:15177666 More... RGD:1580367 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
G Vmo1 vitelline membrane outer layer 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr10:55,227,944...55,234,794
Ensembl chr10:55,227,944...55,229,289
JBrowse link
G Vwf von Willebrand factor disease_progression ISO protein:increased expression:plasma RGD PMID:21953673 RGD:7207032 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wif1 Wnt inhibitory factor 1 ISO DNA:hypermethylation:promoter RGD PMID:17145819 RGD:2291869 NCBI chr 7:56,548,058...56,618,364
Ensembl chr 7:56,548,053...56,618,360
JBrowse link
G Wnt11 Wnt family member 11 ISO RGD PMID:11712081 RGD:2299947 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294
JBrowse link
G Wnt2 Wnt family member 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:28492532 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Xiap X-linked inhibitor of apoptosis disease_progression ISO protein:increased expression:kidney RGD PMID:17332931 RGD:2315854 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:SNP: :p.R399Q RGD PMID:16510122 RGD:2302577 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Yipf3 Yip1 domain family, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 9:14,730,289...14,735,644
Ensembl chr 9:14,730,284...14,735,641
JBrowse link
G Zfp536 zinc finger protein 536 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 1:90,000,359...90,463,423
Ensembl chr 1:90,002,858...90,462,990
JBrowse link
G Zfp804a zinc finger protein 804A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 3:67,033,481...67,267,769
Ensembl chr 3:67,034,170...67,263,607
JBrowse link
chromophobe renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A ISO ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:9392505 PMID:9754819 PMID:10966642 PMID:11393552 PMID:15649945 More... NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf1b HNF1 homeobox B ISO ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:15649945 PMID:16371430 PMID:25536396 PMID:25700310 PMID:25741868 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
JBrowse link
clear cell renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO mRNA:increased expression:renal cortex (human) RGD PMID:21947243 RGD:7244181 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 ISO RGD PMID:28672194 RGD:14696810 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b ISO RGD PMID:28672194 RGD:14696810 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP ISO RGD PMID:28672194 RGD:14696810 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 disease_progression ISO RGD PMID:23788753 RGD:13506731 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Eng endoglin severity ISO protein:increased expression:tumor, vasculature (human)
protein:decreased expression:kidney, tumor (human)
RGD PMID:22204709 PMID:16536758 RGD:7248775, RGD:7248780 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Ep300 E1A binding protein p300 severity ISO mRNA:altered expression:kidney, tumor (human)
mRNA, protein:increased expression:kidney
RGD PMID:23029358 PMID:28551630 RGD:7296925, RGD:15036804 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:brain RGD PMID:22065054 RGD:6893520 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G Gata1 GATA binding protein 1 disease_progression ISO RGD PMID:25230694 RGD:149735195 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gata2 GATA binding protein 2 disease_progression ISO RGD PMID:25230694 RGD:149735195 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:10383153 RGD:6906878 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hnf1a HNF1 homeobox A ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:8866553 PMID:8945470 PMID:9032114 PMID:9045858 PMID:9075818 More... NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO xenograph of human clear cell renal cancer cells in mouse RGD PMID:19509240 RGD:7242921 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Kat8 lysine acetyltransferase 8 ISO mRNA, protein:decreased expression:kidney (human) RGD PMID:23394073 RGD:9586034 NCBI chr 1:182,524,355...182,536,638 JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO RGD PMID:11576837 RGD:2290421 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
severity
ISO DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) RGD PMID:21489764 PMID:20039875 RGD:6893474, RGD:6893632 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor severity ISO protein:increased expression:kidney (human) RGD PMID:21881486 RGD:7207420 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:10987279 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Pak4 p21 (RAC1) activated kinase 4 disease_progression ISO RGD PMID:25744653 RGD:13504816 NCBI chr 1:83,849,904...83,889,188
Ensembl chr 1:83,849,904...83,859,413
JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 disease_progression ISO RGD PMID:24715215 RGD:13506722 NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975
JBrowse link
G Pbrm1 polybromo 1 ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:25911086 NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Pdgfb platelet derived growth factor subunit B disease_progression ISO RGD PMID:25766258 PMID:23879920 RGD:13504817, RGD:13506650 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pml PML nuclear body scaffold ISO protein:decreased expression:kidney (human) RGD PMID:25293974 RGD:41404694 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase severity ISO DNA:SNPs,loss of heterozygosity:multiple (human)
DNA:mutations:multiple (human)
RGD PMID:26864202 PMID:26891804 RGD:150429635, RGD:150429640 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:144,061,463...144,089,229
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Tp53 tumor protein p53 ISO mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
hereditary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1 deoxyribonuclease 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Egf epidermal growth factor ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar PMID:28492532 PMID:28546994 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
JBrowse link
G Trap1 TNF receptor-associated protein 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
nonpapillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1 calcium/calmodulin-dependent protein kinase I ISO ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary ClinVar NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081
JBrowse link
G Flcn folliculin ISS
ISO
OMIM:144700
ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary
MouseDO
ClinVar
PMID:15805188 PMID:15852235 PMID:16199547 PMID:18234728 PMID:19457309 More... NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Hnf1a HNF1 homeobox A ISS
ISO
OMIM:144700
ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary
MouseDO
ClinVar
PMID:25741868 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf1b HNF1 homeobox B ISS OMIM:144700 MouseDO NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISS
ISO
OMIM:144700
ClinVar Annotator: match by term: Renal cell carcinoma, nonpapillary
MouseDO
ClinVar
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Pbrm1 polybromo 1 ISS OMIM:144700 MouseDO NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Rnf139 ring finger protein 139 ISS OMIM:144700 MouseDO NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISS OMIM:144700 MouseDO NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
papillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 4:46,400,485...46,456,085
Ensembl chr 4:46,400,485...46,456,085
JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:10571946 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cftr CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26822237 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Eloc elongin C ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:8589699 PMID:8845844 PMID:9438390 PMID:9843049 PMID:10471491 More... NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar
OMIM
PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More... NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Msh2 mutS homolog 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:18325052 PMID:21926548 PMID:24506336 PMID:24763289 PMID:25637381 More... NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:20190810 PMID:22729223 PMID:24631838 PMID:25599672 PMID:25741868 More... NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Prcc proline rich mitotic checkpoint control factor ISO OMIM NCBI chr 2:173,326,261...173,351,799
Ensembl chr 2:173,326,259...173,351,825
JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rheb Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:18728283 PMID:19576851 PMID:22835832 PMID:24055113 PMID:24092654 More... NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300
JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:26619011 NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759
JBrowse link
G ST7 suppression of tumorigenicity 7 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 4:46,041,655...46,289,745
Ensembl chr 4:46,042,236...46,289,740
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1
ClinVar PMID:1349175 PMID:1565143 PMID:1565144 PMID:1644930 PMID:1737852 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:7660122 PMID:7728151 PMID:7784063 PMID:7987306 PMID:7987327 More... NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
G Wnt2 Wnt family member 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:28492532 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
Renal Cell Carcinoma 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:20190810 PMID:22729223 PMID:24631838 PMID:25599672 PMID:25799227 More... NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:9467011 PMID:9915974 PMID:10866302 PMID:11504908 PMID:11875759 More... NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1349175 PMID:1565143 PMID:1565144 PMID:1644930 PMID:1737852 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
Renal Cell Carcinoma, Xp11-Associated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfe3 transcription factor binding to IGHM enhancer 3 ISO OMIM NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571
JBrowse link
Sporadic Papillary Renal Cell Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:8589699 PMID:8845844 PMID:9438390 PMID:9843049 PMID:10471491 More... NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:20190810 PMID:24631838 PMID:26018084 PMID:26619011 PMID:27159400 More... NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor severity ISO mRNA:increased expression:renal cortex (human)
protein:increased expression:kidney (human)
RGD PMID:19384955 PMID:17409424 RGD:7240562, RGD:7240563 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Rheb Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:1565143 PMID:7887414 PMID:8023157 PMID:8118819 PMID:8242631 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17289
    disease of cellular proliferation 7054
      cancer 5018
        cell type cancer 3413
          carcinoma 2931
            adenocarcinoma 1485
              renal cell carcinoma 346
                Papillary Thyroid Carcinoma, with Papillary Renal Neoplasia 0
                Renal Cell Carcinoma 1 5
                Renal Cell Carcinoma, Xp11-Associated 1
                childhood kidney cell carcinoma 0
                chromophobe renal cell carcinoma + 2
                clear cell renal cell carcinoma 36
                collecting duct carcinoma 0
                hereditary renal cell carcinoma + 13
                mucinous tubular and spindle renal cell carcinoma 0
                multilocular clear cell renal cell carcinoma 0
                papillary renal cell carcinoma + 31
                sarcomatoid renal cell carcinoma 0
Path 2
Term Annotations click to browse term
  disease 17289
    disease of cellular proliferation 7054
      Neoplasms by Site 6698
        Urogenital Neoplasms 2007
          Urologic Neoplasms 638
            urinary system cancer 587
              kidney cancer 410
                renal carcinoma 352
                  renal cell carcinoma 346
                    Papillary Thyroid Carcinoma, with Papillary Renal Neoplasia 0
                    Renal Cell Carcinoma 1 5
                    Renal Cell Carcinoma, Xp11-Associated 1
                    childhood kidney cell carcinoma 0
                    chromophobe renal cell carcinoma + 2
                    clear cell renal cell carcinoma 36
                    collecting duct carcinoma 0
                    hereditary renal cell carcinoma + 13
                    mucinous tubular and spindle renal cell carcinoma 0
                    multilocular clear cell renal cell carcinoma 0
                    papillary renal cell carcinoma + 31
                    sarcomatoid renal cell carcinoma 0
paths to the root