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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Ebola virus disease
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Accession:DOID:4325 term browser browse the term
Definition:A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Bundibugyo virus (Orthoebolavirus bundibugyoense), Sudan ebolavirus (Orthoebolavirus sudanense), Tai Forest ebolavirus (Orthoebolavirus taiense), or Zaire ebolavirus (Orthoebolavirus zairense), which are transmitted_by contact with the body fluids of an infected animal or person, transmitted by contaminated fomites, or transmitted by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding. (DO)
Synonyms:exact_synonym: Ebola;   Ebola Infection;   Ebola disease;   Ebola hemorrhagic fever;   Ebola virus infection
 xref: EFO:0007243;   GARD:2035;   ICD10CM:A98.4;   MESH:D019142;   MONDO:0005737;   NCI:C36171
For additional species annotation, visit the Alliance of Genome Resources.

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Ebola virus disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD163 CD163 molecule exacerbates ISO protein:increased expression:blood plasma (human) RGD PMID:30666927 RGD:149735528 NCBI chr11:7,501,562...7,536,332
Ensembl chr11:7,501,150...7,536,295 		JBrowse link
G IL3 interleukin 3 ISO protein: reduced expression: plasma RGD PMID:20957152 RGD:5686879 NCBI chr23:34,894,630...34,899,105 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15606
    disease by infectious agent 2126
      viral infectious disease 1637
        RNA Virus Infections 1356
          Viral Hemorrhagic Fevers 27
            Ebola virus disease 2
Path 2
Term Annotations click to browse term
  disease 15606
    disease by infectious agent 2126
      viral infectious disease 1637
        RNA Virus Infections 1356
          Mononegavirales Infections 99
            Filoviridae Infections 2
              Ebola virus disease 2
paths to the root